Intraduodenal and intrajejunal administration of the herbal medicine, dai-kenchu-tou, stimulates small intestinal motility via cholinergic receptors in conscious dogs.

abstract：BACKGROUND AND AIM:Aberrant methylation of specific genes is frequent event in hepatocellular carcinoma (HCC). Our present study aims to explore the methylation levels of acid phosphatase locus 1 (ACP1), bone morphogenetic protein 4 (BMP4), and testis-specific protein, Y-encoded-like 5 (TSPYL5) and their potential clin...

journal_title：Digestive diseases and sciences

authors： Qiu X,Hu B,Huang Y,Deng Y,Wang X,Zheng F

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Diagnosis of eosinophilic esophagitis (EoE) requires quantification of esophageal eosinophilia. AIMS:The aims of this study were to assess inter- and intraobserver reliability for measuring esophageal eosinophil counts and to validate a novel method of determining tissue eosinophil density using digitized h...

journal_title：Digestive diseases and sciences

authors： Dellon ES,Fritchie KJ,Rubinas TC,Woosley JT,Shaheen NJ

更新日期：2010-07-01 00:00:00

abstract：:Data on performance characteristics of flexible sigmoidoscopy (FS) between age groups are limited. This study evaluates screening FS in subjects > or = 75 years of age (elderly) compared with ages 50-74 years (general screening population). Data were collected on patient characteristics, insertion depth, procedural di...

journal_title：Digestive diseases and sciences

authors： Pabby A,Suneja A,Heeren T,Farraye FA

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND AND AIM:Dietary fiber shortens gut transit time, but data on the effects of fiber components (including resistant starch, RS) on intestinal contractility are limited. We have examined RS effects in male Sprague-Dawley rats fed either a high-amylose maize starch (HAMS) or a wholemeal made from high-amylose wh...

journal_title：Digestive diseases and sciences

authors： Patten GS,Kerr CA,Dunne RA,Shaw JM,Bird AR,Regina A,Morell MK,Lockett TJ,Molloy PL,Abeywardena MY,Topping DL,Conlon MA

更新日期：2015-06-01 00:00:00

abstract：:It is known that calcium ion has an important role in the cellular function. For this reason, calcium channel blockers may have a protective action against gastric injury which is induced by various stimuli. In this study, the influence of mibefradil on ethanol-induced gastric injury was investigated in rats. Mibefrad...

journal_title：Digestive diseases and sciences

authors： Bilici D,Banoğlu ZN,Kiziltunç A,Avci B,Ciftçioğlu A,Bilici S

更新日期：2002-04-01 00:00:00

abstract：:To study the efficacy of standard blood tests of liver function (LFTs) and technetium-99m liver scan followed by laparoscopy in the diagnosis of solid malignant tumors of the liver, 100 consecutive patients were evaluated who had these tests because of clinical suspicion of liver neoplasm. Malignant liver tumors were ...

journal_title：Digestive diseases and sciences

authors： Lightdale CJ,Winawer SJ,Kurtz RC,Knapper WH

更新日期：1979-08-01 00:00:00

abstract：:It is known that the muscularis mucosae and mucosa are not pharmacologically homogeneous throughout the rat colon. The aim of this study was to simultaneously characterize all three neurokinin (NK) receptors in the muscularis mucosae and mucosa along the length of the rat colon. Strips of proximal, mid, and distal col...

journal_title：Digestive diseases and sciences

authors： Appleyard CB,Morales M,Percy WH

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Peyer's patches (PPs), which are covered by specialized follicle-associated epithelium (FAE) including M cells, play a central role in immune induction in the gastrointestinal tract. This study is to investigate a new molecule to characterize PPs. METHODS:We generated a monoclonal antibody (mAb 10-15-3-3) t...

journal_title：Digestive diseases and sciences

authors： Tokuhara D,Nochi T,Matsumura A,Mejima M,Takahashi Y,Kurokawa S,Kiyono H,Yuki Y

更新日期：2014-11-01 00:00:00

abstract：BACKGROUND:Numerous experiments have shown that alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) are present in cells of various cancer and can play role in carcinogenesis. In previous investigations we have found elevated levels of alcohol dehydrogenase class III activity in pancreatic cancer cells. It ca...

journal_title：Digestive diseases and sciences

authors： Jelski W,Zalewski B,Szmitkowski M

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Interferon regulatory factor 9 (IRF9) acts as a negative regulator of sirtuin-1 (SIRT1) to participate in many diseases. However, the role of SIRT1 and IRF9 in hyperlipidemia acute pancreatitis associated with kidney injury is unclear. AIMS:To explore the function of SIRT1 and IRF9 in hyperlipidemia acute p...

