Characterization of the BUD31 gene of Saccharomyces cerevisiae.

abstract：:OPA1 is a cause gene for autosomal dominant optic atrophy and possesses eight alternative splicing variants. Here, we identified two isoforms of OPA1 proteins in HeLa cells and examined their submitochondrial localization and complex formations. RT-PCR shows that HeLa cells mainly express isoforms 7 and 1 of OPA1. Sin...

journal_title：Biochemical and biophysical research communications

authors： Satoh M,Hamamoto T,Seo N,Kagawa Y,Endo H

更新日期：2003-01-10 00:00:00

abstract：:A direct radioimmunoassay of atrial natriuretic factor (ANF) has been developed. The method uses a synthetic 26 amino-acid fragment (8-33 ANF) of the native peptide. Antibodies have been prepared in rabbits immunized with the peptide coupled to thyroglobulin. The radiolabelled tracer prepared by iodination according t...

journal_title：Biochemical and biophysical research communications

authors： Gutkowska J,Thibault G,Januszewicz P,Cantin M,Genest J

更新日期：1984-07-31 00:00:00

abstract：:Using a novel method consisting of chromatin fractionation and allele-specific detection, chromatin packaging is compared between active X (Xa) and inactive X (Xi) chromosomes for five tumor cell clones that were derived from inter-subspecific F1 female mice. Separation of heterochromatic (H) and euchromatic (E) fract...

journal_title：Biochemical and biophysical research communications

authors： Endo Y,Watanabe T,Kuwabara K,Tsunashima K,Mishima Y,Arakawa M,Takagi N,Kominami R

更新日期：1998-03-06 00:00:00

abstract：:Little is known about an oncogenic signal transducer β-1,4-galactosyltransferase-V (β-1,4-GalT-V), in human colorectal cancer. Using quantitative RT-PCR, immunohistochemical staining and ELISA assays, we determined that β-1,4-GalT-V gene/protein expression is specifically increased in human colorectal cancer (CRC) tum...

journal_title：Biochemical and biophysical research communications

authors： Chatterjee SB,Hou J,Bandaru VVR,Pezhouh MK,Syed Rifat Mannan AA,Sharma R

更新日期：2019-01-08 00:00:00

abstract：:Beta-catenin has essential roles in morphogenesis and human cancer, both as a subunit of adhesive complexes in the cell membrane and as a transcriptional coactivator in the Wnt signaling pathway. In addition, beta-catenin also has the ability to transport lymphoid enhancer binding factor-1 into the nucleus. In this st...

journal_title：Biochemical and biophysical research communications

authors： Hsu HT,Liu PC,Ku SY,Jung KC,Hong YR,Kao C,Wang C

更新日期：2006-05-12 00:00:00

abstract：:The close association of inflammation, angiogenesis and cancer progression is now highlighted, and in this study we especially focused on a close association of inflammation and lymphangiogenesis. We found that proinflammatory cytokine, interleukin-1beta (IL-1beta), could induce lymphangiogenesis in mouse cornea throu...

journal_title：Biochemical and biophysical research communications

authors： Watari K,Nakao S,Fotovati A,Basaki Y,Hosoi F,Bereczky B,Higuchi R,Miyamoto T,Kuwano M,Ono M

更新日期：2008-12-19 00:00:00

abstract：:Quercetin is one of the most prominent dietary antioxidants. During its antioxidant activity, quercetin becomes oxidized into its o-quinone/quinone methide QQ. QQ is toxic since it instantaneously reacts with thiols of, e.g., proteins. In cells, QQ will initially form an adduct with glutathione (GSH), giving GSQ. We h...

journal_title：Biochemical and biophysical research communications

authors： Boots AW,Balk JM,Bast A,Haenen GR

更新日期：2005-12-16 00:00:00

abstract：:Evolutionary conserved SET domains were originally identified in three Drosophila proteins: suppressor of variegation (Su (var) 3-9), enhancer of zeste (E(z)), and the trithorax. Some of the SET-domain containing proteins have been known to elicit methylation of histone lysine residues. Based on a search for SET-domai...

