Cirrus high-definition optical coherence tomography versus spectral optical coherence tomography/scanning laser ophthalmoscopy in the diagnosis of glaucoma.

abstract：PURPOSE:To evaluate how corneal deturgescence after Descemet membrane endothelial keratoplasty (DMEK) influences the posterior corneal surface area and the endothelial cell density (ECD) measurements. MATERIALS AND METHODS:A mathematical model was formulated to estimate the increase in posterior corneal surface area a...

journal_title：Current eye research

authors： Quilendrino R,Höhn H,Tse WH,Chi H,Dapena I,Ham L,Oellerich S,Melles GR

更新日期：2013-02-01 00:00:00

abstract：:In an earlier study we isolated three cyanogen bromide cleavage fragments of bovine IRBP that exhibited high levels of immunopathogenicity, producing inflammatory changes in the eyes (EAU) and pineal gland (EAP) of Lewis rats. These fragments have been localized within the IRBP sequence. In order to identify these put...

journal_title：Current eye research

authors： Sanui H,Redmond TM,Hu LH,Kuwabara T,Margalit H,Cornette JL,Wiggert B,Chader GJ,Gery I

更新日期：1988-07-01 00:00:00

abstract：:Calpains are calcium-activated proteinases which have been implicated in tissue differentiation and degeneration. The aims of the present study were: (1) to determine the relationship between postnatal age and calpain activity in the rat retina; (2) to test if calpain activity was aberrant in the RCS retina at differe...

journal_title：Current eye research

authors： Azarian SM,Williams DS

更新日期：1995-08-01 00:00:00

abstract：PURPOSE:To determine, by a plaque reduction assay, the in vitro efficacy of novel antiviral agents in the treatment of feline herpes virus 1 (FHV-1) keratitis in the domestic cat (Felis felis). MATERIALS AND METHODS:A standard plaque reduction assay was performed using a laboratory strain of FHV-1 and embryo-derived f...

journal_title：Current eye research

authors： Williams DL,Fitzmaurice T,Lay L,Forster K,Hefford J,Budge C,Blackmore K,Robinson JC,Field HF

更新日期：2004-08-01 00:00:00

abstract：:A major glycoprotein of relative molecular weight of 130,000 daltons of chick lens cell membranes was identified by Concanavalin-A staining and enriched for by Con A-Sepharose chromatography. Using both Con A binding and immunological analyses with a specific polyclonal antibody, the glycoprotein was detected in chick...

journal_title：Current eye research

authors： Heslip J,Bagchi M,Zhang S,Alousi S,Maisel H

更新日期：1986-12-01 00:00:00

abstract：PURPOSE:We located immunohistochemically the matrix metalloproteinases (MMP) -1, -2, -3 and -9 and the tissue inhibitors of matrix metalloproteinases (TIMP) -1 and -2 in the fibrous capsule of patients with intraocular lenses (IOLs). METHODS:During vitreoretinal surgery in 10 patients we obtained post-cataract surgery...

journal_title：Current eye research

authors： Kawashima Y,Saika S,Miyamoto T,Yamanaka O,Okada Y,Tanaka S,Ohnishi Y

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:This work compares the concentration of active ingredients and preservatives in commonly used brand name versus generic glaucoma medications. MATERIALS AND METHODS:Active ingredient and benzalkonium chloride (BAK) concentrations in brand name latanoprost and dorzolamide-timolol were each compared to two gen...

journal_title：Current eye research

authors： Kahook MY,Fechtner RD,Katz LJ,Noecker RJ,Ammar DA

更新日期：2012-02-01 00:00:00

abstract：PURPOSE:To study the efficacy and outcomes of short-term postoperative vitreoretinal tamponade with perfluorocarbon heavy liquid in patients with giant retinal tear. MATERIALS AND METHODS:The study group consisted of 13 consecutive patients (13 eyes) who presented with giant retinal tear at a tertiary medical center i...

journal_title：Current eye research

authors： Eiger-Moscovich M,Gershoni A,Axer-Siegel R,Weinberger D,Ehrlich R

更新日期：2017-07-01 00:00:00

abstract：:Four groups of BALB/c mice were treated locally with different concentrations (0.1-1.0%) of retinoic acid (Etretinate) ointment for a period of one to four weeks. A fifth group was treated with the ointment base only. Ia-positive dendritic cells were identified by an indirect immunofluorescence technique which was con...

journal_title：Current eye research

authors： Kremer I,Gabai U,Arbizo M,Arbizo V,Laibson PR

更新日期：1995-03-01 00:00:00

abstract：PURPOSE:To evaluate the effect of gatifloxacin ophthalmic solution 0.3% (Zymar, Allergan, Inc., Irvine, CA, USA) on corneal endothelial cell density and morphology and to measure gatifloxacin penetration into aqueous humor. METHODS:This was a single-center, open-label clinical study. Ten patients undergoing standard c...

