Measurement of antibody responses to Modified Vaccinia virus Ankara (MVA) and Dryvax(®) using proteome microarrays and development of recombinant protein ELISAs.

abstract：:The immunogenicity of proteins encapsulated in poly(DL-lactide-co-glycolide) (PLG) microspheres has not been investigated to any extent in large animal models. In this study, IgG and IgA responses to ovalbumin (OVA), encapsulated in microspheres was investigated following intranasal inoculation into calves. Scanning e...

journal_title：Vaccine

authors： Kavanagh OV,Earley B,Murray M,Foster CJ,Adair BM

更新日期：2003-10-01 00:00:00

abstract：:Carcinoembryonic antigen (CEA), which is expressed in several cancer types, is a potential target for specific immunotherapy. In this study, the feasibility of using dendrite cells (DCs) for tumor immunotherapy after transduction with a recombinant adenovirus containing CEA gene (AdVCEA) was investigated. The recombin...

journal_title：Vaccine

authors： Cho HI,Kim HJ,Oh ST,Kim TG

更新日期：2003-12-12 00:00:00

abstract：:A family of parasite antigens known as Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is believed to play an important role in the binding of infected erythrocytes to host receptors in the micro-vasculature. Available data advocates the existence of a subset of very adhesive (rosetting, auto-agglutinati...

journal_title：Vaccine

authors： Chen Q,Pettersson F,Vogt AM,Schmidt B,Ahuja S,Liljeström P,Wahlgren M

更新日期：2004-07-29 00:00:00

abstract：:Pseudomonas aeruginosa is a common cause of infection in immunocompromised patients and is the major contributor to morbidity in individuals with cystic fibrosis (CF). The antibiotic resistance shown by this pathogen and morbidity in patients with chronic infection has encouraged investigations into the development of...

journal_title：Vaccine

authors： Thomas LD,Dunkley ML,Moore R,Reynolds S,Bastin DA,Kyd JM,Cripps AW

更新日期：2000-09-15 00:00:00

abstract：:The reactogenicity and immunogenicity of the administration of recombinant vaccine against hepatitis B simultaneously (but at separate sites) with diphtheria/tetanus/pertussis (DTP) and oral polio vaccines were examined. Six hundred and twenty-six children (group I) were given hepatitis B vaccine at 0, 2 and 6 months ...

journal_title：Vaccine

authors： Aristegui J,Muñiz J,Pérez Legorburu A,Imaz M,Arrate JP,Suárez MD,Goiri MD

更新日期：1995-08-01 00:00:00

abstract：:Japanese rabies vaccine, a purified chick embryo cell vaccine manufactured by Kaketsuken (PCEC-K), is normally given subcutaneously; however, this requires a large amount of vaccine, and the pre-exposure vaccination regimen requires 6 months to complete. These factors often hamper appropriate vaccination. Therefore, w...

journal_title：Vaccine

authors： Shiota S,Khawplod P,Ahmed K,Mifune K,Nishizono A

更新日期：2008-11-25 00:00:00

abstract：INTRODUCTION:Clinical trial data management (DM) conducted during outbreaks like that of Ebola virus disease (EVD) in West Africa, 2014-2016, has to adapt to specific, unique circumstances. CTU Bern was asked to set up a safe data capture/management system that could be launched within a few weeks and cover two differe...

journal_title：Vaccine

authors： Hossmann S,Haynes AG,Spoerri A,Diatta ID,Aboubacar B,Egger M,Rintelen F,Trelle S

更新日期：2019-11-15 00:00:00

abstract：:ErbB-2 is associated with several solid tumours of which breast cancer is the commonest cancer in women worldwide. Though anti-ErbB-2 antibody appears to play a significant role in prevention and therapy, naturally occurring anti-ErbB-2 antibody associated with the cleaved ectodomain of overexpressed ErbB-2 self antig...

journal_title：Vaccine

authors： Mukhopadhyay A,Dyring C,Stott DI

更新日期：2014-02-12 00:00:00

abstract：:In Portugal, the 7-valent pneumococcal conjugate vaccine (PCV7) was not introduced in the national immunization plan but was commercially available between 2001 and 2010. We studied serotype distribution and antibiotic susceptibility of Streptococcus pneumoniae carried by children in 2009 and 2010. Vaccination with PC...

journal_title：Vaccine

authors： Nunes S,Félix S,Valente C,Simões AS,Tavares DA,Almeida ST,Paulo AC,Brito-Avô A,de Lencastre H,Sá-Leão R

更新日期：2016-03-29 00:00:00

abstract：:Since 2004, general varicella vaccination has been recommended for all children 11-14 months of age in Germany. The objective of this study was to examine vaccination coverage in children and factors associated with parental acceptance during the first years after recommendation. In a regional surveillance area, cross...

journal_title：Vaccine

authors： Streng A,Seeger K,Grote V,Liese JG

更新日期：2010-08-09 00:00:00

abstract：:T-lymphocyte responses to influenza vaccination were measured in healthy young and older adult volunteers. All participants were vaccinated with the 1995-96 trivalent influenza vaccine. Cytokine and granzyme B levels were measured in peripheral blood mononuclear cells (PBMC) cultures after virus stimulation, prior to ...