journal_title：Biochemical and biophysical research communications

authors： Kim SM,Kee HJ,Eom GH,Choe NW,Kim JY,Kim YS,Kim SK,Kook H,Kook H,Seo SB

更新日期：2006-06-23 00:00:00

abstract：:Sensory transduction in the cochlea depends on regulated ion secretion and absorption. Results of whole-organ experiments suggested that Reissner's membrane may play a role in the control of luminal Cl(-). We tested for the presence of Cl(-) transport pathways in isolated mouse Reissner's membrane using whole-cell pat...

journal_title：Biochemical and biophysical research communications

authors： Kim KX,Marcus DC

更新日期：2010-04-02 00:00:00

abstract：:Previous studies showed that insulin stimulation of electrogenic Na+ transport in renal epithelial cells is mediated by a calcium-dependent signal transduction mechanism. The present study was performed to determine whether the insulin-induced increase in intracellular Ca2+ (Cai2+) was mediated by hydrolysis of phosph...

journal_title：Biochemical and biophysical research communications

authors： Isales C,Macala LJ,Rodriguez-Commes J,Gasalla-Herraiz J,Hayslett JP

更新日期：1997-02-03 00:00:00

abstract：:Whether mitochondrial Ca(2+) transport is rapid enough to respond to changes in cytosolic [Ca(2+)] ([Ca(2+)](c)) which occur during excitation-contraction coupling in the heart is controversial; different results wereobtained with different techniques and different species. In this study mitochondrial [Ca(2+)] ([Ca(2+...

journal_title：Biochemical and biophysical research communications

authors： Griffiths EJ

更新日期：1999-09-24 00:00:00

abstract：:A phosphoprotein with associated tyrosine kinase activity has been purified from a 26,000 x g particulate fraction of rat spleen. The molecular weight of the native kinase is 85-90 kDa as estimated by gel permeation chromatography on Superdex 200 while SDS/PAGE of an autophosphorylated sample indicated a single 28-kDa...

journal_title：Biochemical and biophysical research communications

authors： Borowski P,Medem S,Laufs R

更新日期：1993-07-30 00:00:00

abstract：:Plucked (pk) is an autosomal recessive mouse mutation with a hair phenotype that arose spontaneously in the DBA/2J strain. Histological studies indicate that adult pk mutant mice lose truncal hair because of the scarring of follicles due to an apparent obstruction of the outward movement of the hair shaft within the f...

journal_title：Biochemical and biophysical research communications

authors： Luo J,Zhang L,Stenn K,Prouty S,Parimoo S

更新日期：2005-02-04 00:00:00

abstract：:Because brain inositides are enriched in the 1-stearoyl-2-arachidonoyl species, they form a likely source for the tetraenoic free fatty acids (FFA) and diacylglycerols (DG) that are accumulated during seizures. To study inositide turnover during bicuculline-induced seizures, rats were injected intraventricularly and b...

journal_title：Biochemical and biophysical research communications

authors： Van Rooijen LA,Vadnal R,Dobard P,Bazan NG

更新日期：1986-04-29 00:00:00

abstract：:Trypanosoma cruzi, the etiological agent of Chagas' disease, is the only eukaryotic cell which lacks the ability to synthesize polyamines de novo. In this work, we describe for the first time the molecular and biochemical properties of a high-affinity spermidine transporter from T. cruzi. The transporter gene TcPAT12 ...

journal_title：Biochemical and biophysical research communications

authors： Carrillo C,Canepa GE,Algranati ID,Pereira CA

更新日期：2006-06-09 00:00:00

abstract：:Hepatocyte Growth Factor (HGF) was originally identified as hepatotrophic factor for liver regeneration. More recently, HGF was revealed to stimulate proliferation of various epithelial cells. At present study, we have investigated the mitogenic effect of HGF on gastric epithelial cells in the primary culture system. ...

