Critical prevalence of antibodies minimizing vaccination costs for hepatitis A, hepatitis B, varicella, measles and tetanus in adults and adolescents in Catalonia, Spain.

abstract：:Pregnant goats were employed to assess unmarked deletion mutant vaccine candidates BMDeltaasp24, BMDeltacydBA, and BMDeltavirB2, as the target host species naturally infected with Brucella melitensis. Goats were assessed for the degree of pathology associated with the vaccine strains as well as the protective immunity...

journal_title：Vaccine

authors： Kahl-McDonagh MM,Elzer PH,Hagius SD,Walker JV,Perry QL,Seabury CM,den Hartigh AB,Tsolis RM,Adams LG,Davis DS,Ficht TA

更新日期：2006-06-12 00:00:00

abstract：INTRODUCTION:Adolescents and young adults are at a high risk of developing human papillomavirus (HPV) infections, which can be prevented with the use of vaccines. Moreover, a combined immunization strategy for administration of HPV vaccines with other routine vaccines may lead to better compliance. We aim to comprehens...

journal_title：Vaccine

authors： Li Y,Zhu P,Wu M,Zhang Y,Li L

更新日期：2020-01-10 00:00:00

abstract：:The potential outcomes of a Phase II schistosomiasis vaccine trial are explored using mathematical models which assume some natural immunity and a vaccine providing partial protection for a limited time. Analyses suggest that vaccination may have only a limited impact on life-long cumulative worm burdens and may lead ...

journal_title：Vaccine

authors： Woolhouse ME

更新日期：1995-08-01 00:00:00

abstract：:Carcinoembryonic antigen (CEA), which is expressed in several cancer types, is a potential target for specific immunotherapy. In this study, the feasibility of using dendrite cells (DCs) for tumor immunotherapy after transduction with a recombinant adenovirus containing CEA gene (AdVCEA) was investigated. The recombin...

journal_title：Vaccine

authors： Cho HI,Kim HJ,Oh ST,Kim TG

更新日期：2003-12-12 00:00:00

abstract：BACKGROUND:Tuberculosis is a major challenge for health care, as options for its treatment and prevention are limited. Therefore, novel approaches, such as DNA vaccination, to both prevent primary infections and the reactivation of latent infections need to be developed. A Mycobacterium marinum infection in adult zebra...

journal_title：Vaccine

authors： Niskanen M,Myllymäki H,Rämet M

更新日期：2020-07-31 00:00:00

abstract：:The prospective studies available today confirm the experience gained from several retrospective studies that TBE is a disease with a severe acute clinical course and considerable long-term morbidity. A defined post-encephalitic TBE syndrome exists, causing long-lasting morbidity that often affects the quality of life...

journal_title：Vaccine

authors： Haglund M,Günther G

更新日期：2003-04-01 00:00:00

abstract：:Taking the results of a prospective cohort study by our group that evaluated the effectiveness of the inactivated subunit virosomal influenza vaccine (Inflexal V), Crucell-Berna) in the prevention of influenza-related diseases and the reduction of its negative economic consequences, the economic costs and benefits for...

journal_title：Vaccine

authors： Salleras L,Navas E,Domínguez A,Ibáñez D,Prat A,Garrido P,Asenjo MA,Torner N

更新日期：2009-05-26 00:00:00

abstract：BACKGROUND:By the time clinical symptoms of Alzheimer's disease (AD) manifest in patients there is already substantial tau pathology in the brain. Recent evidence also suggests that tau pathology can become self-propagating, further accelerating disease progression. Over the last decade several groups have tested the e...

journal_title：Vaccine

authors： Davtyan H,Chen WW,Zagorski K,Davis J,Petrushina I,Kazarian K,Cribbs DH,Agadjanyan MG,Blurton-Jones M,Ghochikyan A

更新日期：2017-04-11 00:00:00

abstract：:Recombinant antigens from the oncosphere stage of the parasite Taenia solium were expressed in Escherichia coli. The TSOL16, TSOL45-1A and TSOL45-1B recombinant antigens, each consisting of fibronectin type III (FnIII) domain S, were produced as fusion proteins with glutathione S-transferase (GST) and maltose binding ...

journal_title：Vaccine

authors： Gauci CG,Jayashi CM,Gonzalez AE,Lackenby J,Lightowlers MW

更新日期：2012-06-06 00:00:00

abstract：:Widespread use of Pneumococcal Conjugate Vaccines (PCV) has reduced vaccine-type nasopharyngeal colonisation and invasive pneumococcal disease. In a double-blind, randomised controlled trial using the Experimental Human Pneumococcal Challenge (EHPC) model, PCV-13 (Prevenar-13) conferred 78% protection against colonisa...

journal_title：Vaccine

authors： German EL,Solórzano C,Sunny S,Dunne F,Gritzfeld JF,Mitsi E,Nikolaou E,Hyder-Wright AD,Collins AM,Gordon SB,Ferreira DM

