Corneal autofluorescence in relation to permeability of the blood-aqueous barrier in diabetic patients with clinically significant macular edema and in an age-matched control group.

abstract：PURPOSE:To study the effect of Na-K pump and K(ATP) channel inhibition on the diameter and the adenosine-induced vasodilation of small retinal arterioles. METHODS:Thirty isolated porcine arterioles with a diameter of approximately 70 microm were mounted in a double-barrelled pipette system placed in an organ bath, and...

journal_title：Current eye research

authors： Jeppesen P,Aalkjaer C,Bek T

更新日期：2002-07-01 00:00:00

abstract：:The corneal endothelium is known to contain gap junctions on its lateral borders. Here we show that the endothelial cells of the rabbit cornea are highly dye coupled. Lucifer Yellow CH introduced into a single cell through either an intracellular glass microelectrode or a patch electrode rapidly spreads into its neigh...

journal_title：Current eye research

authors： Rae JL,Lewno AW,Cooper K,Gates P

更新日期：1989-08-01 00:00:00

abstract：:In an attempt to determine the factors involved in ocular pigment variation, the eyes of pallid mice (c57BL/6J-Pa/Pa), and those of littermate black mice (C57BL/6J-+/Pa) were examined ultrastructurally, histochemically, and biochemically. As controls, the eyes of black and congenic albino mice (C57BL/6J +/C2J and -C2J...

journal_title：Current eye research

authors： Ito M,Hashimoto K,Organisciak DT

更新日期：1982-01-01 00:00:00

abstract：:Purpose/Aim of the study: A recently proposed technique enables the generation of continuously increasing mosaic images of the corneal sub-basal nerve plexus (SNP) using in vivo corneal confocal microscopy (CCM). The aim of the present study was to investigate the progression of the corneal nerve fiber length (CNFL) m...

journal_title：Current eye research

authors： Allgeier S,Winter K,Bretthauer G,Guthoff RF,Peschel S,Reichert KM,Stachs O,Köhler B

更新日期：2017-04-01 00:00:00

abstract：:In an earlier study we isolated three cyanogen bromide cleavage fragments of bovine IRBP that exhibited high levels of immunopathogenicity, producing inflammatory changes in the eyes (EAU) and pineal gland (EAP) of Lewis rats. These fragments have been localized within the IRBP sequence. In order to identify these put...

journal_title：Current eye research

authors： Sanui H,Redmond TM,Hu LH,Kuwabara T,Margalit H,Cornette JL,Wiggert B,Chader GJ,Gery I

更新日期：1988-07-01 00:00:00

abstract：PURPOSE:To determine the effects of a subconjunctival injection of mitomycin-C (MMC) on iridial circulation in rabbits. METHODS:Dutch rabbits anesthetized with pentobarbital received a 0.2-ml subconjunctival injection of 0.4 mg/ml or 0.1 mg/ml MMC; the contralateral eye received 0.2 ml physiological saline. Intraocula...

journal_title：Current eye research

authors： Tomidokoro A,Araie M,Tamaki Y,Muta K

更新日期：1999-08-01 00:00:00

abstract：:Two of the major in vitro phosphorylated polypeptides of the bovine lens have been identified. Analysis by means of two-dimensional gel electrophoresis (IEF) has demonstrated that the lens phosphorylated 57,000 and 43,000 dalton polypeptides correspond in mobility to purified phosphorylated bovine lens vimentin and ch...

journal_title：Current eye research

authors： Sredy J,Roy D,Spector A

更新日期：1984-12-01 00:00:00

abstract：PURPOSE:Several previous studies have shown that glycoconjugates of extracellular matrix, cell membrane and nucleus play an important role in the mediation of cell proliferation, migration and differentiation. Lens epithelial cells and lens fiber cells show regional differences with regard to these parameters. If glyco...

journal_title：Current eye research

authors： Denk PO,Breipohl W,Naib-Majani W,Knorr M

更新日期：1997-06-01 00:00:00

abstract：:Vernier and grating acuity were measured in infants up to 6 months of age using a two-alternative forced-choice preferential looking technique. Vernier resolution was measured using a horizontal vernier grating. The grating was presented on half of the screen while the other half contained horizontal lines which were ...

journal_title：Current eye research

authors： Manny RE,Klein SA

更新日期：1984-03-01 00:00:00

abstract：PURPOSE:Unstable tear film characterized by shorting of tear break-up time (BUT) is associated with discomfort and dryness in contact lens wearers. The glycocalyx is thought to be crucial in maintaining the wettability and lubrication of the ocular surface. We evaluated the ocular surface glycocalyx in soft contact len...

