Abstract：
INTRODUCTION:In recent years several authors have proposed that muscle pathological changes in humans with dystrophin disorders and in mdx-mice are the result of regeneration attempts of this tissue subjected to constantly repeated bouts of necrosis. AIM:We compared morphological aspects of degenerative-regenerative groups observed in the mdx-mice with the regenerative phases that follow an intramuscular injection of 30 mL glycerol. MATERIALS AND METHODS:Gastrocnemius samples from mdx-mice, 1 to 5 months old and from glycerol injected C57Bl10/ScSn mice, 4 to 8 months old, were processed and analyzed in parallel. RESULTS:We were able to recognize degenerative-regenerative group stages in the mdx-mice that closely matched the anomalies found 1, 2, 3, 4-5, 7 and 21-28 days following the injection with glycerol. CONCLUSION. This study reinforces the hypothesis that muscle pathologic abnormalities of mdx-mice are the result of chronic muscle necrosis-regeneration. Morphologic mdx-mice degenerative-regenerative group staging will be a helpful tool for future investigation of muscle regeneration.
journal_name
Rev Neuroljournal_title
Revista de neurologiaauthors
Roig-Quilis M,Roma J,Marotta M,Sarria Y,Fargas Asubject
Has Abstractpub_date
2004-06-16 00:00:00pages
1101-8issue
12eissn
0210-0010issn
1576-6578pii
rn2004144journal_volume
38pub_type
杂志文章abstract：OBJECTIVE:To determine clinical and pathological features with seizures associated brain tumors. PATIENTS AND METHODS:This was a retrospective study through of an Epilepsy Program Protocol where we studied fifty patients admitted at Hospital Universitário Cajuru of Curitiba, Brazil, in 1996-1997. RESULTS:We studied 3...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1999-06-01 00:00:00
abstract：OBJECTIVE:In this paper we review the main aetiologies of metabolic origin which cause epilepsy in children aged between 1 and 10 years. DEVELOPMENT:There are many aetiological causes of convulsive seizures. Seizures and epilepsies due to congenital errors of metabolism are a minority but should be known. Their identi...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2002-09-01 00:00:00
abstract：INTRODUCTION:There is now growing evidence that essential tremor and Parkinson's disease are related. AIM:To present the main findings from epidemiologic, genetic, clinical, imaging and pathologic studies, contrasting evidences for and against an association between essential tremor and Parkinson's disease. DEVELOPME...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2012-10-16 00:00:00
abstract：INTRODUCTION:Purely bulbar hematomas are not common (0.25%-0.50% of all intraparenchymatous hematomas), probably because of the particular characteristics of the anatomy and hemodynamics of the bulbar circulation. CLINICAL CASES:We selected 18 cases. Three of these were our own and the purely bulbar localization was c...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：1998-10-01 00:00:00
abstract：INTRODUCTION:Olivopontocerebellar atrophy (OPCA) is a degenerative disease of the nervous system (NS) which currently has no known cure. The neuronal depopulation it brings about produces a number of neurochemical alterations, including a reduction in levels of gamma-aminobutyric acid (GABA) in tissues and in cerebrosp...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2005-03-01 00:00:00
abstract：:The Minimental State Examination (MMSE), created in 1975 as a tool for briefly evaluating the patient's mental state, has been widely used and is the most frequently cited cognitive test on Medline, as well as being the one with the most versions in different languages (over 70). Through a review of the Medline databa...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2015-10-16 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2001-03-01 00:00:00
abstract：AIMS:To analyze the validity of the single deck 64-card Wisconsin Card Sorting Test (WCST-64) compared to the standard version (WCST-128), and to study the sensibility of both versions to identify changes over time in patients with traumatic brain injury (TBI). PATIENTS AND METHODS:The WCST was administered twice acro...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2008-02-01 00:00:00
abstract：INTRODUCTION:Aseptic meningitis is a process that is characterised by an inflammatory reaction of the meninges that is not due to any infectious agent. Its aetiology is varied and is most frequently caused by rheumatologic and/or autoimmune processes, chemical or medication-induced meningitis, the most notable drugs in...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2006-02-16 00:00:00
abstract：INTRODUCTION AND AIMS:Trepanation is one of the earliest examples of a surgical procedure being carried out by human beings and was performed from the Neolithic period onwards in a large number of primitive cultures throughout the five continents. Trepanation and cranial deformation were both common in the pre-Columbin...
journal_title：Revista de neurologia
pub_type： 历史文章,杂志文章
doi：
更新日期：2004-05-01 00:00:00
abstract：INTRODUCTION:There is increasing evidence that B cells and humoral immunity play key roles in the pathogenesis of multiple sclerosis (MS). Ocrelizumab, an anti-CD20 monoclonal antibody, has been shown to be effective in controlling the disease and has recently been aproved by the Food and Drug Administration for the tr...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2018-01-01 00:00:00
abstract：INTRODUCTION:Tumours in the pineal region are rare (0.3-2.7%) and most of the ones that do occur are germ cell tumours, of which germinoma is the most frequent. They are chiefly located in the pineal gland, the next most common being site being the suprasellar region and the fourth ventricle, although simultaneous pres...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2008-04-01 00:00:00
abstract：INTRODUCTION:In recent years Internet has drastically transformed the world of telecommunications. Questions about whether Internet and the global communication accessibility may be considered as a fundamental aspect in the medicine of today and tomorrow have been brought up. OBJECTIVE:Discuss current and future appli...
