Steroid inhibition of limbal blood and lymphatic vascular cell growth.

abstract：PURPOSE:To investigate the morphological or functional differences of retina in amblyopia. MATERIALS AND METHODS:Forty-one patients with unilateral strabismic, anisometropic or combined amblyopia were included in the study. A control group was composed of 16 normal children. All participants were tested with optical c...

journal_title：Current eye research

authors： Tugcu B,Araz-Ersan B,Kilic M,Erdogan ET,Yigit U,Karamursel S

更新日期：2013-07-01 00:00:00

abstract：:In earlier experiments on the role of the cytolytic toxin pneumolysin in ocular infections with pneumococcus, we found that a strain carrying a deletion in the gene encoding pneumolysin was considerably less virulent than wild type when tested in an intracorneal model of keratitis in the rabbit. To confirm this result...

journal_title：Current eye research

authors： Johnson MK,Hobden JA,O'Callaghan RJ,Hill JM

更新日期：1992-12-01 00:00:00

abstract：:The effect of cyclosporine (CsA) treatment in both primary and secondary Chlamydia trachomatis ocular infection in cynomolgus monkeys was studied. Following primary infection, CsA-treated animals developed severe clinical symptoms which persisted for up to 12 weeks compared to control animals which developed less seve...

journal_title：Current eye research

authors： Young E,Schachter J,Prendergast RA,Taylor HR

更新日期：1987-05-01 00:00:00

abstract：PURPOSE:The purposes of this study were to investigate the effects of topically administrated Tacrolimus and Octreotide on modulation of postoperative scarring in experimental glaucoma filtration surgery and to compare the antifibrotic properties of these agents with mitomycin-C (MMC). MATERIAL AND METHODS:A total of ...

journal_title：Current eye research

authors： Arslan S,Aydemir O,Güler M,Dağlı AF

更新日期：2012-03-01 00:00:00

abstract：PURPOSE:To examine the efficacy of oral doxycycline treatment (as compared to oral and topical dexamethasone) for inhibiting corneal neovascularization (CNV). METHODS:Following corneal alkali burn, rats were treated daily with oral doxycycline, oral dexamethasone, or topical dexamethasone for 14 days. Control rats wer...

journal_title：Current eye research

authors： Dan L,Shi-long Y,Miao-li L,Yong-ping L,Hong-jie M,Ying Z,Xiang-gui W

更新日期：2008-08-01 00:00:00

abstract：:In primates, ciliary muscle contraction causes accommodation and facilitates aqueous outflow. In living rhesus monkeys, accommodative, outflow facility, and ciliary muscle movement responses to cholinergic agonists all decline with age. We developed an apparatus to determine in vitro whether the latter is related to i...

journal_title：Current eye research

authors： Poyer JF,Kaufman PL,Flügel C

更新日期：1993-05-01 00:00:00

abstract：PURPOSE:To evaluate central corneal thickness (CCT) and corneal volume (CV) in healthy eyes using swept source anterior segment optical coherence tomography (SS-AS-OCT) and other devices. METHODS:Thirty-three healthy right eyes of 33 subjects were investigated. CCT was measured with SS-AS-OCT, rotating Scheimpflug cam...

journal_title：Current eye research

authors： Fukuda R,Usui T,Miyai T,Mori Y,Miyata K,Amano S

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:Corneal scarring is a common poor outcome of corneal trauma. Transforming growth factor β-1 plays a vital role in corneal fibrosis, inducing keratocyte transformation to myofibroblasts. Other than corneal transplantation, no other curative treatment methods for corneal scarring are currently available. Hypercap...

journal_title：Current eye research

authors： Chang YM,Cian AA,Weng TH,Liang CM,Pao SI,Chen YJ

更新日期：2020-09-11 00:00:00

abstract：:With Golgi impregnation, a simple amacrine cell type is described in the chick retina. The most relevant morphological feature of these retinal neurons is a single straight, radial trunk which dichotomizes tangentially in a rectilinear expansion in the 5th stratum of the inner plexiform layer (IPL). ...

journal_title：Current eye research

authors： Genis-Galvez JM,Chmielewski CE,Prada FA

更新日期：1989-02-01 00:00:00

abstract：PURPOSE:Klotho genes are expressed in limited tissues and have been found to be a pathogenic factor of age-related diseases in mammals, but their expressions and functions in human eyes are yet to be defined. This study was performed to investigate the expression of Klotho family genes in human ocular tissues and anter...

