Characterization of active and passive Na+ and K+ transport in normal rat lens by the short-circuiting technique.

abstract：PURPOSE:Disulfiram (DSF) exhibits a wide variety of biological activities, including an anti-inflammatory action, on which we focused our attention. The aim of the present study was to investigate the effect of oral DSF on endotoxin-induced uveitis (EIU) in rats. METHODS:We investigated its effect upon cellular infilt...

journal_title：Current eye research

authors： Kanai K,Itoh N,Yoshioka K,Yonezawa T,Ikadai H,Hori Y,Ito Y,Nagai N,Chikazawa S,Hoshi F,Higuchi S

更新日期：2010-10-01 00:00:00

abstract：PURPOSE:To investigate the agreement of angular locations of retinal nerve fiber layer (RNFL) defect margins in glaucomatous eyes by using red-free fundus photographs and Cirrus high-definition optical coherence tomography (OCT) RNFL deviation and thickness maps. METHODS:We examined 380 RNFL defects that showed clear ...

journal_title：Current eye research

authors： Hwang YH,Kim YY,Kim HK,Sohn YH

更新日期：2014-11-01 00:00:00

abstract：PURPOSE:Phoria is used in the diagnosis of binocular dysfunctions, such as convergence insufficiency. A common treatment for convergence insufficiency is vision therapy, yet it is controversial whether the phoria changes as a result of rehabilitation. Phoria can vary due to the duration and/or the type of prior visual ...

journal_title：Current eye research

authors： Kim EH,Alvarez TL

更新日期：2012-11-01 00:00:00

abstract：:Purpose: To evaluate the effect of isolated oblique muscle weakening on horizontal deviation in patients with A- and V-pattern exotropia.Methods: The medical records of patients who underwent bilateral oblique muscle weakening for A- and V-pattern exotropia associated oblique muscle overaction between 2011 and 2018 we...

journal_title：Current eye research

authors： Wang X,Zhang W,Liu L

更新日期：2020-02-01 00:00:00

abstract：:Purpose: To provide a normative data set of swept-source optical coherence tomography angiography (SS-OCTA) peripapillary vessel density (VD) measurements and assess correlations with age, gender, disc area and axial length (AL). Material and Methods: This was an observational cross-sectional study conducted on 346 ri...

journal_title：Current eye research

authors： Fernández-Vigo JI,Kudsieh B,Shi H,De-Pablo-Gómez-de-Liaño L,Serrano-Garcia I,Ruiz-Moreno JM,Martínez-de-la-Casa JM,García-Feijóo J,Fernández-Vigo JÁ

更新日期：2020-11-01 00:00:00

abstract：:The effects of repeated exposures to UV-A (335 nm) and UV-B (305 nm) radiation on the crystalline lens were studied by treating cultured bovine lenses daily or weekly. The effects of irradiation on lens optical quality were monitored using an automated scanning laser system that records both relative transmittance and...

journal_title：Current eye research

authors： Stuart DD,Cullen AP,Sivak JG,Doughty MJ

更新日期：1994-05-01 00:00:00

abstract：:Purpose/Aim of the study: A recently proposed technique enables the generation of continuously increasing mosaic images of the corneal sub-basal nerve plexus (SNP) using in vivo corneal confocal microscopy (CCM). The aim of the present study was to investigate the progression of the corneal nerve fiber length (CNFL) m...

journal_title：Current eye research

authors： Allgeier S,Winter K,Bretthauer G,Guthoff RF,Peschel S,Reichert KM,Stachs O,Köhler B

更新日期：2017-04-01 00:00:00

abstract：:Four days after corneal inoculation of mice with herpes simplex (type 1) virus (HSV), infected trigeminal ganglion cells with and without calcitonin gene-related peptide (CGRP) antigenicity were examined by electron microscopy in sections treated with colloidal gold labeled antibodies. Cells that contain CGRP were ide...

journal_title：Current eye research

authors： LaVail JH,Meade LB,Dawson CR

更新日期：1991-01-01 00:00:00

abstract：PURPOSE:Ethacrynic acid (ECA) has been shown to increase facility of aqueous outflow in whole eyes and perfused anterior segments, to open up spaces between cells in the trabecular meshwork and inner wall of Schlemm's canal, and to cause separation and retraction of trabecular meshwork and endothelial cells in culture....

journal_title：Current eye research

authors： O'Brien ET,Lee RE 3rd,Epstein DL

更新日期：1996-09-01 00:00:00

abstract：PURPOSE:The present study was conducted to develop and characterize a functional primary culture of pigmented rabbit conjunctival epithelial cells on permeable support exhibiting tight barrier properties. METHODS:Conjunctival epithelial cells were isolated by 0.2% protease treatment, cultured at 0.5-1.8 x 10(6) cells/...

