The feasibility of HIV vaccine efficacy trials among Russian injection drug users.

Abstract:

:IDU exposure remains a primary driver of the Russian HIV epidemic, and recent incidence data provide little evidence that this epidemic is slowing. While there are multiple important challenges that need to be further explored before starting vaccine trials, most importantly access to evidence-based drug treatment services for trial participants, the current context of high HIV incidence and low genetic diversity of HIV strains, suggests the need for intensified prevention strategies and supports the feasibility of mounting efficacy trials of HIV vaccines among IDUs in the Russian Federation.

journal_name

Vaccine

journal_title

Vaccine

authors

Beyrer C,Baral S,Shaboltas A,Dukhovlinova E,Masharsky A,Verevochkin S,Latkin C,Heimer R,Hoffman I,Kozlov A

doi

10.1016/j.vaccine.2007.07.028

subject

Has Abstract

pub_date

2007-10-10 00:00:00

pages

7014-6

issue

41

eissn

0264-410X

issn

1873-2518

pii

S0264-410X(07)00834-1

journal_volume

25

pub_type

杂志文章

相关文献

VACCINE文献大全
  • A combination of Flt3 ligand cDNA and CpG ODN as nasal adjuvant elicits NALT dendritic cells for prolonged mucosal immunity.

    abstract::We explore cellular and molecular mechanisms of nasal adjuvant of a combination of a plasmid encoding the Flt3 ligand cDNA (pFL) and CpG oligodeoxynucleotides (CpG ODN). The double DNA adjuvant given with OVA maintained prolonged OVA-specific secretory IgA (S-IgA) Ab responses in external secretions for more than 25 w...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2008.06.091

    authors: Fukuiwa T,Sekine S,Kobayashi R,Suzuki H,Kataoka K,Gilbert RS,Kurono Y,Boyaka PN,Krieg AM,McGhee JR,Fujihashi K

    更新日期:2008-09-02 00:00:00

  • Human papillomavirus vaccination and Pap testing profile in Manitoba, Canada.

    abstract:BACKGROUND:Females who receive the human papillomavirus (HPV) vaccine may believe they are protected from developing cervical cancer and no longer require screening. Concern has also been expressed that vaccinated females are those that would be screened regularly. This study assesses the Pap testing behavior of vaccin...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2013.10.082

    authors: Kliewer EV,Mahmud SM,Demers AA,Lambert P

    更新日期:2013-12-17 00:00:00

  • The suitability of yellow fever and Japanese encephalitis vaccines for immunization against West Nile virus.

    abstract::Seven volunteers involved in flavivirus studies have been immunized with commercial Japanese encephalitis and yellow fever vaccines JE-VAX and YF-VAX. Strong homologous and cross-reactive with West Nile virus (WNV) antibody responses with titers 1:1600 to 1:51200 were found in all donors. All donors developed high lev...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2005.04.036

    authors: Yamshchikov G,Borisevich V,Kwok CW,Nistler R,Kohlmeier J,Seregin A,Chaporgina E,Benedict S,Yamshchikov V

    更新日期:2005-09-15 00:00:00

  • Prothymosin alpha enhances protective immune responses induced by oral DNA vaccination against pseudorabies delivered by Salmonella choleraesuis.

    abstract::Previously, we showed that vaccination with the glycoprotein D (gD) gene of pseudorabies virus (PrV) delivered by Escherichia coli induced protective immune responses. In this study, we report that oral DNA vaccination with attenuated Salmonella choleraesuis carrying the PrV gD gene conferred protective immunity in mi...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/s0264-410x(01)00130-x

    authors: Shiau AL,Chen YL,Liao CY,Huang YS,Wu CL

    更新日期:2001-07-16 00:00:00

  • Immunogenicity and safety of human papillomavirus vaccine coadministered with other vaccines in individuals aged 9-25 years: A systematic review and meta-analysis.

