Myoblast-based cell transplantation.

abstract：:Obstructive sleep apnea (OSA) is increasingly recognized as a novel cardiovascular risk factor. OSA is implicated in the pathogenesis of hypertension, left ventricular dysfunction, coronary artery disease and stroke. OSA exerts its negative cardiovascular consequences through its unique pattern of intermittent hypoxia...

journal_title：Heart failure reviews

authors： Khayat R,Patt B,Hayes D Jr

更新日期：2009-09-01 00:00:00

abstract：:Anemia is common in Congestive Heart Failure (CHF) and is associated with an increased mortality, morbidity and progressive renal failure. The most common causes of the anemia in CHF are (1) the associated Chronic Kidney Disease (CKD), which causes depression of erythropoietin (EPO) production in the kidney, and (2) e...

journal_title：Heart failure reviews

authors： Silverberg DS

更新日期：2011-11-01 00:00:00

abstract：:To determine and address medication non-adherence is important and may improve patient outcomes. Our aim was to perform a systematic review on the operationalization of adherence measures in patients with heart failure using claims data. We searched the MEDLINE, EMBASE, and Cochrane databases. A quality check of the f...

journal_title：Heart failure reviews

authors： Krueger K,Griese-Mammen N,Schubert I,Kieble M,Botermann L,Laufs U,Kloft C,Schulz M

更新日期：2018-01-01 00:00:00

abstract：:The spectrum of ischemic heart diseases, encompassing acute myocardial infarction to heart failure, represents the leading cause of death worldwide. Although extensive progress in cardiovascular diagnoses and therapy has been made, the prevalence of the disease continues to increase. Cardiac regeneration has a promisi...

journal_title：Heart failure reviews

authors： Li H,Bao M,Nie Y

更新日期：2020-04-18 00:00:00

abstract：:Heart failure (HF) is a common complication in patients with type 2 diabetes and it is closely associated with high morbidity and mortality rate. The incidence of cardiovascular events in patients with diabetes is related to high levels of glycemia, expressed by increase of HbA1c levels. However, there is little evide...

journal_title：Heart failure reviews

authors： Palazzuoli A,Ceccarelli E,Ruocco G,Nuti R

更新日期：2018-05-01 00:00:00

abstract：:Genomic mechanisms of mineralocorticoid action have been increasingly elucidated over the past four decades. In renal epithelia, the main effect is an increase in sodium transport through activation and de novo synthesis of epithelial sodium channels. This leads to increased concentrations of intracellular sodium acti...

journal_title：Heart failure reviews

authors： Wehling M

更新日期：2005-01-01 00:00:00

abstract：:Healing after myocardial infarction (MI) is a well-orchestrated time-dependent process that involves inflammation, tissue repair with extracellular collagen matrix (ECCM) deposition and scar formation, and remodeling of myocardial structure, matrix, vasculature, and function. Rapid early ECCM degradation followed by s...

journal_title：Heart failure reviews

authors： Jugdutt BI

更新日期：2008-12-01 00:00:00

abstract：:β-Adrenergic receptors (βARs) belong to a large family of cell surface receptors known as G protein-coupled receptors (GPCRs). They are coupled to Gs protein (Gαs) for the activation of adenylyl cyclase (AC) yielding cyclic AMP (CAMP), and this provides valuable responses, which can affect the cardiac function such as...

journal_title：Heart failure reviews

authors： Ali DC,Naveed M,Gordon A,Majeed F,Saeed M,Ogbuke MI,Atif M,Zubair HM,Changxing L

更新日期：2020-03-01 00:00:00

abstract：:There is ongoing controversy regarding the association between loop diuretics (LD), especially in high doses, and adverse clinical outcomes in outpatients with heart failure (HF). We performed a systematic review of the evidence for LD in outpatients with HF. We searched MEDLINE, EMBASE, and Cochrane Clinical Trial Co...

journal_title：Heart failure reviews

authors： Kapelios CJ,Bonou Μ,Malliaras K,Athanasiadi E,Vakrou S,Skouloudi M,Masoura C,Barbetseas J

更新日期：2020-06-21 00:00:00

abstract：:Despite remarkable progress in the therapeutic approach of patients with chronic heart failure (CHF), exercise intolerance remains one of the hallmarks of the disease. During the past two decades, evidence has accumulated to underscore the key role of both endothelial dysfunction and skeletal muscle wasting in the pro...

journal_title：Heart failure reviews

authors： Conraads VM,Van Craenenbroeck EM,De Maeyer C,Van Berendoncks AM,Beckers PJ,Vrints CJ