journal_title：Revista de neurologia
pub_type：
doi：
更新日期：1998-04-01 00:00:00
abstract：AIM:To estimate the prevalence of dementia in the population aged above 65 in the district of Mungialde, Vizcaya. SUBJECTS AND METHODS:We conducted a two-phase door-to-door populational study. The Minimental State Examination and the Pfeiffer questionnaire were used in the screening phase. The Clinical Dementia Rating...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2008-01-16 00:00:00
abstract：INTRODUCTION:Temporal orientation is a component of most screening tests for diagnosing cognitive impairment. Correct temporal orientation involves activating both semantic information (concepts of the calendar date) and episodic information (remembering the current date). AIMS:The aim of this study was to assess the ...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2011-03-16 00:00:00
abstract：INTRODUCTION:To study the role of the serotonin transporter gene (SLC6A4) in the emotional processing of auditory hallucinations can be particularly important to better understand the pathophysiology of auditory hallucinations. Moreover, a poly-morphism located in this gene (5-HTTLPR) has been previously associated wit...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2010-03-16 00:00:00
abstract：INTRODUCTION:Alzheimer's disease is 1.5 to 3 times more frequent in women than in men. This fact can be biased as women as a group have more long life survival. Semantic memory and naming are more frequently and severely impaired in women. DEVELOPMENT:Both genetic and environmental factors can contribute when one dete...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2001-06-16 00:00:00
abstract：:The evidence base from empirical studies is one of the elements, along with patients' preference and consideration of particular clinical state and circumstances, that should be taken into account in the process of clinical decision making. This paper provides an overview of the current evidence base for the treatment...
journal_title：Revista de neurologia
pub_type：
doi：
更新日期：2017-02-24 00:00:00
abstract：TITLE:GNAO1: un nuevo gen a considerar en la distonia temprana de la infancia. : ...
journal_title：Revista de neurologia
pub_type： 信件,评审
doi：
更新日期：2018-05-01 00:00:00
abstract：INTRODUCTION AND AIMS:Mercury is a metal that is widely used in hundreds of applications nowadays. This metal has proved to be extremely toxic in humans, especially for the central nervous system, both in cases of exposure from everyday applications (e.g. dental fillings) and from environmental exposure. Unfortunately,...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2005-04-01 00:00:00
abstract：INTRODUCTION:At present, cholinesterase inhibitors constitute the basis for therapy of Alzheimer's disease (AD); these drugs were rationally introduced given the loss of central cholinergic neurotransmission, even though there are many other systems affected in AD, including glutamatergic pathway. DEVELOPMENT:In addit...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2006-04-16 00:00:00
abstract：INTRODUCTION:Cystinosis is a hereditary disease with clinical symptoms that are caused by the accumulation of cystine crystals in different tissues. Distal vacuolar myopathy has been reported as one of its later complications. CASE REPORT:Here, we present the case of a 20-year-old male diagnosed with cystinosis at the...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2005-02-01 00:00:00
abstract：INTRODUCTION:Checkpoint inhibitors have dramatically transformed cancer treatment. However, due to the increasing number of tumors in which they are used, there is a high number of reported adverse effects. Among them, we highlight neurological side effects. In the approbatory clinical trials, they were thought to be s...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：10.33588/rn.6807.2019022
更新日期：2019-04-01 00:00:00
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journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2007-07-01 00:00:00
abstract：:INTRODUCTION. Dystrophinopathies are X-linked genetic disorders caused by mutations in the DMD gene. Genetic tests are of utmost importance for management and genetic counseling of these diseases. However, the complexity of the DMD gene is a challenge for diagnosis. AIM. To describe recent advances in the diagnosis of...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2011-02-16 00:00:00
abstract：:The neuropathology of haemorrhagic and hypoxic-ischaemic perinatal encephalopathies and their effect on the post-natal development of the brain, has been studied in children who survived with these lesions (for days, weeks, months and even years). Eventually some children developed neurological sequelae, including epi...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1997-05-01 00:00:00
abstract：INTRODUCTION:Semi-structured questionnaires, based on clinical criteria are used in the diagnosis of headache, but none has been used to study the two commonest types of chronic headache. The first step, before clinical application, is to carry out a study of the questionnaire's validity and predictive value. OBJECTIV...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：1998-03-01 00:00:00
abstract：INTRODUCTION:Cochrane Collaboration (CC) contains detailed, critical and up-to-date systematic reviews (SR) of the best scientific evidence available. AIM:To analyse the bibliometric characteristics of the SR related to paediatric neurology published in the 50 Collaborative Review Groups (CRG) of the CC. MATERIALS AN...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2006-11-16 00:00:00
abstract：INTRODUCTION AND METHOD:Dementia with Lewy bodies is a generative brain disease of unknown origin, characterised clinically by progressive mental deterioration, with striking fluctuations and transitory episodes of confusion, hallucinations and psychotic symptoms (hallucinations and paranoid deliria), extrapyramidal si...
journal_title：Revista de neurologia
pub_type： 杂志文章,评审
doi：
更新日期：2002-10-16 00:00:00
abstract：INTRODUCTION:Immigration is shaping a new model of society, with new needs and demands, whose characteristics must guide health-care policies. AIM. To determine the repercussions of the phenomenon of immigration on the extra-hospital neurological care carried out in Department 16 of the Agencia Valenciana de Salud (Val...
journal_title：Revista de neurologia
pub_type： 杂志文章
doi：
更新日期：2009-08-16 00:00:00
