Abstract：
:The gut tissues and associated nervous system of the African migratory locust, Locusta migratoria, were found to contain FMRFamide-like immunoreactive (FLI) material throughout the five larval instars and 2 weeks into the adult stage in both males and females. FMRFamide-like immunoreactivity associated with the locust gut was described using camera lucida techniques. FMRFamide-like immunoreactivity is observed in the frontal connectives, recurrent nerve, and oesophageal nerves; projections from the ingluvial ganglion onto the anterior midgut, and from the proctodeal nerve onto the hindgut and posterior midgut; in the neuropils of the frontal ganglion, hypocerebral ganglion and ingluvial ganglia; 30 cell bodies in the frontal ganglion; multipolar sensory cells on the foregut; and endocrine-like cells in the gastric caecae and midgut. Radioimmunoassay (RIA) was used to determine the quantities of FLI material in foreguts, gastric caecae, anterior and posterior midguts, and hindgut of first-fifth instar larvae, 1-3- and 14-17-day male and female adult locusts. As expected, as the tissue size (assessed by total protein content) increases, so does the amount of FLI material in each tissue. Normalizing for tissue size reveals significant differences in FLI content among the stages for each tissue tested. Reversed phase-high pressure liquid chromatography (RP-HPLC) followed by RIA has identified four groups of FLI fractions present in the gut, and different members of these groups are present in the various gut tissues.
journal_name
Peptidesjournal_title
Peptidesauthors
Hill SR,Orchard Idoi
10.1016/j.peptides.2003.08.013subject
Has Abstractpub_date
2003-10-01 00:00:00pages
1511-24issue
10eissn
0196-9781issn
1873-5169pii
S019697810300322Xjournal_volume
24pub_type
杂志文章相关文献
PEPTIDES文献大全abstract：:Alzheimer's disease is one of the most common dementia among elderly worldwide. There is no therapeutic drugs until now to treat effectively this disease. One main reason is due to the poorly understood mechanism of Aβ peptide aggregation, which plays a crucial role in the development of Alzheimer's disease. It remain...
journal_title：Peptides
pub_type： 杂志文章,评审
doi：10.1016/j.peptides.2015.04.009
更新日期：2015-07-01 00:00:00
abstract：:ACTH/MSH(4-10) (10 micrograms/kg/b.i.d.; IP), administered to pregnant Sprague-Dawley rats during gestational days (GD) 3 to 12, significantly increased the metabolic activity of extensor digitorum longus (EDL) muscle at postnatal day 14. ACTH/MSH peptide, administered from day of birth to postnatal day 13, had no eff...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(90)90128-r
更新日期：1990-01-01 00:00:00
abstract：:The distribution of galanin-like immunoreactivity in the brain of the dogfish Scyliorhinus canicula was investigated using the indirect immunofluorescence technique. In the telencephalon, positive cells and fibers were located in the mid-caudal part of the area superficialis basalis, the n. septi caudoventralis and in...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(91)90025-k
更新日期：1991-03-01 00:00:00
abstract：:Honeybee stings are a severe public health problem. Bee venom contains a series of active components, including enzymes, peptides, and biogenic amines. The local reactions observed after envenoming include a typical inflammatory response and pain. Honeybee venom contains some well-known polycationic peptides, such as ...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2014.07.004
更新日期：2014-09-01 00:00:00
abstract：:Inferences regarding biosynthesis of LHRH in rats are made from immunocytochemical studies using LHRH antisera with varied and specific binding requirements. Immunoreactive perikarya were observed with antisera that could bind putative large molecular weight precursors of LHRH. No cells were detected with an antiserum...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(83)90096-7
更新日期：1983-11-01 00:00:00
abstract：:The release of peptides immunoreactive for a synthetic peptide (V-9-M) contained in the amino-terminal of pro-CCK was examined. The potassium-evoked release of V-9-M immunoreactive peptides from rat cerebral cortical slices in vitro was calcium dependent. Cholecystokinin-secreting rat medullary thyroid carcinoma cells...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(92)90011-q
更新日期：1992-11-01 00:00:00
abstract：:The monoclonal antibody 2F5 recognizing the neutralizing epitope ELDKWA on the C-domain could neutralize 90% of the investigated HIV-1 isolates. Low levels of ELDKWA-epitope-specific antibodies were observed in HIV-1-infected individuals. To induce high levels of antibodies to ELDKW-epitope, C-domain peptide (P2) was ...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/s0196-9781(00)00179-0
更新日期：2000-04-01 00:00:00
abstract：:Radiation enteritis occurs as a response to abdominal radiation, which can cause mucosal damage in the gastrointestinal mucosal epithelium. The small intestine is one of the most radiosensitive organs in the abdomen. The present study was undertaken to investigate the effect of octreotide (OCT) administration on heme ...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2005.11.012
更新日期：2006-06-01 00:00:00
abstract：:This review describes the role of modulation of intracellular adhesion molecule-1 (ICAM-1)/leukocyte function-associated antigen-1 (LFA-1) interaction in controlling autoimmune diseases or inducing immunotolerance. ICAM-1/LFA-1 interaction is essential for T-cell activation as well as for migration of T-cells to targe...
