The effect of topical retinoic acid (Etretinate) on mouse conjunctival Langerhans cells.

abstract：:The initial rapid fall in tear film fluorescence after instilling a 1 microliter drop of fluorophore could be a result of stimulated tear flow or of distribution of the dye throughout the tear fluid present in the conjunctival sac. An attempt was made to decide this by comparing the fall in fluorescence of two differe...

journal_title：Current eye research

authors： Sang NM,Maurice DM

更新日期：1995-04-01 00:00:00

abstract：:An experimental model of optic nerve ischemia was designed in the rabbit to determine early biochemical alterations, i.e.--changes of high energy phosphate metabolites (ATP and phosphocreatine)--in occlusive and peri-occlusive areas. Vascular occlusion provoked a rapid fall of ATP and phosphocreatine in the optic nerv...

journal_title：Current eye research

authors： Vériac S,Tissié G,Bonne C

更新日期：1992-03-01 00:00:00

abstract：PURPOSE:To examine the association between macular pigment optical density (MPOD) and rod-mediated dark adaptation (RMDA) in persons ≥60 years old with normal maculas as determined by an accepted color fundus photography grading system. METHODS:This cross-sectional analysis used baseline data from eyes in the Alabama ...

journal_title：Current eye research

authors： Zarubina AV,Huisingh CE,Clark ME,Sloan KR,McGwin G Jr,Crosson JN,Curcio CA,Owsley C

更新日期：2018-07-01 00:00:00

abstract：PURPOSE:Diabetic maculopathy (DM) treated with photocoagulation may subsequently progress to proliferative diabetic retinopathy (PDR). However, there is insufficient knowledge about the incidence and risk factors for the development of PDR in patients previously treated for DM. MATERIALS AND METHODS:Survival data was ...

journal_title：Current eye research

authors： Bek T

更新日期：2020-08-01 00:00:00

abstract：PURPOSE:To evaluate the immediate effect of 3% diquafosol ophthalmic solution on tear MUC5AC concentration, periodic acid-Schiff (PAS)-positive goblet cells, and tear film stability in normal and keratoconjunctivitis sicca (KCS) rat models. METHODS:Rats were divided into normal and KCS groups. 3% of diquafosol solutio...

journal_title：Current eye research

authors： Choi KE,Song JS,Kang B,Eom Y,Kim HM

更新日期：2017-05-01 00:00:00

abstract：PURPOSE:To evaluate how patient satisfaction after cataract surgery is associated with postoperative visual acuity, visual functioning, dry eye signs and symptoms, health anxiety, and depressive symptoms. PATIENTS AND METHODS:Fifty-four patients (mean age: 68.02 years) were assessed 2 months after uneventful phacoemul...

journal_title：Current eye research

authors： Szakáts I,Sebestyén M,Tóth É,Purebl G

更新日期：2017-06-01 00:00:00

abstract：:Levels of rhodopsin in the photoreceptors of Long-Evans rats were reduced by approximately 55% through dietary deprivation of vitamin A. The interaction of visual pigment with G-protein was examined in receptor outer segment (ROS) membranes obtained from these animals. A binding assay was used to quantitate affinity o...

journal_title：Current eye research

authors： Pepperberg DR,Anderson SM,Crouch R

更新日期：1989-04-01 00:00:00

abstract：PURPOSE:Nona-D-arginine amide (D9R) affected a cure of Pseudomonas aeruginosa corneal disease when combined with ciprofloxacin. In this study, we show that D9R alone and prophylactic treatment with D9R significantly reduced corneal pathology and bacterial burden associated with P. aeruginosa infection. MATERIALS AND M...

journal_title：Current eye research

authors： Karicherla P,Hobden JA

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:To assess the potential impact of corneal crosslinking treatment (365 nm ultraviolet (UV)A irradiation with riboflavin) on the material properties of Intracorneal Rings Segments (ICRS). MATERIALS AND METHODS:Material properties were studied using FT-IR spectroscopy and UV-Vis spectroscopy. Rings were examined:...

journal_title：Current eye research

authors： Sideroudi H,Labiris G,Soto-Beobide A,Voyiatzis G,Chrissanthopoulos A,Kozobolis V

更新日期：2015-05-01 00:00:00

abstract：:The aim of this study was to determine whether or not alpha neoprotein formation can occur in the lens in response to a photolytic process. Alpha crystallin from young calf and aged bovine lenses was irradiated for up to 22 hours with UV light. After cortical alpha crystallin had been irradiated, it completely preserv...

