Activity of rhodopsin in vitamin A-deprived rats: light-dependent binding of G-protein.

abstract：PURPOSE:To investigate orbital biomechanical properties in patients with thyroid orbitopathy and in age- and gender-matched healthy subjects using the Corvis-ST (CST, Oculus Wetzlar, Germany). METHODS:The CST allows a non-contact tonometry with an ultra-high-speed Scheimpflug device to record the deformation of the co...

journal_title：Current eye research

authors： Leszczynska A,Moehler K,Spoerl E,Ramm L,Herber R,Pillunat LE,Terai N

更新日期：2018-03-01 00:00:00

abstract：:The mechanism of oxidative damage to the lens through intraocular photochemical generation of superoxide and its derivatization to other oxidants such as singlet oxygen, hydroxyl radical and hydrogen peroxide has been studied. Rat lenses when organ cultured aerobically in TC 199 containing additional amounts of ribofl...

journal_title：Current eye research

authors： Varma SD,Chand D,Sharma YR,Kuck JF Jr,Richards RD

更新日期：1984-01-01 00:00:00

abstract：PURPOSE:Recent studies have shown that the levels of interleukin (IL)-1beta, IL-6 and IL-8 are associated with the severity of infectious diseases. The purpose of this study was to investigate whether IL-1beta regulates the expression of IL-6 and IL-8 in human corneal epithelial cells during Pseudomonas aeruginosa colo...

journal_title：Current eye research

authors： Xue ML,Zhu H,Willcox M,Wakefield D,Lloyd A,Thakur A

更新日期：2001-12-01 00:00:00

abstract：PURPOSE:There is a substantial literature showing that the selective estrogen receptor modulator tamoxifen can block swelling-activated chloride channels, such as those in astrocytes. This study aimed to test the hypothesis that anatomic characteristics consistent with swelling may be measured within the optic nerve he...

journal_title：Current eye research

authors： Eisner A,O'Malley JP,Incognito LJ,Toomey MD,Samples JR

更新日期：2006-04-01 00:00:00

abstract：:The efficiency of protein immobilization to provide a hydrogel surface with a high affinity for corneal epithelial cells was investigated. The cell adhesive proteins collagen and fibronectin, and the cell adhesive oligopeptide RGDS (arginine-glycine-aspartic acid-serine) were successfully covalently immobilized on pol...

journal_title：Current eye research

authors： Kobayashi H,Ikada Y

更新日期：1991-10-01 00:00:00

abstract：PURPOSE:To evaluate the effect of the birth weight and the postconceptional age on the tear production of preterm and term newborn infants and to evaluate the changes in tear production during the first two months of life. SUBJECTS--METHODS: Both eyes of medically stable term and preterm infants were included in the st...

journal_title：Current eye research

authors： Akar Y,Cira A,Apaydin C,Erman MA,Yilmaz A

更新日期：2004-02-01 00:00:00

abstract：PURPOSE:To evaluate how patient satisfaction after cataract surgery is associated with postoperative visual acuity, visual functioning, dry eye signs and symptoms, health anxiety, and depressive symptoms. PATIENTS AND METHODS:Fifty-four patients (mean age: 68.02 years) were assessed 2 months after uneventful phacoemul...

journal_title：Current eye research

authors： Szakáts I,Sebestyén M,Tóth É,Purebl G

更新日期：2017-06-01 00:00:00

abstract：:Lacrimal gland fluid is an important component of the precorneal tear film. The rate of lacrimal gland fluid secretion is controlled primarily by parasympathetic innervation, and it is, apparently, modulated by sympathetic innervation. Lacrimal gland fluid is produced in two stages, secretion of a primary fluid which ...

journal_title：Current eye research

authors： Mircheff AK

更新日期：1989-06-01 00:00:00

abstract：PURPOSES:To investigate whether valproic acid (VPA) has a neuroprotective effect against ischemia/reperfusion (I/R) injury in the rat retina, and to elucidate the potential antioxidant mechanisms involved. METHODS:Adult male Wistar rats were randomly divided into four groups: sham (group A), sham plus VPA (group B), I...

journal_title：Current eye research

authors： Zhang Z,Qin X,Zhao X,Tong N,Gong Y,Zhang W,Wu X

更新日期：2012-05-01 00:00:00

abstract：AIM:To compare patient satisfaction and experience after external dacryocystorhinostomy (EX-DCR) versus transcanalicular DCR (TC-DCR) with a diode laser and to evaluate the change in quality of life following simultaneous bilateral DCR. METHODS:Prospective evaluation of 38 eyes of 19 patients with bilateral nasolacrim...

