MAP kinase phosphorylation of plant profilin.

abstract：:Each chromosome occupies its own-specific space called a 'territory' within the interphase nucleus, and the arrangement of chromosome territories (CTs) is important in epigenetic mechanisms. The molecular mechanism to determine the positioning of CTs, however, remains unknown. On the other hand, dioxin is known to be ...

journal_title：Biochemical and biophysical research communications

authors： Oikawa K,Yoshida K,Takanashi M,Tanabe H,Kiyuna T,Ogura M,Saito A,Umezawa A,Kuroda M

更新日期：2008-09-19 00:00:00

abstract：:Semaphorins provide crucial attractive and repulsive cues involved in axon guidance during neural development. Out of them, Semaphorin 4D (Sema4D) is enriched in the nervous and immune tissues, and acts as proliferative and survival factors of peripheral lymphocytes in the immune system, but is poorly understood in th...

journal_title：Biochemical and biophysical research communications

authors： Fujioka S,Masuda K,Toguchi M,Ohoka Y,Sakai T,Furuyama T,Inagaki S

更新日期：2003-02-07 00:00:00

abstract：:Alveolar epithelial type II cells (ATII cells) are the main target cells being damaged and releasing the inflammatory mediators during acute respiratory distress syndrome (ARDS). Extensive apoptosis of epithelial cells leads to the breakdown of the alveolar-epithelial barrier in ARDS. Cyclooxygenase-2 (COX-2) plays an...

journal_title：Biochemical and biophysical research communications

authors： Sun J,Zheng S,Yang N,Chen B,He G,Zhu T

更新日期：2019-09-10 00:00:00

abstract：:Recent evidence suggests that untimely retinoblastoma protein (RB) dephosphorylation and/or proteolytic degradation might provide key events down-stream cysteine protease (caspase) activation in apoptosis induction. We have dealt with this issue by studying apoptosis induced by N-hexanoylsphingosine (C6-Cer) in CHP-10...

journal_title：Biochemical and biophysical research communications

authors： Spinedi A,Amendola A,Di Bartolomeo S,Piacentini M

更新日期：1998-02-24 00:00:00

abstract：:In the TT cell line of human medullary thyroid carcinoma, the viral Harvey ras (v-rasH) oncogene induces differentiation, marked by morphological changes, diminution of growth, and increased expression of the calcitonin gene. Here, we show that the transcriptional factor c-jun is increased during v-rasH induced differ...

journal_title：Biochemical and biophysical research communications

authors： Nelkin BD,Borges M,Mabry M,Baylin SB

更新日期：1990-07-16 00:00:00

abstract：:Colorectal cancer is one of the leading causes of cancer-related deaths. Due to relapse after current therapy regimens, cancer stem cells (CSCs) are being studied to target this small tumor-initiating population. Anterior gradient 2 (AGR2), a disulfide isomerase protein, is a well-known pro-oncogenic/metastatic oncoge...

journal_title：Biochemical and biophysical research communications

authors： Dahal Lamichane B,Jung SY,Yun J,Kang S,Kim DY,Lamichane S,Kim YJ,Park JH,Jang WB,Ji ST,Dehua L,Ha JS,Kim YH,Kwon SM

更新日期：2019-08-06 00:00:00

abstract：:Microinjection of inositol 1,3,4,5-tetrakisphosphate or inositol 1,4,5-trisphosphate induced distinct chloride membrane currents in defolliculated Xenopus laevis oocytes. To decide whether these Cl(-)-currents were due to the injected compounds or their metabolic products, [3H]Ins(1,3,4,5)P4 or [3H]Ins(1,4,5)P3 were i...

journal_title：Biochemical and biophysical research communications

authors： Guse AH,Gercken G,Boysen H,Schwarz JR,Meyerhof W

更新日期：1991-08-30 00:00:00

abstract：:Human monocarboxylate transporters (hMCTs) mediate the transport of monocarboxylates across plasma membranes. One such transporter, hMCT9, has been shown to be related to serum uric acid levels and the risk of renal overload gout. However, the functional characteristics of hMCT9 remain unknown. The aim of this study w...

journal_title：Biochemical and biophysical research communications

authors： Futagi Y,Narumi K,Furugen A,Kobayashi M,Iseki K

更新日期：2020-02-05 00:00:00

abstract：:Polyphosphoinositide hydrolysis was examined in membranes from thyrotropin-releasing hormone (TRH)-responsive GH3 pituitary cells. [3H]Inositol phosphates (IP2 and IP3) were generated upon incubation of membranes from [3H]inositol-labeled cells indicating the presence of a membrane-associated polyphosphoinositide phos...

journal_title：Biochemical and biophysical research communications

authors： Lucas DO,Bajjalieh SM,Kowalchyk JA,Martin TF

更新日期：1985-10-30 00:00:00

abstract：:ATP1B4 genes represent a rare instance of the orthologous gene co-option that radically changed functions of encoded BetaM proteins during vertebrate evolution. In lower vertebrates, this protein is a β-subunit of Na,K-ATPase located in the cell membrane. In placental mammals, BetaM completely lost its ancestral role ...