journal_title：Current eye research

authors： Fukui M,Yamada M,Akune Y,Shigeyasu C,Tsubota K

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:To compare the quality of corneal endothelium of precut Descemet-stripping automated endothelial keratoplasty (DSAEK) tissue when transported with and without the anterior lamellar corneal tissue (ALCT) when organ-culture corneal storage methods are used. METHODS:After microkeratome-assisted excision of anteri...

journal_title：Current eye research

authors： Jhanji V,Pollock GA,Mackey AL,Beltz J,Vajpayee RB

更新日期：2012-02-01 00:00:00

abstract：PURPOSE:To evaluate the stability of successive applanation tonometry measurements in glaucomatous eyes. METHODS:A prospective, comparative, randomized, and evaluator-masked study was conducted in a tertiary medical center. Sixty-seven patients with glaucoma attending our glaucoma clinic underwent four successive intr...

journal_title：Current eye research

authors： Gaton DD,Ehrenberg M,Lusky M,Wussuki-Lior O,Dotan G,Weinberger D,Snir M

更新日期：2010-06-01 00:00:00

abstract：PURPOSE:To investigate the relationship between retinal fractal dimensions (Dfs) and retinal circulation, which is impaired in early-stage diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (DM). METHODS:Using a laser Doppler velocimetry system, we measured the retinal vessel diameter (D) and blood ve...

journal_title：Current eye research

authors： Nagaoka T,Yoshida A

更新日期：2013-11-01 00:00:00

abstract：PURPOSE:The aim of this study was to characterize a standardized porcine ex-vivo testing system for intraocular pressure (IOP) monitoring after vitrectomy with different endotamponades. METHODS:Twenty-four pig eyes, six per endotamponade group were obtained immediately postmortem. After pars plana vitrectomy, vitreous...

journal_title：Current eye research

authors： Ebner M,Mariacher S,Hurst J,Szurman P,Schnichels S,Spitzer MS,Januschowski K

更新日期：2017-08-01 00:00:00

abstract：:Two different measures of response to therapy were evaluated in a model of keratitis caused by Aspergillus fumigatus in Dutch-belted rabbits. Combined pre and post-inoculation treatment with oral fluconazole 37.5 mg/kg bid or itraconazole 40 mg/kg bid was compared to post-inoculation treatment only and untreated contr...

journal_title：Current eye research

authors： O'Day DM,Head WS,Robinson RD,Williams TE,Gedde S

更新日期：1992-01-01 00:00:00

abstract：PURPOSE:Chloride efflux plays an important role in aqueous humor production. Chloride currents have been described in bovine non-pigmented ciliary epithelium (NPE), in transformed cultured human NPE, and in bovine volume-activated chloride channels described in the latter. It is the basolateral membranes of the NPE of ...

journal_title：Current eye research

authors： Chen S,Sears M

更新日期：1997-07-01 00:00:00

abstract：PURPOSE:To investigate the roles of adherence and matrix metalloproteinases (MMPs) in growth patterns of major fungal pathogens in cornea. METHODS:Ninety-six eyes in 96 rabbits were equally divided into four groups receiving inoculation of fungal conidia of Aspergillus fumigatus, Candida albicans, Fusarium solani, and...

journal_title：Current eye research

authors： Dong X,Shi W,Zeng Q,Xie L

更新日期：2005-08-01 00:00:00

abstract：:The normal aqueous humor contains a variety of soluble immunosuppressive factors, including transforming growth factor-beta, alpha-melanocyte stimulating hormone, and vasoactive intestinal peptide. These factors are largely the secretory products of parenchymal cells of the iris and ciliary body. TGF beta has recently...

journal_title：Current eye research

authors： Streilein JW,Wilbanks GA,Taylor A,Cousins S

更新日期：1992-01-01 00:00:00

abstract：PURPOSE:The mechanism by which prostaglandin(PG)F2 alpha increases uveoscleral outflow and lowers intraocular pressure in primates is not known. In cultured human ciliary muscle cells, PGF2 alpha induces the expression of the protooncogene c-fos which is known to induce the transcription of genes such as matrix metallo...

journal_title：Current eye research

authors： Lindsey JD,Kashiwagi K,Boyle D,Kashiwagi F,Firestein GS,Weinreb RN

更新日期：1996-08-01 00:00:00

abstract：:To enhance efforts directed at unraveling the role and mechanisms of leukocytes in mediating injury to corneal epithelium, an isolated bovine corneal cup was developed and evaluated. Bovine peripheral leukocytes and lysates were added to the corneal epithelial surface of isolated cornea for various periods after which...

