Abstract：
OBJECTIVE:The aim of this review is to evaluate the efficacy of available Purtscher's Retinopathy treatments. MATERIALS AND METHODS:In order to collect single-case reports, electronic searches were conducted in several databases including PubMed, Embase, Web of Science, China National Knowledge Infrastructure, SinoMed, VIP, and WanFang in the Electronic Theses and Dissertations Center. In VIP and Wanfang, we also traced the references of included articles. Risk of bias was evaluated using a tool adapted from the Cochrane Risk of Bias Tool. Statistical analysis was done in SPSS19.0. Evidence was evaluated and graded with GRADE system. RESULTS:In total, 76 studies were included involving 88 cases and 139 eyes. Serious bias existed in 90% of the included studies. Current treatments for Purtscher's retinopathy included glucocorticoid therapy (63.29%), traditional Chinese medicine therapy (10.13%), glucocorticoid integrative medicine therapy (7.60%), and integrative medicine therapy (6.33%). Patients' eyesight with (56.83%) or without (43.17%) treatment both improved in the follow-up within 1-3 months, 4-6 months, and more than 6 months; however, conditions without treatment became better compared to the treatment groups in after 4-6 months and more than 6 months. All results were "very low" in the GRADE system. None of the studies reported adverse reactions in any patient. CONCLUSIONS:Both treatment and no treatment improve vision in Purtscher's retinopathy patients, but the difference between no treatment and glucocorticoid therapy had no statistical significance. The evidence quality for this conclusion was "very low" and had large bias. Further research is required to understand the safety of Purtscher's retinopathy treatment.
journal_name
Curr Eye Resjournal_title
Current eye researchauthors
Xia D,Chen X,Zhou Q,Xiao S,Yu Y,Wang Y,Du G,Huang H,Zhang W,Chen Ydoi
10.1080/02713683.2016.1255335subject
Has Abstractpub_date
2017-06-01 00:00:00pages
908-917issue
6eissn
0271-3683issn
1460-2202journal_volume
42pub_type
杂志文章,评审abstract：PURPOSE:To determine the cellular mechanisms involved in the hypoxia-induced alteration of the retinal pigment epithelium (RPE) potentials and the light-evoked responses of the RPE in chicks. In addition, to determine the mechanisms involved in the recovery of the RPE during the post-hypoxic period. METHODS:In vitro p...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.1080/02713689808951219
更新日期：1998-04-01 00:00:00
abstract：PURPOSE:To investigate whether zeaxanthin, the predominant carotenoid pigment of the macular pigments in human retina, provides neuroprotection against retinal cell damage. METHODS:We used in vitro cultured retinal ganglion cells (RGCs), specifically RGC-5, an E1A virus-transformed rat cell line. Cell damage was induc...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.1080/02713680902745408
更新日期：2009-04-01 00:00:00
abstract：PURPOSE:To learn if peripheral nerve pathways are necessary for corneal expansion and anterior segment growth under a 12-hr light:dark cycle or for the inhibition of corneal expansion under constant light rearing. METHODS:Recently hatched White Leghorn chicks under anesthesia received unilateral ciliary ganglionectomy...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.1080/02713680600738127
更新日期：2006-06-01 00:00:00
abstract：PURPOSE:Chloride efflux plays an important role in aqueous humor production. Chloride currents have been described in bovine non-pigmented ciliary epithelium (NPE), in transformed cultured human NPE, and in bovine volume-activated chloride channels described in the latter. It is the basolateral membranes of the NPE of ...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.1076/ceyr.16.7.710.5064
更新日期：1997-07-01 00:00:00
abstract：PURPOSE:Histidine is an indispensable amino acid with an imidazole ring and it is a precursor of histamine, carnosine, and anserine. Histidine has been proposed to act as a neurotransmitter or neuromodulator in mammalian central nervous system (CNS), including retina. In this study, we report histidine-like immunoreact...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.1076/ceyr.16.6.600.5084
更新日期：1997-06-01 00:00:00
abstract：:Intraocular synthesis of IgG antibodies against HSV (herpes simplex virus), CMV (cytomegalovirus) and VZV (varicella zoster virus) is considered as an indirect proof of uveoretinal infection. Paired serum and aqueous samples obtained from 16 patients with retinitis associated with AIDS, 3 patients with ARN, 8 patients...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.3109/02713689008999412
更新日期：1990-01-01 00:00:00
abstract：PURPOSE:In tissues outside the brain, vascular endothelial growth factor-A (VEGF) causes vascular hyper-permeability by opening of inter-endothelial junctions and induction of fenestrations and vesiculo-vacuolar organelles (VVOs). In preliminary studies, we observed that in blood-retinal barrier endothelium, other cell...