journal_title：Biochemical and biophysical research communications

authors： Pestov NB,Zhao H,Basrur V,Modyanov NN

更新日期：2011-09-09 00:00:00

abstract：:In malate dehydrogenase from Thermus flavus, substitution of Ile for Thr189, which is involved in hydrogen-bond network around a loop containing catalytic His186, caused an increase in the turnover number at room temperatures. In order to examine the effect of disruption of the hydrogen bonds on the catalytic activity...

journal_title：Biochemical and biophysical research communications

authors： Nishiyama M,Kinoshita M,Kudo H,Horinouchi S,Tanokura M

更新日期：1996-08-23 00:00:00

abstract：:The specific binding of vitronectin to Streptococcus pyogenes is believed to play an important role in the infection process by mediating adherence of the bacteria to host cells. The domain of vitronectin involved in the interaction with S. pyogenes is unknown. In the present study, we constructed a vitronectin random...

journal_title：Biochemical and biophysical research communications

authors： Liang OD,Preissner KT,Chhatwal GS

更新日期：1997-05-19 00:00:00

abstract：:Oxidative stress is widely involved in pathophysiological processes of cardiac remodeling. Molecules associated with antioxidant functions may be ideal targets for reversing cardiac remodeling. Sestrin2 is the important component of endogenous antioxidant defense, while there is little information on the pathophysiolo...

journal_title：Biochemical and biophysical research communications

authors： Du JX,Wu JZ,Li Z,Zhang C,Shi MT,Zhao J,Jin MW,Liu H

更新日期：2019-04-30 00:00:00

abstract：:A hitherto unknown synergism exerted by retinol (vitamin A) and L-ascorbic acid (vitamin C) was discovered using endothelial cells. Retinol stimulated the extracellular and intracellular activities of plasminogen activator up to approximately 8- and 4-fold from the control values, respectively. L-Ascorbic acid enhance...

journal_title：Biochemical and biophysical research communications

authors： Inada Y,Hagiwara H,Kojima S,Shimonaka M,Saito Y

更新日期：1985-07-16 00:00:00

abstract：:It has been reported that mammalian cells incubated with excess nitric oxide (NO) accumulate p53 protein but concomitantly this p53 loses its capacity for binding to its DNA consensus sequence. As nitration of tyrosine residues in various proteins has been shown to inhibit their functions, we examined whether NO nitra...

journal_title：Biochemical and biophysical research communications

authors： Chazotte-Aubert L,Hainaut P,Ohshima H

更新日期：2000-01-19 00:00:00

abstract：:The regulatory mechanisms of most cyclin dependent protein kinases (CDKs) are well understood and are highly conserved in eukaryotes. CDKs from the malaria parasite, Plasmodium falciparum, appear to be regulated in a similar manner with regard to cyclin binding and phosphorylation. In order to further understand their...

journal_title：Biochemical and biophysical research communications

authors： Li Z,Le Roch K,Geyer JA,Woodard CL,Prigge ST,Koh J,Doerig C,Waters NC

更新日期：2001-11-16 00:00:00

abstract：:Human thymidine phosphorylase (dThdPase) is thought to be identical to an angiogenesis factor, platelet-derived endothelial cell growth factor (PD-ECGF). However, the whole amino acid sequence of dThdPase is still unknown. N-terminal amino acid sequencing of dThdPase isolated from human placenta gave the sequence Ac-A...

journal_title：Biochemical and biophysical research communications

authors： Miyadera K,Dohmae N,Takio K,Sumizawa T,Haraguchi M,Furukawa T,Yamada Y,Akiyama S

更新日期：1995-07-26 00:00:00

abstract：:Isolation of pure acinar cells of the rat pancreas was achieved employing counterflow sedimentation filtration technique (CSFT). The preparation of purified acinar cells contained an occasional red blood cell (RBC, 200:1) with total absence of endocrine and duct cells. A significant stimulation of amylase secretion fr...

journal_title：Biochemical and biophysical research communications

authors： Bandisode MS,Singh M

更新日期：1985-05-31 00:00:00

abstract：:Apoptosis (APO) and necrosis (NEC) are two different types of cell death occurring in response to cellular stress factors. Cells with DNA damage may undergo APO or NEC. Folate is an essential micronutrient associated with DNA synthesis, repair and methylation. Methylenetetrahydrofolate reductase (MTHFR) regulates intr...

journal_title：Biochemical and biophysical research communications

authors： Wu X,Liang Z,Zou T,Wang X

更新日期：2009-02-13 00:00:00

abstract：:The ability of various compounds to stimulate cyclic GMP accumulation was studied in neuronal and astrocyte-enriched primary cultures from rat cerebrum. Glutamate was the only agonist eliciting a response in neurons whereas several agonists had an effect in astrocytes but only those due to norepinephrine and glutamate...