    abstract:INTRODUCTION:Adolescents and young adults are at a high risk of developing human papillomavirus (HPV) infections, which can be prevented with the use of vaccines. Moreover, a combined immunization strategy for administration of HPV vaccines with other routine vaccines may lead to better compliance. We aim to comprehens...

    journal_title:Vaccine

    pub_type: 杂志文章,评审

    doi:10.1016/j.vaccine.2019.10.092

    authors: Li Y,Zhu P,Wu M,Zhang Y,Li L

    更新日期:2020-01-10 00:00:00

  • Placebo use in vaccine trials: recommendations of a WHO expert panel.

    abstract::Vaccines are among the most cost-effective interventions against infectious diseases. Many candidate vaccines targeting neglected diseases in low- and middle-income countries are now progressing to large-scale clinical testing. However, controversy surrounds the appropriate design of vaccine trials and, in particular,...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2014.04.022

    authors: Rid A,Saxena A,Baqui AH,Bhan A,Bines J,Bouesseau MC,Caplan A,Colgrove J,Dhai A,Gomez-Diaz R,Green SK,Kang G,Lagos R,Loh P,London AJ,Mulholland K,Neels P,Pitisuttithum P,Sarr SC,Selgelid M,Sheehan M,Smith PG

    更新日期:2014-08-20 00:00:00

  • Immune response to a booster dose of enhanced potency inactivated polio vaccine administered in association with HBV vaccine in adolescents.

    abstract::The immunogenicity and reactogenicity of a booster dose of enhanced potency inactivated polio vaccine (EIPV) were evaluated in 492 healthy 12 year old adolescents. The booster was administered at the same time as the HBV vaccine compulsory in Italy at this age. Blood samples and questionnaires on reactogenicity were c...

    journal_title:Vaccine

    pub_type: 临床试验,杂志文章

    doi:10.1016/0264-410x(95)00209-j

    authors: Pregliasco F,Grilli G,Andreassi A,D'Addezio E,Vacca F,Squarcione S,Biasio LR,Profeta M

    更新日期:1996-03-01 00:00:00

  • Intravaginal immunization in sheep using a bioadhesive microsphere antigen delivery system.

    abstract::An enzymatically cleaved glycoprotein fragment (amino acids 28-328: 40 kDa) from influenza virus haemagglutinin (TOPS) was used to assess an intravaginal antigen delivery system, comprising lysophosphatidylcholine (LPC) and degradable starch microspheres (DSM). Three groups of three sheep received intravaginal immuniz...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/0264-410x(93)90313-m

    authors: O'Hagan DT,Rafferty D,Wharton S,Illum L

    更新日期:1993-01-01 00:00:00

  • Pertussis vaccination in pregnancy: State of the art.

    abstract::Pertussis vaccination in pregnancy has been introduced by several national advisory bodies, mostly in industrialized countries, as a means to protect young infants from disease by high titers of maternal antibodies. Most recommendations derive from epidemiological needs, but many knowledge gaps remained after implemen...

    journal_title:Vaccine

    pub_type: 杂志文章,评审

    doi:10.1016/j.vaccine.2017.03.061

    authors: Leuridan E

    更新日期:2017-08-16 00:00:00

  • Similar long-term vaccine efficacy of two versus three doses of HBV vaccine in early life.

    abstract::WHO currently recommends three vaccinations against hepatitis B to provide optimal protection against infection and carriage. However, immunological theory and mathematical modelling suggest that similar protection could be induced with two doses, and trials among adolescents and adults have shown comparable rates for...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2006.10.023

    authors: van der Sande MA,Mendy M,Waight P,Doherty C,McConkey SJ,Hall AJ,Whittle HC

    更新日期:2007-02-09 00:00:00

  • Enhancement of the protective effect of inactivated influenza virus vaccine by cytokines.

    abstract::The authors examined whether or not cytokines in conjunction with inactivated influenza virus vaccine enhance protection from influenza virus infection in mice. Mice were infected with influenza virus A/PR/8/34 (PR/8) at 10 LD50 by nebulizer after intranasal administration of the cytokine and the vaccine. The survival...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/0264-410x(92)90158-g

    authors: Cao M,Sasaki O,Yamada A,Imanishi J

    更新日期:1992-01-01 00:00:00

  • Improvement of a recombinant avian avulavirus serotype 10 vectored vaccine by the addition of untranslated regions.

