The combined effect of diabetes and ionising radiation on the retinal vasculature of the rat.

abstract：:The water soluble (WS), urea soluble (US) and urea insoluble (UI) fractions from individual human lenses 1.8 to 65 years of age were isolated from concentric fiber layers. In lenses younger than 19 years, a uniform distribution in the amount of WS, US and UI fractions was found throughout the entire lens. These fracti...

journal_title：Current eye research

authors： Li LK,Roy D,Spector A

更新日期：1986-02-01 00:00:00

abstract：PURPOSE:Retinal pigment epithelial (RPE) cell proliferation is an important step in the pathogenesis of ocular diseases such as proliferative retinopathy. Growth factors play a major role in modulating the development and progression of these diseases. The aim of this study was to examine the effects of single growth f...

journal_title：Current eye research

authors： Kaven CW,Spraul CW,Zavazava NK,Lang GK,Lang GE

更新日期：2000-06-01 00:00:00

abstract：PURPOSE:To quantify the impact of posterior cornea on toric IOL calculation accuracy using Placido-topography of anterior corneal surface and Scheimpflug measurements of corneal thickness. MATERIALS AND METHODS:Three-hundred seventy-nine non-selected eyes undergoing cataract surgery with non-toric intraocular lens (IO...

journal_title：Current eye research

authors： Preussner PR,Hoffmann P,Wahl J

更新日期：2015-01-01 00:00:00

abstract：:In earlier experiments on the role of the cytolytic toxin pneumolysin in ocular infections with pneumococcus, we found that a strain carrying a deletion in the gene encoding pneumolysin was considerably less virulent than wild type when tested in an intracorneal model of keratitis in the rabbit. To confirm this result...

journal_title：Current eye research

authors： Johnson MK,Hobden JA,O'Callaghan RJ,Hill JM

更新日期：1992-12-01 00:00:00

abstract：:VIP markedly stimulates intracellular cAMP accumulation in the human retinoblastoma Y-79 cell line. cAMP increased about 5-fold above the basal level with 10(-8)M VIP and reached a maximum level (about 70-fold increase) with 2 X 10(-6)M VIP. Glucagon at 6 X 10(-8)M significantly increased cAMP accumulation with a maxi...

journal_title：Current eye research

authors： Kyritsis A,Koh SW,Chader GJ

更新日期：1984-02-01 00:00:00

abstract：:Purpose: The purpose of this study is to present the study design and one month's preliminary results of a 2-year randomized trial, Combined Atropine with Orthokeratology (AOK), for myopia control study. Methods: Children aged 6 to <11 years and with 1.00-4.00 D myopia were randomly assigned to AOK group or ortho-k al...

journal_title：Current eye research

authors： Tan Q,Ng AL,Cheng GP,Woo VC,Cho P

更新日期：2019-06-01 00:00:00

abstract：:The compound 2-mercaptoacetyl-L-phenylalanyl-L-leucine (HS-Ac-Phe-Leu) is a potent and specific inhibitor of Pseudomonas aeruginosa elastase, effectively inhibiting the elastase activity both, in vitro and within the rabbit cornea. This inhibitor was therefore evaluated as an adjunct to antibiotics (gentamicin) treatm...

journal_title：Current eye research

authors： Spierer A,Kessler E

更新日期：1984-04-01 00:00:00

abstract：PURPOSE:To compare the clinical outcomes following Descemet's membrane endothelial keratoplasty (DMEK) with 100% air tamponade versus 10% sulfur hexafluoride (SF6) tamponade. METHODS:Retrospective analysis of 108 consecutive DMEK cases subdivided by anterior chamber tamponade with 54 eyes receiving 10% SF6 and 54 eyes...

journal_title：Current eye research

authors： Rickmann A,Szurman P,Jung S,Boden KT,Wahl S,Haus A,Boden K,Januschowski K

更新日期：2018-04-01 00:00:00

abstract：:Bovine vitreous body and aorta contain extractable leukocyte elastase inhibitors, which were purified by gel filtration and affinity chromatography on agarose-pancreatic elastase. The purified inhibitor preparation from aorta was resolved by polyacrylamide gel electrophoresis into a main band migrating slightly faster...

journal_title：Current eye research

authors： Arsenis C,Kuettner KE,Eisenstein R

更新日期：1988-02-01 00:00:00

abstract：:Recent reports from this laboratory indicate that dopamine (DA2) agonists can lower intraocular pressure (IOP) in rabbits, monkeys and rats. This communication suggests that the cat nictitating membrane (CNM) preparation is a useful model for localizing the site(s) and mechanism(s) of action of dopamine (DA2) agonists...

