当前位置： SCI文献检索 > BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS期刊下所有文献 > Transcription factor levels in medullary thyroid carcinoma cells differentiated by Harvey ras oncogene: c-jun is increased.

Transcription factor levels in medullary thyroid carcinoma cells differentiated by Harvey ras oncogene: c-jun is increased.

Abstract：

:In the TT cell line of human medullary thyroid carcinoma, the viral Harvey ras (v-rasH) oncogene induces differentiation, marked by morphological changes, diminution of growth, and increased expression of the calcitonin gene. Here, we show that the transcriptional factor c-jun is increased during v-rasH induced differentiation of TT cells both at the mRNA and functional protein levels. In contrast, nuclear proteins with binding activities related to AP2, AP3, NF1/CTF, and Sp1 were unchanged in v-rasH differentiated TT cells.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Nelkin BD,Borges M,Mabry M,Baylin SB

doi

10.1016/0006-291x(90)91251-m

subject

Has Abstract

pub_date

1990-07-16 00:00:00

pages

140-6

issue

1

eissn

0006-291X

issn

1090-2104

pii

0006-291X(90)91251-M

journal_volume

170

pub_type

杂志文章

相关文献

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS文献大全
  • Prolactin receptor regulation by LH in the rat mammary gland.

    abstract：:The aim of this study was to investigate hormonal factors responsible for the huge increase in PRL receptors on the day of estrus in the rat mammary gland. For this purpose, ovariectomized rats were primed with E2 so as to reach a physiological serum concentration of E2 (21.5 +/- 1.2 pg/ml) and high PRL serum values (...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(86)91038-7

    authors： Guillaumot P,Sabbagh I,Bertrand J,Cohen H

    更新日期：1986-03-28 00:00:00

  • Difference of hyaluronidase produced by human tumor cell lines with hyaluronidase present in human serum as revealed by zymography.

    abstract：:Human carcinoma cells cultured in serum free medium produced an enzyme present as two different isoforms of 62 and 59 kDa which was found to degrade hyaluronan and chondroitin sulfate, with optimum activity at pH 4.0 and 0.03 M NaCl. The activity was suppressed by treatment with 250 mM apigenin and 1 mM DTT. The one-d...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1997.7829

    authors： Podyma KA,Yamagata S,Sakata K,Yamagata T

    更新日期：1997-12-18 00:00:00

  • Wild-type and mutated nicastrins do not display aminopeptidase M- and B-like activities.

    abstract：:Nicastrin is a recently discovered protein interacting with presenilins and the beta-amyloid precursor protein, the proteins playing key roles in Alzheimer's disease and which, when mutated, appear responsible for early-onset familial forms of Alzheimer's disease. Nicastrin was reported to modulate beta-amyloid produc...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2001.6030

    authors： Fergani A,Yu G,St George-Hyslop P,Checler F

    更新日期：2001-12-07 00:00:00

  • Interaction between phosphoinositide turnover system and cyclic AMP pathway for the secretion of pancreastatin and somatostatin from QGP-1N cells.

    abstract：:It is found that secretion of pancreastatin and somatostatin from QGP-1N cells is regulated through muscarinic receptor-mediated activation of phosphatidylinositide hydrolysis system. In this report, whether the cAMP pathway interacts with the phosphoinositide turnover system for the secretion of pancreastatin and som...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(92)91731-5

    authors： Tateishi K,Funakoshi A,Kitayama N,Matsuoka Y

    更新日期：1992-06-30 00:00:00

  • Activation of p38 MAPK induces cell cycle arrest via inhibition of Raf/ERK pathway during muscle differentiation.

    abstract：:Cell cycle arrest is essential for initiation of muscle differentiation in myoblasts. Given the previously described essential role for p38 MAPK in myogenesis, we undertook the present study to investigate the role of p38 MAPK in the cell cycle arrest that initiates muscle differentiation. p38 MAPK activity increased ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(02)02562-7

    authors： Lee J,Hong F,Kwon S,Kim SS,Kim DO,Kang HS,Lee SJ,Ha J,Kim SS

    更新日期：2002-11-15 00:00:00

  • Functional interaction of the immunosuppressant mizoribine with the 14-3-3 protein.

    abstract：:Mizoribine (MIZ) is a novel imidazole nucleoside with immunosuppressive activity. MIZ has been approved in Japan and combination therapy with MIZ and glucocorticoids has been used after renal transplantation and for lupus nephritis and rheumatoid arthritis. In this study, we identify 14-3-3 proteins as MIZ-binding pro...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2000.3104

    authors： Takahashi S,Wakui H,Gustafsson JA,Zilliacus J,Itoh H

    更新日期：2000-07-21 00:00:00

  • Nucleotide sequence of a bovine lens alpha A-crystallin cDNA.