journal_title：Current eye research

authors： Saha P,Kim KJ,Lee VH

更新日期：1996-12-01 00:00:00

abstract：PURPOSE:The mechanism by which prostaglandin(PG)F2 alpha increases uveoscleral outflow and lowers intraocular pressure in primates is not known. In cultured human ciliary muscle cells, PGF2 alpha induces the expression of the protooncogene c-fos which is known to induce the transcription of genes such as matrix metallo...

journal_title：Current eye research

authors： Lindsey JD,Kashiwagi K,Boyle D,Kashiwagi F,Firestein GS,Weinreb RN

更新日期：1996-08-01 00:00:00

abstract：:The mechanism of oxidative damage to the lens through intraocular photochemical generation of superoxide and its derivatization to other oxidants such as singlet oxygen, hydroxyl radical and hydrogen peroxide has been studied. Rat lenses when organ cultured aerobically in TC 199 containing additional amounts of ribofl...

journal_title：Current eye research

authors： Varma SD,Chand D,Sharma YR,Kuck JF Jr,Richards RD

更新日期：1984-01-01 00:00:00

abstract：AIM:To compare patient satisfaction and experience after external dacryocystorhinostomy (EX-DCR) versus transcanalicular DCR (TC-DCR) with a diode laser and to evaluate the change in quality of life following simultaneous bilateral DCR. METHODS:Prospective evaluation of 38 eyes of 19 patients with bilateral nasolacrim...

journal_title：Current eye research

authors： Yeniad B,Uludag G,Kozer-Bilgin L

更新日期：2012-04-01 00:00:00

abstract：:Forty-five patients with virologically confirmed dendritic keratitis were treated in a randomized, double-blind controlled study with a basic therapy of trifluorothymidine (TFT) eye drops. In addition they received different human recombinant interferon (rHu IFN) eye drops. The following results were obtained for aver...

journal_title：Current eye research

authors： Sundmacher R,Mattes A,Neumann-Haefelin D,Adolf G,Kruss B

更新日期：1987-01-01 00:00:00

abstract：:Achieving the long-term goal of successful engraftment of retinal tissues into eyes blinded by endogenous retinal failure will depend, at least in part, on controlling the immune response to antigens expressed on retinal grafts. Since histoincompatible tissues will have to be used for such transplants, methods to cont...

journal_title：Current eye research

authors： Jiang LQ,Streilein JW

更新日期：1992-07-01 00:00:00

abstract：:Reduced glutathione (0.3 mM) stimulates the activity of sodium-potassium activated ATPase (Na+K+ATPase) by 54% in plasma membranes prepared from bovine corneal endothelial cells. Oxidized glutathione, however, has no effect on Na+K+ATPase activity in the same tissue, although it does inhibit magnesium activated ATPase...

journal_title：Current eye research

authors： Whikehart DR,Soppet DR

更新日期：1981-01-01 00:00:00

abstract：PURPOSE:To characterize the possible cytotoxic effects of oxysterols (7beta-hydroxycholesterol (7beta-OH), 25-hydroxycholesterol (25-OH)) in human retinal pigment epithelial cells (ARPE-19) and to detail the relationships between some of these effects. METHODS:ARPE-19 cells were treated with 7beta-OH and 25-OH. Cell v...

journal_title：Current eye research

authors： Malvitte L,Montange T,Vejux A,Joffre C,Bron A,Creuzot-Garcher C,Lizard G

更新日期：2008-09-01 00:00:00

abstract：PURPOSE:To study retinal neovascularization (RNV) inhibition by intravitreal injections (IVs) of ranibizumab, sTie2 fusion protein (sTie2-Fc), and a combined therapy in an oxygen-induced retinopathy (OIR) model. MATERIALS AND METHODS:An OIR mouse model was used to simulate RNV in retinopathy of prematurity (ROP); and ...

journal_title：Current eye research

authors： Jiang C,Ruan L,Zhang J,Huang X

更新日期：2018-09-01 00:00:00

abstract：:In these experiments we characterize rabbit and bovine corneal endothelia cell cultured on microporous membrane filters (0.6cm2). Cell cultured bovine or rabbit corneal endothelial cells (subcultures 1-3) were seeded onto Millicell-HA filter inserts. Electrical resistance measured across the cultured monolayers increa...

journal_title：Current eye research

authors： Geroski DH,Hadley A

更新日期：1992-01-01 00:00:00

abstract：PURPOSE:To assess the distribution of dark-light changes in iris features and associated factors amongst American Caucasians, American Chinese and mainland Chinese aged 40 years and over. METHODS:Four gender- and age-matched cohorts: Caucasians, American Chinese, Southern Chinese and Northern Chinese comprised the stu...

