Abstract:
:The development of the olfactory sense organs on the antenna of the fruit fly Drosophila utilises mechanisms distinct from those used in the rest of the adult peripheral nervous system. Lozenge (lz) is the only locus hither-to identified as required for the development of antennal sense organs. In addition to effects on the antenna, mutations in lz also affect the development of the eye and maxillary palp. We have used the readily-scored eye-phenotype in a temperature sensitive lz allele to screen for dominant modifiers of phenotypes at this locus. We analyse the phenotypes of both intragenic and extragenic modifiers. Our results reinforce the view from developmental studies that lz functions in eye and antennal development in distinct ways.
journal_name
J Neurogenetjournal_title
Journal of neurogeneticsauthors
Gupta BP,Rodrigues Vdoi
10.3109/01677069509083460subject
Has Abstractpub_date
1995-12-01 00:00:00pages
137-51issue
3eissn
0167-7063issn
1563-5260journal_volume
10pub_type
杂志文章abstract::Based on unbeatable genetic accessibility and relative simplicity, the Drosophila larval neuromuscular junction has become a widely used model system for studying functional and structural aspects of excitatory glutamatergic synapses. Membrane-associated guanylate kinase-like proteins (MAGUKs) are first-order scaffold...
journal_title:Journal of neurogenetics
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journal_title:Journal of neurogenetics
pub_type: 历史文章,杂志文章
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journal_title:Journal of neurogenetics
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更新日期:1989-09-01 00:00:00