journal_title：Current eye research

authors： Potter DE,Burke JA

更新日期：1984-11-01 00:00:00

abstract：PURPOSE:To characterize the effect of glutamate receptor activation/inhibition on the secretion of vascular endothelial growth factor (VEGF) in retina-specific glial (Müller) cells under experimental conditions of hyperglycemia and hypoxia, two intrinsic pathologic conditions of diabetic retinopathy. METHODS:Purified ...

journal_title：Current eye research

authors： Cervantes-Villagrana AR,Garcia-Román J,González-Espinosa C,Lamas M

更新日期：2010-08-01 00:00:00

abstract：PURPOSE:To examine the efficacy of oral doxycycline treatment (as compared to oral and topical dexamethasone) for inhibiting corneal neovascularization (CNV). METHODS:Following corneal alkali burn, rats were treated daily with oral doxycycline, oral dexamethasone, or topical dexamethasone for 14 days. Control rats wer...

journal_title：Current eye research

authors： Dan L,Shi-long Y,Miao-li L,Yong-ping L,Hong-jie M,Ying Z,Xiang-gui W

更新日期：2008-08-01 00:00:00

abstract：UNLABELLED:Abstract Purpose of the Study: Protein tyrosine phosphatase σ (PTPσ) acts as a neuronal receptor for chondroitin sulfate proteoglycans (CSPGs). CSPGs have inhibitory effects on experience-dependent plasticity and usually form lattice-like cell coatings that surround the parvalbumin (PV) interneurons in the v...

journal_title：Current eye research

authors： Liu H,Xu H,Yu T,Yao J,Zhao C,Yin ZQ

更新日期：2013-10-01 00:00:00

abstract：PURPOSE:The present study was aimed to investigate the expression of purinergic P2 receptors in oxygen-induced retinal neovascularization. METHODS:Immunohistochemistry was used to study the expression of purinergic P2Y2 and P2X2 receptors in the neonatal mouse retina during normal vascular development and after oxygen...

journal_title：Current eye research

authors： Sarman S,Mancini J,van der Ploeg I,Croxatto JO,Kvanta A,Gallo JE

更新日期：2008-03-01 00:00:00

abstract：PURPOSE:Corneal autofluorescence is related to advanced glycation end products formed by glucose that reaches the cornea via the aqueous humour. The aim of the study was to examine the influence on autofluorescence of changes in permeability of the blood aqueous barrier. METHODS:Corneal autofluorescence was measured i...

journal_title：Current eye research

authors： Kessel L,Moldow B,van Best JA,Sander B

更新日期：2003-05-01 00:00:00

abstract：PURPOSE:To investigate the therapeutic role of topical and oral fluconazole treatment using a rabbit model of Aspergillus fumigatus keratitis. METHODS:Aspergillus fumigatus spores were injected into the corneal stroma of the right eye of 20 rabbits. Forty-eight hours later the rabbits were randomly divided into three ...

journal_title：Current eye research

authors： Avunduk AM,Beuerman RW,Warnel ED,Kaufman HE,Greer D

更新日期：2003-02-01 00:00:00

abstract：:We studied the protective effects of passive immunization with virus specific antibody in newborn rabbits inoculated subcutaneously with type 2 herpes simplex virus (HSV-2). Newborn rabbits given anti-HSV-2 antibody intraperitoneally (IP) on days 0, 2 and 4 post infection had smaller herpetic skin lesions and reduced ...

journal_title：Current eye research

authors： Friedlaender RP,Oh JO,Minasi P,Ohashi Y

更新日期：1987-01-01 00:00:00

abstract：:Experiments were conducted to test the influence of thapsigargin on the NaK-ATPase activity of cultured cells (ODM2) derived from human nonpigmented ciliary epithelium. The rate of ouabain-sensitive ATP hydrolysis (Na,K-ATPase activity) was diminished in cells that had been pretreated with thapsigargin then permeabili...

journal_title：Current eye research

authors： Mito T,Kuwahara S,Delamere NA

更新日期：1995-08-01 00:00:00

abstract：AIMS:To investigate whether tobacco smoke directly injures retinal ganglion cells (RGCs) and to evaluate the mechanisms of cell death. METHODS:Primary rat RGCs were harvested from 3- or 4-day-old newborn rats and exposed to cigarette smoke extract (CSE). Cell viability was determined by adenosine 5'-triphosphate (ATP)...

journal_title：Current eye research

authors： Lee K,Hong S,Seong GJ,Kim CY

更新日期：2016-10-01 00:00:00

abstract：:Purpose: To map the time course of changes in intraocular straylight of the human eye 1 year after initial lens wearing for orthokeratology treatment using the objective double-pass technique. Materials and Methods: A total of 35 subjects (19 males and 16 females) completed the study. The mean age was 11.46 ± 2.33 yea...

