Marine nitrogen fixation: what's the fuss?


:Biological nitrogen fixation is a much more important process in the nitrogen cycle of the oceans than previously thought. Further, nitrogen fixation may have an influence on the capacity of the oceans to sequester carbon. A greater diversity of marine nitrogen fixers has also been uncovered but their quantitative significance remains to be determined.


Curr Opin Microbiol


Capone DG




Has Abstract


2001-06-01 00:00:00














  • Single cell genomics: an individual look at microbes.

    abstract::Single cell genomics (SCG) uncovers hereditary information at the most basic level of biological organization. It is emerging as a powerful complement to cultivation-based and microbial community-focused research approaches. SCG has been instrumental in identifying metabolic features, evolutionary histories and inter-...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Stepanauskas R

    更新日期:2012-10-01 00:00:00

  • Genomics of parasitic and symbiotic fungi.

    abstract::Complete and partial genome sequence information is underway in several parasitic and symbiotic fungi that infect humans, other animals and plants. Comparative analyses of these sequences will provide new insights into the genomic plasticity and evolution of parasitism and mutualism in fungi. ...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Tunlid A,Talbot NJ

    更新日期:2002-10-01 00:00:00

  • YidC--an evolutionary conserved device for the assembly of energy-transducing membrane protein complexes.

    abstract::Members of the YidC/Oxa1/Alb3 membrane protein family are multifunctional mediators of membrane protein integration, folding and assembly into large complexes. Their evolutionary conserved and physiologically important role appears to relate to the assembly of major energy-transducing membrane protein complexes. ...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: van der Laan M,Nouwen NP,Driessen AJ

    更新日期:2005-04-01 00:00:00

  • Prospects for new antitubercular drugs.

    abstract::The inexorable rise in cases of tuberculosis worldwide, fuelled by the HIV epidemic, highlights the need for new drugs and particularly those that can shorten the duration of treatment. Clinical trials of existing broad-spectrum agents such as the fluoroquinolone moxifloxacin are proceeding, on the basis of efficacy i...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Duncan K,Barry CE 3rd

    更新日期:2004-10-01 00:00:00

  • Bacterial morphogenesis: learning how cells make cells.

    abstract::Bacteria furnish tractable models for complex biological processes, and morphogenesis is now taking its turn. We can already explain in general terms how such elementary forms as rods and cocci are produced, and the shapes of several individual organisms are coming into focus. In most bacteria shape is maintained by t...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Harold FM

    更新日期:2007-12-01 00:00:00

  • Genome archeology leading to the characterization and classification of transport proteins.

    abstract::In the study of transmembrane transport, molecular phylogeny provides a reliable guide to protein structure, catalytic and noncatalytic transport mechanisms, mode of energy coupling and substrate specificity. It also allows prediction of the evolutionary history of a transporter family, leading to estimations of its a...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章


    authors: Saier MH

    更新日期:1999-10-01 00:00:00

  • Antimicrobial photodynamic inactivation: a bright new technique to kill resistant microbes.

    abstract::Photodynamic therapy (PDT) uses photosensitizers (non-toxic dyes) that are activated by absorption of visible light to form reactive oxygen species (including singlet oxygen) that can oxidize biomolecules and destroy cells. Antimicrobial photodynamic inactivation (aPDI) can treat localized infections. aPDI neither cau...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Hamblin MR

    更新日期:2016-10-01 00:00:00

  • Roles of adaptor proteins in regulation of bacterial proteolysis.

    abstract::Elimination of non-functional or unwanted proteins is critical for cell growth and regulation. In bacteria, ATP-dependent proteases target cytoplasmic proteins for degradation, contributing to both protein quality control and regulation of specific proteins, thus playing roles parallel to that of the proteasome in euk...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Battesti A,Gottesman S

    更新日期:2013-04-01 00:00:00

  • Posttranslational modifications and assembly of septin heteropolymers and higher-order structures.

    abstract::Septins are cytoskeletal elements that contain a highly conserved canonical G domain flanked by more divergent N- and C-termini. Septin monomers form heteropolymers that in turn associate into a variety of higher-order structures. SUMOylation, acetylation and phosphorylation of septins have all been reported; however,...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Hernández-Rodríguez Y,Momany M

    更新日期:2012-12-01 00:00:00

  • Modulation of natural killer cell activity by viruses.

    abstract::Since their discovery, our understanding of NK cells has evolved from branding them marginal innate immunity cells to key players in anti-viral and anti-tumor immunity. Importance of NK cells in control of various viral infections is perhaps best illustrated by the existence of plethora of viral mechanisms aimed to mo...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Lisnić VJ,Krmpotić A,Jonjić S

    更新日期:2010-08-01 00:00:00

  • HIV-host interactions: vital to the virus and key to its inhibition.

    abstract::Much progress has been made in recent years in the investigation of the interplay between HIV-1 and its host cells. Most of these interactions are complex and have not yet been fully unraveled. Nevertheless, current knowledge on the molecular interactions between HIV and host-cell factors has substantially broadened o...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Trkola A

    更新日期:2004-08-01 00:00:00

  • Immunoglobulin-like domains on bacteriophage: weapons of modest damage?

    abstract::Recent work has shown that Immunoglobulin-like (Ig-like) domains occur frequently on the surface of tailed dsDNA bacteriophages. Several of these Ig-like domains are added to bacteriophage structural proteins via programmed ribosomal frameshifts, and their evolutionary patterns suggest that they can be exchanged by ho...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Fraser JS,Maxwell KL,Davidson AR

    更新日期:2007-08-01 00:00:00

  • Advances in understanding the genetic basis of antimalarial drug resistance.

    abstract::The acquisition of drug resistance by Plasmodium falciparum has severely curtailed global efforts to control malaria. Our ability to define resistance has been greatly enhanced by recent advances in Plasmodium genetics and genomics. Sequencing and microarray studies have identified thousands of polymorphisms in the P....