journal_title：Current eye research

authors： Wang D,He M,Wu L,Kao A,Pekmezci M,Singh K,Lin S

更新日期：2012-07-01 00:00:00

abstract：:To investigate the role of lymphocytes in the pathogenesis of uveitis, we analyzed the expression of memory markers, CD29 and CD45RO antigens, and apoptosis-related Fas antigen on T lymphocytes in the aqueous humor (AH) and peripheral blood (PB) from patients with uveitis. Using three-color flow cytometry, we assessed...

journal_title：Current eye research

authors： Ohta K,Norose K,Wang XC,Ito S,Yano A,Segawa K

更新日期：1996-03-01 00:00:00

abstract：PURPOSE:Several procedures in cataract surgery carry the risk of high temperature increases in the capsular bag. The present study was undertaken to determine the shrinkage temperature of the human lens capsule and to investigate the effect of temperature on the mechanical behavior of the lens capsule. METHOD:Thermal-...

journal_title：Current eye research

authors： Krag S,Danielsen CC,Andreassen TT

更新日期：1998-05-01 00:00:00

abstract：:Inoculation of herpes simplex virus Type 1 into the anterior chamber of BALB/c mice induces a characteristic ocular infection involving primarily the anterior segment of virus-injected eyes and the retina of contralateral uninjected eyes. In the BALB/c strain, which is susceptible to herpetic retinitis, anti-HSV delay...

journal_title：Current eye research

authors： Whittum-Hudson JA,Pepose JS

更新日期：1988-02-01 00:00:00

abstract：PURPOSE:Maintaining mature and viable retinal pigment epithelial cells (RPE) in vitro has proven challenging. Investigating compounds that can promote RPE-viability and maturation is motivated by RPE transplantation research, the quest to understand RPE physiology, and a desire to modulate RPE in pathological states. W...

journal_title：Current eye research

authors： Khan AZ,Utheim TP,Moe MC,Aass HCD,Sapkota D,Vallenari EM,Eidet JR

更新日期：2020-09-01 00:00:00

abstract：:We assessed in vitro the antimicrobial activity of four agents (vancomycin, teicoplanin, mupirocin, and imipenem) which are effective against Gram-positive cocci causally associated with bacterial keratitis, as well as their corneal epithelial cytotoxicity. Minimal inhibitory concentrations inhibiting 90% of strains (...

journal_title：Current eye research

authors： Cutarelli PE,Lazarus HM,Jacobs MR,Lass JH

更新日期：1993-07-01 00:00:00

abstract：:The efficiency of protein immobilization to provide a hydrogel surface with a high affinity for corneal epithelial cells was investigated. The cell adhesive proteins collagen and fibronectin, and the cell adhesive oligopeptide RGDS (arginine-glycine-aspartic acid-serine) were successfully covalently immobilized on pol...

journal_title：Current eye research

authors： Kobayashi H,Ikada Y

更新日期：1991-10-01 00:00:00

abstract：PURPOSE:Psychiatric conditions and not just the treatments themselves might be involved in the pathophysiology of dry eye disease (DED). The aim of our study was to evaluate the association between depression and DED using objective and subjective tests in patients with newly diagnosed depressive disorder who were not ...

journal_title：Current eye research

authors： Tiskaoglu NS,Yazıcı A,Karlıdere T,Sari E,Oguz EY,Musaoglu M,Aslan S,Samet Ermiş S

更新日期：2017-05-01 00:00:00

abstract：:A reduced nicotinamide adenine dinucleotide phosphate (NAD(P)H)-dependent hydrogen peroxide-generating activity of rat ocular tissue was investigated cytochemically utilizing the cerium method. NADPH or NADH oxidation resulted in electron-dense fine granular deposits on the corneal epithelial and endothelial plasma me...

journal_title：Current eye research

authors： Atalla LR,Sevanian A,Rao NA

更新日期：1988-09-01 00:00:00

abstract：PURPOSE:To compare the differences in higher-order aberrations (HOAs) after laser subepithelial keratomileusis (LASEK) between two different laser platforms. METHODS:One hundred and seven eyes of 107 patients were included in this study. Fifty-six eyes underwent LASEK with the Triple-A profile (an ablation profile of ...

journal_title：Current eye research

authors： Liu L,Li M,Shi YH,Sun LN,Wang F,Zou J

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:To develop a standardized method for measuring from iris photographs, light and dark segments of areas and densities of iris color. METHODS:Computerized image analysis was used to measure the iris photographs. The reproducibility of this method was studied in 30 normal eyes with three different colored irides,...

journal_title：Current eye research

authors： Takamoto T,Schwartz B,Cantor LB,Hoop JS,Steffens T

更新日期：2001-06-01 00:00:00