Improved cell mediated immune responses after successful re-vaccination of non-responders to the hepatitis B virus surface antigen (HBsAg) vaccine using the combined hepatitis A and B vaccine.

abstract：:Endospores of the Gram-positive bacterium, Bacillus subtilis, have been used successfully for delivery of antigens where the immunogen is expressed on the spore surface. In this work the spore has been engineered to deliver antigens to the cytoplasm of macrophages by expressing listeriolysin O (LLO) or a derivative, L...

journal_title：Vaccine

authors： Huang JM,La Ragione RM,Cooley WA,Todryk S,Cutting SM

更新日期：2008-11-11 00:00:00

abstract：:A DNA vaccine codifying the mycobacterial hsp65 can prevent infection with Mycobacterium tuberculosis in a prophylactic setting and also therapeutically reduce the number of bacteria in infected mice. The protective mechanism is thought to be related to Th1-mediated events that result in bacterial killing. To determin...

journal_title：Vaccine

authors： Lima KM,dos Santos SA,Santos RR,Brandão IT,Rodrigues JM Jr,Silva CL

更新日期：2003-12-08 00:00:00

abstract：:Immunization with xenogeneic DNA is a promising cancer treatment to overcome tolerance to self-antigens. Heat shock protein 70 (HSP70) is over-expressed in various kinds of tumors and is believed to be involved in tumor progression. This study tested a xenogeneic chicken HSP70 (chHSP70) DNA vaccine in an experimental ...

journal_title：Vaccine

authors： Yu WY,Chuang TF,Guichard C,El-Garch H,Tierny D,Laio AT,Lin CS,Chiou KH,Tsai CL,Liu CH,Li WC,Fischer L,Chu RM

更新日期：2011-04-18 00:00:00

abstract：BACKGROUND:Females who receive the human papillomavirus (HPV) vaccine may believe they are protected from developing cervical cancer and no longer require screening. Concern has also been expressed that vaccinated females are those that would be screened regularly. This study assesses the Pap testing behavior of vaccin...

journal_title：Vaccine

authors： Kliewer EV,Mahmud SM,Demers AA,Lambert P

更新日期：2013-12-17 00:00:00

abstract：BACKGROUND:The Polio Endgame strategy includes phased withdrawal of oral poliovirus vaccines (OPV) coordinated with introduction of inactivated poliovirus vaccine (IPV) to ensure population immunity. The impact of IPV introduction into a primary OPV series of immunizations in a developing country is uncertain. METHODS...

journal_title：Vaccine

authors： Mychaleckyj JC,Haque R,Carmolli M,Zhang D,Colgate ER,Nayak U,Taniuchi M,Dickson D,Weldon WC,Oberste MS,Zaman K,Houpt ER,Alam M,Kirkpatrick BD,Petri WA Jr

更新日期：2016-01-12 00:00:00

abstract：:The vast majority of women infected with human immunodeficiency virus (HIV) will be co-infected with human papillomavirus (HPV). The interaction between the two sexually transmitted infections appears to be related to the alteration in cell-mediated immunity in HIV infected persons, increased susceptibility, and possi...

journal_title：Vaccine

authors： Denny LA,Franceschi S,de Sanjosé S,Heard I,Moscicki AB,Palefsky J

更新日期：2012-11-20 00:00:00

abstract：:A gene associated with lipopolysaccharide (LPS) transport was cloned from a local clinical Vibrio cholerae O1 strain of the Ogawa serotype by using the Lactococcus lactis nisin-controlled expression (NICE) system. The V. cholerae wzm gene, which codes for an integral membrane transporter protein, was expressed and tar...

journal_title：Vaccine

authors： Zamri HF,Shamsudin MN,Rahim RA,Neela V

更新日期：2012-05-02 00:00:00

abstract：:The efficacy of chicken egg yolk homotypic antibodies specific for outer membrane proteins (OMP), lipopolysaccharide (LPS) or flagella (Fla) in controlling experimental salmonellosis in mice was investigated. Mice challenged orally with 2 x 10(9) c.f.u. of Salmonella enteritidis or 2 x 10(7) c.f.u. of S. typhimurium w...

journal_title：Vaccine

authors： Yokoyama H,Umeda K,Peralta RC,Hashi T,Icatlo FC Jr,Kuroki M,Ikemori Y,Kodama Y

更新日期：1998-02-01 00:00:00

abstract：:Bacterial flagellin is known to induce potent immune response in vertebrate systems via the toll-like receptor (TLR) 5. As a result, flagellin has been studied extensively as a vaccine adjuvant. In a previous study, we examined the vaccine and adjuvant potentials of the flagellin (FliC) of the fish pathogen Edwardsiel...

journal_title：Vaccine

authors： Jiao XD,Hu YH,Sun L

更新日期：2010-08-02 00:00:00

abstract：:Nine pigs were given a single inoculum of 100 microg of the all-D retro peptide corresponding to the immunodominant GH loop encompassing residues 141-159 of capsid protein VP1 of foot-and-mouth disease virus serotype A, sub-type 12. The peptide was conjugated to activated keyhole limpet haemocyanin and oil-adjuvanted ...

