Effects of serotonergic compounds on aqueous humor dynamics in monkeys.

abstract：:Thyroxine-treated human lens epithelial cells, HLE B-3, were grown in either a normoxic or hyperoxic atmosphere as a first step in identifying factors related to their increased viability. Reactive oxygen species, ROS, and the apparent mitochondrial membrane potential, Delta Psi(m), were measured using fluorescent pro...

journal_title：Current eye research

authors： Huang L,Yappert MC,Jumblatt MM,Borchman D

更新日期：2008-07-01 00:00:00

abstract：:Purpose: To map the time course of changes in intraocular straylight of the human eye 1 year after initial lens wearing for orthokeratology treatment using the objective double-pass technique. Materials and Methods: A total of 35 subjects (19 males and 16 females) completed the study. The mean age was 11.46 ± 2.33 yea...

journal_title：Current eye research

authors： Liu G,Jin N,Bi H,Du B,Gu T,Zhang B,Wei R

更新日期：2019-01-01 00:00:00

abstract：:Perturbations in capillary endothelial cell function are early events in the pathogenesis of diabetic retinopathy. We used tritiated thymidine autoradiography to study the turn-over rate of retinal capillary endothelial cells in retinovascular preparations from normal, untreated diabetic and diabetic mice treated with...

journal_title：Current eye research

authors： Cuthbertson RA,Mandel TE

更新日期：1989-07-01 00:00:00

abstract：PURPOSE:To determine the roles of the murine interleukin-8 receptor homolog (mIL-8Rh, neutrophil chemokine CXC receptor 2) and macrophage inflammatory protein-1alpha (MIP-1alpha, a CC chemokine) in two eye inflammation models: endotoxin-induced uveitis (EIU) and immune complex-induced uveitis (reverse passive Arthus re...

journal_title：Current eye research

authors： Brito BE,O'Rourke LM,Pan Y,Huang X,Park JM,Zamora D,Cook DN,Planck SR,Rosenbaum JT

更新日期：1999-07-01 00:00:00

abstract：:A major glycoprotein of relative molecular weight of 130,000 daltons of chick lens cell membranes was identified by Concanavalin-A staining and enriched for by Con A-Sepharose chromatography. Using both Con A binding and immunological analyses with a specific polyclonal antibody, the glycoprotein was detected in chick...

journal_title：Current eye research

authors： Heslip J,Bagchi M,Zhang S,Alousi S,Maisel H

更新日期：1986-12-01 00:00:00

abstract：:Fresh isolates of neonatal human corneal endothelial cells were maintained in tissue culture using a technique employing collagen-coated, dextran-based microcarrier beads. This method provides large yields of endothelial cells suitable for biochemical and/or transplant studies without exposing the cells to enzymatic p...

journal_title：Current eye research

authors： Insler MS,Lopez JG

更新日期：1990-01-01 00:00:00

abstract：PURPOSE:To investigate the association of nailfold capillaroscopy, heart rate variability (HRV), and clinical characteristics of glaucoma with the plasma matrix metalloproteinase-9 (MMP-9) level in normal-tension glaucoma (NTG). MATERIALS AND METHODS:We conducted a prospective, cross-sectional study on 25 patients wit...

journal_title：Current eye research

authors： Lee NY,Park HY,Park SH,Park CK

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To investigate the effect of topical iganidipine, a new dihydropyridine derivative calcium channel blocker, on impairment of the ocular circulation caused by endothelin-1 (ET-1), we examined modification of the effect of ET-1 on visual-evoked potential (VEP) in albino rabbits. METHODS:To clarify whether VEP co...

journal_title：Current eye research

authors： Oku H,Sugiyama T,Kojima S,Watanabe T,Ikeda T

更新日期：2000-02-01 00:00:00

abstract：PURPOSE:To study whether there exists a relationship between retinal nerve fiber layer thickness and oxygen saturation and to identify whether perivascular thickness (pRNFL) or quadrant thickness (qRNFL) has a stronger correlation. METHODS:Patients without any detectable ocular abnormality on complete ophthalmic evalu...

journal_title：Current eye research

authors： Mohan A,Dabir S,Kurian M,Shetty R,Chidambara L,Kumar RS

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:There is a substantial literature showing that the selective estrogen receptor modulator tamoxifen can block swelling-activated chloride channels, such as those in astrocytes. This study aimed to test the hypothesis that anatomic characteristics consistent with swelling may be measured within the optic nerve he...

journal_title：Current eye research

authors： Eisner A,O'Malley JP,Incognito LJ,Toomey MD,Samples JR

更新日期：2006-04-01 00:00:00

abstract：:Purpose: To compare four visual acuity (VA) scoring termination rules. Methods: A computer simulation generated 30,000 virtual patients who underwent 10 repetitions for each of four termination rules, on both the Snellen and ETDRS charts (2.4 million tests performed in total). Three termination rules focused on the sm...