journal_title：Current eye research

authors： Price MO,Quillin C,Price FW Jr

更新日期：2005-07-01 00:00:00

abstract：:Corneas and tendons dissected from 17-day-old chick embryos were labeled with [35S]methionine in the presence of 0.3 mM alpha,alpha'-dipyridyl. The unhydroxylated, 35S-labeled pro alpha chains and alpha chains were isolated by polyacrylamide gel electrophoresis in sodium dodecyl sulfate. The pro alpha and alpha chains...

journal_title：Current eye research

authors： Kao WW

更新日期：1985-02-01 00:00:00

abstract：PURPOSE:Androgens are thought to play a role in the regulation of the human lacrimal gland. Androgen receptor mRNA has been isolated from human lacrimal tissue; however, it is not known which cell(s) in human lacrimal tissue may contain androgen receptors. This study is an immunohistochemical investigation of the locat...

journal_title：Current eye research

authors： Smith RE,Taylor CR,Rao NA,Young LL,Rife LL

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:Aqueous extract of Pleurotus tuberregium (PT) has been shown to reduce intraocular pressure (IOP) but the underlying mechanism has not been explained. PURPOSE:To investigate the effect of PT on the bovine iris in vitro in comparison with acetylcholine (ACh). METHOD:Strips of the iris were mounted in 10 ml ...

journal_title：Current eye research

authors： Akinlabi GA,Asowata OE,Ozolua RI,Akpaja OO,Iyawe V

更新日期：2013-03-01 00:00:00

abstract：:Cytoskeletal and membrane proteins were isolated from respectively the urea-soluble and urea-insoluble fractions of the squid lens. The main cytoskeletal polypeptide has a molecular weight (63000) and an amino acid composition similar to those of vertebrate intermediate filament proteins, including mammalian lens vime...

journal_title：Current eye research

authors： Siezen RJ

更新日期：1982-01-01 00:00:00

abstract：:Although patients with diabetic retinopathy have been reported to have elevated vitreal IGF-I levels, it is not known whether diabetes also affects the levels of vitreal IGF binding proteins (IGFBPs) which control IGF's bioavailability. To address this issue, vitreal IGFBP levels were assayed in human diabetics, rats ...

journal_title：Current eye research

authors： Waldbillig RJ,Jones BE,Schoen TJ,Moshayedi P,Heidersbach S,Bitar MS,van Kuijk FJ,de Juan E,Kador P,Chader GJ

更新日期：1994-07-01 00:00:00

abstract：PURPOSE:To evaluate the predictive association between the horizontal anterior chamber diameter (HACD) and other measurements using Scheimpflug imaging, and to assess whether a method superior to using fixed constants can be proposed. METHODS:This hospital-based study was performed in the Cornea and Refractive Surgery...

journal_title：Current eye research

authors： Prakash G,Philip R,Bacero R,Srivastava D

更新日期：2017-01-01 00:00:00

abstract：PURPOSE:The purposes of this study were to investigate the effects of topically administrated Tacrolimus and Octreotide on modulation of postoperative scarring in experimental glaucoma filtration surgery and to compare the antifibrotic properties of these agents with mitomycin-C (MMC). MATERIAL AND METHODS:A total of ...

journal_title：Current eye research

authors： Arslan S,Aydemir O,Güler M,Dağlı AF

更新日期：2012-03-01 00:00:00

abstract：PURPOSE:To compare the antiviral effect of a peptide derived from human apolipoprotein E (1% apoEdp) with 1% trifluorothymidine against HSV-1 thymidine kinase (TK)-positive (HSV-1 McKrae) and with 3% foscarnet against HSV-1 TK-negative (KOS background) in the rabbit eye model of acute HSV-1 epithelial keratitis. MATER...

journal_title：Current eye research

authors： Bhattacharjee PS,Neumann DM,Hill JM

更新日期：2009-02-01 00:00:00

abstract：PURPOSE:Previous studies have suggested that corneal fibrosis controlled by a TGFbeta-mediated cytocrine pathway underlies the development of clinical corneal haze and associated regression of photoablative effect following excimer laser PRK. Using a unique blocking antibody, we evaluated the role of TGFbeta in post-PR...

journal_title：Current eye research

authors： Møller-Pedersen T,Cavanagh HD,Petroll WM,Jester JV

更新日期：1998-07-01 00:00:00

abstract：PURPOSE:To investigate retinal imaging and ablation using femtosecond laser pulses. MATERIALS AND METHODS:Two non-amplified near-infrared femtosecond lasers were used to irradiate porcine retinal specimens in vitro. The lasers were used for tissue removal as well as multiphoton laser scanning microscopy. RESULTS:Abla...

