Human anti-pneumococcal polysaccharide antibodies are secreted by the CD5- B cell lineage.

abstract：:The clinical outcome of Leishmania pathogenesis ranges from active skin lesions to fatal visceral dissemination and severely impaired T cell immunity. It is well established that a strong Th1 immune response is protective against cutaneous forms of the disease, however a mixed Th1/Th2 response is most commonly observe...

journal_title：Cellular immunology

authors： Banerjee A,Bhattacharya P,Joshi AB,Ismail N,Dey R,Nakhasi HL

更新日期：2016-11-01 00:00:00

abstract：:A low-virulence, agerminative strain of Candida albicans (PCA-2) is able to confer a high degree of nonspecific protection against subsequent challenge with highly virulent microorganisms in mice. In an attempt to better define the effect of PCA-2 vaccination on the immune system and the nature of the mechanisms invol...

journal_title：Cellular immunology

authors： Vecchiarelli A,Cenci E,Puliti M,Blasi E,Puccetti P,Cassone A,Bistoni F

更新日期：1989-12-01 00:00:00

abstract：:Experimental autoimmune encephalomyelitis (EAE) is an animal model for multiple sclerosis (MS), and is induced by immunization with disease-causative self-antigens such as myelin oligodendrocyte glycoprotein (MOG). We have previously reported that transplantation of MOG expressing thymic epithelial progenitors (TEPs) ...

journal_title：Cellular immunology

authors： Su M,Lin Y,Cui C,Tian X,Lu X,He Z,Lai L

更新日期：2017-12-01 00:00:00

abstract：:Psychological stress evokes rapid changes to the cardiovascular and neuroendocrine systems, responses that can become habituated following repeated exposure. This study, comprising of two phases, suggests that the immune system follows a similar trend. Phase 1: 15 healthy subjects (aged between 26 and 56years) provide...

journal_title：Cellular immunology

authors： Shelton-Rayner GK,Macdonald DW,Chandler S,Robertson D,Mian R

更新日期：2010-01-01 00:00:00

abstract：:Human K cells are able to lyse human lymphoblastoid B cells in the presence of specific anti-human immunoglobulin isotype antibodies. The human lymphoblastoid B-cell line DAUDI (surface mu- and kappa-chains positive) was lysed in the presence of anti-mu and anti-kappa antisera, or IgG fraction of these antisera, and B...

journal_title：Cellular immunology

authors： Caraux J,Weigle WO

更新日期：1983-03-01 00:00:00

abstract：:In view of the eminently important role of interleukin-2 (IL-2) in T-cell responses, and in view of reports about immune stimulatory effects of PGE2, we reinvestigated the question whether PGE2 inhibits IL-2 production. It was found that PGE2 does not inhibit IL-2 production in murine spleen cell cultures after optima...

journal_title：Cellular immunology

authors： Wolf M,Falk W,Männel D,Dröge W

更新日期：1985-01-01 00:00:00

abstract：:Anti-TNF-α therapies have been applied in RA treatment, but the regulatory effect of the drug on immune system is not clear. In this study, we included 33 active RA patients and divided them into two groups. One group received anti-TNF-α mAb+methotrexate for 24 weeks, the other group got placebo+methotrexate for the f...

journal_title：Cellular immunology

authors： Huang Z,Yang B,Shi Y,Cai B,Li Y,Feng W,Fu Y,Luo L,Wang L

更新日期：2012-09-01 00:00:00

abstract：:The immediate effects and mechanisms of desensitization of contact sensitivity to 2,4-dinitro-1-fluorobenzene (DNFB) were investigated. Mice were sensitized with DNFB, desensitized with antigen 2 weeks later, and challenged 1 day after desensitization. Significant inhibition (approximately 50%) of contact sensitivity ...

journal_title：Cellular immunology

authors： Mekori YA,Claman HN

更新日期：1984-11-01 00:00:00

abstract：:In an attempt to better relate specific membrane characteristics of human adult and cord blood lymphocytes to specific functional activities, the phenotypic differences that exist in these two populations have been examined. Cord blood cells have considerably more spontaneous suppressor cell activity than adult cells....

journal_title：Cellular immunology

authors： Johnson C,Dwyer JM

更新日期：1983-10-01 00:00:00

abstract：:The transfer of B cells from mice immunized with Type III pneumococcal polysaccharide (SSS-III) results in the activation of suppressor and amplifier T cells that control the magnitude of the antibody response in recipient mice, immunized subsequently with SSS-III. Prior treatment of transferred B cells with an excess...