journal_title：Vaccine

authors： McElhaney JE,Upshaw CM,Hooton JW,Lechelt KE,Meneilly GS

更新日期：1998-11-01 00:00:00

abstract：:Here, we evaluated the modulation of the immune response induced by Hsp90 of Nicotiana benthamiana (NbHsp90.3) against the Maltose Binding Protein (MBP) as a reporter antigen. Equimolar quantities of recombinant proteins were administered in mice as follows: MBP alone (MBP group), a mixture of MBP and rNbHsp90.3 (MBP+...

journal_title：Vaccine

authors： Corigliano MG,Fenoy I,Sander V,Maglioco A,Goldman A,Clemente M

更新日期：2013-12-02 00:00:00

abstract：:A plasmid DNA vaccine encoding the circumsporozoite protein of malaria (pCSP) induces protective immunity in adult mice but persistent tolerance when administered to neonates. In an effort to improve antigen presenting cell (APC) function in newborns, we co-administered pCSP with a plasmid encoding granulocyte-macroph...

journal_title：Vaccine

authors： Ishii KJ,Weiss WR,Klinman DM

更新日期：1999-11-12 00:00:00

abstract：:Two shots of inactivated Japanese encephalitis (JE) vaccine were given to children, 139 with underlying diseases and 42 healthy, and their antibody responses were studied by the neutralization test. Before vaccination, most of the vaccinees did not have antibody against JE virus. One month after the second vaccination...

journal_title：Vaccine

authors： Yamada A,Imanishi J,Juang RF,Fukunaga T,Okuno Y,Tadano M,Fukai K,Baba K,Yabuuchi H

更新日期：1986-03-01 00:00:00

abstract：:In the present study we evaluated Canavalia brasiliensis (ConBr), Pisum arvense (PAA) and Artocarpus integrifolia (KM+) lectins as immunostimulatory molecules in vaccination against Leishmania amazonensis infection. Although they induced IFN-gamma production, the combination of the lectins with SLA antigen did not lea...

journal_title：Vaccine

authors： Teixeira CR,Cavassani KA,Gomes RB,Teixeira MJ,Roque-Barreira MC,Cavada BS,da Silva JS,Barral A,Barral-Netto M

更新日期：2006-04-05 00:00:00

abstract：:A newly developed human diploid cell rabies vaccine (Lyssavac-HDC), produced without added serum albumin and with an effort to remove the virus-inactivating beta-propriolactone prior to addition of the gelatin, L-cysteine and potassium phosphate stabilizer, was tested for safety immunogenicity, adverse reactions and e...

journal_title：Vaccine

authors： Wilde H,Glueck R,Khawplod P,Cryz SJ,Tantawichien T,Thipkong P,Chomchey P,Prakongsri S,Benjavongkulchai M,Sumboonanondha A

更新日期：1995-04-01 00:00:00

abstract：:The recent spread of Zika virus (ZIKV) in the Americas and the Pacific has reached alarming levels in more than 60 countries. However, relatively little is known about the disease on a virological and epidemiological level and its consequences for humans. Accordingly, a large demand for in vitro derived Brazilian ZIKV...

journal_title：Vaccine

authors： Nikolay A,Castilho LR,Reichl U,Genzel Y

更新日期：2018-05-24 00:00:00

abstract：:Understanding the requirements for protection against pneumococcal carriage and pneumonia will greatly benefit efforts in controlling these diseases. Several antigens, in addition to the polysaccharide capsule, have been implicated in both the virulence and protective immunity against Streptococcus pneumoniae; one of ...

journal_title：Vaccine

authors： Singh R,Singh S,Briles DE,Taub DD,Hollingshead SK,Lillard JW Jr

更新日期：2012-02-01 00:00:00

abstract：:IDU exposure remains a primary driver of the Russian HIV epidemic, and recent incidence data provide little evidence that this epidemic is slowing. While there are multiple important challenges that need to be further explored before starting vaccine trials, most importantly access to evidence-based drug treatment ser...

journal_title：Vaccine

authors： Beyrer C,Baral S,Shaboltas A,Dukhovlinova E,Masharsky A,Verevochkin S,Latkin C,Heimer R,Hoffman I,Kozlov A

更新日期：2007-10-10 00:00:00

abstract：BACKGROUND:In January 2015, Tajikistan introduced the monovalent rotavirus vaccine into the national immunization program. Our objective was to estimate pre-vaccine burden of rotavirus-associated hospitalizations in children <5 years of age in Tajikistan. METHODS:During January 2013-December 2014, active surveillance ...

journal_title：Vaccine

authors： Nazurdinov AB,Azizov ZA,Tishkova F,Turkov SM,Daniels DS,Leshem E

更新日期：2018-12-14 00:00:00

abstract：:Polymeric nanoparticles (NPs) of poly (lactic-co-glycolic) acid (PLGA) possess adjuvant properties. To date, there are few studies exploring their application as antigen carriers for vaccination of fish. This study presents a preclinical assessment of the early innate and adaptive immune responses in Atlantic salmon f...

