Downregulation of islet hormone-sensitive lipase during long-term high-fat feeding.

abstract：:Apoptin, a small protein encoded by chicken anemia virus (CAV), induces cell death specifically in cancer cells. In normal cells, Apoptin remains in the cytoplasm; whereas in cancerous cells, it migrates into the nucleus and kills the cell. Cellular localization appears to be crucial. Through a yeast two-hybrid screen...

journal_title：Biochemical and biophysical research communications

authors： Huo DH,Yi LN,Yang J

更新日期：2008-07-18 00:00:00

abstract：:We have analyzed the cellular effects of nanosecond pulsed electrical fields on plant cells using fluorescently tagged marker lines in the tobacco cell line BY-2 and confocal laser scanning microscopy. We observe a disintegration of the cytoskeleton in the cell cortex, followed by contraction of actin filaments toward...

journal_title：Biochemical and biophysical research communications

authors： Berghöfer T,Eing C,Flickinger B,Hohenberger P,Wegner LH,Frey W,Nick P

更新日期：2009-09-25 00:00:00

abstract：:Two common non-steroidal anti-inflammatory drugs (NSAIDs) and their nitric oxide (NO) adducts were evaluated for effects on stomach and thymus. Following 4-h duration (acute) oral dosing of fasted male Wistar rats, 1.33 x 10(-4)mol/kg of ibuprofen caused significant visual irritation score and microscopic thinning, al...

journal_title：Biochemical and biophysical research communications

authors： Downing JE,Madden JC,Ingram MJ,Rostron C

更新日期：2005-08-26 00:00:00

abstract：:In this paper, we briefly review RRF (ribosome recycling factor, previously called ribosome releasing factor) (for recent reviews covering historical background see (1, 2)). ...

journal_title：Biochemical and biophysical research communications

authors： Kaji A,Teyssier E,Hirokawa G

更新日期：1998-09-08 00:00:00

abstract：:Lipases are widely present in various plants, animals and microorganisms, constituting a large category of enzymes. They have the ability to catalyze the cleavage of ester bonds. The lipase CinB from Enterobacter asburiae (E. asburiae) is an acetyl esterase. The primary amino acid sequence suggests that the EaCinB pro...

journal_title：Biochemical and biophysical research communications

authors： Shang F,Lan J,Liu W,Chen Y,Wang L,Zhao J,Chen J,Gao P,Ha NC,Quan C,Nam KH,Xu Y

更新日期：2019-11-05 00:00:00

abstract：:IL-17, which exerts strong pro-inflammatory effects, has emerged as an important mediator in inflammation-associated cancer. However, the characteristics of IL-17-producing cells, the relevance of IL-17 to clinical parameters and its function in the development and progression of colorectal carcinoma still remain to b...

journal_title：Biochemical and biophysical research communications

authors： Liu J,Duan Y,Cheng X,Chen X,Xie W,Long H,Lin Z,Zhu B

更新日期：2011-04-08 00:00:00

abstract：:Cysteine proteases have been identified in parasitic protozoa including the causative agent of Chagas' disease Trypanosoma cruzi. T. cruzi lysates subjected to substrate-containing SDS-polyacrylamide gel electrophoresis exhibit major bands of proteolytic activity in the 45-55 kDa molecular mass range (cruzipain activi...

journal_title：Biochemical and biophysical research communications

authors： Wiser MF,Lonsdale-Eccles JD,D'Alessandro A,Grab DJ

更新日期：1997-11-26 00:00:00

abstract：:8-Hydroxyguanine (8-OH-Gua) residues were formed in DNA of Ehrlich ascites cells exposed to the carcinogen 4-nitroquinoline 1-oxide. Formation of 8-OH-Gua was confirmed by chemical treatment of calf thymus DNA with the proximate metabolite of this carcinogen, 4-hydroxyaminoquinoline 1-oxide, together with seryl-adenos...

journal_title：Biochemical and biophysical research communications

authors： Kohda K,Tada M,Kasai H,Nishimura S,Kawazoe Y

更新日期：1986-09-14 00:00:00

abstract：:AtNPF7.3/AtNRT1.5, which is a nitrate transporter that drives root-to-shoot transport of NO3-, is also involved in modulating the response to K+ deprivation in Arabidopsis by affecting root development and K+ transport. However, whether NPF7.3/NRT1.5 functions in regulating plant responses to deficiencies of other nut...

journal_title：Biochemical and biophysical research communications

authors： Cui YN,Li XT,Yuan JZ,Wang FZ,Wang SM,Ma Q

更新日期：2019-01-01 00:00:00

abstract：:FKBP59-HBI, a heat shock protein hsp90-binding immunophilin that was originally detected in heterooligomer forms of steroid receptors, is retained on Calmodulin (CAM)-Sepharose 4B in the presence of 2 mM Ca2+ and is eluted by EGTA, demonstrating a specific p59-CAM interaction. The p59 amino acid sequence reveals the p...

