Abstract:
:Courtship suppression is an associative conditioning procedure in Drosophila melanogaster that is ethologically based and capable of being tested on individual flies. We have expanded the range of the courtship conditioning by developing an excitatory procedure in which male flies learn to associate a novel odor with the courtship stimulating cues of virgin females. Wild-type males normally court other mature males very little, but following training, the odor alone is able to elicit increased levels of courtship towards an object male. Flies expressing an inhibitor of calcium/calmodulin-dependent protein kinase II (CaMKII) were previously shown to have no retention one hour after training in the courtship suppression task, as manifested in their persistent courting of a virgin female. A possible trivial explanation for this response is that the CaMKII-inhibited fly strains (ala1 and ala2) were merely hyperactive courters. The poor performance of these mutants in the new excitatory conditioning procedure confirms that their conditioning deficit results from a disruption of an associative mechanism per se.
journal_name
J Neurogenetjournal_title
Journal of neurogeneticsauthors
Broughton SJ,Tully T,Greenspan RJsubject
Has Abstractpub_date
2003-01-01 00:00:00pages
91-102issue
1eissn
0167-7063issn
1563-5260pii
1EEXM57F8JFBX41Tjournal_volume
17pub_type
杂志文章abstract::A new autosomal recessive mutation, characterized by an early defect in righting reflex and stiffened gait, progression to severe spasticity, tremor and rigidity, and death before weaning, appeared spontaneously on the C57BL/6 background. It was shown to be an allele of the mutant spastic spa, and shall be known as sp...
journal_title:Journal of neurogenetics
pub_type: 杂志文章
doi:
更新日期:1987-08-01 00:00:00
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journal_title:Journal of neurogenetics
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journal_title:Journal of neurogenetics
pub_type: 杂志文章
doi:
更新日期:1987-12-01 00:00:00
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journal_title:Journal of neurogenetics
pub_type: 杂志文章
doi:10.3109/01677068409107092
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journal_title:Journal of neurogenetics
pub_type: 杂志文章
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journal_title:Journal of neurogenetics
pub_type: 杂志文章,评审
doi:10.1080/01677060802610604
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journal_title:Journal of neurogenetics
pub_type: 杂志文章
doi:10.3109/01677069509083460
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journal_title:Journal of neurogenetics
pub_type: 杂志文章
doi:10.1080/01677063.2016.1238916
更新日期:2016-01-01 00:00:00
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journal_title:Journal of neurogenetics
pub_type: 杂志文章
doi:10.3109/01677060009084494
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journal_title:Journal of neurogenetics
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journal_title:Journal of neurogenetics
pub_type: 杂志文章,评审
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journal_title:Journal of neurogenetics
pub_type: 杂志文章
doi:10.3109/01677068609106848
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journal_title:Journal of neurogenetics
pub_type: 杂志文章
doi:10.3109/01677068509101424
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journal_title:Journal of neurogenetics
pub_type: 传,历史文章,杂志文章
doi:10.3109/01677063.2011.647144
更新日期:2012-03-01 00:00:00
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journal_title:Journal of neurogenetics
pub_type: 杂志文章
doi:10.3109/01677069609107063
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journal_title:Journal of neurogenetics
pub_type: 杂志文章
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journal_title:Journal of neurogenetics
pub_type: 杂志文章
doi:10.3109/01677068609106846
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journal_title:Journal of neurogenetics
pub_type: 杂志文章,评审
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pub_type: 杂志文章
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更新日期:2007-10-01 00:00:00
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journal_title:Journal of neurogenetics
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journal_title:Journal of neurogenetics
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journal_title:Journal of neurogenetics
pub_type: 杂志文章,评审
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abstract::Abstract: Nuclear factor of activated T cells (NFAT) is a calcium-responsive transcription factor. We describe here an NFAT-based neural tracing method-CaLexA (calcium-dependent nuclear import of LexA)-for labeling active neurons in behaving animals. In this system, sustained neural activity induces nuclear import of ...
journal_title:Journal of neurogenetics
pub_type: 杂志文章
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journal_title:Journal of neurogenetics
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
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journal_title:Journal of neurogenetics
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更新日期:2013-09-01 00:00:00
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journal_title:Journal of neurogenetics
pub_type: 杂志文章,评审
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更新日期:2016-01-01 00:00:00
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pub_type: 杂志文章
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journal_title:Journal of neurogenetics
pub_type: 杂志文章
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更新日期:2020-09-01 00:00:00
abstract::Abstract: This essay is dedicated to Obaid on the occasion of his 80th birthday. We both worked on the behavior of Drosophila and on what underlies behavior in the fly brain. Is that the fly's mind? The essay is about some limitations of brain science. It is just a little piece of writing. It is meant to honor Obaid f...
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pub_type: 历史文章,杂志文章
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更新日期:2012-09-01 00:00:00