journal_title：Current eye research

authors： Hild M,Krause M,Riemann I,Mestres P,Toropygin S,Löw U,Brückner K,Seitz B,Jonescu-Cuypers C,König K

更新日期：2008-04-01 00:00:00

abstract：PURPOSE:To evaluate the inhibitory effect of human fetal retinal pigment epithelium (HFRPE) on the activation of human T-cells. METHODS:Pure cultures of HFRPE cells were incubated with purified human T-cells in three different activation assays: 1) allogenic peripheral blood mononuclear cells; 2) OKT3 coated beads in ...

journal_title：Current eye research

authors： Rezai KA,Semnani RT,Farrokh-Siar L,Hamann KJ,Patel SC,Ernest JT,van Seventer GA

更新日期：1999-06-01 00:00:00

abstract：:The present study was aimed to demonstrate that cytochrome P-450 was induced by drug administration in particular tissues in the eye. Phenobarbital was used as an inducer. We showed immunohistochemically that cytochrome P-450 was induced in the cornea, conjunctiva and ciliary epithelium of rabbits after four days of i...

journal_title：Current eye research

authors： Matsumoto K,Kishida K,Manabe R,Sugiyama T

更新日期：1987-07-01 00:00:00

abstract：PURPOSE:There is limited information on region-specific gene expression in the human corneal stroma. In this study, we aimed to investigate the expression profile of the extracellular matrix and adhesion molecules in the normal corneal stroma using laser capture microdissection (LCM) and molecular techniques. METHODS:...

journal_title：Current eye research

authors： Liu Y,Huang H,Sun G,Alwadani S,Semba RD,Lutty GA,Yiu S,Edward DP

更新日期：2017-04-01 00:00:00

abstract：:Purpose: To determine the prevalence of posterior segment manifestations among consecutive patients with pathological myopia attending our University Hospital general ophthalmology clinic and their association with age, refractive error, axial length and each other. Methods: Patients diagnosed with pathological myopia...

journal_title：Current eye research

authors： Elnahry AG,Khafagy MM,Esmat SM,Mortada HA

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:The effects of several serotonergic agonists on aqueous humor formation (AHF), total outflow facility (OF) and intraocular pressure (IOP) were investigated in living cynomolgus monkeys. METHODS:We determined the effect of a single topical unilateral 300 microg or 3 mg dose of the 5-HT agonists serotonin, 5-car...

journal_title：Current eye research

authors： Gabelt BT,Millar CJ,Kiland JA,Peterson JA,Seeman JL,Kaufman PL

更新日期：2001-08-01 00:00:00

abstract：:Importance: To analyze the characteristics and risk factors for pupillary capture (PC) of the intraocular lens (IOL) in congenital ectopia lentis (CEL) patients.Methods: Data of CEL patients who underwent lens extraction and intraocular implantation from 2013 to 2016 at Zhongshan Ophthalmic Center in China were collec...

journal_title：Current eye research

authors： Jin G,Lin J,Xiao B,Chen A,Young CA,Zheng D

更新日期：2020-04-01 00:00:00

abstract：:Antifibrosis agents have improved the success of glaucoma filtration surgery, although undesired side effects are not readily reversible and may present a major limitation in the use of these agents. Our purpose was to study the efficacy of cytosine arabinoside (Ara-C) as an adjunctive antimetabolite in glaucoma surge...

journal_title：Current eye research

authors： Chu JL,Shields SR,Netland PA

更新日期：1994-11-01 00:00:00

abstract：PURPOSE:The purpose of the current study is to assess changes in the expression of Acid-Sensing Ion Channel (ASIC)1a and ASIC2 in retinal ganglion cells (RGCs) after retinal ischemia and reperfusion (I/R) injury and to test if inhibition of ASIC1a provides RGC neuroprotection. METHODS:Transient ischemia was induced in...

journal_title：Current eye research

authors： Dibas A,Millar C,Al-Farra A,Yorio T

更新日期：2018-07-01 00:00:00

abstract：PURPOSE:To analyze the effect of diamidines (hexamidine-diisethionat (HD), propamidin-isethionate (PD), dibromopropamidine-diisethionat (DD)), and biguanides (polyhexamethylen biguanid (PHMB), chlorhexidine (CH)) on human corneal epithelial cell, keratocyte and endothelial cell viability, proliferation, and migration, ...

journal_title：Current eye research

authors： Shi L,Stachon T,Seitz B,Wagenpfeil S,Langenbucher A,Szentmáry N

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:To characterize the effects that mode of sampling and overnight eye closure have on the nature of caseinolytic activity recovered in tear fluid. METHODS:Reflex, open and closed (R, O and C) eye tear fluids were collected by microcapillary tubes or from the inferior formix by Schirmer strip. Microcapillary coll...

journal_title：Current eye research

authors： Sakata M,Sack RA,Sathe S,Holden B,Beaton AR

更新日期：1997-08-01 00:00:00