journal_title：Current eye research

authors： Yeniad B,Uludag G,Kozer-Bilgin L

更新日期：2012-04-01 00:00:00

abstract：PURPOSE:Methotrexate (MTX) is the most commonly used chemotherapeutic agent to treat primary central nervous system lymphoma (PCNSL) and intraocular lymphoma (IOL). 2-methoxyestradiol (2ME2) is a potent antitumor and anti-angiogenesis agent which, unlike other cytotoxic drugs, has minimal toxicity. In this study, anti-...

journal_title：Current eye research

authors： Park J,Franco RS,Augsburger JJ,Banerjee RK

更新日期：2007-07-01 00:00:00

abstract：:In the unsutured partial thickness penetrating wounds of the cornea, the epithelium migrates over the wounded stromal surface prior to the onset of stromal regeneration. To determine the possible affects of the epithelial ingrowth on the organization of the stromal scar tissues, the healing of unsutured and sutured wo...

journal_title：Current eye research

authors： Melles GR,SundarRaj N,Binder PS,van der Weiden MM,Wijdh RH,Beekhuis WH,Anderson JA

更新日期：1995-09-01 00:00:00

abstract：:The initial rapid fall in tear film fluorescence after instilling a 1 microliter drop of fluorophore could be a result of stimulated tear flow or of distribution of the dye throughout the tear fluid present in the conjunctival sac. An attempt was made to decide this by comparing the fall in fluorescence of two differe...

journal_title：Current eye research

authors： Sang NM,Maurice DM

更新日期：1995-04-01 00:00:00

abstract：PURPOSE:The aim of the present study was to calculate the diameter of the central retinal artery from results as obtained with non-invasive techniques in healthy young subjects. METHODS:Twenty-four healthy male subjects participated in this study. Total retinal blood flow was calculated from combined bi-directional la...

journal_title：Current eye research

authors： Dorner GT,Polska E,Garhöfer G,Zawinka C,Frank B,Schmetterer L

更新日期：2002-12-01 00:00:00

abstract：:In an attempt to determine the factors involved in ocular pigment variation, the eyes of pallid mice (c57BL/6J-Pa/Pa), and those of littermate black mice (C57BL/6J-+/Pa) were examined ultrastructurally, histochemically, and biochemically. As controls, the eyes of black and congenic albino mice (C57BL/6J +/C2J and -C2J...

journal_title：Current eye research

authors： Ito M,Hashimoto K,Organisciak DT

更新日期：1982-01-01 00:00:00

abstract：PURPOSE:Diabetic maculopathy (DM) treated with photocoagulation may subsequently progress to proliferative diabetic retinopathy (PDR). However, there is insufficient knowledge about the incidence and risk factors for the development of PDR in patients previously treated for DM. MATERIALS AND METHODS:Survival data was ...

journal_title：Current eye research

authors： Bek T

更新日期：2020-08-01 00:00:00

abstract：PURPOSE:Intrastromal epithelial migration occurs following deep excimer annular keratectomy. Our purpose is to determine the localization of gelatinase B expression and its relationship to migrating intrastromal epithelial cells following deep annular excimer keratectomy. METHODS:Rabbit corneas were treated with deep ...

journal_title：Current eye research

authors： Maeda M,Vanlandingham BD,Ye H,Lu PC,Azar DT

更新日期：1998-08-01 00:00:00

abstract：PURPOSE:To investigate the morphological or functional differences of retina in amblyopia. MATERIALS AND METHODS:Forty-one patients with unilateral strabismic, anisometropic or combined amblyopia were included in the study. A control group was composed of 16 normal children. All participants were tested with optical c...

journal_title：Current eye research

authors： Tugcu B,Araz-Ersan B,Kilic M,Erdogan ET,Yigit U,Karamursel S

更新日期：2013-07-01 00:00:00

abstract：PURPOSE:In the limbo-corneal epithelium the stem and early precursor epithelial cell pool is confined to the limbal rim. Among the features associated with this spatial segregation is the general paucity of connexin43 (Cx43) within the limbal basal cell population and its complete absence in resident stem cells. The li...

journal_title：Current eye research

authors： Wolosin JM,Schütte M,Zieske JD,Budak MT

更新日期：2002-06-01 00:00:00

abstract：PURPOSE:To investigate the association of nailfold capillaroscopy, heart rate variability (HRV), and clinical characteristics of glaucoma with the plasma matrix metalloproteinase-9 (MMP-9) level in normal-tension glaucoma (NTG). MATERIALS AND METHODS:We conducted a prospective, cross-sectional study on 25 patients wit...