journal_title：Biochemical and biophysical research communications

authors： Takahashi M,Ota S,Terano A,Yoshiura K,Matsumura M,Niwa Y,Kawabe T,Nakamura T,Omata M

更新日期：1993-03-15 00:00:00

abstract：:The Xenopus homologue of sonic hedgehog (Xhh) was detected in Xenopus embryos at stages 13 and 31 by RT-PCR, but it was not expressed in explants isolated from the animal hemisphere of Xenopus embryos at stage 8-9. Treatment of the animal cap with activin (1-100 ng/ml) induced the expression of Xhh. However, it was no...

journal_title：Biochemical and biophysical research communications

authors： Yokotal C,Mukasa T,Higashi M,Odaka A,Muroya K,Uchiyama H,Eto Y,Asashima M,Momoi T

更新日期：1995-02-06 00:00:00

abstract：:S-100 protein and annexin II2-p11(2) were reported to inhibit and to stimulate the assembly of glial fibrillary acidic protein (GFAP), respectively, in a Ca(2+)-dependent manner. Here we show by a number of experimental approaches that S-100 protein contrasts all the effects of annexin II2-p11(2) on GFAP assembly and,...

journal_title：Biochemical and biophysical research communications

authors： Bianchi R,Garbuglia M,Verzini M,Giambanco I,Spreca A,Donato R

更新日期：1995-03-28 00:00:00

abstract：:We examined the affinity of transthyretin (TTR) for lipoproteins and the effect of lipoproteins on TTR-related amyloidogenesis using serum samples from healthy volunteers and patients with familial amyloidotic polyneuropathy (FAP) ATTRVal30Met. In both volunteers and patients, TTR levels were highest in the VLDL fract...

journal_title：Biochemical and biophysical research communications

authors： Sun X,Ando Y,Haraoka K,Katsuragi S,Yamashita T,Yamashita S,Okajima M,Terazaki H,Okabe H

更新日期：2003-11-14 00:00:00

abstract：:We have identified two neuropeptides (F1 and F2) from suboesophageal and thoracic ganglia of Locusta migratoria, which we isolated earlier based on their immunological similarity to arginine vasopressin. The more abundant and hydrophilic factor, F1, has sequence Cys-Leu-Ile-Thr-Asn-Cys-Pro-Arg-Gly-NH2, but its biologi...

journal_title：Biochemical and biophysical research communications

authors： Proux JP,Miller CA,Li JP,Carney RL,Girardie A,Delaage M,Schooley DA

更新日期：1987-11-30 00:00:00

abstract：:Myostatin belongs to the transforming growth factor (TGF)-beta superfamily and is a potent negative regulator of skeletal muscle development and growth. We utilized microinjection of an antisense RNA-expressing vector to establish a hereditarily stable myostatin gene knockdown zebrafish strain with a double-muscle phe...

journal_title：Biochemical and biophysical research communications

authors： Lee CY,Hu SY,Gong HY,Chen MH,Lu JK,Wu JL

更新日期：2009-10-02 00:00:00

abstract：:Calyculin A (CL-A), a toxin isolated from the marine sponge Discodermia calyx, is a strong inhibitor of protein phosphatase 1 (PP1) and 2A (PP2A). Although CL-A is known to induce rapid neurite retraction in developing neurons, the cytoskeletal dynamics of this retraction have remained unclear. Here, we investigated t...

journal_title：Biochemical and biophysical research communications

authors： Inutsuka A,Goda M,Fujiyoshi Y

更新日期：2009-12-25 00:00:00

abstract：:Current studies were undertaken to determine the presence of a specific antigenic protein on the outer membrane of Salmonella typhi. Immunoblot analysis using sera from patients with fevers revealed that the 50 kD band was specifically recognized only by typhoid sera. The 50 kD band located on the outer membrane is pr...