journal_title：Cellular immunology

authors： Baker PJ,Taylor C,Fauntleroy MB,Stashak PW,Prescott B

更新日期：1985-12-01 00:00:00

abstract：:The incubation of murine splenocytes in recombinant interleukin 2 (IL-2) gives rise to both lymphokine-activated killer (LAK) cells capable of lysing fresh tumor cells and cells capable of mediating antibody-dependent cellular cytotoxicity (ADCC) in the presence of anti-H2 allosera. A similarity between these two IL-2...

journal_title：Cellular immunology

authors： Eisenthal A,Shiloni E,Rosenberg SA

更新日期：1988-09-01 00:00:00

abstract：:Interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-alpha) are major proinflammatory cytokines inducing the synthesis and release of many inflammatory mediators. They are involved in immune regulation, autoimmune diseases, and inflammation. Acanthoic acid, (-)-pimara-9(11),15-dien-19-oic acid, is a pimaradiene d...

journal_title：Cellular immunology

authors： Kang HS,Kim YH,Lee CS,Lee JJ,Choi I,Pyun KH

更新日期：1996-06-15 00:00:00

abstract：:Activated macrophages are known to release a variety of immunoregulatory substances including the low-molecular-weight substances hydrogen peroxide and lactate. We report here that lactate but not hydrogen peroxide is capable of supporting a substantial production of T-cell growth factor (TCGF) in cultures of accessor...

journal_title：Cellular immunology

authors： Roth S,Dröge W

更新日期：1987-09-01 00:00:00

abstract：:Study of primary immune responses in leprosy has been limited, since disease becomes manifest long after infection or is not detectable. To study primary immune responses, we immunized in vitro human peripheral blood mononuclear cells from unexposed individuals using phenolic glycolipid 1 (PGL-1), an important water-i...

journal_title：Cellular immunology

authors： Schauf V,Holobaugh P,Miller P,Mittal K

更新日期：1991-10-01 00:00:00

abstract：:Some further aspects of B-lymphocyte-promotor factor (B-LPF) activity have been studied. This activity was present in the supernatants of certain helper-T-cell lines, and it induced polyclonal activation of Ig+ B cells into Ig-secreting cells. It was found that B-LPF induced polyclonal, terminal B-cell differentiation...

journal_title：Cellular immunology

authors： Reininger L,Fueri J,Boned A,Prat M,Landolfo S,Rubin B

更新日期：1985-04-15 00:00:00

abstract：:Sialoadhesin (Sn) is a surface receptor expressed on macrophages in steady state conditions, but during inflammation, Sn can be upregulated both on macrophages and on circulating monocytes. It was shown for different species that Sn becomes internalized after binding with monoclonal antibodies. These features suggest ...

journal_title：Cellular immunology

authors： De Schryver M,Cappoen D,Elewaut D,Nauwynck HJ,Maes L,Caljon G,Cos P,Delputte PL

更新日期：2017-02-01 00:00:00

abstract：:CD40 and its ligand (CD40L) regulate several cellular functions, including T and B-cell activation. The soluble form of CD40 (sCD40) antagonizes CD40/CD40L interaction. Patients undergoing hemodialysis (HD) present elevated sCD40 serum levels, which underlying molecular mechanisms are unknown. We studied sCD40 serum a...

journal_title：Cellular immunology

authors： Esposito P,Rampino T,Gregorini M,Gabanti E,Bianzina S,Dal Canton A

更新日期：2012-07-01 00:00:00

abstract：:Murine histocompatibility antigens were solubilized from the spleens and lungs of C57BL/6 (H-2b) animals with hypertonic salt (3 M KC1). Aggregate-free soluble antigens were incubated with nonadherent lymph node cells from BALB/c (H-2d) mice for 18 hr prior to their use as responder cells in the mixed-lymphocyte react...

journal_title：Cellular immunology

authors： Long PM,Sommer CV,Kong YM

更新日期：1983-06-01 00:00:00

abstract：:A B lymphoblastoid cell line can provide a comitogenic, accessory signal for mitogen-treated T cells. In a study evaluating the antigenic determinant of such cells that mediate this effect, a monoclonal antibody (I57) was raised against the Daudi cell line. This antibody was found to interact with a 30-kDa protein on ...

journal_title：Cellular immunology

authors： Hardy B,Dotan D,Novogrodsky A

更新日期：1989-01-01 00:00:00

abstract：:Previous studies have validated the capacity of classical (HLA-A,B,C) and nonclassical (HLA-G) MHC class I antigens expressed by target cells to influence natural killer (NK) cell-mediated cytolysis. Generally, elevated expression of these HLA class I molecules is correlated with enhanced resistance to lysis by NK cel...

