The effect of cyclosporine in chlamydial eye infection.

abstract：:The goal of this study was to determine the effect of extracellular matrix components on the phagocytic function of the retinal pigment epithelial (RPE) cell. Cultured human fetal RPE cells were established in culture and plated on three commercially-prepared substrates: collagen IV, fibronectin and laminin and on thr...

journal_title：Current eye research

authors： Miceli MV,Newsome DA

更新日期：1996-01-01 00:00:00

abstract：PURPOSE:Previous studies have suggested that corneal fibrosis controlled by a TGFbeta-mediated cytocrine pathway underlies the development of clinical corneal haze and associated regression of photoablative effect following excimer laser PRK. Using a unique blocking antibody, we evaluated the role of TGFbeta in post-PR...

journal_title：Current eye research

authors： Møller-Pedersen T,Cavanagh HD,Petroll WM,Jester JV

更新日期：1998-07-01 00:00:00

abstract：:Thyroxine-treated human lens epithelial cells, HLE B-3, were grown in either a normoxic or hyperoxic atmosphere as a first step in identifying factors related to their increased viability. Reactive oxygen species, ROS, and the apparent mitochondrial membrane potential, Delta Psi(m), were measured using fluorescent pro...

journal_title：Current eye research

authors： Huang L,Yappert MC,Jumblatt MM,Borchman D

更新日期：2008-07-01 00:00:00

abstract：PURPOSE:To learn if peripheral nerve pathways are necessary for corneal expansion and anterior segment growth under a 12-hr light:dark cycle or for the inhibition of corneal expansion under constant light rearing. METHODS:Recently hatched White Leghorn chicks under anesthesia received unilateral ciliary ganglionectomy...

journal_title：Current eye research

authors： Stone RA,Sugimoto R,Capehart C,Pendrak K,Lin T

更新日期：2006-06-01 00:00:00

abstract：PURPOSE:Taurolidine is a broad-spectrum, non antibiotic antimicrobial agent, not previously tested against the common causes of bacterial keratitis. This study, employing an experimental rabbit model of Staphylococcus aureus keratitis, investigated the effectiveness of topical taurolidine in reducing the number of bact...

journal_title：Current eye research

authors： Oguz H,Ozbilge H,Oguz E,Gurkan T

更新日期：2005-03-01 00:00:00

abstract：PURPOSE:To evaluate the intraocular distribution and metabolism of the lipid prodrug of foscarnet, 1-O-octadecyl-sn-glycerol-3- phosphonoformate (ODG-PFA), following intravitreal administration. METHODS:Twenty rabbits received ODG-[14C]PFA intravitreal injection, yielding 0.632 mM resultant intravitreal concentration....

journal_title：Current eye research

authors： Cheng L,Hostetler KY,Gardner MF,Avila CP Jr,Bergeron-Lynn G,Severson GM,Freeman WR

更新日期：1999-03-01 00:00:00

abstract：PURPOSE:To assess the incidence of cell proliferation and apoptosis in epiretinal membranes from eyes with proliferative vitreoretinopathy (PVR), proliferative diabetic retinopathy (PDR), and macular pucker (MP) and to further investigate the potential involvement of key executors of apoptosis. METHODS:Epiretinal memb...

journal_title：Current eye research

authors： Zhang X,Barile G,Chang S,Hays A,Pachydaki S,Schiff W,Sparrow J

更新日期：2005-05-01 00:00:00

abstract：PURPOSE:Nuclear factor-kappa B (NF-κB) has been proposed as a therapeutic target for the treatment of cataracts. The authors investigated the relationship between nuclear factor of activated T cells 5 (NFAT5) and NF-κB in ultraviolet B (UVB)-irradiated human lens epithelial (HLE) cells. METHODS:Human lens epithelial B...

journal_title：Current eye research

authors： Chung I,Hah YS,Ju S,Kim JH,Yoo WS,Cho HY,Yoo JM,Seo SW,Choi WS,Kim SJ

更新日期：2017-07-01 00:00:00

abstract：:Purpose: To evaluate the effect of isolated oblique muscle weakening on horizontal deviation in patients with A- and V-pattern exotropia.Methods: The medical records of patients who underwent bilateral oblique muscle weakening for A- and V-pattern exotropia associated oblique muscle overaction between 2011 and 2018 we...

journal_title：Current eye research

authors： Wang X,Zhang W,Liu L

更新日期：2020-02-01 00:00:00

abstract：PURPOSE:The aim of this study was to examine the functional connectivity between the primary visual cortex and other cortical areas during rest in normal subjects and patients with comitant strabismus using functional magnetic resonance imaging (fMRI). METHODS:A prospective, observational study was conducted. Ten pati...