journal_title：Current eye research

authors： Mimouni M,Shamir RR,Cohen AD,El-Yaniv R,Cohen MJ,Joskowicz L,Blumenthal EZ

更新日期：2019-07-01 00:00:00

abstract：:The lacrimal gland stores retinyl esters which are synthesized by the enzyme acyl CoA:retinyl acyl transferase. Retinol is released from retinyl ester reserves by retinyl ester hydrolase (REH). Since the lacrimal gland secretes retinol, this gland should also contain this enzyme. To identify bile salt-dependent REH ac...

journal_title：Current eye research

authors： Bernal DL,Ubels JL

更新日期：1992-09-01 00:00:00

abstract：PURPOSE:Membrane-associated mucins are important components of the ocular tear film. Our objective was to characterize the expression of membrane-associated mucins MUC1, MUC4, and MUC16 in healthy cornea, healthy conjunctiva, fibrovascular tissue (pannus) covering the corneal surface in limbal stem cell deficiency (LSC...

journal_title：Current eye research

authors： Pauklin M,Kakkassery V,Steuhl KP,Meller D

更新日期：2009-03-01 00:00:00

abstract：PURPOSE:Robo1, a member of the roundabout (Robo) family, serves as neuronal guidance receptors and has been reported to mediate tumor angiogenesis. In this study, we investigated the function of Robo1 and its possible role in retinal angiogenesis in vitro and in vivo. METHODS:Expression of Robo1 in relation to retinal...

journal_title：Current eye research

authors： Huang L,Xu Y,Yu W,Li X,Liqun C,He X,Peiying H

更新日期：2009-12-01 00:00:00

abstract：PURPOSES:To investigate whether valproic acid (VPA) has a neuroprotective effect against ischemia/reperfusion (I/R) injury in the rat retina, and to elucidate the potential antioxidant mechanisms involved. METHODS:Adult male Wistar rats were randomly divided into four groups: sham (group A), sham plus VPA (group B), I...

journal_title：Current eye research

authors： Zhang Z,Qin X,Zhao X,Tong N,Gong Y,Zhang W,Wu X

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:The mechanism by which prostaglandin(PG)F2 alpha increases uveoscleral outflow and lowers intraocular pressure in primates is not known. In cultured human ciliary muscle cells, PGF2 alpha induces the expression of the protooncogene c-fos which is known to induce the transcription of genes such as matrix metallo...

journal_title：Current eye research

authors： Lindsey JD,Kashiwagi K,Boyle D,Kashiwagi F,Firestein GS,Weinreb RN

更新日期：1996-08-01 00:00:00

abstract：:The concentrations of hyaluronan (HA) and chondroitin sulfate (CS) in rabbit tears were determined using high performance liquid chromatography. The tears were taken from both normal eyes and eyes with a corneal epithelial defect. The concentration of CS was 7.61 times higher than that of HA in the tears of normal eye...

journal_title：Current eye research

authors： Miyauchi S,Morita M,Kuramoto K,Horie K

更新日期：1996-02-01 00:00:00

abstract：UNLABELLED:Purpose. To develop a rapid and accurate method for the quantification of reduced glutathione (GSH) and oxidized glutathione (GSSG) using micro-quantities of ocular lens. Methods. The epithelium, cortex and nucleus of the lens were separated and also the whole lens was homogenized in 3% metaphosphoric acid. ...

journal_title：Current eye research

authors： Liu S,Ansari NH,Wang C,Wang L,Srivastava SK

更新日期：1996-07-01 00:00:00

abstract：PURPOSE:To evaluate the stability of successive applanation tonometry measurements in glaucomatous eyes. METHODS:A prospective, comparative, randomized, and evaluator-masked study was conducted in a tertiary medical center. Sixty-seven patients with glaucoma attending our glaucoma clinic underwent four successive intr...

journal_title：Current eye research

authors： Gaton DD,Ehrenberg M,Lusky M,Wussuki-Lior O,Dotan G,Weinberger D,Snir M

更新日期：2010-06-01 00:00:00

abstract：PURPOSE:Maintaining mature and viable retinal pigment epithelial cells (RPE) in vitro has proven challenging. Investigating compounds that can promote RPE-viability and maturation is motivated by RPE transplantation research, the quest to understand RPE physiology, and a desire to modulate RPE in pathological states. W...