更新日期：2019-07-09 00:00:00

abstract：:The ability of a genetically detoxified mutant of heat labile enterotoxin (LTK63) to act as a mucosal adjuvant following intranasal immunization with recombinant gD2 has previously been reported in mice [Ugozzoli M, O'Hagan DT, Ott GS. Intranasal immunization of mice with herpes simplex virus type 2 recombinant gD2: t...

journal_title：Vaccine

authors： O'Hagan D,Goldbeck C,Ugozzoli M,Ott G,Burke RL

更新日期：1999-05-04 00:00:00

abstract：:A gene encoding the mature Escherichia coli heat-labile enterotoxin B subunit (LTB) was introduced in a vector pNU212 and expressed at high levels in Bacillus brevis HPD31. The maximum amount of recombinant LTB (rLTB) secreted into the modified 5PY medium containing erythromycin was about 350 mg l(-1) when cultivated ...

journal_title：Vaccine

authors： Kozuka S,Yasuda Y,Isaka M,Masaki N,Taniguchi T,Matano K,Moriyama A,Ohkuma K,Goto N,Udaka S,Tochikubo K

更新日期：2000-03-06 00:00:00

abstract：BACKGROUND:A randomized trial demonstrated that a high-dose inactivated influenza vaccine (IIV-HD) was 24.2% more efficacious than a standard-dose vaccine (IIV-SD) against laboratory-confirmed influenza illness in adults ≥65 years. To evaluate the consistency of IIV-HD benefits, supplemental analyses explored efficacy ...

journal_title：Vaccine

authors： DiazGranados CA,Dunning AJ,Robertson CA,Talbot HK,Landolfi V,Greenberg DP

更新日期：2015-08-26 00:00:00

abstract：UNLABELLED:The Internet contains a large amount of useful information on many subjects, but also information of doubtful quality. To help identify Web sites on vaccine safety that fulfil good practice, the Global Advisory Committee on Vaccine Safety of the World Health Organization (WHO) has published criteria to which...

journal_title：Vaccine

authors： Martínez-Mora M,Alvarez-Pasquín MJ,Rodríguez-Salvanés F

更新日期：2008-12-09 00:00:00

abstract：BACKGROUND:The compliance with influenza vaccination among health-care workers (HCWs) is known to be low. A multi-nationality survey to explore the reasons for such poor compliance has not been studied in depth. MATERIALS AND METHODS:An epidemiologic survey to evaluate the compliance rates with influenza vaccination a...

journal_title：Vaccine

authors： Al-Tawfiq JA,Antony A,Abed MS

更新日期：2009-09-04 00:00:00

abstract：:This study compared responses of bison calves to 10(10)CFU of Brucella abortus strain RB51 (SRB51) delivered by parenteral or ballistic methods. Two types of biobullet payloads were evaluated; compacted SRB51 pellets or SRB51 encapsulated in photopolymerized poly(ethylene glycol) hydrogels. Bison were vaccinated with ...

journal_title：Vaccine

authors： Olsen SC,Christie RJ,Grainger DW,Stoffregen WS

更新日期：2006-02-27 00:00:00

abstract：:This paper presents the results of a global survey that aimed to collect information on country's immunization policy development processes, particularly on the presence and function of national Immunization Technical Advisory Groups (ITAGs). Characteristics of national ITAGs are described as well as attributes of the...

journal_title：Vaccine

authors： Bryson M,Duclos P,Jolly A,Cakmak N

更新日期：2010-04-19 00:00:00

abstract：:After 16 years of no vaccination against pertussis in Sweden, mass vaccination of infants and catch-up vaccination of children up to 10 years with a monocomponent pertussis toxoid vaccine was performed in the Greater Gothenburg area of Sweden between 1995 and 1999. At the end of the project in February 1999, 56% of al...

journal_title：Vaccine

authors： Trollfors B,Dotevall L,Sundh V,Welinder-Olsson C

更新日期：2011-03-16 00:00:00

abstract：:We successfully re-vaccinated hepatitis B virus (HBV) vaccine non-responders using a double dose of the combined hepatitis A virus (HAV) and HBV vaccine. The hope was to improve priming of hepatitis B surface antigen (HBsAg)-specific cell mediated immune response (CMI) by an increased antigen dose and a theoretical ad...

journal_title：Vaccine

authors： Nyström J,Cardell K,Björnsdottir TB,Fryden A,Hultgren C,Sällberg M

更新日期：2008-11-05 00:00:00

abstract：:Immunogenicity of inactivated virus or subviral vaccines may be enhanced by complexing with an IgG antibody. Such antibody would increase the uptake, processing and presentation of the vaccine's antigens by antigen presenting cells (APC), via the adhesion of the antibody-vaccine complex to Fc-receptors on macrophages ...

journal_title：Vaccine

authors： Galili U,Repik PM,Anaraki F,Mozdzanowska K,Washko G,Gerhard W

更新日期：1996-03-01 00:00:00

abstract：:Pneumococcal conjugate vaccines (PCV) may reduce nasopharyngeal carriage (NPC) of Streptococcus pneumoniae vaccine strains (VT), but serotype replacement with non-vaccine strains (NVT) has been reported. Bacterial NPC after PHiD-CV vaccination was assessed in the second year of life. Open descriptive study of NPC repo...