journal_title：Current eye research

authors： Yan X,Wang Y,Xu L,Liu Y,Song S,Ding K,Zhou Y,Jiang T,Lin X

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:To investigate the roles of adherence and matrix metalloproteinases (MMPs) in growth patterns of major fungal pathogens in cornea. METHODS:Ninety-six eyes in 96 rabbits were equally divided into four groups receiving inoculation of fungal conidia of Aspergillus fumigatus, Candida albicans, Fusarium solani, and...

journal_title：Current eye research

authors： Dong X,Shi W,Zeng Q,Xie L

更新日期：2005-08-01 00:00:00

abstract：PURPOSE:We compared the hand-guided Moria Carriazo-Barraquer (CBm) microkeratome with the fully automatic SLc microkeratome for Descemet's stripping automated endothelial keratoplasty (DSAEK)-lamella preparation and storage, vis-à-vis accuracy, endothelial cell loss (ECL), and lamellar surface roughness (LSR). METHODS...

journal_title：Current eye research

authors： Fuest M,Salla S,Walter P,Plange N,Kuerten D,Flammersfeld A,Hermel M

更新日期：2016-01-01 00:00:00

abstract：:The variation of central corneal thickness with age was measured weekly at 10am by ultrasound pachometry in 10 normal (5 to 19 weeks of age) and 10 alloxan-induced diabetic (9 to 19 weeks of age) rabbits. The diurnal variation of corneal thickness was also measured at 2 hour intervals for a period of 24 hours on both ...

journal_title：Current eye research

authors： Herse PR

更新日期：1990-05-01 00:00:00

abstract：:Goggles that degrade the retinal image produce axial enlargement of the ocular globe and large myopic refractive errors. Many authors have assumed that visual image degradation itself leads to myopia. Hodos and co-authors have shown, however, that goggled eyes in chicks are considerably warmer than normal. Such temper...

journal_title：Current eye research

authors： Shih YF,Fitzgerald ME,Norton TT,Gamlin PD,Hodos W,Reiner A

更新日期：1993-03-01 00:00:00

abstract：PURPOSE:To examine the efficacy of oral doxycycline treatment (as compared to oral and topical dexamethasone) for inhibiting corneal neovascularization (CNV). METHODS:Following corneal alkali burn, rats were treated daily with oral doxycycline, oral dexamethasone, or topical dexamethasone for 14 days. Control rats wer...

journal_title：Current eye research

authors： Dan L,Shi-long Y,Miao-li L,Yong-ping L,Hong-jie M,Ying Z,Xiang-gui W

更新日期：2008-08-01 00:00:00

abstract：PURPOSE:To determine the cellular mechanisms involved in the hypoxia-induced alteration of the retinal pigment epithelium (RPE) potentials and the light-evoked responses of the RPE in chicks. In addition, to determine the mechanisms involved in the recovery of the RPE during the post-hypoxic period. METHODS:In vitro p...

journal_title：Current eye research

authors： Nakazaki S,Nao-i N,Sawada A

更新日期：1998-04-01 00:00:00

abstract：:The intraocular inflammatory reaction in a murine model of herpes simplex keratouveitis was studied using immunohistochemical techniques. 5 x 10(5) PFU of HSV-1 (Stewart strain) was applied to the abraded cornea of BALB/c mice. The subsequent development of keratouveitis was documented by sequential examination, conve...

journal_title：Current eye research

authors： Wang HM,Sheu MM,Stulting RD,Kaplan HJ

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Interleukin-6 (IL-6) is produced by a variety of cells involved in inflammation and acts as local intensification signals in pathological processes associated with chronic eye inflammation. This meta-analysis was performed to provide a better understanding of the relationship between IL-6 and diabetic retino...

journal_title：Current eye research

authors： Yao Y,Li R,Du J,Long L,Li X,Luo N

更新日期：2019-05-01 00:00:00

abstract：PURPOSE:Histidine is an indispensable amino acid with an imidazole ring and it is a precursor of histamine, carnosine, and anserine. Histidine has been proposed to act as a neurotransmitter or neuromodulator in mammalian central nervous system (CNS), including retina. In this study, we report histidine-like immunoreact...

journal_title：Current eye research

authors： Kusakari Y,Nishikawa S,Ishiguro S,Tamai M

更新日期：1997-06-01 00:00:00

abstract：:Intracellular binding proteins have been identified and isolated from B cells by their ability to bind to the synthetic peptide (1169-1191), the major immunodominant epitope of bovine interphotoreceptor retinoid-binding protein (IRBP) coupled to cyanogen bromide activated Sepharose 4B. After SDS-PAGE, two discrete pro...

journal_title：Current eye research

authors： Rengarajan K,de Smet MD,Chader GJ,Wiggert B

更新日期：1994-04-01 00:00:00

abstract：PURPOSE:Previous studies revealed an association of tumor necrosis factor super family-15 (TNFSF15) gene polymorphisms with several autoimmune diseases, but their roles in the development of Graves' disease (GD) and Graves' ophthalmopathy (GO) remain unclear. The aim of this study was to explore the correlation between...