    abstract：:We have determined the nucleotide sequence of a bovine lens alpha A2-crystallin cDNA clone, designated pBL alpha A2-1. The 793 bp cDNA insert contains coding information for the entire 173 amino acid alpha A2-crystallin polypeptide, as well as non-translated sequences located both upstream and downstream from the codi...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(87)91072-2

    authors： Hay RE,Petrash JM

    更新日期：1987-10-14 00:00:00

  • Calmodulin-dependent phosphorylation and dephosphorylation during fertilization in Dictyostelium discoideum.

    abstract：:Many calmodulin-dependent biological phenomena are regulated by calmodulin-dependent phosphorylation and dephosphorylation. In Dictyostelium discoideum, cell and pronuclear fusion during fertilization are both calmodulin-dependent biomembrane fusion events. Calmodulin-dependent phosphorylation and dephosphorylation ac...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1993.1526

    authors： Lydan MA,O'Day DH

    更新日期：1993-05-14 00:00:00

  • Ornithine transcarbamylase deficiency in spf and spf-ash mice: genes, mRNAs and mRNA precursors.

    abstract：:Two ornithine transcarbamylase-deficient mice are available, the spf with a variant enzyme and spf-ash with a markedly decreased enzyme protein. Genomic DNA, mRNA and the nuclear precursors for the enzyme in these mutants were analyzed. Southern blot analysis of genomic DNA showed no abnormality in the mutant mice. Bl...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(87)90755-8

    authors： Ohtake A,Takayanagi M,Yamamoto S,Nakajima H,Mori M

    更新日期：1987-08-14 00:00:00

  • Absence of short-term regulation over gluconeogenesis by glucose in the insect Manduca sexta L.

    abstract：:In vivo gluconeogenesis from (3-13 C)alanine was evident in terminal instar Manduca sexta larvae from the selective fractional 13C enrichment in trehalose, a disaccharide of glucose and the major blood sugar of insects. De novo glucose synthesis was observed in insects fed a low carbohydrate diet for 1 or more days. G...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1997.7211

    authors： Thompson SN

    更新日期：1997-08-28 00:00:00

  • Role of N-myristoylation in stability and subcellular localization of the CLPABP protein.

    abstract：:Cardiolipin and phosphatidic acid-binding protein (CLPABP) controls the stability of the mRNA harboring an AU-rich element (ARE) in the 3' UTR with the help of the RNA stabilizer, human antigen R (HuR). Although CLPABP is localized on the mitochondrial surface as a large protein-RNA complex, its precise role is not ye...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2017.11.112

    authors： Maeda A,Uchida M,Nishikawa S,Nishino T,Konishi H

    更新日期：2018-01-01 00:00:00

  • Isolation and characterization of four basic proteins from horse eosinophilic granules.

    abstract：:Four new basic proteins were isolated from horse eosinophils and purified. The eosinophils release these proteins after permeabilization with saponin and degranulation stimulized by guanosine 5'-O-thiotriphosphate. The proteins were separated and purified on a Superose P12- and a Mono S-column by fast protein liquid c...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1993.1425

    authors： Piller K,Portmann P

    更新日期：1993-04-30 00:00:00

  • Monoclonal antibodies to low density lipoprotein used for the study of low- and very-low-density lipoproteins, in "ELISA" and immunoprecipitation technics.

    abstract：:Seven monoclonal antibodies to low-density lipoprotein were studied by the ELISA for their reactivity with LDL or VLDL. Cotitration experiments showed that five of them are addressed to different antigenic epitopes. Two of the monoclonal antibodies were temperature independent whereas the others had a decreased bindin...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(84)90596-5

    authors： Salmon S,Goldstein S,Pastier D,Theron L,Berthelier M,Ayrault-Jarrier M,Dubarry M,Rebourcet R,Pau B

    更新日期：1984-12-14 00:00:00

  • Antisense RNA to the first N-glycosylation gene, ALG7, inhibits protein N-glycosylation and secretion by Xenopus oocytes.

    abstract：:N-Glycosylation has been shown to affect the rate of glycoprotein transport through the secretory pathway. In order to identify the critical components in the N-glycosylation pathway that directly influence protein secretion, we have studied the effects of downregulation of the first gene in the dolichol pathway, ALG7...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1994.1176

    authors： Kukuruzinska MA,Apekin V,Lamkin MS,Hiltz A,Rodriguez A,Lin CC,Paz MA,Oppenheim FG

    更新日期：1994-02-15 00:00:00

  • Long noncoding RNA LINC00339 aggravates doxorubicin-induced cardiomyocyte apoptosis by targeting MiR-484.