journal_title：Current eye research

authors： Zhang Y,Wang L,Wu Z,Yu X,Du X,Li X

更新日期：2017-06-01 00:00:00

abstract：PURPOSE:Acyclovir has been shown to be effective in preventing recurrent herpes simplex virus lesions of the genitalia and oral labia. The purpose of the current study was to determine the effect of acyclovir on the appearance of infectious virus in the peripheral nervous system and in an end organ, the eye. MATERIALS...

journal_title：Current eye research

authors： Gebhardt BM,Kaufman HE,Hill JM

更新日期：2004-08-01 00:00:00

abstract：:The ocular penetration pathways of three alpha 2-adrenergic agents (p-aminoclonidine, AGN 190342, and clonidine) were investigated in rabbits both in vitro and in vivo. The corneal permeabilities of the compounds correlated positively with their octanol/water distribution coefficients. The ocular drug absorption via c...

journal_title：Current eye research

authors： Chien DS,Homsy JJ,Gluchowski C,Tang-Liu DD

更新日期：1990-11-01 00:00:00

abstract：PURPOSE:Intrastromal epithelial migration occurs following deep excimer annular keratectomy. Our purpose is to determine the localization of gelatinase B expression and its relationship to migrating intrastromal epithelial cells following deep annular excimer keratectomy. METHODS:Rabbit corneas were treated with deep ...

journal_title：Current eye research

authors： Maeda M,Vanlandingham BD,Ye H,Lu PC,Azar DT

更新日期：1998-08-01 00:00:00

abstract：PURPOSE:To assess the distribution of dark-light changes in iris features and associated factors amongst American Caucasians, American Chinese and mainland Chinese aged 40 years and over. METHODS:Four gender- and age-matched cohorts: Caucasians, American Chinese, Southern Chinese and Northern Chinese comprised the stu...

journal_title：Current eye research

authors： Wang D,He M,Wu L,Kao A,Pekmezci M,Singh K,Lin S

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:The purpose was to investigate the effect of the superoxide dismutase mimetic tempol on decreases in retinal blood flow that are found in diabetic mice. MATERIALS AND METHODS:Streptozotocin (STZ) was injected into male C57BL/6 mice to induce hyperglycemia. One week following the STZ injection, subsets of the m...

journal_title：Current eye research

authors： Yadav AS,Harris NR

更新日期：2011-05-01 00:00:00

abstract：PURPOSE:To examine the effect of elevated extracellular glucose, thus simulating diabetes, on migration, adhesion and proliferation of SV40 transformed human corneal epithelial (HCE) cells. METHODS:HCE cells were maintained in serum supplemented media containing 5 mM, 17.5 mM or 38 mM D-glucose. Cell migration was det...

journal_title：Current eye research

authors： McDermott AM,Kern TS,Murphy CJ

更新日期：1998-09-01 00:00:00

abstract：PURPOSE:Nona-D-arginine amide (D9R) affected a cure of Pseudomonas aeruginosa corneal disease when combined with ciprofloxacin. In this study, we show that D9R alone and prophylactic treatment with D9R significantly reduced corneal pathology and bacterial burden associated with P. aeruginosa infection. MATERIALS AND M...

journal_title：Current eye research

authors： Karicherla P,Hobden JA

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:Acanthamoeba keratitis is a sight-threatening corneal infection. It is known that: (i) more amoebae bind to the surface of injured corneas than to the normal corneal surface and (ii) mannose-containing glycoproteins (GPs) possess binding sites for Acanthamoeba. The present study was undertaken to determine whet...

journal_title：Current eye research

authors： Jaison PL,Cao Z,Panjwani N

更新日期：1998-08-01 00:00:00

abstract：:The effect of electrical stimulation of the sympathetic nerves on the blood-aqueous barrier was investigated in rabbits. The permeability of the barrier was assessed during either acute, chronic or following chronic nerve stimulation. During acute and chronic stimulation of the sympathetic nerves, fluorescein entered ...

journal_title：Current eye research

authors： Bartels SP,Pawlowski AM

更新日期：1990-10-01 00:00:00

abstract：UNLABELLED:Abstract Purpose of the Study: Protein tyrosine phosphatase σ (PTPσ) acts as a neuronal receptor for chondroitin sulfate proteoglycans (CSPGs). CSPGs have inhibitory effects on experience-dependent plasticity and usually form lattice-like cell coatings that surround the parvalbumin (PV) interneurons in the v...

journal_title：Current eye research

authors： Liu H,Xu H,Yu T,Yao J,Zhao C,Yin ZQ

更新日期：2013-10-01 00:00:00

abstract：PURPOSE:The aim of this study was to characterize a standardized porcine ex-vivo testing system for intraocular pressure (IOP) monitoring after vitrectomy with different endotamponades. METHODS:Twenty-four pig eyes, six per endotamponade group were obtained immediately postmortem. After pars plana vitrectomy, vitreous...