journal_title：Current eye research
pub_type： 杂志文章
doi：
更新日期：2000-08-01 00:00:00
abstract：:Importance: To analyze the characteristics and risk factors for pupillary capture (PC) of the intraocular lens (IOL) in congenital ectopia lentis (CEL) patients.Methods: Data of CEL patients who underwent lens extraction and intraocular implantation from 2013 to 2016 at Zhongshan Ophthalmic Center in China were collec...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.1080/02713683.2019.1668418
更新日期：2020-04-01 00:00:00
abstract：PURPOSE:This study was performed to compare the positive predictive value of peripapillary retinal nerve fiber layer (RNFL) thickness measurements obtained using Cirrus high-definition optical coherence tomography (Cirrus HD-OCT; Carl Zeiss Meditec, Dublin, CA) and spectral OCT/scanning laser ophthalmoscopy (SLO) (OPKO...
journal_title：Current eye research
pub_type： 临床试验,杂志文章
doi：10.3109/02713683.2013.824989
更新日期：2014-01-01 00:00:00
abstract：:EDGF, a growth factor purified from bovine retina is able to increase the rate of wound healing of rabbit corneal epithelium in a dose dependent way. Two applications a day are enough to obtain the maximum rate. The most purified preparation of EDGF is as effective as EGF or pFGF in promoting this phenomenon and allow...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.3109/02713688409003059
更新日期：1984-04-01 00:00:00
abstract：PURPOSE:The aim of this study was to characterize a standardized porcine ex-vivo testing system for intraocular pressure (IOP) monitoring after vitrectomy with different endotamponades. METHODS:Twenty-four pig eyes, six per endotamponade group were obtained immediately postmortem. After pars plana vitrectomy, vitreous...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.1080/02713683.2017.1297461
更新日期：2017-08-01 00:00:00
abstract：PURPOSE:To evaluate the stability of successive applanation tonometry measurements in glaucomatous eyes. METHODS:A prospective, comparative, randomized, and evaluator-masked study was conducted in a tertiary medical center. Sixty-seven patients with glaucoma attending our glaucoma clinic underwent four successive intr...
journal_title：Current eye research
pub_type： 杂志文章,随机对照试验
doi：10.3109/02713681003678824
更新日期：2010-06-01 00:00:00
abstract：PURPOSE:To determine the plasma levels of the sulfur-containing amino-acids homocysteine, cysteine, cysteinylglycine, glutamylcysteine, glutathione, and taurine in patients with central retinal vein occlusion (CRVO) and in healthy subjects and to ascertain whether there are statistically significant differences between...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.3109/02713681003698863
更新日期：2010-07-01 00:00:00
abstract：PURPOSE:To compare serum levels of chemerin in type 2 diabetes mellitus (T2DM) with or without retinopathy, and to investigate the relationship between serum chemerin levels and diabetes retinopathy. MATERIALS AND METHODS:A total of 60 T2DM patients and 20 healthy subjects (control group) were enrolled in this study. ...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.3109/02713683.2015.1004718
更新日期：2016-01-01 00:00:00
abstract：PURPOSE:To determine retinal vessel diameter variations in response to neuronal activity induced by diffuse luminance flicker. METHODS:The diameter of retinal arteries and veins was measured in 9 normal subjects by computer analysis of fundus pictures taken in monochromatic light under normal conditions of illuminatio...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.1076/ceyr.16.12.1252.5021
更新日期：1997-12-01 00:00:00
abstract：:We measured the relative solubility of collagen in acetic acid after pepsin digestion and tentatively identified the types of collagen present in corneas of rabbits of various ages and in corneal scar tissue, using hydroxyproline assays and polyacrylamide gel electrophoretic analyses. More than 80% of the collagen in ...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.3109/02713688109019966
更新日期：1981-01-01 00:00:00
abstract：PURPOSE:Whereas many previous studies have identified the association between sustained near work and myopia, few have assessed the influence of concomitant levels of cognitive effort. This study investigates the effect of cognitive effort on near-work induced transient myopia (NITM). METHODS:Subjects comprised of six...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.1076/ceyr.27.6.363.18190
更新日期：2003-12-01 00:00:00
abstract：PURPOSE:To develop an improved diagnostic test for rod-cone dysplasia type 1 (rcd1). The rcd1 phenotype is an early onset, autosomal recessive disease caused by a mutation in the canine rod cyclic GMP phosphodiesterase beta-subunit (PDE6B) gene. A G to A transition in codon 807 at nucleotide position 2420 results in a ...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.3109/02713689609000770
更新日期：1996-05-01 00:00:00