    abstract：:Abnormally expressed long noncoding RNAs (lncRNAs) has been recognized as one of the key source in cardiac diseases. However, the role of lncRNA in doxorubicin (DOX)-induced cardiotoxicity remains largely unknown. In previous studies, we have screened some aberrantly expressed lncRNAs from an animal model for DOX-indu...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2018.08.090

    authors： Li J,Li L,Li X,Wu S

    更新日期：2018-09-18 00:00:00

  • Antiproliferative effect of 1,25-dihydroxyvitamin D3 and its analogs on human colon adenocarcinoma cells (CaCo-2): influence of extracellular calcium.

    abstract：:Depending on culture in either "low Ca++" (0.25 mM) or "normal Ca++" (1.8 mM) medium, human colon adenocarcinoma-derived CaCo-2 cells exhibit differential sensitivity to the antiproliferative action of 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) and of two side-chain modified analogs, 1,25S,26-trihydroxy-delta 22-vitamin D...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(91)91333-8

    authors： Cross HS,Huber C,Peterlik M

    更新日期：1991-08-30 00:00:00

  • Ubiquitination of specific mitochondrial matrix proteins.

    abstract：:Several protein quality control systems in bacteria and/or mitochondrial matrix from lower eukaryotes are absent in higher eukaryotes. These are transfer-messenger RNA (tmRNA), The N-end rule ATP-dependent protease ClpAP, and two more ATP-dependent proteases, HslUV and ClpXP (in yeast). The lost proteases resemble the...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2016.04.150

    authors： Lehmann G,Ziv T,Braten O,Admon A,Udasin RG,Ciechanover A

    更新日期：2016-06-17 00:00:00

  • D-ribose inhibits DNA repair synthesis in human lymphocytes.

    abstract：:D-ribose is cytotoxic for quiescent human lymphocytes and severely inhibits their PHA-induced proliferation at concentrations (25-50 mM) at which other simple sugars are ineffective. In order to explain these effects, DNA repair synthesis was evaluated in PHA-stimulated human lymphocytes treated with hydroxyurea and i...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(86)80549-6

    authors： Zunica G,Marini M,Brunelli MA,Chiricolo M,Franceschi C

    更新日期：1986-07-31 00:00:00

  • CDw 60 antibodies bind to acetylated forms of ganglioside GD3.

    abstract：:Four monoclonal antibodies, M-T21, M-T32, M-T41 and UM4D4, which belong to the new CDw 60 cluster of antibodies specific for a subpopulation of human T-lymphocytes, were found to bind mainly to acetylated forms of ganglioside GD3. After O-deacetylation of the antigen, binding was reduced ("M-T"-antibodies) or abolishe...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(92)90450-y

    authors： Kniep B,Peter-Katalinić J,Flegel W,Northoff H,Rieber EP

    更新日期：1992-09-30 00:00:00

  • Diglyceride/monoglyceride lipases pathway is not essential for arachidonate release in thrombin-activated human platelets.

    abstract：:Human platelets prelabeled with arachidonate exhibited a rapid and transient rise in arachidonoyl monoglyceride in addition to arachidonoyl diglyceride following thrombin stimulation. Substantial release of arachidonate and its metabolites also occurred at the early phase. Preincubation of labeled platelets with RHC 8...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(83)90457-6

    authors： Chau LY,Tai HH

    更新日期：1983-05-31 00:00:00

  • MicroRNA-501 promotes HBV replication by targeting HBXIP.

    abstract：:MicroRNAs (miRNAs) can negatively regulate gene expression and also induce or inhibit viral replication. In the present study, we found 10 miRNAs were differentially expressed in a stable HBV-producing cell line (HepG2.2.15) compared with its control cell line (HepG2) by miRNA array analysis. miR-501 was significantly...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2012.12.071

    authors： Jin J,Tang S,Xia L,Du R,Xie H,Song J,Fan R,Bi Q,Chen Z,Yang G,Liu J,Shi Y,Fan D

    更新日期：2013-01-25 00:00:00

  • Metabolism of lipoxins A4 and B4 and of their all-trans isomers by human leukocytes and rat liver microsomes.

    abstract：:Incubation of lipoxin A4 (LXA4) either with human leukocytes or with rat liver microsomes in the presence of NADPH very selectively led to a more polar metabolite retaining the conjugated tetraenic structure of LXA4. Lipoxin B4 (LXB4) underwent a very similar metabolism into a more polar metabolite, whereas the all-tr...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(91)91958-f

    authors： Boucher JL,Delaforge M,Mansuy D

    更新日期：1991-05-31 00:00:00

  • Pillar cell and erythrocyte localization of fugu ET(A) receptor and its implication.