journal_title：Digestive diseases and sciences

authors： Liu Y,Sun Y,Xue BH,Wang XD,Yu WL

更新日期：2020-05-28 00:00:00

abstract：INTRODUCTION:Crohn's disease (CD) and ulcerative colitis (UC) are associated with considerable direct healthcare costs. There have been few comprehensive analyses of all IBD- and non-IBD comorbidities that determine direct costs in this population. METHODS:We used data from a validated cohort of patients with inflamma...

journal_title：Digestive diseases and sciences

authors： Cai W,Cagan A,He Z,Ananthakrishnan AN

更新日期：2020-05-20 00:00:00

abstract：BACKGROUND AND AIMS:Nonalcoholic fatty liver disease (NAFLD) is the number one cause of liver disease in the United States. The prevalence rates in African Americans (AA), while significantly lower than other ethnic groups with similar known risk factors, have been quoted as high as 24 %. We aim to determine if the pre...

journal_title：Digestive diseases and sciences

authors： Foster T,Anania FA,Li D,Katz R,Budoff M

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:It is not known whether transjugular intrahepatic porto-systemic shunt (TIPS) is safe in patients with advanced liver cirrhosis. The aim of our study was to evaluate the impact of TIPS on transplant-free survival in patients with liver cirrhosis and MELD score ≥15. METHODS:All adult patients who underwent T...

journal_title：Digestive diseases and sciences

authors： Ascha M,Hanouneh M,S Ascha M,Zein NN,Sands M,Lopez R,Hanouneh IA

更新日期：2017-02-01 00:00:00

abstract：:Alterations in smooth muscle responsiveness and neural pathways in adjacent tissue may occur after local myenteric denervation. The in vitro contractile responses of both longitudinal and circular muscle to the mixed muscarinic and nicotinic cholinergic agonist carbachol were determined 15, 30, and 45 days after local...

journal_title：Digestive diseases and sciences

authors： Herman JR,Bass P

更新日期：1990-09-01 00:00:00

abstract：OBJECTIVE:This study focused on unhealed gastrocutaneous fistulas to resolve whether standard drugs that promote healing of gastric ulcers may simultaneously have the same effect on cutaneous wounds, and corticosteroid aggravation, and to demonstrate why peptides such as BPC 157 exhibit a greater healing effect. Theref...

journal_title：Digestive diseases and sciences

authors： Skorjanec S,Dolovski Z,Kocman I,Brcic L,Blagaic Boban A,Batelja L,Coric M,Sever M,Klicek R,Berkopic L,Radic B,Drmic D,Kolenc D,Ilic S,Cesarec V,Tonkic A,Zoricic I,Mise S,Staresinic M,Ivica M,Lovric Bencic M,Anic

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Regenerating islet-derived 3 (Reg3) is abnormally expressed in several human digestive system diseases, including chronic pancreatitis (CP) and pancreatic cancer (PC). AIM:The purpose of this study was to clarify the mechanism of the enhanced expression of Reg3 in inflammation-induced PC. METHODS:C57BL/6 m...

journal_title：Digestive diseases and sciences

authors： Yin G,Du J,Cao H,Liu X,Xu Q,Xiang M

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Sigmoid volvulus is a common condition in elderly patients with elongated colons. Although endoscopic de-torsion is effective as the primary treatment of sigmoid volvulus, elective surgery is recommended because of the high risk of recurrence and high mortality rate. AIM:The aim of this study was to determi...

journal_title：Digestive diseases and sciences

authors： Kusunoki R,Fujishiro H,Miyake T,Suemitsu S,Kataoka M,Fujiwara A,Tsukano K,Kotani S,Yamanouchi S,Aimi M,Tanaka M,Miyaoka Y,Kohge N,Imaoka T,Yuasa K,Kodama K,Ishihara S,Kinoshita Y

更新日期：2020-05-14 00:00:00

abstract：AIM:Although Ebola virus infection (EVI) clinically presents with common, prominent, gastroenterologic manifestations, this subject has not been previously reviewed. This work critically and comprehensively reviews this subject. METHODS:This study is a comprehensive literature review generated by computerized search o...

journal_title：Digestive diseases and sciences

authors： Sharma N,Cappell MS

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Liver stiffness measurement (LSM) by transient elastography is a popular noninvasive test of fibrosis. Traditional LSM cutoffs dichotomize patients and do not clearly indicate the confidence of diagnosis. AIM:We derived and validated probability functions of fibrosis and cirrhosis based on LSM and determine...

journal_title：Digestive diseases and sciences

authors： Wong VW,Lampertico P,de Lédinghen V,Chang PE,Kim SU,Chen Y,Chan HL,Mangia G,Foucher J,Chow WC,Ahn SH,Hou J

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Approximately 10-28 % of patients experience adverse drug reactions related to treatment with thiopurines. The most serious reaction is myelosuppression, typically manifested as leucopenia, which occurs in approximately 2-5 % of patients. Other adverse drug reactions that often accompany thiopurine therapy a...

