Molecular cloning, gene localization, and structure of human cyclin B3.

abstract：:Cilia are microtubule-based organelles that are present on the surfaces of almost all vertebrate cells. Most cilia function as sensory or molecular transport structures. Malfunctions of cilia have been implicated in several diseases of human development. The assembly of cilia is initiated by the centriole (or basal bo...

journal_title：Biochemical and biophysical research communications

authors： Nagai Y,Asaoka Y,Namae M,Saito K,Momose H,Mitani H,Furutani-Seiki M,Katada T,Nishina H

更新日期：2010-06-11 00:00:00

abstract：:Streptococcus mutans, a member of the viridans streptococci, is the etiologic agent of dental caries and is also a causative agent of subacute infective endocarditis. The generation of proteolytic molecules, such as plasmin, may be important in the pathogenesis of endocarditis caused by S. mutans. In this study, we de...

journal_title：Biochemical and biophysical research communications

authors： Jones MN,Holt RG

更新日期：2004-09-10 00:00:00

abstract：:To examine whether protein kinase C (PKC) plays a role in mediating growth inhibitory effects of hexamethylene bisacetamide (HMBA) we compared a control H29 colon cancer cell line to a derivative, HT29-PKC7, that overexpresses high levels of PKC beta 1. We found that although HMBA markedly inhibited the growth of the ...

journal_title：Biochemical and biophysical research communications

authors： Choi PM,Weinstein IB

更新日期：1991-12-16 00:00:00

abstract：:The molecular conformations of Leu5- and Met5-enkephalins in aqueous and DMSO solutions were investigated by FT-IR and laser Raman spectroscopic methods. The amide I, II, and III regions in the FT-IR spectra of Leu5- and Met5-enkephalins in aqueous solution were analyzed by performing Fourier self-deconvolution of the...

journal_title：Biochemical and biophysical research communications

authors： Renugopalakrishnan V,Rapaka RS,Collette TW,Carreira LA,Bhatnagar RS

更新日期：1985-02-15 00:00:00

abstract：:Three new analogues of trypsin inhibitor CMTI-III were synthesized by the solid-phase method: [Lys5]-CMTI-III, [Orn5]CMTI-III and [Dab5]CMTI-III. Only one analogue with L-lysine residue in position P1 showed inhibitory activity of the same order of magnitude as did wild CMTI-III. Two remaining analogues were completel...

journal_title：Biochemical and biophysical research communications

authors： Jaśkiewicz A,Lesner A,Rózycki J,Rodziewicz S,Rolka K,Ragnarsson U,Kupryszewski G

更新日期：1997-11-26 00:00:00

abstract：:We have recorded multi-frequency EPR spectra of 63Cu- and 65Cu-labeled, water-soluble CuA-protein from the cytochrome ba3 of T. thermophilus. The spectrum taken at the highest frequency (34.03 GHz) shows no hyperfine structure and is nominally axial with apparent gz approximately 2.18 and gxy approximately 2.00. The s...

journal_title：Biochemical and biophysical research communications

authors： Fee JA,Sanders D,Slutter CE,Doan PE,Aasa R,Karpefors M,Vänngård T

更新日期：1995-07-06 00:00:00

abstract：:E3b1, a binding partner of Eps8, plays a critical role in receptor tyrosine kinase (RTK)-mediated Rac activation by facilitating the interaction of Eps8 with Sos-1 and the consequent activation of the Rac-specific guanine nucleotide exchange factor activity of Sos-1. Here we present evidence that E3b1 levels are regul...

journal_title：Biochemical and biophysical research communications

authors： Chi S,Chang S,Park D

更新日期：2004-06-25 00:00:00

abstract：:Newly translated proteins must undergo proper folding to ensure their function. To enter a low energy state, misfolded proteins form aggregates, which are associated with many degenerative diseases, such as Huntington's disease and chronic kidney disease (CKD). Recent studies have shown the use of low molecular weight...

journal_title：Biochemical and biophysical research communications

authors： Upagupta C,Carlisle RE,Dickhout JG

更新日期：2017-04-22 00:00:00

abstract：:Plasma high (HDL) and low (LDL) density lipoproteins were isolated from rats fed a diet supplemented with either fish (menhaden) oil or hydrogenated coconut oil (control). Fluorescence polarization and electron spin resonance of labelled fatty acid probe molecules incorporated into the outer amphiphilic monolayer of H...

journal_title：Biochemical and biophysical research communications

authors： Belcher D,Stillwell W,Langsford CA,Wassall SR

更新日期：1988-02-15 00:00:00

abstract：:We have demonstrated that oral charcoal therapy is as effective as therapeutic phlebotomy in reducing porphyrinemia in porphyria cutanea tarda. The effects of immediate and sustained reduction of porphyrinemia on the catalytic properties of partially purified (approximately 200-fold) preparations of red cell uroporphy...