abstract：:Purpose: To determine the refractive astigmatism following toric intraocular lens (tIOL) implantation without consideration of posterior keratometric astigmatism with a conventional tIOL calculator for eyes with low keratometric astigmatism (0.75D to 2.5D) and to theoretically compare the outcomes with predicted refra...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.1080/02713683.2019.1638418
更新日期：2019-12-01 00:00:00
abstract：PURPOSE:To investigate the potential toxicity of the vehicle used for triamcinolone acetonide (TA) to the cornea, lens, ciliary body, and retina of pigmented rabbits. METHODS:Forty chinchilla rabbits (40 eyes) were divided into four groups: group A (control group) eyes received an intravitreal injection of 0.1 ml ster...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.1080/02713680903063082
更新日期：2009-09-01 00:00:00
abstract：PURPOSE:To investigate the effects of citicoline on upregulated clusterin and retinal damage induced by kainic acid (KA). METHODS:KA was injected into the vitreous of rats. Effects of systemic citicoline treatments were estimated by measuring the thickness of the various retinal layers, immunoblotting, and immunohisto...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.1080/02713680701758719
更新日期：2007-12-01 00:00:00
abstract：PURPOSE:This study was carried out in order to determine the most potent and novel uveitopathogenic sites of recoverin using synthetic peptides. METHODS:Several synthetic peptides containing the recoverin sequence plus adjuvants were injected into Lewis rats, and the uveitopathogenic sequence was defined, clinically, ...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.1076/ceyr.22.4.304.5503
更新日期：2001-04-01 00:00:00
abstract：PURPOSE:To evaluate the effect of the birth weight and the postconceptional age on the tear production of preterm and term newborn infants and to evaluate the changes in tear production during the first two months of life. SUBJECTS--METHODS: Both eyes of medically stable term and preterm infants were included in the st...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.1076/ceyr.28.2.145.26235
更新日期：2004-02-01 00:00:00
abstract：PURPOSE:Both HSV-1 and HSV-2 express LAT during viral latency. Previous studies indicated that deletion of either LAT impairs viral reactivation from latency, but that the HSV-1 LAT confers the ability to reactivate efficiently from trigeminal ganglia onto HSV-2. We sought to determine whether the HSV-2 LAT could funct...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.1076/ceyr.26.3.219.14896
更新日期：2003-03-01 00:00:00
abstract：PURPOSE:Most studies of cell growth of the RPE employ cultures which have been previously passaged, but here we investigated freshly-explanted RPE cells, which may have been growth-quiescent for years, within the eye to determine whether co-culture affects initial outgrowth in primary culture. METHODS:Bovine or human ...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.1076/ceyr.16.9.891.5051
更新日期：1997-09-01 00:00:00
abstract：:A method is described for the preparation of plasma membrane enriched fractions from bovine retinal pigment epithelium (RPE) by means of differential centrifugation followed by the use of self forming gradients of Percoll. A detailed analysis of the distribution of organelle specific markers (nuclei, mitochondria, lys...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.3109/02713688409000806
更新日期：1984-09-01 00:00:00
abstract：PURPOSE:To compare the clinical outcomes following Descemet's membrane endothelial keratoplasty (DMEK) with 100% air tamponade versus 10% sulfur hexafluoride (SF6) tamponade. METHODS:Retrospective analysis of 108 consecutive DMEK cases subdivided by anterior chamber tamponade with 54 eyes receiving 10% SF6 and 54 eyes...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.1080/02713683.2018.1431286
更新日期：2018-04-01 00:00:00
abstract：PURPOSE:We recently demonstrated that direct subretinal (SR) injection of adeno-associated virus (AAV) type 8 (AAV8) into photoreceptor cells and retinal pigment epithelium (RPE) is a highly efficient model of gene delivery. The current study compared transduction efficiency and expression patterns associated with vari...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.3109/02713683.2013.779720
更新日期：2013-05-01 00:00:00
abstract：PURPOSE:The aim of this study was to report on the evaluation of corneal nerve fiber density and corneal sensation after accelerated corneal collagen cross-linking on keratoconus patients. METHODS:The study was performed on 30 keratoconus eyes (30 participants: 16 M, 14 F; 17-32 years old) treated with accelerated col...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.3109/02713683.2014.932387
更新日期：2015-05-01 00:00:00
abstract：:Cytoskeletal and membrane proteins were isolated from respectively the urea-soluble and urea-insoluble fractions of the squid lens. The main cytoskeletal polypeptide has a molecular weight (63000) and an amino acid composition similar to those of vertebrate intermediate filament proteins, including mammalian lens vime...
journal_title：Current eye research
pub_type： 杂志文章
doi：10.3109/02713688208996358
更新日期：1982-01-01 00:00:00