journal_title：Vaccine

authors： Prymula R,Hanovcova I,Splino M,Kriz P,Motlova J,Lebedova V,Lommel P,Kaliskova E,Pascal T,Borys D,Schuerman L

更新日期：2011-02-24 00:00:00

abstract：:We have found out that transfection of the RTG-2 cell line with the viral haemorrhagic septicaemia virus (VHSV) glycoprotein G (G(VHSV))-coding plasmid induces an anti-VHSV state, similar to that induced by poly I:C. Taking the advantage of the constitutive expression of toll-like receptor 9 gene (tlr9) in RTG-2 cells...

journal_title：Vaccine

authors： Ortega-Villaizan M,Chico V,Martinez-Lopez A,Falco A,Perez L,Coll JM,Estepa A

更新日期：2011-01-17 00:00:00

abstract：:A soluble fraction obtained from Bordetella pertussis was evaluated as adjuvant for the pertussis component of the Diphtheria-Pertussis-Tetanus (DPT) vaccine. High levels of antibodies were induced, and a 78% protection rate of mice challenged with live B. pertussis was observed. Two proteins were identified as the 73...

journal_title：Vaccine

authors： Cainelli Gebara VC,Risoléo L,Lopes AP,Ferreira VR,Quintilio W,Lépine F,Silva WD,Raw I

更新日期：2007-01-08 00:00:00

abstract：:Obesity is a risk factor for complicated influenza A/H1N1 disease and poor vaccine immunogenicity. Leptin, an adipocyte-derived hormone/cytokine, has many immune regulatory functions and therefore could explain susceptibility to infections and poor vaccine outcomes. We recruited 159 healthy adults (50-74 years old) wh...

journal_title：Vaccine

authors： Ovsyannikova IG,White SJ,Larrabee BR,Grill DE,Jacobson RM,Poland GA

更新日期：2014-02-07 00:00:00

abstract：INTRODUCTION:We performed a pooled analysis of randomised clinical trials (RCT) on HPV vaccine efficacy in preventing cervical persistent infection. METHODS:We carried out a bibliographic search on electronic databases and we selected RCT to perform the meta-analyses. RESULTS:We selected five studies. The first meta-...

journal_title：Vaccine

authors： La Torre G,de Waure C,Chiaradia G,Mannocci A,Ricciardi W

更新日期：2007-12-05 00:00:00

abstract：:Measles transmission has been well documented in healthcare facilities. Healthcare personnel who are unvaccinated and who lack other evidence of measles immunity put themselves and their patients at risk for measles. We conducted a systematic literature review of measles vaccination policies and their implementation i...

journal_title：Vaccine

authors： Fiebelkorn AP,Seward JF,Orenstein WA

更新日期：2014-08-27 00:00:00

abstract：:A recombinant vector vaccine uses an attenuated virus, bacterium, or parasite as the carrier to express a heterologous antigen(s). Many recombinant vaccine vectors and related vaccines have been developed and extensively investigated. To compare and better understand recombinant vectors and vaccines, we have generated...

journal_title：Vaccine

authors： Deng S,Martin C,Patil R,Zhu F,Zhao B,Xiang Z,He Y

更新日期：2015-11-27 00:00:00

abstract：:Development of active targeted immunotherapeutics is a rapid developing field in the arena of chronic infectious diseases. The question of repeated, closely spaced administration of immunotherapeutics to achieve a rapid impact on the replicating agent is an important one. We analyzed here, using a prototype adenovirus...

journal_title：Vaccine

authors： Boukhebza H,Dubois C,Koerper V,Evlachev A,Schlesinger Y,Menguy T,Silvestre N,Riedl P,Inchauspé G,Martin P

更新日期：2014-05-30 00:00:00

abstract：:A phase I clinical trial was performed to examine the safety and immunogenicity of a multi-epitope polypeptide comprising the central 15 amino acids of the V3 loop from six HIV-1 isolates. This protein called TAB9 was emulsified in Montanide ISA720 (Seppic, Paris) and administered intramuscularly at doses of 0, 0.2 an...

journal_title：Vaccine

authors： Toledo H,Baly A,Castro O,Resik S,Laferté J,Rolo F,Navea L,Lobaina L,Cruz O,Míguez J,Serrano T,Sierra B,Pérez L,Ricardo ME,Dubed M,Lubián AL,Blanco M,Millán JC,Ortega A,Iglesias E,Pentón E,Martín Z,Pérez J,Dí

更新日期：2001-07-20 00:00:00

abstract：BACKGROUND:Reactions to DTwP vaccine are well known and are a matter of great concern, much for the development of next generation combination vaccines. To avoid such reactions which occur from foreign compounds, WHO suggested manufacture of DTwP vaccine using semi-synthetic medium. The phase III trial reported here wa...

journal_title：Vaccine

authors： Sharma H,Patil V,Sharma D,Kapre S,Jadhav S,Ravetkar S,Kumar R,Bahl S,Parekh S,Chakravarty A

更新日期：2012-09-21 00:00:00