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Cortical slow potential changes during convulsions induced by maximal electroshock or penicillin focus.

Abstract：

:We have described the occurrence in freely moving gerbils of slow potential changes (SPC) in two different models of experimental epilepsy: 1) maximal electroshock and 2) bilateral epileptic foci induced by penicillin. SPC is considered a by-product of epileptiform activity in both models and correlates to the SPC which occurs during spreading depression. In the first model there develops a cortical SPC simultaneous with a depression of EEG activity, although there is no propagation of the wave. We suggest that a non-propagated multifocal depression (MD) occurs in the MES model. In the model of focal epilepsy, all requirements are fulfilled, and the SPC is characterized as the one which occurs during spreading depression propagating with an average velocity of 8 mm/min.

journal_name

Metab Brain Dis

journal_title

Metabolic brain disease

authors

de Azeredo FA,Perret ML

doi

10.1007/BF01000149

subject

Has Abstract

pub_date

1992-06-01 00:00:00

pages

101-13

issue

2

eissn

0885-7490

issn

1573-7365

journal_volume

7

pub_type

杂志文章

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