Abstract:
:When individuals are exposed to stressful environmental challenges, the response varies widely in one or more of three components: psychology, behavior and physiology. This variability among individuals can be defined as temperament. In recent years, an increasing large body of evidence suggests that the dimensions of temperament, as well as personality, psychological disorders and behavioral traits, are influenced by genetic factors, and much of the variation appears to involve variation in genes or gene polymorphisms in the hypothalamic-pituitary-adrenocortical (HPA) axis and the behavior-controlling neurotransmitter networks. Here, we review our current understanding of the probabilistic impact of a number of candidate gene polymorphisms that control temperament, psychological disorders and behavioral traits in animals and human, including the gene polymorphisms related to corticotrophin-releasing hormone (CRH) production and adrenal cortisol production involved in the HPA axis, and a large number of gene polymorphisms in the dopaminergic and serotonergic neurotransmitter networks. It will very likely to assist in diagnosis and treatment of human relevant disorders, and provide useful contributions to our understanding of evolution, welfare and conservation, for animals in the wild and in production systems. Additionally, investigations of gene-gene and gene-environment complex interactions in humans and animals need further clear illustration.
journal_name
J Neurogenetjournal_title
Journal of neurogeneticsauthors
Qiu X,Martin GB,Blache Ddoi
10.1080/01677063.2017.1324857subject
Has Abstractpub_date
2017-01-01 00:00:00pages
1-16issue
1-2eissn
0167-7063issn
1563-5260journal_volume
31pub_type
杂志文章,评审abstract::Predictions from the theory of transfection, Karl-Friedrich Fischbach's first paper, were confirmed 20 years later. Also a model, proposed already in 1977 by Karl-Friedrich and colleagues, to explain the nonmonotonous dependence on light intensity of phototaxis in Drosophila, finds support in recent studies of functio...
journal_title:Journal of neurogenetics
pub_type: 杂志文章
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journal_title:Journal of neurogenetics
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journal_title:Journal of neurogenetics
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journal_title:Journal of neurogenetics
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journal_title:Journal of neurogenetics
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abstract::The development of the olfactory sense organs on the antenna of the fruit fly Drosophila utilises mechanisms distinct from those used in the rest of the adult peripheral nervous system. Lozenge (lz) is the only locus hither-to identified as required for the development of antennal sense organs. In addition to effects ...
journal_title:Journal of neurogenetics
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journal_title:Journal of neurogenetics
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journal_title:Journal of neurogenetics
pub_type: 历史文章,杂志文章
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journal_title:Journal of neurogenetics
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journal_title:Journal of neurogenetics
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journal_title:Journal of neurogenetics
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journal_title:Journal of neurogenetics
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journal_title:Journal of neurogenetics
pub_type: 杂志文章,评审
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abstract::Abstract: Nuclear factor of activated T cells (NFAT) is a calcium-responsive transcription factor. We describe here an NFAT-based neural tracing method-CaLexA (calcium-dependent nuclear import of LexA)-for labeling active neurons in behaving animals. In this system, sustained neural activity induces nuclear import of ...
journal_title:Journal of neurogenetics
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journal_title:Journal of neurogenetics
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journal_title:Journal of neurogenetics
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journal_title:Journal of neurogenetics
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