journal_title：Biochemical and biophysical research communications

authors： Mukerji SK,Pimstone NR

更新日期：1988-07-15 00:00:00

abstract：:Selected purinoceptor modulators were previously shown to prevent glutamate-evoked cytotoxicity in cerebellar granule neurons. In the same cellular system, we now identify and characterize the presence of P2 receptors. The binding of [3H]ATP to membranes of cerebellar granule neurons grows monotonically as a function ...

journal_title：Biochemical and biophysical research communications

authors： Merlo D,Volonté C

更新日期：1996-08-23 00:00:00

abstract：:Glycated insulin was evaluated in plasma and biological tissues of diabetic animal models by immunocytochemistry (ICC) and a novel radioimmunoassay. Glycated insulin circulated at 0.10 +/- 0.04 ng/ml and 2.20 +/- 0.14 ng/ml in lean and diabetic obese (ob/ob) mice, corresponding to 12.5 and 9.8% total plasma insulin, r...

journal_title：Biochemical and biophysical research communications

authors： McKillop AM,Mooney MH,Harriott P,Flatt PR,O'Harte FP

更新日期：2001-08-24 00:00:00

abstract：:With age human collagen demonstrates, amongst other changes, reductions in solubility, elasticity and permeability. Many of these changes have been attributed to non-enzymic glycosylation (glycation)-a spontaneous addition of sugar molecules to any protein with free amino groups. The resulting formation and accumulati...

journal_title：Biochemical and biophysical research communications

authors： Malik NS,Meek KM

更新日期：1994-03-15 00:00:00

abstract：:The transcription of a mouse genomic segment containing four tRNA genes, coding for a tRNA(Ala), a tRNA(Ile), a tRNA(Pro) and a tRNA(Lys), has been studied in a HeLa cell extract, demonstrating that differences among their transcriptional efficiencies are evident using as templates either the natural cluster or an equ...

journal_title：Biochemical and biophysical research communications

authors： Russo T,Oliva A,Duilio A,Ammendola R,Costanzo F,Zannini M,Cimino F

更新日期：1987-12-31 00:00:00

abstract：:While Aspergillus ficuum phytaseA (phyA) was rapidly inactivated by 1,2-cyclohexanedione and phenylglyoxal, both specific modifiers of arginine, phytaseB (phyB) showed a markedly different behavior. First, phyB was totally insensitive to 1,2-cyclohexanedione even in the presence of 0.2 M guanidinium hydrochloride; sec...

journal_title：Biochemical and biophysical research communications

authors： Ullah AH,Sethumadhavan K

更新日期：1998-02-13 00:00:00

abstract：:Infrared spectra of E. coli strain JM103 and transformants which overproduced recombinant proinsulin have been measured as a function of pressure up to 38 kbar. It is the first time that high-pressure infrared spectra of live bacteria have been successfully measured. In ambient conditions, spectra of the host strain J...

journal_title：Biochemical and biophysical research communications

authors： Wong PT,Zahab DM,Narang SA,Sung WL

更新日期：1987-07-15 00:00:00

abstract：:Invaison plasmid antigen D (IpaD) and water-extracted outer-membrane proteins (OMPs) from Shigella flexneri were used to investigate some of the structural relationships of this pathogen's invasions. Extracellular presentation of the three invasion plasmid antigens (Ipa) B, C, and D is required for the S. flexneri inv...

journal_title：Biochemical and biophysical research communications

authors： Marquart ME,Picking WL,Picking WD

更新日期：1995-09-25 00:00:00

abstract：:AMP-activated protein kinase (AMPK) plays a key role in maintaining intracellular and whole-body energy homeostasis. Activation of AMPK has been shown to ameliorate the symptoms of metabolic diseases, such as type 2 diabetes and obesity. Here we show that gambogic acid (GB), a known antitumor agent, activates AMPK by ...

journal_title：Biochemical and biophysical research communications

authors： Zhao B,Shen H,Zhang L,Shen Y

更新日期：2012-07-20 00:00:00

abstract：:Reportedly, in human immunodeficiency virus type 1 (HIV) vectors, insertion of central polypurine tract (cPPT) increased expression of transgenes for a short period. To test this for a stable condition, we constructed a series of vectors carrying a Neo(r) gene as a stable marker driven by a synthetic thymidine kinase ...

journal_title：Biochemical and biophysical research communications

authors： Sakuma R,Kobayashi N,Ae K,Kitamura Y

更新日期：2003-03-14 00:00:00

abstract：:Cholecystokinin (CCK) dose-dependently stimulates enzyme secretion or loss of cell integrity in the exocrine pancreas. Signaling mechanims include tyrosine phosphorylation of p125(FAK) and paxillin. Here, we examine their potential function. Maximum phosphorylation of both proteins was observed after stimulation of fr...