journal_title：Current eye research

authors： Khan AZ,Utheim TP,Moe MC,Aass HCD,Sapkota D,Vallenari EM,Eidet JR

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:Several procedures in cataract surgery carry the risk of high temperature increases in the capsular bag. The present study was undertaken to determine the shrinkage temperature of the human lens capsule and to investigate the effect of temperature on the mechanical behavior of the lens capsule. METHOD:Thermal-...

journal_title：Current eye research

authors： Krag S,Danielsen CC,Andreassen TT

更新日期：1998-05-01 00:00:00

abstract：:Cytoskeletal and membrane proteins were isolated from respectively the urea-soluble and urea-insoluble fractions of the squid lens. The main cytoskeletal polypeptide has a molecular weight (63000) and an amino acid composition similar to those of vertebrate intermediate filament proteins, including mammalian lens vime...

journal_title：Current eye research

authors： Siezen RJ

更新日期：1982-01-01 00:00:00

abstract：PURPOSE:To investigate the relationship between meibomian gland dysfunction (MGD) and incomplete blinking caused by cranial nerve seven (CN VII) palsy. METHODS:A prospective case series of 60 consecutive patients with unilateral CN VII palsy was evaluated for MGD. According to the House-Brackmann scale, patients were ...

journal_title：Current eye research

authors： Wan T,Jin X,Lin L,Xu Y,Zhao Y

更新日期：2016-01-01 00:00:00

abstract：:Hybridomas producing monoclonal antibodies to the retinal S antigen were obtained by fusion of spleen cells from a BALB/c mouse immunized with purified bovine S antigen and NS-1 myeloma cells. Six cloned hybridomas were selected and expanded as large scale cultures and as ascites in mice. The specificity of the antibo...

journal_title：Current eye research

authors： Faure JP,Mirshahi M,Dorey C,Thillaye B,de Kozak Y,Boucheix C

更新日期：1984-06-01 00:00:00

abstract：PURPOSE:Based on the relationship between keratoconus and dry eye, the aim of this study was to evaluate changes in signs and symptoms of dry eye in keratoconus patients before and after intrastromal corneal ring surgery. METHODS:Fifteen keratoconus patients were enrolled in Fundación Jiménez-Díaz of Madrid and Univer...

journal_title：Current eye research

authors： Carracedo G,Recchioni A,Alejandre-Alba N,Martin-Gil A,Batres L,Morote IJ,Pintor J

更新日期：2017-04-01 00:00:00

abstract：:High pressure liquid chromatography was used to measure alpha-tocopherol in the retinas of rats reared in a cyclic light or dark environment. These measurements were performed on extracts of whole retinas during the developmental period, 18-60 days, and on isolated ROS from adult animals. Similar alpha-tocopherol dete...

journal_title：Current eye research

authors： Hunt DF,Organisciak DT,Wang HM,Wu RL

更新日期：1984-11-01 00:00:00

abstract：:Purpose/Aim of the study: A recently proposed technique enables the generation of continuously increasing mosaic images of the corneal sub-basal nerve plexus (SNP) using in vivo corneal confocal microscopy (CCM). The aim of the present study was to investigate the progression of the corneal nerve fiber length (CNFL) m...

journal_title：Current eye research

authors： Allgeier S,Winter K,Bretthauer G,Guthoff RF,Peschel S,Reichert KM,Stachs O,Köhler B

更新日期：2017-04-01 00:00:00

abstract：:Purpose: To determine the refractive astigmatism following toric intraocular lens (tIOL) implantation without consideration of posterior keratometric astigmatism with a conventional tIOL calculator for eyes with low keratometric astigmatism (0.75D to 2.5D) and to theoretically compare the outcomes with predicted refra...

journal_title：Current eye research

authors： Nanavaty MA,Teeluck K,Bardan AS,Bedi KK,Ali S

更新日期：2019-12-01 00:00:00

abstract：PURPOSE:The purpose of this study was to determine the retinal expression of angiogenic chemokines/cytokines in a mouse model of oxygen-induced retinopathy. METHODS:C57BL/6 (B6) mice were exposed to 75% oxygen from postnatal day 7 (P7) to P12 and then recovered in room air. Reverse transcription-polymerase chain react...

journal_title：Current eye research

authors： Powers MR,Davies MH,Eubanks JP

更新日期：2005-04-01 00:00:00

abstract：PURPOSE/AIM OF THE STUDY:The aim of this study is to investigate the effect of pseudoexfoliation (PEX) and PEX-induced dry eye on central corneal thickness (CCT). MATERIALS AND METHODS:This cross-sectional study consists of total 270 eyes of 135 patients (67 females, 68 males) in total. After excluding the PEX (-) 32 ...

journal_title：Current eye research

authors： Akdemir MO,Kirgiz A,Ayar O,Kaldirim H,Mert M,Cabuk KS,Taskapili M

更新日期：2016-01-01 00:00:00