journal_title：Vaccine

authors： Fredriksen BN,Sævareid K,McAuley L,Lane ME,Bøgwald J,Dalmo RA

更新日期：2011-10-26 00:00:00

abstract：BACKGROUND:Inactivated quadrivalent influenza vaccine (IIV4) containing two influenza A strains and one strain from each B lineage (Yamagata and Victoria) may offer broader protection against seasonal influenza than inactivated trivalent influenza vaccine (IIV3), containing a single B strain. This study examined the sa...

journal_title：Vaccine

authors： Cadorna-Carlos JB,Nolan T,Borja-Tabora CF,Santos J,Montalban MC,de Looze FJ,Eizenberg P,Hall S,Dupuy M,Hutagalung Y,Pépin S,Saville M

更新日期：2015-05-15 00:00:00

abstract：:The ability of a genetically detoxified mutant of heat labile enterotoxin (LTK63) to act as a mucosal adjuvant following intranasal immunization with recombinant gD2 has previously been reported in mice [Ugozzoli M, O'Hagan DT, Ott GS. Intranasal immunization of mice with herpes simplex virus type 2 recombinant gD2: t...

journal_title：Vaccine

authors： O'Hagan D,Goldbeck C,Ugozzoli M,Ott G,Burke RL

更新日期：1999-05-04 00:00:00

abstract：:Two compound Chinese herbal medicinal ingredients (cCHMIs) were prepared, respectively, with epimedium polysaccharide plus propolis flavone (cCHMIs 1) and astragalus polysaccharide plus ginsenoside (cCHMIs 2). In animal immune experiment, Newcastle disease vaccine was mixed, respectively, with two cCHMIs and IL-2 to v...

journal_title：Vaccine

authors： Wang D,Li X,Xu L,Hu Y,Zhang B,Liu J

更新日期：2006-11-30 00:00:00

abstract：:The 2-1-1 rabies postexposure treatment schedule is an abbreviated regimen in which a tissue culture rabies vaccine is administered intramuscularly at two sites on day 0, and at one site on days 7 and 21. Compared to the standard five-dose intramuscular regimen, the 2-1-1 schedule reduces the number of clinic visits f...

journal_title：Vaccine

authors： Chutivongse S,Wilde H,Fishbein DB,Baer GM,Hemachudha T

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Concern arose in 2010 that reactogenicity, particularly febrile seizures, to influenza A/H1N1-containing 2010-2011 trivalent seasonal inactivated influenza vaccine (TIV) could occur in young children who had been previously immunized and/or infected with the pandemic strain. We conducted a pre-season study o...

journal_title：Vaccine

authors： Langley JM,Scheifele DW,Quach C,Vanderkooi OG,Ward B,McNeil S,Dobson S,Kellner JD,Kuhn S,Kollman T,MacKinnon-Cameron D,Smith B,Li Y,Halperin SA

更新日期：2012-05-14 00:00:00

abstract：:To provide a safer live challenge strain for use in clinical vaccine trials, a double drug sensitive strain of Leishmania major was derived using advances in gene targeting technology by stably introducing into the chromosome a modified HSV-1 thymidine kinase gene (tk), conferring increased sensitivity to ganciclovir ...

journal_title：Vaccine

authors： Davoudi N,Tate CA,Warburton C,Murray A,Mahboudi F,McMaster WR

更新日期：2005-01-19 00:00:00

abstract：INTRODUCTION:In recent years, vaccine preventable diseases such as measles and pertussis have been re-emerging in Western countries, maybe because of decreasing participation in childhood vaccination programs in some countries. There is clear evidence for vaccine efficacy and the risk of adverse effects is low. This ne...

journal_title：Vaccine

authors： Óskarsson Ý,Guðnason Þ,Jónsdóttir GA,Kristinsson KG,Briem H,Haraldsson Á

更新日期：2015-12-16 00:00:00

abstract：:The aim of this work was to evaluate the microencapsulation by spray-drying of inactivated Vibrio cholerae, using methacrylic copolymers Eudragit® L30D-55 and FS30D. The microparticles obtained presented a particle size around 3.0 μm. The preparation temperature affected the morphology and the antigenicity of micropar...

journal_title：Vaccine

authors： Año G,Esquisabel A,Pastor M,Talavera A,Cedré B,Fernández S,Sifontes S,Aranguren Y,Falero G,García L,Solís RL,Pedraz JL

更新日期：2011-08-05 00:00:00

abstract：:The Global Meningococcal Initiative (GMI) is composed of an international group of scientists, clinicians and public health officials with expertise in meningococcal immunology, epidemiology and prevention. The primary goal of the GMI is the promotion of the global prevention of invasive meningococcal disease through ...

journal_title：Vaccine

authors： Harrison LH,Pelton SI,Wilder-Smith A,Holst J,Safadi MA,Vazquez JA,Taha MK,LaForce FM,von Gottberg A,Borrow R,Plotkin SA

更新日期：2011-04-18 00:00:00