journal_title：Vaccine

authors： Nargi F,Kramer E,Mezencio J,Zamparo J,Whetstone C,Van Regenmortel MH,Briand JP,Muller S,Brown F

更新日期：1999-07-16 00:00:00

abstract：:Mutations arising in neutralizing epitopes of hepatitis C virus may play a role in the ability of the virus to escape control by neutralizing antibodies and in the establishment of chronic infections. An amino-acid substitution, Q412H, within a major conserved neutralization epitope EP I (aa 412-426) in the E2 glycopr...

journal_title：Vaccine

authors： Duan H,Struble E,Zhong L,Mihalik K,Major M,Zhang P,Feinstone S,Feigelstock D

更新日期：2010-06-07 00:00:00

abstract：:We compared the protection afforded by three different DNA application methods against bovine respiratory syncytial virus (BRSV) infection in cattle. A synthetic gene that codes for the G protein of BRSV was inserted into a eukaryotic vector and was used in the vaccine. Intradermal (i.d.) application with a needleless...

journal_title：Vaccine

authors： Schrijver RS,Langedijk JP,Keil GM,Middel WG,Maris-Veldhuis M,Van Oirschot JT,Rijsewijk FA

更新日期：1998-01-01 00:00:00

abstract：:Nearly half of the proteins in the complement system serve in regulation. Control at the central step of C3 activation is provided by an orchestrated interplay of membrane and plasma regulators. A model system employing Chinese hamster ovary (CHO) cells transfected with human regulators was employed to assist in makin...

journal_title：Vaccine

authors： Liszewski MK,Fang CJ,Atkinson JP

更新日期：2008-12-30 00:00:00

abstract：:The correlation between the antigen content of inactivated Newcastle disease (ND) oil emulsion-vaccines and the serological response after immunisation was studied. The haemagglutinin-neuraminidase (HN) and fusion (F) proteins of Newcastle disease virus (NDV) were quantified in 33 inactivated oil-adjuvanted ND vaccine...

journal_title：Vaccine

authors： Maas RA,Komen M,van Diepen M,Oei HL,Claassen IJ

更新日期：2003-07-04 00:00:00

abstract：:In the present study the homologous and heterologous type and subtype specific cellular immune response induced by a wild type inactivated whole virus H5N1 Influenza (A/Vietnam/1203/2004) vaccine was evaluated. Two immunizations with the Vero cell derived H5N1 influenza vaccine on Day 0 and Day 21 induced significant ...

journal_title：Vaccine

authors： Crowe BA,Brühl P,Gerencer M,Schwendinger MG,Pilz A,Kistner O,Koelling-Schlebusch K,Aichinger G,Singer J,Zeitlinger M,Müller M,Ehrlich H,Barrett PN

更新日期：2010-12-16 00:00:00

abstract：BACKGROUND:After the H1N1 swine flu vaccination campaign an increased number of narcolepsy cases in children and adolescents was observed in Scandinavian and later in further European countries that correlated with the vaccination by an AS03-adjuvanted influenza vaccine (Pandemrix). Narcolepsy is a chronic sleep disord...

journal_title：Vaccine

authors： Masoudi S,Ploen D,Kunz K,Hildt E

更新日期：2014-05-23 00:00:00

abstract：BACKGROUND:British Columbia (BC) introduced a school-based HPV vaccine program in September 2008. As part of the HPV vaccine program evaluation, we determined the type-specific HPV prevalence in a population-based sample of women presenting for routine cervical cancer screening in the province. METHODS:From June 2010 ...

journal_title：Vaccine

authors： Ogilvie GS,Cook DA,Taylor DL,Rank C,Kan L,Yu A,Mei W,van Niekerk DJ,Coldman AJ,Krajden M

更新日期：2013-02-04 00:00:00

abstract：:The effects of beta-propiolactone (BPL), an alkylating and virus inactivating agent, on the structural and in vitro biological properties of different DNA preparations from BHK-21 cells were investigated. Both uninfected and rabies virus-infected cells were used. Purified cellular DNA (celDNA) was used as the referenc...

journal_title：Vaccine

authors： Morgeaux S,Tordo N,Gontier C,Perrin P

更新日期：1993-01-01 00:00:00

abstract：:In accordance with the end game strategies for polio eradication a synchronized switch plan from tOPV to bOPV was implemented globally in 2016. The National Committee for Polio Eradication (NCCPE) validated the switch activities in India. An expert group of 104 academics conducted field visits in 25 states and 2 Union...

journal_title：Vaccine

authors： Dasgupta R,Sharma S,Sharma N,Banerjee K,Haran EGP,Muliyel JP,Salunke S,Masoodi MA,Haldar P,Bahl S,Bhatnagar P,Joshi S,Arora NK

更新日期：2019-04-17 00:00:00

abstract：:To assess the reactogenicity and immunogenicity of the Biken acellular pertussis vaccine (Pa) following administration of a single vaccine dose to young adults with or without a history of prior pertussis immunization, 104 healthy, male and female adults without primary pertussis immunization were enrolled in Mainz (f...