journal_title：Current eye research

authors： Hibino K,Du J,Dillon J,Malinowski K

更新日期：1988-11-01 00:00:00

abstract：PURPOSE:To compare the clinical outcomes following Descemet's membrane endothelial keratoplasty (DMEK) with 100% air tamponade versus 10% sulfur hexafluoride (SF6) tamponade. METHODS:Retrospective analysis of 108 consecutive DMEK cases subdivided by anterior chamber tamponade with 54 eyes receiving 10% SF6 and 54 eyes...

journal_title：Current eye research

authors： Rickmann A,Szurman P,Jung S,Boden KT,Wahl S,Haus A,Boden K,Januschowski K

更新日期：2018-04-01 00:00:00

abstract：:Membrane response to the various temperatures as one of the external factors was investigated in the lenses of the poikilothermal animal and the homothermal animal. The rainbow trout lens was used as the poikilothermal material and the rat lens as the homothermal material. The rainbow trout lens maintained in vitro it...

journal_title：Current eye research

authors： Iwata S

更新日期：1985-04-01 00:00:00

abstract：:To investigate the role of lymphocytes in the pathogenesis of uveitis, we analyzed the expression of memory markers, CD29 and CD45RO antigens, and apoptosis-related Fas antigen on T lymphocytes in the aqueous humor (AH) and peripheral blood (PB) from patients with uveitis. Using three-color flow cytometry, we assessed...

journal_title：Current eye research

authors： Ohta K,Norose K,Wang XC,Ito S,Yano A,Segawa K

更新日期：1996-03-01 00:00:00

abstract：PURPOSE:Increases in matrix proteins, such as type I collagen and fibronectin, are observed with aging in the retinal pigment epithelium (RPE) basement membrane. However, little is known about altered gene expression profiles of RPE associated with increases in matrix proteins. We investigated changes in gene expressio...

journal_title：Current eye research

authors： Imai H,Honda S,Kondo N,Ishibashi K,Tsukahara Y,Negi A

更新日期：2007-10-01 00:00:00

abstract：PURPOSE:To evaluate the effect of short-term hypobaric hypoxic conditions (STHC) on intraocular pressure (IOP) in healthy subjects. METHODS:The study group was comprised of 30 healthy participants (60 eyes) with a mean age of 24.8 years. IOP was measured with a Tono-Pen XL tonometer at ground level (792 m above sea le...

journal_title：Current eye research

authors： Karadag R,Sen A,Golemez H,Basmak H,Yildirim N,Karadurmus N,Koseoglu E,Akin A

更新日期：2008-10-01 00:00:00

abstract：:Purpose: To determine the refractive astigmatism following toric intraocular lens (tIOL) implantation without consideration of posterior keratometric astigmatism with a conventional tIOL calculator for eyes with low keratometric astigmatism (0.75D to 2.5D) and to theoretically compare the outcomes with predicted refra...

journal_title：Current eye research

authors： Nanavaty MA,Teeluck K,Bardan AS,Bedi KK,Ali S

更新日期：2019-12-01 00:00:00

abstract：:Intravitreal injection of purified human chorionic gonadotropin (hCG) in rabbits decreased intraocular pressure (IOP). A dose-dependent decrease in IOP was observed with intravitreal hCG concentrations at 30 nM and 100 nM. The onset of this effect was later than 10 hr following the injection and it lasted for more tha...

journal_title：Current eye research

authors： Liu JH,Dacus AC

更新日期：1988-10-01 00:00:00

abstract：PURPOSE:To evaluate postnatal developmental changes in the amounts of retinal glutamate, glutamine and GABA, and in the distribution of retinal glutamine in the rat. METHODS:Free amino acids were extracted from rat retinas of different postnatal stages, and the concentrations of glutamate, glutamine and GABA were dete...

journal_title：Current eye research

authors： Ishikawa A,Shiono T,Ishiguro S,Tamai M

更新日期：1996-06-01 00:00:00

abstract：:Using experimental model of uveitis, the inflammation-associated chemiluminescence was measured by luminol amplification method. The induction of uveitis in Lewis rats was carried out by immunizing bovine S-antigen in complete Freund's adjuvant on hind foot-pad. The chemiluminescence activity from six sets of retina a...

journal_title：Current eye research

authors： Wu GS,Goto H,Sevanian A,Rao NA

更新日期：1991-10-01 00:00:00

abstract：:Recently, all the structural features of non-proliferative diabetic retinopathy have been demonstrated in mice fed 30% galactose for 21-26 months. To determine whether changes in retinal matrix protein mRNA levels occur early in the course of murine diabetes we used a competitive RT-PCR method to quantitate retinal mR...