journal_title：Peptides
pub_type： 杂志文章,评审
doi：10.1016/s0196-9781(03)00083-4
更新日期：2003-03-01 00:00:00
abstract：:Atriopeptins are circulating peptide hormones which are secreted by atrial tissue and act at the kidney. Because the atriopeptins survive passage through the pulmonary circulation, they also may be involved in the modulation of airway or pulmonary vascular smooth muscle tone. Using in vitro organ bath techniques, atri...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(85)90159-7
更新日期：1985-07-01 00:00:00
abstract：:Using autoradiographic method and 125I-Tyro rat CGRP as a ligand, receptor binding sites were demonstrated in the rat central nervous system. Saturation studies and Scatchard analysis of CGRP-binding to slide mounted tissue sections containing primarily cerebellum showed a single class of receptors with a dissociation...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(85)90331-6
更新日期：1985-09-01 00:00:00
abstract：:To determine if insulin-like growth factor (IGF)-1 and -2, FSH, or leptin alter IGF-binding protein (IGFBP)-2, -3, -4, and -5 mRNA levels in bovine granulosa and (or) theca cells, granulosa and theca cells were collected from bovine ovarian follicles, plated for 48 h in 10% FCS and then treated for 24 h in serum-free ...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2004.07.008
更新日期：2004-12-01 00:00:00
abstract：:C-type natriuretic peptide (CNP) is assuming increasing importance in cardiovascular disease, and in adults its plasma levels are related to clinical and functional disease severity. Data are scarce regarding the reference values for CNP in infancy. Aim of this study was to assess the reference intervals for CNP in hu...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2011.11.005
更新日期：2012-01-01 00:00:00
abstract：:Cellular uptake of [125I] labelled DSIP at the luminal interface of the blood-brain barrier (BBB) was studied in the ipsilateral perfused in situ guinea pig forebrain. Regional unidirectional transfer constants (Kin) calculated from the multiple-time brain uptake analysis were 0.93, 1.33 and 1.66 microliter.min-1 g-1 ...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(89)90026-0
更新日期：1989-03-01 00:00:00
abstract：:As a class of peptides with 10 cysteine residues (-C-CC-C-CC-C-C-C-C-), D-superfamily conotoxins (D-conotoxins) can specifically act on nicotinic acetylcholine receptors (nAChRs). According to the conserved signal peptides of D-conotoxins, seven D-conotoxin precursor sequences with a previously undescribed Cys arrange...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2017.06.008
更新日期：2017-08-01 00:00:00
abstract：:Originally characterized in terms of its gastric acid inhibitory properties, GIP (gastric inhibitory polypeptide) expressed in the upper small intestine, was subsequently shown to exert strong glucose-dependent insulin-releasing properties. This action is generally attributed to GIP(1-42) and, so far, no evidence for ...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(95)00090-7
更新日期：1995-01-01 00:00:00
abstract：:We applied computational biology to identify the linear amino acid sequence recognized by a mouse monoclonal antibody raised against the full length HPV16 E7 oncoprotein. Computer-assisted search for the epitopic peptide used two parameters: the capability of E7 peptides to bind to MHC class II molecules, and the simi...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/s0196-9781(01)00539-3
更新日期：2001-12-01 00:00:00
abstract：:Higher plasma copeptin level has been associated with poor outcomes of critical illness. The present study was undertaken to investigate the plasma copeptin concentrations in children with traumatic brain injury (TBI) and to analyze the correlation of copeptin with disease outcome. Plasma copeptin concentrations of 12...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2013.01.015
更新日期：2013-04-01 00:00:00
abstract：:This paper reviews aspects of our research, focusing on the role of the melanocortin system in the central regulation of feeding and energy balance, which was begun in 1997. It describes data from successive physiological studies, concerning the identity of the appetite-regulating melanocortin receptor, melanocortin-4...