journal_title：Vaccine

authors： Schmitt HJ,Mohnike K,Zepp F,Herden P,Hosbach P

更新日期：2000-10-15 00:00:00

abstract：:Intranasal (i.n.) immunization of BALB/c mice with chimeric murine rotavirus EDIM (epizootic diarrhea of infant mice) VP6 and attenuated E. coli heat-labile toxin (LT), LT(R192G), stimulated >99% protection against rotavirus shedding after EDIM challenge. Here, we evaluated other potential adjuvants with chimeric VP6 ...

journal_title：Vaccine

authors： Choi AH,McNeal MM,Flint JA,Basu M,Lycke NY,Clements JD,Bean JA,Davis HL,McCluskie MJ,VanCott JL,Ward RL

更新日期：2002-03-15 00:00:00

abstract：:Severe diarrhea caused by rotavirus is a health problem worldwide, including Thailand. The World Health Organization has recommended incorporating rotavirus vaccination into national immunization programs. This policy has been implemented in several countries, but not in Thailand where the mortality rate is not high. ...

journal_title：Vaccine

authors： Muangchana C,Riewpaiboon A,Jiamsiri S,Thamapornpilas P,Warinsatian P

更新日期：2012-04-16 00:00:00

abstract：:By the strategy "reverse vaccinology" a number of new antigens have been identified in Neisseria meningitidis, which are potential candidates for a highly needed broad-spectrum meningococcal vaccine. In the present study we examined the prevalence, sequence constancies and variations of the genes encoding three of the...

journal_title：Vaccine

authors： Jacobsson S,Thulin S,Mölling P,Unemo M,Comanducci M,Rappuoli R,Olcén P

更新日期：2006-03-15 00:00:00

abstract：:In many countries, foot and mouth disease (FMD) is controlled by vaccination and surveillance against non-capsid proteins (NCP); therefore vaccines are required not to induce antibodies against NCP. Vaccine purity is evaluated by repeated inoculation of naïve cattle, an expensive and time consuming protocol that raise...

journal_title：Vaccine

authors： Capozzo AV,Martínez MR,Schielen WJ

更新日期：2010-09-14 00:00:00

abstract：:Due to viral strains, influenza season, and consultations and admission rates varying from country to country, the continued economic evaluation of influenza vaccination for the elderly people aged 65 years and above is paramount, particularly in areas with dense population. Efficacy and cost-effective analysis of inf...

journal_title：Vaccine

authors： Wang ST,Lee LT,Chen LS,Chen TH

更新日期：2005-03-14 00:00:00

abstract：:A systematic review was performed to assess the safety and immunogenicity of the prepandemic H5N1 influenza vaccines licensed so far. A bibliographic search according to the COSI protocol was carried out and 8 of 235 potentially relevant publications were selected. Quality assessment was defined with both CASP and Jad...

journal_title：Vaccine

authors： Prieto-Lara E,Llanos-Méndez A

更新日期：2010-06-11 00:00:00

abstract：:Because of the serious economic and medical consequences of brucellosis, efforts are to prevent infection of domestic animals through vaccines. Many disadvantages are associated with the current Brucella melitensis Rev.1 vaccine prompting development of alternative vaccines and delivery. Escherichia coli (DH5α) was en...

journal_title：Vaccine

authors： Gupta VK,Radhakrishnan G,Harms J,Splitter G

更新日期：2012-06-08 00:00:00

abstract：:We reviewed studies of rotavirus in MEDLINE and the Chinese literature to get a preliminary estimate of the burden of rotavirus gastroenteritis in China and the epidemiology of the disease. Studies were selected if they were conducted for a period 1 year or more, had more than 100 patients enrolled, and used an accept...

journal_title：Vaccine

authors： Orenstein EW,Fang ZY,Xu J,Liu C,Shen K,Qian Y,Jiang B,Kilgore PE,Glass RI

更新日期：2007-01-05 00:00:00

abstract：:In case of an influenza pandemic, the world will be in a situation where potential vaccine supply will fall short by several billion doses from global needs. The World Health Organization (WHO) convened in Geneva on May 2-3, 2006 a consultation of all stakeholders in influenza vaccines and immunization to identify pra...

journal_title：Vaccine

authors： Kieny MP,Costa A,Hombach J,Carrasco P,Pervikov Y,Salisbury D,Greco M,Gust I,LaForce M,Franco-Paredes C,Santos JI,D'Hondt E,Rimmelzwaan G,Karron R,Fukuda K

更新日期：2006-09-29 00:00:00

abstract：:Salmonella is one of the key global causes of food and water borne enteric infections, responsible for significant morbidity and mortality worldwide especially in developing countries. Currently available vaccines against typhoid are moderately effective with several side effects and not efficacious against all Salmon...

journal_title：Vaccine

authors： Verma S,Sugadev R,Kumar A,Chandna S,Ganju L,Bansal A

更新日期：2018-06-27 00:00:00