    abstract:BACKGROUND:We have previously developed a recombinant avian avulavirus serotype 10 (rAAvV-10/HA) expressing the hemagglutinin (HA) gene of a highly pathogenic avian influenza virus (HPAIV) as an emergency vaccine for poultry. rAAvV-10/HA can overcome the activity of the anti-AAvV-1 (Newcastle disease virus) antibody ac...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2019.10.098

    authors: Tsunekuni R,Tanikawa T,Nakaya T,Saito T

    更新日期:2020-01-22 00:00:00

  • Early immune responses in Atlantic salmon (Salmo salar L.) after immunization with PLGA nanoparticles loaded with a model antigen and β-glucan.

    abstract::Polymeric nanoparticles (NPs) of poly (lactic-co-glycolic) acid (PLGA) possess adjuvant properties. To date, there are few studies exploring their application as antigen carriers for vaccination of fish. This study presents a preclinical assessment of the early innate and adaptive immune responses in Atlantic salmon f...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2011.08.087

    authors: Fredriksen BN,Sævareid K,McAuley L,Lane ME,Bøgwald J,Dalmo RA

    更新日期:2011-10-26 00:00:00

  • Phase I/II studies to evaluate safety and immunogenicity of a recombinant gp350 Epstein-Barr virus vaccine in healthy adults.

    abstract::Two double-blind randomised controlled studies (phase I and I/II) were performed to assess for the first time the safety and immunogenicity of a recombinant subunit gp350 Epstein-Barr virus (EBV) vaccine in 148 healthy adult volunteers. All candidate vaccine formulations had a good safety profile and were well tolerat...

    journal_title:Vaccine

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.vaccine.2007.04.008

    authors: Moutschen M,Léonard P,Sokal EM,Smets F,Haumont M,Mazzu P,Bollen A,Denamur F,Peeters P,Dubin G,Denis M

    更新日期:2007-06-11 00:00:00

  • Factors affecting immunization rate in a cohort of elderly veterans: a retrospective pilot study of influenza vaccine compliance.

    abstract::A survey of aged veterans greater than or equal to 85 years old was undertaken to determine their vaccination behaviour prior to mounting a local education campaign on influenza vaccine. A questionnaire inquiring into circumstances which may have influenced their decision to be immunized against influenza was mailed t...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/0264-410x(89)90163-1

    authors: Ganguly R,Cameron D

    更新日期:1989-10-01 00:00:00

  • Intranasal immunization with SIV virus-like particles (VLPs) elicits systemic and mucosal immunity.

    abstract::By using a baculovirus expression system, we have successfully produced simian immunodeficiency virus (SIV)-like particles (VLPs) with high levels of biologically active SIV envelope (Env) incorporated on their surfaces. To study whether SIV VLPs represent effective mucosal immunogens, we immunized groups of mice with...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/s0264-410x(02)00160-3

    authors: Yao Q,Vuong V,Li M,Compans RW

    更新日期:2002-06-07 00:00:00

  • Intranasal vaccination with ebola virus GP amino acids 258-601 protects mice against lethal challenge.

    abstract::Ebola virus (EBOV) disease (EVD) leads to lethal hemorrhagic fever with a case fatality rate as high as 90%, thus posing a serious global public health concern. However, while several vaccines based on the EBOV glycoprotein have been confirmed to be effective in animal experiments, no licensed vaccines or effective tr...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2018.09.003

    authors: Su QD,He SH,Yi Y,Qiu F,Lu XX,Jia ZY,Meng QL,Fan XT,Tian RG,Audet J,Qiu XG,Bi SL

    更新日期:2018-10-01 00:00:00

  • Formulation of HIV-1 Tat and p24 antigens by PLA nanoparticles or MF59 impacts the breadth, but not the magnitude, of serum and faecal antibody responses in rabbits.