journal_title：Current eye research

authors： Nishikawa T,Giardino I,Edelstein D,Brownlee M

更新日期：2000-07-01 00:00:00

abstract：:Previous attempts to prepare monoclonal antibodies (MAbs) against S-antigen, a photoreceptor cell protein involved in the visual process and a potent autoantigen for the induction of experimental autoimmune uveitis (EAU), have yielded MAbs which define only carboxyl terminal epitopes. In this study we devised alternat...

journal_title：Current eye research

authors： Donoso LA,Gregerson DS,Smith L,Robertson S,Knospe V,Vrabec T,Kalsow CM

更新日期：1990-04-01 00:00:00

abstract：PURPOSE:Form-deprivation myopia (FDM) is believed to result principally from actions of substances that modulate information processing in the retina. We used a chick model to investigate what role nitric oxide (NO), a gaseous neuromodulator, might play in the development of FDM. METHODS:We injected different concentr...

journal_title：Current eye research

authors： Fujikado T,Kawasaki Y,Fujii J,Taniguchi N,Okada M,Suzuki A,Ohmi G,Tano Y

更新日期：1997-10-01 00:00:00

abstract：:Many tissues which require vitamin A store the vitamin as long-chain fatty acyl esters of retinol. As part of a study designed to characterize vitamin A metabolism in the lacrimal gland, which transports retinol from blood to lacrimal gland fluid, extracts from lacrimal glands of rabbits and rats were analyzed by non-...

journal_title：Current eye research

authors： Ubels JL,Osgood TB,Foley KM

更新日期：1988-10-01 00:00:00

abstract：PURPOSE:To assess the morphology of superficial bulbar conjunctival cells collected by impression cytology or by scraping. METHODS:Freshly procured sheep eyes from a slaughterhouse were washed and then conjunctival impression cytology (CIC) samples taken from the nasal aspect of the bulbar conjunctiva on a Biopore Mil...

journal_title：Current eye research

authors： Doughty MJ

更新日期：2014-10-01 00:00:00

abstract：PURPOSE:To examine whether transforming growth factor-beta 2 (TGF-beta 2) induces the expression of alpha-smooth muscle actin (SMA), a biochemical marker of myofibroblasts, in cultured bovine retinal pigment epithelial (RPE) cells. METHODS:Bovine RPE cells were cultured in F-12 nutrient mixture supplemented with 5% fe...

journal_title：Current eye research

authors： Kurosaka D,Muraki Y,Inoue M,Katsura H

更新日期：1996-11-01 00:00:00

abstract：PURPOSE:Statins have been shown to reduce ocular inflammation in animal models of uveitis and to prevent development of uveitis in observational studies. There have been no experimental human studies evaluating statins' efficacy and safety in uveitis. In this study, we aimed to investigate efficacy and safety of simvas...

journal_title：Current eye research

authors： Shirinsky IV,Biryukova AA,Shirinsky VS

更新日期：2017-12-01 00:00:00

abstract：:Rainbow trout (Oncorhynchus mykiss) were used to model the solar radiation-induced cataract that occurs in hatchery-reared lake trout (Salvelinus namaycush). Rainbow trout eyes were exposed to wideband predominantly UVB radiant energy from a filtered 1000W xenon source. Lenticular damage was assessed and classified an...

journal_title：Current eye research

authors： Cullen AP,Monteith-McMaster CA

更新日期：1993-02-01 00:00:00

abstract：PURPOSE:Corneal autofluorescence is related to advanced glycation end products formed by glucose that reaches the cornea via the aqueous humour. The aim of the study was to examine the influence on autofluorescence of changes in permeability of the blood aqueous barrier. METHODS:Corneal autofluorescence was measured i...

journal_title：Current eye research

authors： Kessel L,Moldow B,van Best JA,Sander B

更新日期：2003-05-01 00:00:00

abstract：:We studied the effects of a forskolin suspension on intraocular pressure (IOP) in normal albino and pigmented rabbits and in alpha-chymotrypsin induced ocular hypertensive rabbits. Experimental-induced ocular hypertensive rabbits were produced by injecting of alpha-chymotrypsin (167 units) into the posterior chamber o...

journal_title：Current eye research

authors： Shibata T,Mishima H,Kurokawa T

更新日期：1988-07-01 00:00:00

abstract：PURPOSE:To determine the relative expression of metallothionein isoforms and their differential induction by oxidative stress in cultured RPE cells and to localize the isoforms in the human chorioretinal complex. METHODS:Total RNA was isolated from cultured human retinal pigment epithelial cells using TRI-Reagent. An ...

journal_title：Current eye research

authors： Tate DJ,Miceli MV,Newsome DA

更新日期：2002-01-01 00:00:00