journal_title：Peptides
pub_type： 杂志文章,评审
doi：10.1016/j.peptides.2005.01.030
更新日期：2006-02-01 00:00:00
abstract：:Vasopressin is one of the key regulators of the body's water and solute balance. When this balance is pathologically disturbed, determination of serum vasopressin concentrations might be a helpful tool for guiding therapy. However, due to its instability and considerable association to platelets, reliable measurement ...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2005.04.019
更新日期：2005-12-01 00:00:00
abstract：:Numerous substance P (SP) immunoreactive nerve fibers were located around submucosal glands in the guinea pig nasal mucosa. Since these SP positive nerve fibers were also positive for vasoactive intestinal polypeptide, and to a lessor extent for neuropeptide Y, they were presumed to be parasympathetic fibers. SP recep...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/s0196-9781(98)00100-4
更新日期：1998-01-01 00:00:00
abstract：:The ability of acute exercise to stimulate appetite and food intake depends on intensity, duration, and agouti-related protein (AGRP) levels. Fasting, as well as any negative energy balance, has been reported to increase AGRP expression in the arcuate nucleus (ARC) of the hypothalamus and other extra-hypothalamic tiss...
journal_title：Peptides
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.peptides.2007.02.004
更新日期：2007-05-01 00:00:00
abstract：:We examined the effect of adjuvant arthritis on the content of immunoreactive calcitonin gene-related peptide (iCGRP) in the dorsal root ganglia at L4-L6 levels and the spinal cord at a lumbar level in rats. Arthritis was induced by inoculating adjuvant into both hind-paws twice at a 10 day interval. In the arthritic ...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(89)90057-0
更新日期：1989-03-01 00:00:00
abstract：:We have studied the in vitro effect of VIP and histamine on ultrastructure of the parietal cells in isolated guinea pig fundic glands. The morphological changes induced by histamine in the parietal cells can be compared to those observed after histamine stimulation in vivo or in vitro on gastric mucosa preparations. I...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(84)90219-5
更新日期：1984-03-01 00:00:00
abstract：:In the cephalopod mollusk Octopus vulgaris, the gonadotropic hormone released by the optic gland controls sexual maturity. Several lobes of the central nervous system control the activity of this gland. In one of these lobes, the olfactory lobe, a gonadotropin releasing hormone (GnRH) neuronal system has been describe...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2008.07.007
更新日期：2009-03-01 00:00:00
abstract：:Dermorphins are potent opiate-like peptides isolated from the skin of some species of frogs. They are characterized by the presence of a D-amino acid residue, which is crucial for bioactivity. A number of analogues were prepared in order to evaluate the structure-activity relationships. The syntheses were accomplished...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/s0196-9781(81)80117-9
更新日期：1981-10-01 00:00:00
abstract：:Neuromedin B (NMB), which was originally isolated from porcine spinal cord, is a mammalian bombesin-related peptide that exerts various physiological effects. Previously, we observed expression of NMB in rib cartilage from chicken. Here, we report the initial attempt to elucidate the role of NMB in cartilage. We used ...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2012.05.010
更新日期：2012-08-01 00:00:00
abstract：:The distribution of neurokinin B (NKB) was determined by immunocytochemistry with antisera directed toward its amino terminus. Immunoreactive perikarya were detected in the main and accessory olfactory bulbs, cortical regions, the olfactory tubercle, the bed nucleus of the stria terminalis, the diagonal band of Broca,...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/0196-9781(92)90192-6
更新日期：1992-07-01 00:00:00
abstract：:Which of Y1-Y5 receptors (Rs) mediate NPY's angiogenic activity was studied using Y2R-null mice and R-specific antagonists. In Y2R-null mice, NPY-induced aortic sprouting and in vivo Matrigel capillary formation were decreased by 50%; Y1R-antagonist blocked the remaining response. NPY-induced sprouting was equally inh...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/s0196-9781(02)00281-4
更新日期：2003-01-01 00:00:00
abstract：:Sympathetic neurotransmitter neuropeptide Y (NPY) is associated with vascular remodelling, neointimal hyperplasia and atherosclerosis in experimental animal models and clinical studies. In order to study the role of sympathetic nerve-produced NPY in vascular diseases, transgenic mouse model overexpressing NPY in centr...
journal_title：Peptides
pub_type： 杂志文章
doi：10.1016/j.peptides.2008.12.009
更新日期：2009-04-01 00:00:00