    abstract::Biodegradable nanoparticles coated with proteins represent a promising method for in vivo delivery of vaccines. Here we used a rabbit model to compare quantitatively and qualitatively the antibody responses induced by poly(D,L-lactide) nanoparticles (PLA) and by emulsion adjuvant MF59 using three HIV-1 antigens: p24ga...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2007.08.060

    authors: Guillon C,Mayol K,Terrat C,Compagnon C,Primard C,Charles MH,Delair T,Munier S,Verrier B

    更新日期:2007-10-23 00:00:00

  • Human papillomavirus vaccines: WHO position paper, October 2014-Recommendations.

    abstract::This article presents the World Health Organization's (WHO) recommendations for the use of vaccines against diseases caused by human papillomaviruses (HPV) from the WHO position paper on Human papillomavirus vaccines: WHO position paper - October 2014, recently published in the Weekly Epidemiological Record [1]. This ...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2014.12.002

    authors:

    更新日期:2015-08-26 00:00:00

  • Clinical experience with inactivated, virosomal influenza vaccine.

    abstract::Current available influenza vaccines are safe and effective in preventing influenza. Nevertheless, there is a need for influenza vaccines with improved efficacy in the elderly. This need is underscored by both the observation that influenza has a major clinical and economic impact in the elderly and the fact that curr...

    journal_title:Vaccine

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/j.vaccine.2005.04.020

    authors: de Bruijn IA,Nauta J,Cramer WC,Gerez L,Palache AM

    更新日期:2005-07-08 00:00:00

  • Immunogenicity and protective efficacy of an inactivated cell culture-derived Seneca Valley virus vaccine in pigs.

    abstract::Seneca Valley virus (SVV) infection in pigs is associated with porcine idiopathic vesicular disease (PIVD). Outbreaks of SVV infection in pig herds have been reported in several Asia and Americas countries. Recently, a series of outbreaks of SVV infection occurred in China, Canada, Thailand and the United States. Howe...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2017.12.055

    authors: Yang F,Zhu Z,Cao W,Liu H,Zhang K,Tian H,Liu X,Zheng H

    更新日期:2018-02-01 00:00:00

  • Multi-peptide vaccines vialed as peptide mixtures can be stable reagents for use in peptide-based immune therapies.

    abstract::To date, most peptide-based vaccines evaluated for the treatment of cancer have consisted of one or few peptides. However, as a greater number of peptide antigens become available for use in experimental therapies, it is important to establish the feasibility of combining multi-peptide reagents as individual peptide m...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2009.01.018

    authors: Chianese-Bullock KA,Lewis ST,Sherman NE,Shannon JD,Slingluff CL Jr

    更新日期:2009-03-10 00:00:00

  • A qualitative analysis of the impact of healthcare personnel influenza vaccination requirements in California.

    abstract:OBJECTIVE:Using qualitative methods, we explored the implementation of California's 2007 influenza immunization requirements of hospital-based health care personnel (HCP). METHODS:We conducted nine case studies of California hospitals with different HCP vaccination rates and policies. Case studies consisted of intervi...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2013.06.077

    authors: Khodyakov D,Uscher-Pines L,Lorick SA,Lindley MC,Shier V,Harris K

    更新日期:2014-05-23 00:00:00

  • The immunogenicity-enhancing effect of emulsion vaccine adjuvants is independent of the dispersion type and antigen release rate--a revisit of the role of the hydrophile-lipophile balance (HLB) value.

    abstract::Effective antigen delivery is one of the most important issues in vaccine development. It has been suggested that adjuvant action results from a depot effect by prolonging the duration of the interaction between antigen and cells, and thus is related to the antigen-releasing properties of emulsion adjuvants. The objec...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2004.09.007

    authors: Yang YW,Wei AC,Shen SS

    更新日期:2005-04-08 00:00:00

  • Development and validation of a quantitative competitive ELISA for potency testing of equine anti rabies sera with other potential use.