journal_title：Current eye research

authors： Lee NY,Park HY,Park SH,Park CK

更新日期：2015-01-01 00:00:00

abstract：:The goal of this study was to determine the effect of extracellular matrix components on the phagocytic function of the retinal pigment epithelial (RPE) cell. Cultured human fetal RPE cells were established in culture and plated on three commercially-prepared substrates: collagen IV, fibronectin and laminin and on thr...

journal_title：Current eye research

authors： Miceli MV,Newsome DA

更新日期：1996-01-01 00:00:00

abstract：:The short and long term response of the trabecular meshwork to a phagocytic challenge and the response of the meshwork to different types of foreign particles was studied by injecting one eye of 25 adult cats with a phagocytic agent (zymosan, blood, or latex microspheres) while the fellow eye received a control soluti...

journal_title：Current eye research

authors： Johnson DH,Richardson TM,Epstein DL

更新日期：1989-11-01 00:00:00

abstract：:Severe retinopathy of prematurity (ROP) occurs in the smallest and sickest of premature infants. We hypothesized that, in a rat model of oxygen induced retinopathy, abnormal neovascularization would occur more frequently in larger litters where the pups are subject to postnatal growth retardation. Four litters of newb...

journal_title：Current eye research

authors： Holmes JM,Duffner LA

更新日期：1996-04-01 00:00:00

abstract：:Introduction: Metabolic syndrome is a disorder characterized by a constellation of findings including truncal obesity, elevated blood pressure, abnormal cholesterol levels, and high blood glucose. Recent evidence suggests that metabolic syndrome may be associated with increased risk of age-related macular degeneration...

journal_title：Current eye research

authors： Roddy GW,Rosa RH,Viker KB,Holman BH,Hann CR,Krishnan A,Gores GJ,Bakri SJ,Fautsch MP

更新日期：2020-06-01 00:00:00

abstract：PURPOSE:To characterize the possible cytotoxic effects of oxysterols (7beta-hydroxycholesterol (7beta-OH), 25-hydroxycholesterol (25-OH)) in human retinal pigment epithelial cells (ARPE-19) and to detail the relationships between some of these effects. METHODS:ARPE-19 cells were treated with 7beta-OH and 25-OH. Cell v...

journal_title：Current eye research

authors： Malvitte L,Montange T,Vejux A,Joffre C,Bron A,Creuzot-Garcher C,Lizard G

更新日期：2008-09-01 00:00:00

abstract：:EDGF, a growth factor purified from bovine retina is able to increase the rate of wound healing of rabbit corneal epithelium in a dose dependent way. Two applications a day are enough to obtain the maximum rate. The most purified preparation of EDGF is as effective as EGF or pFGF in promoting this phenomenon and allow...

journal_title：Current eye research

authors： Petroutsos G,Courty J,Guimaraes R,Pouliquen Y,Barritault D,Plouët J,Courtois Y

更新日期：1984-04-01 00:00:00

abstract：:Corneal acidosis has been shown to reduce corneal hydration control (CHC) as measured by the rate, expressed as the percent recovery per hour (PRPH), at which the thickness of the cornea decreases exponentially after an increased hydration load. Since the effect of pH on corneal function is of scientific interest and ...

journal_title：Current eye research

authors： Cohen SR,Polse KA,Brand RJ,Bonanno JA

更新日期：1995-05-01 00:00:00

abstract：:Penetrating keratoplasty was the only therapeutic choice for the treatment of corneal endothelial decompensation until the introduction of evolutional endothelial keratoplasties, namely Descemet's stripping automated endothelial keratoplasty (DSAEK) and Descemet's membrane endothelial keratoplasty (DMEK). Although now...

journal_title：Current eye research

authors： Okumura N,Koizumi N

更新日期：2020-03-01 00:00:00

abstract：:Intracellular binding proteins have been identified and isolated from B cells by their ability to bind to the synthetic peptide (1169-1191), the major immunodominant epitope of bovine interphotoreceptor retinoid-binding protein (IRBP) coupled to cyanogen bromide activated Sepharose 4B. After SDS-PAGE, two discrete pro...

journal_title：Current eye research

authors： Rengarajan K,de Smet MD,Chader GJ,Wiggert B

更新日期：1994-04-01 00:00:00

abstract：PURPOSE:To evaluate "in vivo" the effect of topical travoprost on the central corneal thickness (CCT) of rabbit eyes, and the changes in the CCT after acute increases of intraocular pressure (IOP) in these eyes. MATERIALS AND METHODS:This is an interventional, prospective, case-control, masked study. Topical travopros...

journal_title：Current eye research

authors： Bolívar G,Teus M,Arranz-Marquez E

更新日期：2011-11-01 00:00:00