journal_title：Biochemical and biophysical research communications

authors： Agulló L,García A

更新日期：1992-02-14 00:00:00

abstract：:Wnt/beta-catenin signaling plays an important role not only in cancer, but also in cancer stem cells. In this study, we found that beta-catenin and OCT-4 was highly expressed in cisplatin (DDP) selected A549 cells. Stimulating A549 cells with lithium chloride (LiCl) resulted in accumulation of beta-catenin and up-regu...

journal_title：Biochemical and biophysical research communications

authors： Teng Y,Wang X,Wang Y,Ma D

更新日期：2010-02-12 00:00:00

abstract：:Glucose transporter-1 (GLUT1) is important in placental glucose transport. However, the mechanism of regulation of placental GLUT1 expression remains to be elucidated. We show here that the level of GLUT1 protein in rat choriocarcinoma cells (Rcho-1) decreased during differentiation. To analyze the regulatory mechanis...

journal_title：Biochemical and biophysical research communications

authors： Okamoto Y,Sakata M,Yamamoto T,Nishio Y,Adachi K,Ogura K,Yamaguchi M,Takeda T,Tasaka K,Murata Y

更新日期：2001-11-09 00:00:00

abstract：:GH3/B6 pituitary cells release prolactin (PRL) in response to thyrotropin releasing hormone (TRH). Electrophysiological assays of individual GH3 cells with sharp high-resistance microelectrodes have revealed complex effects of TRH on membrane excitability consisting of a transient hyperpolarization (1), which is thoug...

journal_title：Biochemical and biophysical research communications

authors： Dufy B,MacDermott A,Barker JL

更新日期：1986-05-29 00:00:00

abstract：:Human lung carcinoma cells (A549) were oxidatively stressed with mildly-toxic or non-toxic amounts of hydrogen peroxide (H2O2, 0.1 mM to 120 mM) for 5 min. Hydrogen peroxide exposure resulted in a dose dependent inhibition of binding (pH 7) of the thiol reagent iodoacetic acid (IAA) to a 38 kDa cell protein. Incubatio...

journal_title：Biochemical and biophysical research communications

authors： Brodie AE,Reed DJ

更新日期：1987-10-14 00:00:00

abstract：:Upon centrifugation of gently lysed T. cruzi cells through a sucrose gradient, a free DNA fraction was shown to contain catenated dimers and knotted DNA structures. Southern hybridization and electron microscopic studies indicated that both of these structures derived from minicircle DNA, the major component of T. cru...

journal_title：Biochemical and biophysical research communications

authors： Valenzuela MS,Bardhan S,Krishnamani MR,Siddiqui KA

更新日期：1991-01-31 00:00:00

abstract：:The exposure of organ cultured pineal glands of Syrian hamsters to forskolin, an adenylate cyclase activator, caused marked increases in serotonin N-acetyltransferase activity and melatonin content in a dose-related manner (1-100 microM) when glands were collected in the second half of the dark period. However, additi...

journal_title：Biochemical and biophysical research communications

authors： Santana C,Guerrero JM,Reiter RJ,Gonzalez-Brito A,Menendez-Pelaez A

更新日期：1988-08-30 00:00:00

abstract：:A sample of highly oriented Na-hyaluronate was prepared with a wet--spinning method and equilibrated to 75% relative humidity. Its proton NMR spectrum was recorded as a function of the angle theta between the hyaluronate helix axis and the external magnetic field. It appeared as a singlet with an angle-dependent line ...

journal_title：Biochemical and biophysical research communications

authors： Lahajnar G,Rupprecht A

更新日期：1986-11-26 00:00:00

abstract：:Accumulating evidence indicates that microRNAs function as oncogenes or tumor suppressor genes in human cancer. MiR-503 is deregulated in various human cancers and has been associated with hepatocellular carcinoma (HCC) progression. However, the underlying mechanisms of miR-503 involvement in the development and progr...

journal_title：Biochemical and biophysical research communications

authors： Li B,Liu L,Li X,Wu L

更新日期：2015-09-04 00:00:00

abstract：:The origins and developmental regulation of cerebellar oligodendrocytes are largely unknown, although some hypotheses of embryonic origins have been suggested. Neural stem cells exist in the white matter of postnatal cerebellum, but it is unclear whether these neural stem cells generate oligodendrocytes at postnatal s...

journal_title：Biochemical and biophysical research communications

authors： Naruse M,Shibasaki K,Ishizaki Y

更新日期：2015-08-07 00:00:00

abstract：:Six peaks of small GTP-binding proteins (G proteins) were separated by column chromatographies from the cytosol fraction of the differentiated HL-60 cells: two peaks of rho p21, one peak of smg/rap1 p21, two peaks of rac1 p21, and one peak of an unidentified small G protein with a Mr of about 20,000 (20 KG). smg GDS, ...

journal_title：Biochemical and biophysical research communications

authors： Hiraoka K,Kaibuchi K,Ando S,Musha T,Takaishi K,Mizuno T,Asada M,Ménard L,Tomhave E,Didsbury J

更新日期：1992-01-31 00:00:00