journal_title：Current eye research

authors： Ebner M,Mariacher S,Hurst J,Szurman P,Schnichels S,Spitzer MS,Januschowski K

更新日期：2017-08-01 00:00:00

abstract：:Thyroxine-treated human lens epithelial cells, HLE B-3, were grown in either a normoxic or hyperoxic atmosphere as a first step in identifying factors related to their increased viability. Reactive oxygen species, ROS, and the apparent mitochondrial membrane potential, Delta Psi(m), were measured using fluorescent pro...

journal_title：Current eye research

authors： Huang L,Yappert MC,Jumblatt MM,Borchman D

更新日期：2008-07-01 00:00:00

abstract：PURPOSE:To compare objective optical quality, ocular scattering and aberrations of eyes implanted with an aspheric monofocal intraocular lens (IOL) or an aspheric apodized diffractive multifocal IOL three months after surgery. METHODS:Prospective consecutive nonrandomized comparative cohort study. A total of 80 eyes f...

journal_title：Current eye research

authors： Liao X,Lin J,Tian J,Wen B,Tan Q,Lan C

更新日期：2018-06-01 00:00:00

abstract：:The intraocular inflammatory reaction in a murine model of herpes simplex keratouveitis was studied using immunohistochemical techniques. 5 x 10(5) PFU of HSV-1 (Stewart strain) was applied to the abraded cornea of BALB/c mice. The subsequent development of keratouveitis was documented by sequential examination, conve...

journal_title：Current eye research

authors： Wang HM,Sheu MM,Stulting RD,Kaplan HJ

更新日期：1989-01-01 00:00:00

abstract：:We studied the effects of a forskolin suspension on intraocular pressure (IOP) in normal albino and pigmented rabbits and in alpha-chymotrypsin induced ocular hypertensive rabbits. Experimental-induced ocular hypertensive rabbits were produced by injecting of alpha-chymotrypsin (167 units) into the posterior chamber o...

journal_title：Current eye research

authors： Shibata T,Mishima H,Kurokawa T

更新日期：1988-07-01 00:00:00

abstract：PURPOSE:In the mature retina retinoic acid (RA) biosynthesis was reported to be regulated by light. RA is of vital importance for proper function of the retina. RA activity is mediated by interaction with nuclear retinoic acid receptors (RARs) and retinoid X receptors (RXRs). The purpose of this study was to determine ...

journal_title：Current eye research

authors： Janssen JJ,Kuhlmann ED,van Vugt AH,Winkens HJ,Janssen BP,Deutman AF,Driessen CA

更新日期：1999-10-01 00:00:00

abstract：:The effects of repeated exposures to UV-A (335 nm) and UV-B (305 nm) radiation on the crystalline lens were studied by treating cultured bovine lenses daily or weekly. The effects of irradiation on lens optical quality were monitored using an automated scanning laser system that records both relative transmittance and...

journal_title：Current eye research

authors： Stuart DD,Cullen AP,Sivak JG,Doughty MJ

更新日期：1994-05-01 00:00:00

abstract：AIM:To compare patient satisfaction and experience after external dacryocystorhinostomy (EX-DCR) versus transcanalicular DCR (TC-DCR) with a diode laser and to evaluate the change in quality of life following simultaneous bilateral DCR. METHODS:Prospective evaluation of 38 eyes of 19 patients with bilateral nasolacrim...

journal_title：Current eye research

authors： Yeniad B,Uludag G,Kozer-Bilgin L

更新日期：2012-04-01 00:00:00

abstract：:The compound 2-mercaptoacetyl-L-phenylalanyl-L-leucine (HS-Ac-Phe-Leu) is a potent and specific inhibitor of Pseudomonas aeruginosa elastase, effectively inhibiting the elastase activity both, in vitro and within the rabbit cornea. This inhibitor was therefore evaluated as an adjunct to antibiotics (gentamicin) treatm...

journal_title：Current eye research

authors： Spierer A,Kessler E

更新日期：1984-04-01 00:00:00

abstract：:Purpose: The purpose of this study was to investigate the relationship between aquaporin-1 (AQP-1) protein expression in the choroid and choroid thickness (CT) during the recovery of form-deprivation (FD) myopia in guinea pigs.Materials and Methods: Seventy-two guinea pigs were randomly assigned to the normal control ...

journal_title：Current eye research

authors： Chen W,Zhang H,Zhang Y,Wang Q,Wang Y,Li ZW

更新日期：2020-06-01 00:00:00