journal_title：Current eye research

authors： Liu G,Jin N,Bi H,Du B,Gu T,Zhang B,Wei R

更新日期：2019-01-01 00:00:00

abstract：:We adapted a previously described procedure to quantitate collagen in corneal tissue sections prepared from paraffin-embedded samples. The method entailed staining the deparaffinized tissue sections with Sirius red, eluting the bound dye with NaOH-methanol, and estimating the color in a spectrophotometer as an indicat...

journal_title：Current eye research

authors： Yue BY,Sugar J,Schrode K

更新日期：1986-08-01 00:00:00

abstract：PURPOSE:The aim of the present study was to evaluate the efficacy of the inverted internal limiting membrane (ILM) flap technique that involved the use of a perfluorocarbon liquid (PFCL) bubble for the selective prevention of indocyanine green (ICG) staining of the parts of the inverted flap in contact with the retinal...

journal_title：Current eye research

authors： Ra H,Lee WK

更新日期：2019-01-01 00:00:00

abstract：:Objectives: To investigate the characteristics of margin reflex distance 1 (MRD1) asymmetry in congenital lower eyelid epiblepharon and its resolution after surgical correction of epiblepharon. Methods: Among patients who underwent lower eyelid epiblepharon surgery from November 2015 to September 2017, patients with a...

journal_title：Current eye research

authors： Yang MK,Kim N,Choung HK,Khwarg SI

更新日期：2020-12-15 00:00:00

abstract：PURPOSE:To investigate whether zeaxanthin, the predominant carotenoid pigment of the macular pigments in human retina, provides neuroprotection against retinal cell damage. METHODS:We used in vitro cultured retinal ganglion cells (RGCs), specifically RGC-5, an E1A virus-transformed rat cell line. Cell damage was induc...

journal_title：Current eye research

authors： Nakajima Y,Shimazawa M,Otsubo K,Ishibashi T,Hara H

更新日期：2009-04-01 00:00:00

abstract：PURPOSE:To evaluate central corneal thickness (CCT) and corneal volume (CV) in healthy eyes using swept source anterior segment optical coherence tomography (SS-AS-OCT) and other devices. METHODS:Thirty-three healthy right eyes of 33 subjects were investigated. CCT was measured with SS-AS-OCT, rotating Scheimpflug cam...

journal_title：Current eye research

authors： Fukuda R,Usui T,Miyai T,Mori Y,Miyata K,Amano S

更新日期：2013-05-01 00:00:00

abstract：UNLABELLED:Purpose. To develop a rapid and accurate method for the quantification of reduced glutathione (GSH) and oxidized glutathione (GSSG) using micro-quantities of ocular lens. Methods. The epithelium, cortex and nucleus of the lens were separated and also the whole lens was homogenized in 3% metaphosphoric acid. ...

journal_title：Current eye research

authors： Liu S,Ansari NH,Wang C,Wang L,Srivastava SK

更新日期：1996-07-01 00:00:00

abstract：:Purpose/Aim: To determine the associations among socioeconomic factors, delay in management, and high-risk histopathologic features in eyes primarily enucleated for retinoblastoma. Materials and Methods: A single-site survey was conducted from January 2016 through January 2018. Eyes primarily enucleated for unilateral...

journal_title：Current eye research

authors： Xiao W,Ye H,Zeng H,Tang L,Chen R,Gao Y,Mao Y,Yang H

更新日期：2019-10-01 00:00:00

abstract：:Fresh isolates of neonatal human corneal endothelial cells were maintained in tissue culture using a technique employing collagen-coated, dextran-based microcarrier beads. This method provides large yields of endothelial cells suitable for biochemical and/or transplant studies without exposing the cells to enzymatic p...

journal_title：Current eye research

authors： Insler MS,Lopez JG

更新日期：1990-01-01 00:00:00

abstract：PURPOSE/AIM:To quantitatively analyse the evolution of TUNEL-labeling, after in vivo exposure to UVB. METHODS:Altogether, 16 Sprague Dawley rats were unilaterally exposed in vivo for 15 min to close to threshold dose, 5 kJ/m(2), of ultraviolet radiation in the 300 nm wavelength region. Animals were sacrificed in group...

journal_title：Current eye research

authors： Kronschläger M,Yu Z,Talebizadeh N,Meyer LM,Hallböök F,Söderberg PG

更新日期：2013-08-01 00:00:00

abstract：PURPOSE:To investigate the agreement of angular locations of retinal nerve fiber layer (RNFL) defect margins in glaucomatous eyes by using red-free fundus photographs and Cirrus high-definition optical coherence tomography (OCT) RNFL deviation and thickness maps. METHODS:We examined 380 RNFL defects that showed clear ...

journal_title：Current eye research

authors： Hwang YH,Kim YY,Kim HK,Sohn YH

更新日期：2014-11-01 00:00:00