    abstract::In case of a bite by a rabies infected animal, the World Health Organisation recommends a prophylactic treatment including the administration of Human Rabies Immunoglobulins (HRIGs) or highly purified F(ab')2 fragments produced from Equine Rabies Immunoglobulin (F(ab')2 - ERIGs). According to international regulation,...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2016.04.086

    authors: Korimbocus J,Dehay N,Tordo N,Cano F,Morgeaux S

    更新日期:2016-06-14 00:00:00

  • Validity of self-reported pneumococcal vaccination status in the elderly in Spain.

    abstract::The objective of this study was to evaluate the validity of information reported by the elderly on 23-valent pneumococcal polysaccharide vaccine (23vPPV) vaccination status. A cross-sectional, observational study was carried out in patients aged >or=65 years admitted to five Spanish hospitals. Data on 23vPPV vaccinati...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2009.05.057

    authors: Bayas JM,Izquierdo C,Ruiz L,Sintes X,Sousa D,Celorrio JM,Varona W,Carratalà J,Nebot M,Batalla J,Sugrañes S,Manzur A,Terren A,García C,Clemente E,Rivera S,Justo I,Arévalo A,Salleras L,Domínguez A

    更新日期:2009-07-23 00:00:00

  • Immune responses in mice induced by prime-boost schemes of the Plasmodium falciparum apical membrane antigen 1 (PfAMA1)-based DNA, protein and recombinant modified vaccinia Ankara vaccines.

    abstract::The apical membrane antigen 1 (AMA1) of malaria parasites is a leading vaccine candidate. Its expression in merozoites and sporozoites and its importance for erythrocyte and hepatocyte invasion underline the significance of both humoral and cellular immunities against this antigen in malaria protection. We have genera...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2006.05.099

    authors: Miao J,Li X,Liu Z,Xue C,Bujard H,Cui L

    更新日期:2006-09-11 00:00:00

  • Safety of influenza vaccination during pregnancy: a review of subsequent maternal obstetric events and findings from two recent cohort studies.

    abstract::Pregnant women and their infants are vulnerable to severe disease and secondary complications from influenza infection. For this reason, annual influenza vaccination is recommended for all pregnant women in the United States. Women frequently cite concerns about vaccine safety as a barrier to vaccination. This review ...

    journal_title:Vaccine

    pub_type: 杂志文章,评审

    doi:10.1016/j.vaccine.2014.04.021

    authors: Naleway AL,Irving SA,Henninger ML,Li DK,Shifflett P,Ball S,Williams JL,Cragan J,Gee J,Thompson MG,Vaccine Safety Datalink and Pregnancy and Influenza Project.

    更新日期:2014-05-30 00:00:00

  • Determinants of susceptibility to challenge and the antibody response of adult volunteers given experimental respiratory syncytial virus vaccines.

    abstract::The virulence and immunogenicity of a wild-type respiratory syncytial (RS) virus together with four temperature sensitive (ts) mutants derived from this isolate were tested by intranasal inoculation into adult volunteers. Resistance to challenge correlated with neutralizing antibody titres in nasal secretions and to a...

    journal_title:Vaccine

    pub_type: 临床试验,杂志文章

    doi:10.1016/0264-410x(90)90051-m

    authors: Watt PJ,Robinson BS,Pringle CR,Tyrrell DA

    更新日期:1990-06-01 00:00:00

  • Core pertussis transmission groups in England and Wales: A tale of two eras.

    abstract::The recent resurgence of pertussis in England and Wales has been marked by infant deaths and rising cases in teens and adults. To understand which age cohorts are most responsible for these trends, we employed three separate statistical methods to analyze high-resolution pertussis reports from 1982 to 2012. The fine-g...

    journal_title:Vaccine

    pub_type: 杂志文章

    doi:10.1016/j.vaccine.2018.01.046

    authors: Bento AI,Riolo MA,Choi YH,King AA,Rohani P

    更新日期:2018-02-21 00:00:00