journal_title：Digestive diseases and sciences

authors： Wroblova K,Kolorz M,Batovsky M,Zboril V,Suchankova J,Bartos M,Ulicny B,Pav I,Bartosova L

更新日期：2012-09-01 00:00:00

abstract：:Many drugs have been used in the treatment of chronic hepatitis B, but with the exception of interferon, none have proved to be effective. Several studies have found that a sustained loss of viral replication occurs in approximately 40% of patients who started with a 16-week course of recombinant interferon alfa-2b gi...

journal_title：Digestive diseases and sciences

authors： Perrillo RP

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:The early diagnosis of pancreas allograft dysfunction is crucial for the management and long-term survival of transplanted pancreases. We investigated whether intercellular adhesion molecular-1 (ICAM-1), Fas, and Fas ligand (FasL) can be used as novel biomarkers of acute pancreaticoduodenal allograft dysfunc...

journal_title：Digestive diseases and sciences

authors： Dong GH,Li XF,Li JZ,Zhang ZD,Hu WM,Luo YH,Li ZD,Tian BL,He MX,Zhu XW

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Previous studies have demonstrated the value of systematic feedback in enhancing endoscopic procedure performance. It remains unknown whether feedback may play a role in modifying physician performance in outpatient practice. This study aimed to assess the impact of systematic feedback on duration o...

journal_title：Digestive diseases and sciences

authors： Harewood GC

更新日期：2011-10-01 00:00:00

abstract：:The effect of smoking on interdigestive gastrointestinal motility is little studied but may play a role in gastrointestinal morbidity. We studied gastroduodenal motility in 10 volunteers (five smokers and five nonsmokers) using a water-perfused pressure catheter. A pH probe was placed in the duodenal bulb. Baseline mo...

journal_title：Digestive diseases and sciences

authors： McDonnell WM,Owyang C

更新日期：1995-12-01 00:00:00

abstract：:In a randomized trial, 75 patients with an endoscopically confirmed and symptomatic duodenal (N = 50) or prepyloric (N = 25) ulcer were allocated to cimetidine treatment (1 g/day) either regularly for four weeks (standard treatment group) or regularly for a minimum of one week and thereafter only until the symptoms we...

journal_title：Digestive diseases and sciences

authors： Gustavsson S,Adami HO,Lööf L,Nyberg A,Nyrén O

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND AND AIM:Although the serum sodium level has been reported to be a prognostic and predictive marker for the therapeutic effects of lung cancer and renal cell carcinoma treated with molecular targeted therapy, the serum sodium level has not been investigated in hepatocellular carcinoma (HCC) patients treated w...

journal_title：Digestive diseases and sciences

authors： Kegasawa T,Sakamori R,Maesaka K,Yamada R,Tahata Y,Urabe A,Kodama T,Hikita H,Imanaka K,Ohkawa K,Hiramatsu N,Oshita M,Yamada Y,Inada M,Yakushijin T,Imai Y,Tatsumi T,Takehara T

更新日期：2020-06-17 00:00:00

abstract：:In a young woman with Takayasu's arteritis, standard roentgenographic studies suggested a diagnosis of Crohn's ileocolitis. Mesenteric angiography was performed and revealed specific abnormalities diagnostic of Crohn's disease, namely, the zoning sign in the cecum with a hypervascular inner layer and a hypovascular ou...

journal_title：Digestive diseases and sciences

authors： Friedman CJ,Tegtmeyer CJ

更新日期：1979-12-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori infection is an established causal factor for non-cardia gastric cancer. H. pylori negative gastric cancer prevalence among US patients is unclear. METHODS:This retrospective cohort study examined H. pylori prevalence among consecutive patients with incident non-cardia gastric adenocarci...

journal_title：Digestive diseases and sciences

authors： Nguyen TH,Mallepally N,Hammad T,Liu Y,Thrift AP,El-Serag HB,Tan MC

更新日期：2020-08-01 00:00:00

abstract：:New studies monitoring ambulatory esophageal pressures during food ingestion often compare results to normal values obtained from supine liquid swallows. We compared distal esophageal peristaltic and lower esophageal sphincter (LES) pressures in 15 normal subjects during six liquid swallows in the upright and supine p...

journal_title：Digestive diseases and sciences

authors： Sears VW Jr,Castell JA,Castell DO

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:One of the problems associated with infliximab (IFX) treatment for Crohn's disease (CD) is loss of response during maintenance therapy. AIMS:The aim of this multicenter, retrospective, cohort study was to determine whether enteral nutrition (EN) added to the IFX therapy regimen is effective for maintaining ...

journal_title：Digestive diseases and sciences

authors： Hirai F,Ishihara H,Yada S,Esaki M,Ohwan T,Nozaki R,Ashizuka S,Inatsu H,Ohi H,Aoyagi K,Mizuta Y,Matsumoto T,Matsui T

更新日期：2013-05-01 00:00:00