Priming of measles virus-specific humoral- and cellular-immune responses in macaques by DNA vaccination.

abstract：BACKGROUND:Surveillance for acute flaccid paralysis with laboratory confirmation has been a key strategy in the global polio eradication initiative, and the laboratory platform established for polio testing has been expanded in many countries to include surveillance for cases of febrile rash illness to identify measles...

journal_title：Vaccine

authors： Cavallaro KF,Sandhu HS,Hyde TB,Johnson BW,Fischer M,Mayer LW,Clark TA,Pallansch MA,Yin Z,Zuo S,Hadler SC,Diorditsa S,Hasan AS,Bose AS,Dietz V,AMES Study Group.

更新日期：2015-02-25 00:00:00

abstract：:Previous work by our laboratory identified a fraction of Schistosoma mansoni soluble adult worm antigenic preparation, designated PIII, able to elicit significant in vitro cell proliferation, and lower in vitro and in vivo granuloma formation. In the present work, we investigated some biological activities of P24, an ...

journal_title：Vaccine

authors： Zouain CS,Gustavson S,Oliveira SC,Azevedo V,Alves JB,Goes AM

更新日期：2000-12-08 00:00:00

abstract：:There is a substantial need to develop better influenza virus vaccines that can protect populations that are not adequately protected by the currently licensed vaccines. While live attenuated influenza virus vaccines induce superior immune responses compared to inactivated vaccines, the manufacturing process of both t...

journal_title：Vaccine

authors： Kopecky-Bromberg SA,Fraser KA,Pica N,Carnero E,Moran TM,Franck RW,Tsuji M,Palese P

更新日期：2009-06-08 00:00:00

abstract：:This article presents the World Health Organization's (WHO) recommendations on the use of polio vaccine excerpted from the WHO position paper on polio vaccines - March 2016, published in the Weekly Epidemiological Record [1]. This position paper on polio vaccines replaces the 2014 WHO position paper [2]. The position ...

journal_title：Vaccine

authors： World Health Organization

更新日期：2017-03-01 00:00:00

abstract：:Ebola virus (EBOV) is among the deadliest pathogens known to man causing infrequent outbreaks of hemorrhagic disease. In humans, the case fatality rates in the outbreaks can reach 90%. During the West African epidemic almost 30,000 people were infected and of these over 11,000 fatalities were reported. Currently, we a...

journal_title：Vaccine

authors： Lehrer AT,Wong TS,Lieberman MM,Johns L,Medina L,Feldmann F,Feldmann H,Marzi A

更新日期：2019-11-08 00:00:00

abstract：:Severe diarrhea caused by rotavirus is a health problem worldwide, including Thailand. The World Health Organization has recommended incorporating rotavirus vaccination into national immunization programs. This policy has been implemented in several countries, but not in Thailand where the mortality rate is not high. ...

journal_title：Vaccine

authors： Muangchana C,Riewpaiboon A,Jiamsiri S,Thamapornpilas P,Warinsatian P

更新日期：2012-04-16 00:00:00

abstract：:A major challenge for poultry vaccination is the design of vaccines that protect against multiple pathogens via a single protective dose delivered through mass vaccination methods. In this investigation, we examined herpesvirus of turkeys (HVT) as a vaccine vector for delivery of haemagglutinin (HA) antigen of highly ...

journal_title：Vaccine

authors： Li Y,Reddy K,Reid SM,Cox WJ,Brown IH,Britton P,Nair V,Iqbal M

更新日期：2011-10-26 00:00:00

abstract：:The immunopotentiating activities of colloidal iron hydroxide, a novel, experimental mineral adjuvant, and of aluminium hydroxide. the licensed adjuvant for human vaccines, were compared. Our studies revealed that colloidal iron hydroxide and aluminium hydroxide behaved comparably with respect to supporting induction ...

journal_title：Vaccine

authors： Leibl H,Tomasits R,Brühl P,Kerschbaum A,Eibl MM,Mannhalter JW

更新日期：1999-03-05 00:00:00

abstract：:Immunization with amyloid-beta (Abeta) peptide reduces amyloid load in animal studies and in humans; however clinical trials resulted in the development of a pro-inflammatory cellular response to Abeta. Apoptosis has been employed to stimulate humoral and Th2-biased cellular immune responses. Thus, we sought to invest...

journal_title：Vaccine

authors： DaSilva KA,Brown ME,McLaurin J

更新日期：2009-02-25 00:00:00

abstract：:Prostatic acid phosphatase (PAP) is a prostate tumor antigen currently being investigated as a target antigen in several human vaccine trials, some with evidence of clinical benefit. We have previously demonstrated that plasmid DNA vaccines encoding either human or rat PAP can elicit antigen-specific cellular and humo...

journal_title：Vaccine

authors： Johnson LE,Frye TP,Arnot AR,Marquette C,Couture LA,Gendron-Fitzpatrick A,McNeel DG