journal_title：Current eye research

authors： Zhang M,Liu S,Xu J,Lv S,Fan Y,Zhang Y,Zhang Y,Wu Y,Su Y,Yu H,Song S,He J,Li H

更新日期：2020-07-01 00:00:00

abstract：PURPOSE:To evaluate differences of phagocytic capacities in rat retinal pigment epithelial (RPE) cells, iris pigment epithelial (IPE) cells, and basic fibroblast growth factor (bFGF) cDNA-transfected IPE (bFGF-IPE) cells in vitro. METHODS:The RPE cells and IPE cells were isolated from adult Long Evans rats' eyes. The ...

journal_title：Current eye research

authors： Sakuragi M,Tomita H,Abe T,Tamai M

更新日期：2001-09-01 00:00:00

abstract：:Corneas and tendons dissected from 17-day-old chick embryos were labeled with [35S]methionine in the presence of 0.3 mM alpha,alpha'-dipyridyl. The unhydroxylated, 35S-labeled pro alpha chains and alpha chains were isolated by polyacrylamide gel electrophoresis in sodium dodecyl sulfate. The pro alpha and alpha chains...

journal_title：Current eye research

authors： Kao WW

更新日期：1985-02-01 00:00:00

abstract：PURPOSE:Retinoblastoma (RB) is the most common intraocular malignancy in children. Deregulation of several miRNAs has been identified in RB, suggesting a potential role in tumorigenesis. Recent evidence suggests that many dietary components like folate, retinoids and curcumin act as potential anticancer/antiproliferati...

journal_title：Current eye research

authors： Sreenivasan S,Thirumalai K,Danda R,Krishnakumar S

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:To compare the antiviral effect of a peptide derived from human apolipoprotein E (1% apoEdp) with 1% trifluorothymidine against HSV-1 thymidine kinase (TK)-positive (HSV-1 McKrae) and with 3% foscarnet against HSV-1 TK-negative (KOS background) in the rabbit eye model of acute HSV-1 epithelial keratitis. MATER...

journal_title：Current eye research

authors： Bhattacharjee PS,Neumann DM,Hill JM

更新日期：2009-02-01 00:00:00

abstract：PURPOSE:There is limited information on region-specific gene expression in the human corneal stroma. In this study, we aimed to investigate the expression profile of the extracellular matrix and adhesion molecules in the normal corneal stroma using laser capture microdissection (LCM) and molecular techniques. METHODS:...

journal_title：Current eye research

authors： Liu Y,Huang H,Sun G,Alwadani S,Semba RD,Lutty GA,Yiu S,Edward DP

更新日期：2017-04-01 00:00:00

abstract：:In the unsutured partial thickness penetrating wounds of the cornea, the epithelium migrates over the wounded stromal surface prior to the onset of stromal regeneration. To determine the possible affects of the epithelial ingrowth on the organization of the stromal scar tissues, the healing of unsutured and sutured wo...

journal_title：Current eye research

authors： Melles GR,SundarRaj N,Binder PS,van der Weiden MM,Wijdh RH,Beekhuis WH,Anderson JA

更新日期：1995-09-01 00:00:00

abstract：:Blood and lymphatic vessel proliferation into the cornea occurs after severe trauma. Whilst the events early in blood vessel growth are reasonably understood, little is known of the early events in lymphangiogenesis. In this study, a model for proliferating lymphatic vessels using tritiated-thymidine autoradiography a...

journal_title：Current eye research

authors： Junghans BM,Collin HB

更新日期：1989-01-01 00:00:00

abstract：PURPOSE:To evaluate the length of the trabecular meshwork (TM) from the scleral spur (SS) to Schwalbe's line (SL) and assess the detectability of the SS in histopathology specimens. METHODS:This study included 158 angle images from 79 cross-sectional slides derived from eyes enucleated for melanoma. The slides were st...

journal_title：Current eye research

authors： Kasuga T,Chen YC,Bloomer MM,Hirabayashi KE,Hiratsuka Y,Murakami A,Lin SC

更新日期：2013-01-01 00:00:00

abstract：PURPOSE OF THE STUDY:To assess differences in healthy eyes in volume (CV) and choroidal thicknesses (CT) across all macular Early Treatment Diabetic Retinopathy Study (ETDRS) areas measured by swept source (SS)-OCT and spectral domain (SD)-OCT with enhanced depth imaging (EDI). MATERIALS AND METHODS:One hundred and fi...

journal_title：Current eye research

authors： Pinilla I,Sanchez-Cano A,Insa G,Bartolomé I,Perdices L,Orduna-Hospital E

更新日期：2021-02-01 00:00:00