journal_title：Biochemical and biophysical research communications

authors： Ismail A,Hai OK,Kader ZA

更新日期：1991-11-27 00:00:00

abstract：:A mathematical model that includes biochemical interactions among the PTS system, phosphofructokinase (PFK), and pyruvate kinase (PK) is used to evaluate the dynamic behavior of the glycolytic pathway of Escherichia coli under steady-state conditions. The influence of ADP, phosphoenolpyruvate (PEP), and fructose-6-pho...

journal_title：Biochemical and biophysical research communications

authors： Diaz Ricci JC

更新日期：2000-04-29 00:00:00

abstract：:In this study, we found that lincRNA-TINCR was significantly upregulated in burn-injured skin tissues in vivo and heat-stimulated dermal fibroblasts in vitro, accompanied by an increase in TGF-β1 expression. TINCR overexpression promoted cell proliferation, colony formation, release of pro-inflammatory factors and exp...

journal_title：Biochemical and biophysical research communications

authors： Qin G,Song Y,Guo Y,Sun Y,Zeng W

更新日期：2019-02-19 00:00:00

abstract：:Fut8 (α1,6-Fucosyltransferase) heterozygous knock-out (Fut8(+/-)) mice had an increased influx of inflammatory cells into the lungs, and this was associated with an up-regulation of matrix metalloproteinases, MMP-2 and MMP-9, after treatment with porcine pancreatic elastase (PPE), exhibiting an emphysema-prone phenoty...

journal_title：Biochemical and biophysical research communications

authors： Kamio K,Yoshida T,Gao C,Ishii T,Ota F,Motegi T,Kobayashi S,Fujinawa R,Ohtsubo K,Kitazume S,Angata T,Azuma A,Gemma A,Nishimura M,Betsuyaku T,Kida K,Taniguchi N

更新日期：2012-07-20 00:00:00

abstract：:Specifier proteins are important components of the glucosinolate-myrosinase system, which mediate plant defense against herbivory and pathogen attacks. Upon tissue disruption, glucosinolates are hydrolyzed to instable aglucones by myrosinases, and then aglucones will rearrange to form defensive isothiocyanates. Specif...

journal_title：Biochemical and biophysical research communications

authors： Zhang W,Wang W,Liu Z,Xie Y,Wang H,Mu Y,Huang Y,Feng Y

更新日期：2016-09-16 00:00:00

abstract：:The expansion of a CAG trinucleotide repeat (TNR) sequence has been linked to several neurological disorders, for example, Huntington's disease (HD). In HD, healthy individuals have 5-35 CAG repeats. Those with 36-39 repeats have the premutation allele, which is known to be prone to expansion. In the disease state, gr...

journal_title：Biochemical and biophysical research communications

authors： Jarem DA,Delaney S

更新日期：2011-12-09 00:00:00

abstract：:Microinjection of inositol 1,3,4,5-tetrakisphosphate or inositol 1,4,5-trisphosphate induced distinct chloride membrane currents in defolliculated Xenopus laevis oocytes. To decide whether these Cl(-)-currents were due to the injected compounds or their metabolic products, [3H]Ins(1,3,4,5)P4 or [3H]Ins(1,4,5)P3 were i...

journal_title：Biochemical and biophysical research communications

authors： Guse AH,Gercken G,Boysen H,Schwarz JR,Meyerhof W

更新日期：1991-08-30 00:00:00

abstract：:Liraglutide, a glucagon-like peptide 1 (GLP-1) analogue, could reverse NAFLD-induced liver damage by improving metabolic profiles, but the exact molecular mechanism has not been elucidated. Sestrin2 is a novel antioxidant protein, essential for regulating metabolic homeostasis. However, whether sestrin2-mediated redox...

journal_title：Biochemical and biophysical research communications

authors： Han X,Ding C,Zhang G,Pan R,Liu Y,Huang N,Hou N,Han F,Xu W,Sun X

更新日期：2020-05-14 00:00:00