更新日期：2006-01-16 00:00:00

abstract：:Modified Vaccinia virus Ankara (MVA) is an attenuated strain of vaccinia virus that is being considered as a safer alternative to replicating vaccinia vaccine strains such as Dryvax(®) and ACAM2000. Its excellent safety profile and large genome also make it an attractive vector for the delivery of heterologous genes f...

journal_title：Vaccine

authors： Hermanson G,Chun S,Felgner J,Tan X,Pablo J,Nakajima-Sasaki R,Molina DM,Felgner PL,Liang X,Davies DH

更新日期：2012-01-11 00:00:00

abstract：:Infectious bronchitis virus (IBV) as an avian coronavirus is still posing a persistent and imminent threat to the poultry industry worldwide. Here we report that transfection of Sf9 cells with a single recombinant baculovirus encoding M and S proteins resulted in the assembly of IBV VLPs; this is the first report that...

journal_title：Vaccine

authors： Liu G,Lv L,Yin L,Li X,Luo D,Liu K,Xue C,Cao Y

更新日期：2013-11-12 00:00:00

abstract：:The annual contact for influenza vaccination provides an opportunity to ensure that adults have received other recommended vaccines such as Tdap. Healthy 19-64 year-olds were randomized to receive concomitant administration of Tdap and influenza vaccines or influenza vaccine followed (in 4-6 weeks by) Tdap. 720 partic...

journal_title：Vaccine

authors： McNeil SA,Noya F,Dionne M,Predy G,Meekison W,Ojah C,Ferro S,Mills EL,Langley JM,Halperin SA

更新日期：2007-04-30 00:00:00

abstract：:Prior work shows that an attenuated West Nile virus (WNV), the nonstructural (NS)4B-P38G mutant infection in mice induced strong immune responses and protected host from subsequent lethal wild-type WNV infection. Here, we investigated NS4B-P38G mutant infection in myeloid differentiation factor 88-deficient (MyD88(-/-...

journal_title：Vaccine

authors： Xie G,Welte T,Wang J,Whiteman MC,Wicker JA,Saxena V,Cong Y,Barrett AD,Wang T

更新日期：2013-08-28 00:00:00

abstract：:The mechanisms of protection elicited by smallpox vaccine in humans have not been delineated. Dendritic cells (DCs) are the most potent of professional antigen presenting cells which on activation modulate both innate and adaptive immune responses. Immunogenic proteins of vaccinia virus have been identified with prote...

journal_title：Vaccine

authors： Agrawal S,Gupta S,Agrawal A

更新日期：2009-01-01 00:00:00

abstract：:Triton X-100 (TX-100) is the most common surfactant used to split viruses during the production of influenza split-virus vaccines. It is a mild surfactant not known to denature the viral proteins; this property makes TX-100 useful for maintaining antigen conformational structure, and, as an added benefit, for partiall...

journal_title：Vaccine

authors： Sahin Z,Neeleman R,Haines J,Kayser V

更新日期：2019-02-14 00:00:00

abstract：:ArtinM and Jacalin (JAC) are lectins from the jackfruit (Artocarpus integrifolia) that have important role in modulation of immune responses to pathogens. Neospora caninum is an Apicomplexa parasite that causes neuromuscular disease in dogs and reproductive disorders in cattle, with economic impact on the livestock in...

journal_title：Vaccine

authors： Cardoso MR,Mota CM,Ribeiro DP,Santiago FM,Carvalho JV,Araujo EC,Silva NM,Mineo TW,Roque-Barreira MC,Mineo JR,Silva DA

更新日期：2011-11-15 00:00:00

abstract：:Recently avian influenza A viruses of the H5N1 subtype were shown to infect humans in the Hong Kong area, resulting in the death of six people. Although these viruses did not efficiently spread amongst humans, these events illustrated that influenza viruses of subtypes not previously detected in humans could be at the...

journal_title：Vaccine

authors： Rimmelzwaan GF,Claas EC,van Amerongen G,de Jong JC,Osterhaus AD

更新日期：1999-03-17 00:00:00

abstract：:The long-term duration of recombinant hepatitis B vaccine-induced immunity among persons vaccinated starting at birth is still not well understood. Waning of vaccine-induced immunity could leave young adults at risk of hepatitis B virus infection due to behavioral or occupational exposures. We followed a cohort of chi...

journal_title：Vaccine

authors： Chaves SS,Fischer G,Groeger J,Patel PR,Thompson ND,Teshale EH,Stevenson K,Yano VM,Armstrong GL,Samandari T,Kamili S,Drobeniuc J,Hu DJ

更新日期：2012-02-21 00:00:00

abstract：OBJECTIVES:To determine the proportion of children whose parents prefer them to receive live, attenuated influenza vaccine (LAIV) or inactivated influenza vaccine (IIV), examine reasons for preferences, and determine what percentage of vaccinated children receive other than the preferred type of vaccine and why. METHO...

journal_title：Vaccine

authors： Santibanez TA,Kahn KE,Bridges CB

更新日期：2018-11-19 00:00:00

abstract：:Domestic ducks remain a major source of zoonotic Salmonella enterica infections for man worldwide and approaches to protection should include vaccine-mediated immunity. With this in mind we developed several genetically defined mutants in a virulent duck Salmonella typhimurium isolate TT-1. From initial tests for viru...