更新日期：2013-01-01 00:00:00

abstract：:Due to the recent advances in diagnosis and management of patients with HER2-positive breast cancer, especially through novel HER2-targeted agents, cardiotoxicity becomes an emerging problem. Although chemotherapy significantly increases survival, the risk of cardiovascular disease development is high and still undere...

journal_title：Heart failure reviews

authors： Gonciar D,Mocan L,Zlibut A,Mocan T,Agoston-Coldea L

更新日期：2021-01-06 00:00:00

abstract：:Heart failure with preserved ejection fraction (HFpEF) accounts for almost one-half of all heart failure (HF) patients and continues to increase in prevalence. While mortality with heart failure with reduced ejection fraction (HFrEF) has decreased over the past few decades with use of evidence-based HFrEF therapy, mor...

journal_title：Heart failure reviews

authors： Moustafa A,Khan MS,Alsamman MA,Jamal F,Atalay MK

更新日期：2020-05-13 00:00:00

abstract：:Transthyretin amyloid cardiomyopathy (ATTR-CM) is a progressive, life-threatening disease characterized by deposition of insoluble amyloid fibrils in the myocardium, resulting in cardiac structural and functional abnormalities and ultimately heart failure. Disease frequency is reportedly lower in women than men, but s...

journal_title：Heart failure reviews

authors： Bruno M,Castaño A,Burton A,Grodin JL

更新日期：2021-01-01 00:00:00

abstract：:The abnormal regulation of nitric oxide synthase activity represents an underlying feature of heart failure. Increased peripheral vascular resistance, and decreased renal function may be in part related to impaired endothelium-dependent nitric oxide (NO) synthesis. Paradoxically, the chronic production of NO by induci...

journal_title：Heart failure reviews

authors： Calderone A

更新日期：2003-01-01 00:00:00

abstract：:Nitric oxide degradation linked to endothelial dysfunction plays a central role in cardiovascular diseases. Superoxide producing enzymes such as NADPH oxidase and xanthine oxidase are responsible for NO degradation as they generate a variety of reactive oxygen species (ROS). Moreover, superoxide is rapidly degraded by...

journal_title：Heart failure reviews

authors： de Gasparo M

更新日期：2002-10-01 00:00:00

abstract：:It is now clear that diastolic heart failure (DHF) is an important, perhaps even dominant form of heart failure in older Americans. However, our knowledge base regarding the epidemiology, pathophysiology, natural history, and therapy of this relatively recently recognized disorder is limited. A number of normal age re...

journal_title：Heart failure reviews

authors： Kitzman DW

更新日期：2002-01-01 00:00:00

abstract：:Heart failure is a complex disease process, the manifestation of various cardiac and noncardiac abnormalities. General treatment approaches for heart failure have remained the same over the past decades despite the advent of novel therapies and monitoring modalities. In the same vein, the readmission rates for heart f...

journal_title：Heart failure reviews

authors： Njoroge JN,Cheema B,Ambrosy AP,Greene SJ,Collins SP,Vaduganathan M,Mebazaa A,Chioncel O,Butler J,Gheorghiade M

更新日期：2018-07-01 00:00:00

abstract：:We aimed to study the cardiovascular and economic burden of diabetes mellitus (DM) in patients hospitalized for heart failure (HF) in the US and to assess the recent temporal trend. Data from the National Inpatient Sample were analyzed between 2005 and 2014. The prevalence of DM increased from 40.4 to 46.5% in patient...

journal_title：Heart failure reviews

authors： Mekhaimar M,Dargham S,El-Shazly M,Al Suwaidi J,Jneid H,Abi Khalil C

更新日期：2020-09-15 00:00:00

abstract：:Heart failure (HF) is characterized by the elaboration of a portfolio of pro-inflammatory cytokines and inflammatory mediators that are considered to contribute to disease progression by virtue of the deleterious effects that these molecules exert on the heart and circulation. Recent studies have suggested that these ...

journal_title：Heart failure reviews

authors： Bozkurt B,Mann DL,Deswal A

更新日期：2010-07-01 00:00:00

abstract：:Previous studies have reported superiority of mechanistic target-of-rapamycin (mTOR) antagonists (mTA) over calcineurin inhibitors (CNI) as part of maintenance immunosuppression (IS) in mitigating cardiac allograft vasculopathy (CAV) after heart transplantation (HT). MEDLINE and EMBASE were searched through October 20...