journal_title：Biochemical and biophysical research communications

authors： Massol N,Lebeau MC,Renoir JM,Faber LE,Baulieu EE

更新日期：1992-09-30 00:00:00

abstract：:The Wnt/β-catenin signaling pathway controls cell proliferation and differentiation, and therefore, when this pathway is excessively activated, it causes tumorigenesis. Our chemical suppressor screening in zebrafish embryos identified antifungal azoles including clotrimazole, miconazole, and itraconazole, as Wnt/β-cat...

journal_title：Biochemical and biophysical research communications

authors： Yonezawa H,Ogawa M,Katayama S,Shimizu Y,Omori N,Oku Y,Sakyo T,Uehara Y,Nishiya N

更新日期：2018-11-17 00:00:00

abstract：:DNA bending has been shown to play a critical role in conservative site-specific DNA recombination reactions such as lambda integration. V(D)J recombination, the only mammalian site directed recombination system, is directed by recombinational signal sequences composed of heptamer, nonamer and spacer elements. The non...

journal_title：Biochemical and biophysical research communications

authors： Andrews R,Halligan NL,Halligan BD

更新日期：1993-05-28 00:00:00

abstract：:Because the expression of EBNA1 is prevalent in all EBV-associated tumors, it has become one of the most attractive drug targets for the discovery of anti-EBV compounds. In a cell-based reporter system, EBNA1 consistently upregulated the transcription of an oriP-Luc mini-EBV episome by 6- to 8-fold. The treatment of c...

journal_title：Biochemical and biophysical research communications

authors： Chen YL,Tsai HL,Peng CW

更新日期：2012-01-20 00:00:00

abstract：:Hyperphosphorylation of extracellular signal-regulated protein kinases-1/2 (ERK1/2) is known to promote cancer cell proliferation. We therefore investigated the constitutive phosphorylation levels of ERK1/2 and the expression of its downstream targets c-Fos, c-Jun, and cyclooxygenase-2 (COX-2) in biopsied human gastri...

journal_title：Biochemical and biophysical research communications

authors： Wu WK,Sung JJ,Yu L,Li ZJ,Chu KM,Cho CH

更新日期：2008-08-22 00:00:00

abstract：:In this study the sea bass (Dicentrarchus labrax) pepsinogen C gene was isolated. The nucleotide sequences of all exons are presented. The organization of the gene is compatible with that of other aspartic proteinases. The predicted 388-residue amino acid (aa) sequence of sea bass pepsinogen C consists of a signal seq...

journal_title：Biochemical and biophysical research communications

authors： Terova G,Rimoldi S,Larghi S,Bernardini G,Gornati R,Saroglia M

更新日期：2007-11-23 00:00:00

abstract：:A type II DNA topoisomerase has been partially purified from calf thymus mitochondria by a combination of differential centrifugation and column chromatography. The mitochondrial enzyme was inhibited by amsacrine (m-AMSA) slightly at 0.5 microM, significantly at 5.0 microM, and completely at 50 microM. A similar profi...

journal_title：Biochemical and biophysical research communications

authors： Lin JH,Castora FJ

更新日期：1991-04-30 00:00:00

abstract：:Ultrasound (US) has emerged as a promising noninvasive modality for neuromodulation. Despite previous evidence that US may mediate cellular response by activating mechanosensitive ion channels embedded in the cell membrane, the underlying mechanism is not well understood. In this work, we developed a vertically deploy...

journal_title：Biochemical and biophysical research communications

authors： Liao D,Li F,Lu D,Zhong P

更新日期：2019-10-20 00:00:00

abstract：:Porcine kidney betaine aldehyde dehydrogenase (EC 1.2.1.8) kinetic properties were determined at low substrate concentrations. The double-reciprocal plots of initial velocity versus substrate concentration are linear and intersect at the left of the 1/v axis and showed substrate inhibition with betaine aldehyde. Studi...

journal_title：Biochemical and biophysical research communications

authors： Figueroa-Soto CG,Valenzuela-Soto EM

更新日期：2000-03-16 00:00:00

abstract：:We present here the biosynthesis of AgNps from the aqueous extract of H. thebaica fruit, and monitored through UV-Vis spectrophotometer. The functional group were characterized through ATR-FTIR spectroscopy, the particle size, morphologies and elemental composition of the nanoparticles were investigated by using TEM, ...

journal_title：Biochemical and biophysical research communications

authors： Bello BA,Khan SA,Khan JA,Syed FQ,Mirza MB,Shah L,Khan SB

更新日期：2017-08-26 00:00:00

abstract：:The enantiomers of 7,12-dimethylbenz[a]anthracene (DMBA) 5,6-epoxide were directly resolved by normal-phase high-performance liquid chromatography with an ionically bonded chiral stationary phase. The absolute configurations of the resolved enantiomers were determined by comparison of circular dichroism spectra of the...