journal_title：Current eye research

authors： Elgebaly SA,Gillies C,Forouhar F,Hashem M,Baddour M,O'Rourke J,Kreutzer DL

更新日期：1985-01-01 00:00:00

abstract：:Langerhans cells (LC) appear to have a role in the processing of antigens presented through cutaneous surfaces. In most species LC are found in the conjunctiva and limbal epithelium but are rarely found in the central cornea. A quantitative study of corneal LC was performed in guinea pigs and rabbits with HSV-1 kerati...

journal_title：Current eye research

authors： Asbell PA,Kamenar T

更新日期：1987-01-01 00:00:00

abstract：:Purpose: The purpose of this study is to present the study design and one month's preliminary results of a 2-year randomized trial, Combined Atropine with Orthokeratology (AOK), for myopia control study. Methods: Children aged 6 to <11 years and with 1.00-4.00 D myopia were randomly assigned to AOK group or ortho-k al...

journal_title：Current eye research

authors： Tan Q,Ng AL,Cheng GP,Woo VC,Cho P

更新日期：2019-06-01 00:00:00

abstract：:It has been shown that illumination of rod outer segment suspension in the presence of photosensitizers (methylene blue lambda greater than or equal to 620 nm; retinal 370 less than or equal to lambda less than or equal to 390 nm) results in chemical modification of the lipid and protein components of the photo-recept...

journal_title：Current eye research

authors： Shvedova AA,Alekseeva OM,Kuliev IYa,Muranov KO,Kozlov YuP,Kagan VE

更新日期：1982-01-01 00:00:00

abstract：PURPOSE:To explore the roles of interleukin (IL)-17A in alkali-induced corneal neovascularization (CRNV). METHODS:Induction of CRNV by alkali injury was performed and compared in recombinant mouse IL-17A protein or anti-mouse IL-17A neutralizing antibody (Ab)-treated mice. The expression of IL-17A, IL-17A receptor (IL...

journal_title：Current eye research

authors： Liu G,Wu H,Lu P,Zhang X

更新日期：2017-03-01 00:00:00

abstract：:Utilizing a rapid colorimetric assay that relates cell number to cytoplasmic hexosaminidase activity, we conducted drug-induced cytotoxicity experiments on human ocular fibroblasts cultured from Tenon's capsule specimens. The effects of two different agents--dimethyl sulfoxide (DMSO) or mitomycin C--on the proliferati...

journal_title：Current eye research

authors： Givens KT,Lee DA,Rothschiller J,Kitada S,Larian B,Cortes A

更新日期：1990-06-01 00:00:00

abstract：PURPOSE:Most studies of cell growth of the RPE employ cultures which have been previously passaged, but here we investigated freshly-explanted RPE cells, which may have been growth-quiescent for years, within the eye to determine whether co-culture affects initial outgrowth in primary culture. METHODS:Bovine or human ...

journal_title：Current eye research

authors： McKay BS,Burke JM

更新日期：1997-09-01 00:00:00

abstract：:Purpose: Dual wavelength retinal oximetry allows the quantification of oxygen saturation in the larger retinal vessels. However, the technique might be refined further by identifying factors that are responsible for the different oxygen saturations in first order arterioles from the same eye shortly after their branch...

journal_title：Current eye research

authors： Jeppesen SK,Bek T

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:This study was designed to investigate the presence of the secretory phospholipase A2 receptor in RPE, a protein closely related to the phagocytic mannose receptor. METHODS:Proteins from cultured rat, pig, and human RPE were separated by SDS-PAGE and immunoblotted with a polyclonal guinea pig sPLA2 receptor an...

journal_title：Current eye research

authors： Wilt SD,McLaughlin BJ

更新日期：1999-07-01 00:00:00

abstract：:Intravitreal injection of purified human chorionic gonadotropin (hCG) in rabbits decreased intraocular pressure (IOP). A dose-dependent decrease in IOP was observed with intravitreal hCG concentrations at 30 nM and 100 nM. The onset of this effect was later than 10 hr following the injection and it lasted for more tha...

journal_title：Current eye research

authors： Liu JH,Dacus AC

更新日期：1988-10-01 00:00:00

abstract：:From knowledge of the optical parameters of experimental animal eyes and radiometric parameters of the light source, it is possible to provide accurate retinal irradiances (dose rates). Examples are given for the rat, cat, monkey and other animals of interest. Fluorescent lamps and incandescent lamp radiances are prov...

journal_title：Current eye research

authors： Sliney DH

更新日期：1984-01-01 00:00:00