journal_title：Cellular immunology

authors： Storkus WJ,Wei M,Cresswell P,Dawson JR

更新日期：1996-01-10 00:00:00

abstract：:Polyunsaturated fatty acid [omega-3 polyunsaturated fatty acids (omega-3PUFAs)] incorporation into cell membranes has been shown to have potent anti-inflammatory activity, though the mechanisms involved are only partially characterized. Here, we show that PUFA enrichment of T cell membranes decreased the overall expre...

journal_title：Cellular immunology

authors： Leid JG,Jutila MA

更新日期：2004-04-01 00:00:00

abstract：:Olopatadine hydrochloride is an H1-receptor-blocker but has other anti-allergic pharmacological potencies. We investigated whether olopatadine inhibits murine contact hypersensitivity, focussing on its modulatory action on epidermal Langerhans cells serving as antigen-presenting cells. While BALB/c mice were sensitize...

journal_title：Cellular immunology

authors： Tokura Y,Kobayashi M,Ito T,Takahashi H,Matsubara A,Takigawa M

更新日期：2003-07-01 00:00:00

abstract：:Viruses are related to the etiology of periodontitis. However, the role of viruses on Th17 cells infiltration in periodontitis lesions is unknown. Therefore, we examined the effects of TLR3 ligand on CCL20, which is related to Th17 cells migration, production in human gingival fibroblasts (HGFs). Polyinosinic-polycyti...

journal_title：Cellular immunology

authors： Hosokawa Y,Hosokawa I,Shindo S,Ozaki K,Matsuo T

更新日期：2013-05-01 00:00:00

abstract：:Curcumin has commonly been used for the treatment of various allergic diseases. However, its precise anti-allergic rhinitis effect and mechanism remain unknown. In the present study, the effect of curcumin on allergic responses in ovalbumin (OVA)-induced allergic rhinitis mouse was investigated. We explored the effect...

journal_title：Cellular immunology

authors： Zhang N,Li H,Jia J,He M

更新日期：2015-11-01 00:00:00

abstract：:Class I antigens are necessary for the recognition of tumor cells by cytotoxic T lymphocytes (CTL). The line 1 lung carcinoma is a spontaneous murine tumor deficient in class I antigen expression. Consistent with this, line 1 cells are highly metastatic in vivo. We investigated whether increasing class I antigen expre...

journal_title：Cellular immunology

authors： Cerosaletti KM,Blieden TM,Harwell LW,Welsh KM,Frelinger JG,Lord EM

更新日期：1990-05-01 00:00:00

abstract：:In this study the influence of a non-mitogenic anti-CD3 antibody on accessory cell-dependent antigen and mitogen-induced T-lymphocyte proliferation has been investigated. The antibody was found to completely inhibit PHA, Con A, PWM, and tetanus toxoid stimulation, with no effect on the proliferation induced by the cal...

journal_title：Cellular immunology

authors： Holter W,Majdic O,Stockinger H,Liszka K,Fischer G,Knapp W

更新日期：1986-06-01 00:00:00

abstract：:In nonactivated human monocytes, radiolabeled oleic, arachidonic, and palmitic acids are primarily incorporated into neutral lipids and phosphatidylcholine. Each of these fatty acids is also incorporated into phosphatidylethanolamine, phosphatidylserine, phosphatidylinositol, and sphingomyelin in characteristic propor...

journal_title：Cellular immunology

authors： Furlong ST,Mednis A,Remold HG

更新日期：1992-08-01 00:00:00

abstract：:The precise role of the granular enzyme A (granzyme A), a serine protease, in the lytic process of cytotoxic T lymphocytes (CTL) is not clear. We have recently constructed a CTL line transfected with the antisense gene of granzyme A (a-GrA). These a-GrA CTL had lower GrA activity as well as decreased lytic activities,...

journal_title：Cellular immunology

authors： Koo GC,Luk Y,Talento A,Wu J,Sirotina A,Fischer PA,Blake JT,Nguyen MP,Parsons W,Poe M

更新日期：1996-12-15 00:00:00

abstract：:Anti-CD3 mAb can activate T cells to help in B cell activation as detected by late events, such as maturation of B cells into Ig-secreting cells (IgSC), or by early events, such as B cell surface expression of the activation marker CD23. Two different anti-CD2 mAb each inhibited anti-CD3-induced T cell-dependent B cel...

journal_title：Cellular immunology

authors： Stohl W,Crow MK

更新日期：1990-10-15 00:00:00

abstract：:It has long been believed that mast cells play a crucial role in the development of many physiological changes during immediate allergic responses. This study was conducted to evaluate the anti-inflammation mechanism of Schizonepeta tenuifolia (ST) extract and ST purified chemicals on the PMA plus A23187-induced stimu...

journal_title：Cellular immunology

authors： Sohn SH,Cho S,Ji ES,Kim SH,Shin M,Hong M,Bae H

更新日期：2012-05-01 00:00:00