journal_title：Biochemical and biophysical research communications

authors： Leser J,Lührs H,Beil MF,Adler G,Lutz MP

更新日期：1999-01-19 00:00:00

abstract：:Basic fibroblast growth factor (bFGF) and platelet-derived growth factor (PDGF) produced by hepatocellular carcinoma (HCC) cells are responsible for the growth of HCC cells. Accumulating evidence shows that insulin-like growth factor-binding protein-3 (IGFBP-3) suppresses HCC cell proliferation in both IGF-dependent a...

journal_title：Biochemical and biophysical research communications

authors： Ma Y,Han CC,Li Y,Wang Y,Wei W

更新日期：2016-09-16 00:00:00

abstract：:Excessive cellular cholesterol is transported to the liver by a pathway called 'reverse cholesterol transport.' Scavenger receptor class B, type I (SR-BI) mediates cholesterol uptake in the liver. Polyunsaturated fatty acids, known to activate peroxisome proliferator-activated receptor (PPAR), have been reported to in...

journal_title：Biochemical and biophysical research communications

authors： Malerød L,Sporstøl M,Juvet LK,Mousavi A,Gjøen T,Berg T

更新日期：2003-06-06 00:00:00

abstract：:Erythroid band 4.1 enhances the binding of erythroid spectrin to phosphatidylserine vesicles under conditions of ionic strength and at protein concentrations similar to those in the red cell. The extent of enhancement depends on the concentration of band 4.1; at 2 microM 4.1, spectrin binding increases approximately 1...

journal_title：Biochemical and biophysical research communications

authors： Takeshita K,MacDonald RI,MacDonald RC

更新日期：1993-02-26 00:00:00

abstract：:The gene ENOD40 is expressed at an early stage of root nodule organogenesis and has been postulated to play a central regulatory role in the Rhizobium-legume interaction. In vitro translation of soybean ENOD40 mRNA showed that the gene encodes two peptides of 12 and 24aa residues (peptides A and B) that bind to sucros...

journal_title：Biochemical and biophysical research communications

authors： Röhrig H,John M,Schmidt J

更新日期：2004-12-17 00:00:00

abstract：:We demonstrate that the 204 bp intronic gene fragment of C3(1), which has a specific in vitro affinity for the androgen receptor, is able to confer androgen responsiveness to a heterologous promoter. This characteristic is completely destroyed by a single G----T substitution, affecting a 5'-TGTTCT-3' element that clos...

journal_title：Biochemical and biophysical research communications

authors： Claessens F,Celis L,Peeters B,Heyns W,Verhoeven G,Rombauts W

更新日期：1989-10-31 00:00:00

abstract：:The gene located upstream of the nlp gene at min 69 on the chromosome of Escherichia coli was cloned from the plasmid pLC7-42 constructed by Clarke and Carbon. The extract of the strain harboring the plasmid containing this gene showed increased activity of the prenyltransferase. The product of the enzyme reaction was...

journal_title：Biochemical and biophysical research communications

authors： Asai K,Fujisaki S,Nishimura Y,Nishino T,Okada K,Nakagawa T,Kawamukai M,Matsuda H

更新日期：1994-07-15 00:00:00

abstract：:Drug-induced hepatotoxicity causes significant morbidity and mortality and is a major concern in drug development. This is due, in large part, to insufficient knowledge of the mechanism(s) of drug-induced liver injury. In order to address this problem, we have evaluated the modulation of gene expression within the liv...

journal_title：Biochemical and biophysical research communications

authors： Reilly TP,Bourdi M,Brady JN,Pise-Masison CA,Radonovich MF,George JW,Pohl LR

更新日期：2001-03-23 00:00:00

abstract：:We report high resolution images of RecA-double stranded (ds) DNA complexes obtained by atomic force microscopy (AFM). When a carbon nanotube (CNT) tip was used, AFM images visualized the 10-nm pitch of RecA-dsDNA complexes and RecA filaments as three-dimensional surface topography without reconstruction analysis. The...

journal_title：Biochemical and biophysical research communications

authors： Umemura K,Komatsu J,Uchihashi T,Choi N,Ikawa S,Nishinaka T,Shibata T,Nakayama Y,Katsura S,Mizuno A,Tokumoto H,Ishikawa M,Kuroda R

更新日期：2001-02-23 00:00:00

abstract：:It was previously shown that rhodanese, inactivated with hydrogen peroxide, could only be reactivated in the presence of a reductant or the substrate thiosulfate if these reagents were added soon after inactivation and if the oxidant was removed. Here, we report on the facilitated reactivation (75%) of hydrogen peroxi...

journal_title：Biochemical and biophysical research communications

authors： Del Fierro D,Zardeneta G,Mendoza JA

更新日期：2000-08-02 00:00:00

abstract：:The androgen receptor (AR) plays a central role in the development and progression of prostate cancer. AR expression is maintained throughout the progression of prostate cancer and is also associated with an aggressive, castration-resistant (CR) phenotype. Despite the critical roles of AR expression in prostate cancer...

journal_title：Biochemical and biophysical research communications

authors： Lee JW,Kim GY,Kim JH

更新日期：2012-04-06 00:00:00