journal_title：Heart failure reviews

authors： Ueyama H,Kuno T,Takagi H,Alvarez P,Asleh R,Briasoulis A

更新日期：2020-05-18 00:00:00

abstract：:Loss of cardiomyocytes occurs with aging and contributes to cardiovascular complications. In the present study, we highlighted the role of clusterin, a protein that has recently been associated with the protection of cardiomyocytes from apoptosis. Clusterin protects cardiac cells against damage from myocardial infarct...

journal_title：Heart failure reviews

authors： Pereira RM,Mekary RA,da Cruz Rodrigues KC,Anaruma CP,Ropelle ER,da Silva ASR,Cintra DE,Pauli JR,de Moura LP

更新日期：2018-01-01 00:00:00

abstract：:Significant growth in the elderly population (age ≥ 65 years) with heart failure (HF) has taken place in developed countries and is occurring in most developing countries. Projections from population studies in the United States, Europe and other developed countries suggest that this trend will very likely continue an...

journal_title：Heart failure reviews

authors： Jugdutt BI

更新日期：2012-09-01 00:00:00

abstract：:In addition to functional alterations, heart failure has a structural basis as well. This concerns all components of the cardiac myocytes as well as the extracellular space. Proteins of the cardiomyocyte can be subdivided in 5 different categories: 1) Contractile proteins including myosin, actin, tropomyosin and the t...

journal_title：Heart failure reviews

authors： Kostin S,Hein S,Arnon E,Scholz D,Schaper J

更新日期：2000-10-01 00:00:00

abstract：:Ultrafiltration (UF) has emerged as an alternative therapy for acute decompensated heart failure (ADHF) due to its physiological benefits such as improvement in neurohormonal activation. We performed a systematic review and a meta-analysis to evaluate the efficacy, safety, and the impact on outcomes for UF therapy as ...

journal_title：Heart failure reviews

authors： Jain A,Agrawal N,Kazory A

更新日期：2016-09-01 00:00:00

abstract：:Congestive heart failure is most often caused by scar from coronary occlusion. The transition from occluded vessel to scar to dilation results in a remodeled ventricle that changes shape from ellipse to sphere. This shape change following an index event is called remodeling and a surgical approach for restoration (bri...

journal_title：Heart failure reviews

authors： Buckberg GD

更新日期：2004-10-01 00:00:00

abstract：:Although several risk factors including hypertension, cardiac hypertrophy, coronary artery disease, and diabetes are known to result in heart failure, elderly subjects are more susceptible to myocardial infarction and more likely to develop heart failure. This article is intended to discuss that cardiac dysfunction in...

journal_title：Heart failure reviews

authors： Dhalla NS,Rangi S,Babick AP,Zieroth S,Elimban V

更新日期：2012-09-01 00:00:00

abstract：:Cardiac fibrosis stems from the changes in the expression of fibrotic genes in cardiac fibroblasts (CFs) in response to the tissue damage induced by various cardiovascular diseases (CVDs) leading to their transformation into active myofibroblasts, which produce high amounts of extracellular matrix (ECM) proteins leadi...

journal_title：Heart failure reviews

authors： Gorabi AM,Hajighasemi S,Kiaie N,Rosano GMC,Sathyapalan T,Al-Rasadi K,Sahebkar A

更新日期：2020-09-01 00:00:00

abstract：:Sympathetic-parasympathetic interaction plays a major role in the evolution and outcome of many cardiovascular disorders. Nonetheless, a thorough understanding of this relationship and of its potential implications for prognosis and management still escapes many cardiologists. This article reviews the background of sy...

journal_title：Heart failure reviews

authors： Schwartz PJ,De Ferrari GM

更新日期：2011-03-01 00:00:00

abstract：:The discovery of cardiac natriuretic peptides two decades ago has lead to considerable research to investigate their biochemical and physiological properties. Clearly the heart is not just a pump but is also an endocrine organ that together with the kidneys control volume overload. The natriuretic peptides are a group...

journal_title：Heart failure reviews

authors： Azzazy HM,Christenson RH

更新日期：2003-10-01 00:00:00

abstract：:Diabetes and heart failure (HF) are both global epidemics with tremendous costs on society with increased rates of HF hospitalizations and worsened prognosis when co-existing, making it a significant "deadly duo." The evidence for pharmacological treatment of HF in patients with type 2 diabetes mellitus (T2DM) stems t...

journal_title：Heart failure reviews

authors： Ofstad AP,Atar D,Gullestad L,Langslet G,Johansen OE

更新日期：2018-05-01 00:00:00