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The correlation between genomic G+C and optimal growth temperature of prokaryotes is robust: a reply to Marashi and Ghalanbor.

Abstract：

:We have recently shown that optimal growth temperature (T(opt)) is one of the factors that influence genomic GC in prokaryotes. Our results have been disputed by Marashi and Ghalanbor, who claim that the correlations we show are not "robust" because the elimination of some points (arbitrarily chosen) leads, in some families, to variations in the correlation coefficients and/or significance of correlations. Here, we test whether the correlation between T(opt) and genomic GC is robust by using two independent approaches: detection of possible outliers (using robust Mahalanobis distance) and usage of a non-parametric correlation coefficient that is not sensitive to the presence of outliers. The results presented here reinforce our previous proposal that T(opt) is correlated with genomic GC in prokaryotes.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Musto H,Naya H,Zavala A,Romero H,Alvarez-Valin F,Bernardi G

doi

10.1016/j.bbrc.2005.02.133

subject

Has Abstract

pub_date

2005-05-06 00:00:00

pages

357-60

issue

2

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(05)00407-9

journal_volume

330

pub_type

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