    abstract：:Endothelin, a vasoconstrictor peptide, plays important roles not only in the mammalian circulatory system but also in non-mammalian systems, such as the gill lamellar vascular network with complex structural characteristics. Here, we show that (i) the contraction of pillar cells that delimit the lamellar vasculature i...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2007.01.128

    authors： Sultana N,Nag K,Kato A,Hirose S

    更新日期：2007-03-30 00:00:00

  • A missense mutation in the RING finger motif of PEX2 protein disturbs the import of peroxisome targeting signal 1 (PTS1)-containing protein but not the PTS2-containing protein.

    abstract：:SK24 and PT54 mutant cells, which are peroxisome-deficient Chinese hamster ovary (CHO) cells isolated using peroxisomal forms of green fluorescent protein (GFP), were found to be defective in the PEX2 gene. The nucleotide sequences of PEX2 cDNA from the mutant cells were determined to identify mutation sites in the mu...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.2000.2510

    authors： Huang Y,Ito R,Miura S,Hashimoto T,Ito M

    更新日期：2000-04-21 00:00:00

  • Two splice variants of CaMKII-anchoring protein are present in the sarcoplasmic reticulum of rabbit fast-twitch muscle.

    abstract：:Anchoring protein alphaKAP targets calmodulin kinase II (CaMKII) to the sarcoplasmic reticulum (SR), and in the rabbit is a substrate of CaMKII itself in fast-twitch, but not in slow-twitch muscle. This work was aimed at elucidating the molecular basis for differential phosphorylation of alphaKAP. Here we show that tw...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(03)00110-4

    authors： Damiani E,Sacchetto R,Salviati L,Margreth A

    更新日期：2003-02-28 00:00:00

  • Glucose-induced glutathione reduction in mitochondria is involved in the first phase of pancreatic β-cell insulin secretion.

    abstract：:Glucose can acutely reduce mitochondrial glutathione redox state in rat islets. However, whether glucose-stimulated mitochondrial glutathione redox state relates to glucose-stimulated insulin secretion (GSIS) remains unknown. We used genetically encoded redox-sensitive GFPs to target the mitochondria to monitor glutat...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2015.07.016

    authors： Liu X,Han S,Yang Y,Kang J,Wu J

    更新日期：2015-08-28 00:00:00

  • Dynamics of catalysis revealed from the crystal structures of mutants of diaminopimelate epimerase.

    abstract：:Diaminopimelate (DAP) epimerase catalyzes the stereoinversion of ll-DAP to meso-DAP, a precursor of l-lysine and an essential component of the bacterial peptidoglycan. This function is vital to bacteria and the enzyme therefore represents an attractive target for the design of novel anti-bacterials. DAP epimerase belo...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2007.09.012

    authors： Pillai B,Cherney M,Diaper CM,Sutherland A,Blanchard JS,Vederas JC,James MN

    更新日期：2007-11-23 00:00:00

  • An inhibitor of c-Jun N-terminal kinases (CEP-11004) counteracts the anti-HIV-1 action of trichosanthin.

    abstract：:Trichosanthin (TCS) is a type I ribosome-inactivating protein possessing multiple biological and pharmacological activities. One of its major actions is inhibition of human immunodeficiency virus (HIV) replication. The mechanism is still not clear. It is generally believed that this action is mediated via ribosome ina...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2005.11.004

    authors： Ouyang DY,Chan H,Wang YY,Huang H,Tam SC,Zheng YT

    更新日期：2006-01-06 00:00:00

  • DGKζ is involved in LPS-activated phagocytosis through IQGAP1/Rac1 pathway.

    abstract：:Diacylglycerol kinase (DGK) plays an important role in phosphoinositide signaling cascade by regulating the intracellular level of diacylglycerol and phosphatidic acid. The DGK family is involved in various pathophysiological responses that are mediated through unique binding partners in different tissues and cells. I...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2012.03.057

    authors： Okada M,Hozumi Y,Iwazaki K,Misaki K,Yanagida M,Araki Y,Watanabe T,Yagisawa H,Topham MK,Kaibuchi K,Goto K

    更新日期：2012-04-06 00:00:00

  • Distinct distributions of mu, delta and kappa opioid receptor mRNA in rat brain.

    abstract：:We present a comprehensive comparison of the anatomical distributions of the cloned mu, delta and kappa opioid receptor mRNA in rat brain. Northern blot analysis revealed that mRNA species encoding the three receptors differed in size and were differentially localized in brain regions. In peripheral tissues analyzed, ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1994.2826

    authors： George SR,Zastawny RL,Briones-Urbina R,Cheng R,Nguyen T,Heiber M,Kouvelas A,Chan AS,O'Dowd BF

    更新日期：1994-12-15 00:00:00