journal_title：Biochemical and biophysical research communications

authors： Mushtaq M,Weems HB,Yang SK

更新日期：1984-12-14 00:00:00

abstract：:Targeting mitochondrial respiration has been documented as an effective therapeutic strategy in cancer. However, the impact of mitochondrial respiration inhibition on cervical cancer cells are not well elucidated. Using a panel of cervical cancer cell lines, we show that an existing drug atovaquone is active against t...

journal_title：Biochemical and biophysical research communications

authors： Tian S,Chen H,Tan W

更新日期：2018-05-23 00:00:00

abstract：:The development of central nervous system (CNS) neuronal networks involves processes including neuroblast migration, axonal pathfinding, and synaptogenesis. To evaluate the role of the axonal guidance molecule DSCAM in CNS connectivity, we generated a lacZ reporter construct, Pr1.8-betagal, containing a 1.8kb fragment...

journal_title：Biochemical and biophysical research communications

authors： Barlow GM,Lyons GE,Richardson JA,Sarnat HB,Korenberg JR

更新日期：2002-11-22 00:00:00

abstract：:In this study, we demonstrate that in addition to T lymphocytes, human naïve eosinophils and the differentiated eosinophil-like cell line, AML14.3D10 express CCR8 and respond to CCL1 through CCR8 engagement. The responsiveness of cells was dependent on maturation stage, since CCL1 induced pronounced chemotaxis only in...

journal_title：Biochemical and biophysical research communications

authors： Karlsson AK,Walles K,Bladh H,Connolly S,Skrinjar M,Rosendahl A

更新日期：2011-04-22 00:00:00

abstract：:The organization of caveolae ultrastructures in the plasma membrane and the functions they dictate are mediated by membrane-embedded caveolins (caveolin-1, 2, 3) and peripherally attached cavins (cavin-1, 2, 3, 4). Mutations in caveolin and cavin genes are associated with a variety of human diseases. Cavin-1/PTRF muta...

journal_title：Biochemical and biophysical research communications

authors： Mohapatra A,Lokappa SB,Chaudhary N

更新日期：2020-01-15 00:00:00

abstract：:Ribosomal protein S6 phosphorylation is stimulated by a variety of hormones and growth factors. In mammalian cells the predominant S6 kinase is a 70 kDa enzyme which exists in two forms differing only in their amino terminal region. To determine whether this difference is functionally significant we have examined the ...

journal_title：Biochemical and biophysical research communications

authors： Coffer PJ,Woodgett JR

更新日期：1994-01-28 00:00:00

abstract：:We analyzed lesioned LDL in both atherosclerotic humans and in the apo E deficient (E degree) mice and compared its characteristics to plasma LDL. Lesioned LDL, in comparison to plasma LDL, was minimally oxidized and aggregated. Upon incubation of E degree-aortic lesions with 125[I]-labeled LDL, a time-dependent oxida...

journal_title：Biochemical and biophysical research communications

authors： Aviram M,Maor I,Keidar S,Hayek T,Oiknine J,Bar-El Y,Adler Z,Kertzman V,Milo S

更新日期：1995-11-13 00:00:00

abstract：:Neurons in the adult central nervous system (CNS) have a poor intrinsic axon growth potential after injury, but the underlying mechanisms are largely unknown. Wingless-related mouse mammary tumor virus integration site (WNT) family members regulate neural stem cell proliferation, axon tract and forebrain development i...

journal_title：Biochemical and biophysical research communications

authors： Duan RS,Liu PP,Xi F,Wang WH,Tang GB,Wang RY,Saijilafu,Liu CM

更新日期：2018-05-05 00:00:00

abstract：:The non-structural protein NS2B/NS3 serine-protease complex of the dengue virus (DENV) is required for the maturation of the viral polyprotein. Dissociation of the NS2B cofactor from NS3 diminishes the enzymatic activity of the complex. In this study, we identified a small molecule inhibitor that interferes with the i...

journal_title：Biochemical and biophysical research communications

authors： Pambudi S,Kawashita N,Phanthanawiboon S,Omokoko MD,Masrinoul P,Yamashita A,Limkittikul K,Yasunaga T,Takagi T,Ikuta K,Kurosu T

更新日期：2013-10-25 00:00:00

abstract：:HMGB1 is a conserved chromosomal protein composed of two DNA-binding domains and an acidic C-terminal tail. There were evidences suggesting that the C-terminal tail contributed to the DNA binding specificity of the N-terminal DNA-binding domains. However, the mechanism underlining this observation is largely unknown. ...

journal_title：Biochemical and biophysical research communications

authors： Wang Q,Zeng M,Wang W,Tang J

更新日期：2007-08-17 00:00:00

abstract：:Pancreatic elastase has been implicated in the pathophysiology of severe acute pancreatitis, characterized by systemic inflammatory response, distant organ failure, and high mortality. Here we show that pancreatic elastase activates transcription factors NF-kappaB, AP-1, and NFAT in human myeloid cells (U-937 and THP-...

journal_title：Biochemical and biophysical research communications

authors： Hietaranta A,Mustonen H,Puolakkainen P,Haapiainen R,Kemppainen E

更新日期：2004-10-08 00:00:00