Abstract:
:Measures of visual contrast sensitivity (VCS), rather than traditional measures of visual acuity using high-contrast stimuli, have been presented as better appraisals of visual dysfunction resulting from chemical exposures. The present study sought to determine if differences exist between two available measures of contrast sensitivity that use similar stimuli, specifically, a hand-held chart and an Optec 1000 vision tester. Monocular contrast sensitivity measures using both tests were obtained from 45 individuals as part of a NIOSH neurobehavioral test-battery appraisal. Test-retest reliability was found to be high for both the hand-held system and the Optec 1000 test (r=.750 and.773, respectively). In comparison to the automated test, the hand-held version produced statistically significant higher contrast sensitivity scores for lower spatial frequencies (1.5 and 3.0 cycles per degree) and lower scores for a relatively higher spatial frequency (18.0 cycles per degree [cpd]). Consequently, this study documents a difference in spatial frequency scores obtained with the hand-held form and Optec 1000 form of contrast sensitivity test, and attributes these differences to design characteristics affecting viewing. It is concluded that caution should be taken when making absolute comparisons of contrast sensitivity test scores between neurobehavioral studies that have used different forms of VCS testing.
journal_name
Neurotoxicol Teratoljournal_title
Neurotoxicology and teratologyauthors
Hitchcock EM,Dick RB,Krieg EFdoi
10.1016/j.ntt.2003.10.007subject
Has Abstractpub_date
2004-03-01 00:00:00pages
271-7issue
2eissn
0892-0362issn
1872-9738pii
S0892036203001430journal_volume
26pub_type
杂志文章abstract::A multidisciplinary study to investigate 2,5-hexanedione (2,5-HD)-induced CNS-neurotoxicity and its proposed potentiation by acetone (AC) was conducted. Neurobehavioral testing, estimation of the brain-swelling reaction, neuropathological and morphometric measurements as well as synaptosomal 5-hydroxytryptamine (5-HT)...
journal_title:Neurotoxicology and teratology
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journal_title:Neurotoxicology and teratology
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journal_title:Neurotoxicology and teratology
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journal_title:Neurotoxicology and teratology
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doi:10.1016/j.ntt.2006.08.007
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journal_title:Neurotoxicology and teratology
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journal_title:Neurotoxicology and teratology
pub_type: 杂志文章
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pub_type: 杂志文章
doi:10.1016/0892-0362(94)00076-p
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journal_title:Neurotoxicology and teratology
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doi:10.1016/j.ntt.2018.01.007
更新日期:2018-01-01 00:00:00
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journal_title:Neurotoxicology and teratology
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doi:10.1016/j.ntt.2010.05.001
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journal_title:Neurotoxicology and teratology
pub_type: 杂志文章,评审
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pub_type: 杂志文章
doi:10.1016/0892-0362(91)90026-s
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journal_title:Neurotoxicology and teratology
pub_type: 杂志文章
doi:10.1016/j.ntt.2006.10.009
更新日期:2007-03-01 00:00:00
abstract::We examined the relationship between acquired color vision loss and exposure to toluene and total hydrocarbons among 125 male workers. Seventy-two toluene-exposed printers were compared with 34 workers from the same photogravure plant with ambient background exposure, and with 19 workers from a bookbinding plant locat...
journal_title:Neurotoxicology and teratology
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doi:10.1016/s0892-0362(01)00163-5
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journal_title:Neurotoxicology and teratology
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abstract:OBJECTIVE:The present study examined the impact of both perinatal maternal depression and cocaine use on infant neurobehavior at 1 month of age in a large, multi-site study. METHODS:Infant neurobehavior was examined in 1053 infants at 1 month of age using the NICU Network Neurobehavioral Scale (NNNS). Mothers were int...
journal_title:Neurotoxicology and teratology
pub_type: 杂志文章,多中心研究
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journal_title:Neurotoxicology and teratology
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journal_title:Neurotoxicology and teratology
pub_type: 临床试验,杂志文章
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journal_title:Neurotoxicology and teratology
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doi:10.1016/s0892-0362(97)00039-1
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journal_title:Neurotoxicology and teratology
pub_type: 杂志文章
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journal_title:Neurotoxicology and teratology
pub_type: 杂志文章
doi:10.1016/0892-0362(90)90015-5
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journal_title:Neurotoxicology and teratology
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abstract::Researchers in the Netherlands have reported that the associations of prenatal polychlorinated biphenyl (PCB) exposure with poorer cognitive performance in childhood are generally stronger and statistically significant only among non-breast-fed children. This paper reports a similar pattern of greater vulnerability am...
journal_title:Neurotoxicology and teratology
pub_type: 杂志文章
doi:10.1016/s0892-0362(02)00197-6
更新日期:2002-05-01 00:00:00
abstract::Understanding the potentially harmful long term consequences of prenatal marijuana exposure is important given the increase in number of pregnant women smoking marijuana to relieve morning sickness. Altered executive functioning is one area of research that has suggested negative consequences of prenatal marijuana exp...
journal_title:Neurotoxicology and teratology
pub_type: 杂志文章,评审
doi:10.1016/j.ntt.2016.05.010
更新日期:2016-01-01 00:00:00
abstract::Maternal smoking during pregnancy greatly enhances perinatal morbidity/mortality and is the major risk factor for Sudden Infant Death Syndrome (SIDS). Studies in developing rodents indicate that nicotine is a neuroteratogen that targets monoamine pathways involved in the responses to hypoxia that are in turn, hypothes...
journal_title:Neurotoxicology and teratology
pub_type: 杂志文章
doi:10.1016/j.ntt.2011.02.001
更新日期:2011-05-01 00:00:00