journal_title：Vaccine

authors： Tang T,Gao Q,Barrow P,Wang M,Cheng A,Jia R,Zhu D,Chen S,Liu M,Sun K,Yang Q,Chen X

更新日期：2015-10-13 00:00:00

abstract：:In the present study, cross-protection to bovine herpesvirus type 5 (BHV-5) induced by bovine herpesvirus type 1 (BHV-1) vaccination was examined following inoculation of rabbits and calves with a glycoprotein E (gE)-negative BHV-1 vaccine and subsequent challenge with BHV-5. Rabbits (n=5) and calves (n=8) were vaccin...

journal_title：Vaccine

authors： Silva AD,Spilki FR,Franco AC,Esteves PA,Hübner SO,Driemeier D,Oliveira AP,Rijsewijk F,Roehe PM

更新日期：2006-04-12 00:00:00

abstract：:Chagas' disease is a major tropical disease for which a cure for chronic phase does not exist yet. Trypanosoma cruzi trans-sialidase (TS) seems to be involved in relevant processes such as infectivity, host survival and, very importantly, disease pathogenesis. In this study, we show that mice vaccinated with an engine...

journal_title：Vaccine

authors： Fontanella GH,De Vusser K,Laroy W,Daurelio L,Nocito AL,Revelli S,Contreras R

更新日期：2008-05-02 00:00:00

abstract：:HIV-infected individuals have impaired immune responses to vaccines and high rates of pneumococcal disease. The effect of vitamin A and zinc supplementation on the immunogenicity of a 7-valent pneumococcal CRM-197 conjugate vaccine (PC-7) was evaluated in 118 HIV+ injection drug users. Subjects were randomized to oral...

journal_title：Vaccine

authors： Deloria-Knoll M,Steinhoff M,Semba RD,Nelson K,Vlahov D,Meinert CL

更新日期：2006-03-06 00:00:00

abstract：:The study evaluated the immunogenicity and efficacy of a trivalent subunit MF59-adjuvanted influenza vaccine (A/Wisconsin/67/05 (H3N2), A/Solomon Islands/3/06 (H1N1) and B/Malaysia/2506/04) in preventing serologically diagnosed infections in a group of 67 institutionalized elderly volunteers during 2007/2008 winter, c...

journal_title：Vaccine

authors： Camilloni B,Neri M,Lepri E,Basileo M,Sigismondi N,Puzelli S,Donatelli I,Iorio AM

更新日期：2010-11-03 00:00:00

abstract：:Staphylococcus aureus is a major human pathogen and many of the strains are resistant to conventional antibacterial treatment. The bacteria cause disease largely due to the production of multiple toxins, whose synthesis is controlled by an RNA molecule termed RNAIII. The production of RNAIII is induced by quorum sensi...

journal_title：Vaccine

authors： Yang G,Gao Y,Dong J,Xue Y,Fan M,Shen B,Liu C,Shao N

更新日期：2006-02-20 00:00:00

abstract：BACKGROUND:Expression of recombinant hemagglutinin (rHA) in insect cells represents a technology with proven efficacy in seasonal influenza and with the potential for a rapid response to the emergence of new, pandemic strains. We evaluated the safety and immunogenicity of rHA vaccine (H5/Indonesia/5/05) produced in SF+...

journal_title：Vaccine

authors： Treanor JJ,Essink B,Hull S,Reed S,Izikson R,Patriarca P,Goldenthal KL,Kohberger R,Dunkle LM

更新日期：2013-11-19 00:00:00

abstract：:The bioavailability of oseltamivir phosphate and oseltamivir carboxylate were assessed in healthy volunteers when delivered as a solution of the active pharmaceutical ingredient (API) compared with the commercial capsule formulation. The 90% confidence intervals (CIs) for the ratios of the two treatments (capsule vers...

journal_title：Vaccine

authors： Brewster M,Smith JR,Dutkowski R,Robson R

更新日期：2006-11-10 00:00:00

abstract：OBJECTIVES:HIV-infected children have poor responses to inactivated influenza vaccines. Live vaccines (LAIVs) are highly efficacious in children, but they are not used in HIV-infected children du e to limited information. We investigated the safety, immunogenicity and viral shedding of LAIV4 in HIV-infected compared wi...

journal_title：Vaccine

authors： Curtis D,Ning MF,Armon C,Li S,Weinberg A

更新日期：2015-09-11 00:00:00

abstract：:Immunization of pregnant women against influenza is a promising strategy to protect the mother, fetus, and young infant from influenza-related diseases. The burden of influenza during pregnancy, the vaccine immunogenicity during this period, and the robust influenza vaccine safety database underpin recommendations tha...

journal_title：Vaccine

authors： Ortiz JR,Neuzil KM,Ahonkhai VI,Gellin BG,Salisbury DM,Read JS,Adegbola RA,Abramson JS

更新日期：2012-11-26 00:00:00