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Ekland EH,Fidock DA

    更新日期:2007-08-01 00:00:00

  • Connections between transcriptional regulation and type III secretion?

    abstract::Type III secretion is a mechanism of protein export in bacteria, by which proteins (termed effectors) are exported from the bacteria to the external environment. One topic that has escaped much attention is the potential link between the secretion of effectors and transcriptional regulation of genes encoding the effec...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Miller VL

    更新日期:2002-04-01 00:00:00

  • Animal models in the analysis of Candida host-pathogen interactions.

    abstract::An increasingly diverse array of clinically relevant animal models of candidiasis have been established that mimic both the immune perturbations of the host and tissue-specific features of candidiasis in humans. Cause-and-effect analysis of Candida host-pathogen interactions using these animal models has made a quantu...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: de Repentigny L

    更新日期:2004-08-01 00:00:00

  • Epigenetic regulation of the bacterial cell cycle.

    abstract::N(6)-methyl-adenines can serve as epigenetic signals for interactions between regulatory DNA sequences and regulatory proteins that control cellular functions, such as the initiation of chromosome replication or the expression of specific genes. Several of these genes encode master regulators of the bacterial cell cyc...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Collier J

    更新日期:2009-12-01 00:00:00

  • Robust peptidoglycan growth by dynamic and variable multi-protein complexes.

    abstract::In Gram-negative bacteria such as Escherichia coli the peptidoglycan sacculus resides in the periplasm, a compartment that experiences changes in pH value, osmolality, ion strength and other parameters depending on the cell's environment. Hence, the cell needs robust peptidoglycan growth mechanisms to grow and divide ...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Pazos M,Peters K,Vollmer W

    更新日期:2017-04-01 00:00:00

  • Striking a balance: fungal commensalism versus pathogenesis.

    abstract::The environment is suffused with nearly countless types of fungi, and our immune systems must be tuned to cope with constant exposure to them. In addition, it is becoming increasingly clear that many surfaces of our bodies are colonized with complex populations of fungi (the mycobiome) in the same way that they are co...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Iliev ID,Underhill DM

    更新日期:2013-06-01 00:00:00

  • Growth rate and cell size: a re-examination of the growth law.

    abstract::Research into the mechanisms regulating bacterial cell size has its origins in a single paper published over 50 years ago. In it Schaechter and colleagues made the observation that the chemical composition and size of a bacterial cell is a function of growth rate, independent of the medium used to achieve that growth ...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Vadia S,Levin PA

    更新日期:2015-04-01 00:00:00

  • The roles of zinc and copper sensing in fungal pathogenesis.

    abstract::All organisms must secure essential trace nutrients, including iron, zinc, manganese and copper for survival and proliferation. However, these very nutrients are also highly toxic if present at elevated levels. Mammalian immunity has harnessed both the essentiality and toxicity of micronutrients to defend against micr...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Ballou ER,Wilson D

    更新日期:2016-08-01 00:00:00

  • Heterocyst development in Anabaena.

    abstract::Many filamentous nitrogen-fixing cyanobacteria protect nitrogenase from oxygen in differentiated cells called heterocysts. Heterocyst development is controlled by the availability of nitrogen compounds in the environment and by intrinsic factors that regulate the frequency and pattern of heterocysts along vegetative c...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Golden JW,Yoon HS

    更新日期:2003-12-01 00:00:00

  • Plasticity in mast cell responses during bacterial infections.

    abstract::Mast cells (MCs) have been implicated in orchestrating the host's early innate immune and adaptive immune responses in several models of acute bacterial infections. Most of this activity results in early clearance of the bacteria and timely resolution of infection. However, during chronic infections because of the pro...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Chan CY,St John AL,Abraham SN

    更新日期:2012-02-01 00:00:00

  • Immune control of phagosomal bacteria by p47 GTPases.

    abstract::Sequestered from the action of complement, antibody and lytic peptides, phagosomal pathogens pose a unique problem for the innate immune system both in terms of detection and disposal. An immunologically induced 47-kDa (p47) GTPase family recruited to nascent phagosomes (PGs) has provided new insights into how vertebr...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: MacMicking JD

    更新日期:2005-02-01 00:00:00

  • Toxins from anaerobic bacteria: specificity and molecular mechanisms of action.

    abstract::Major advances have been made in the past five years in the identification of cellular targets of toxins produced by anaerobic bacteria. These targets include the vesicular membrane docking and fusion apparatus, the actin cytoskeleton, the signal transduction machinery and the cell membrane. The recent discovery that ...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Boquet P,Munro P,Fiorentini C,Just I

    更新日期:1998-02-01 00:00:00

  • Antibiotic efficacy-context matters.

    abstract::Antibiotic lethality is a complex physiological process, sensitive to external cues. Recent advances using systems approaches have revealed how events downstream of primary target inhibition actively participate in antibiotic death processes. In particular, altered metabolism, translational stress and DNA damage each ...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Yang JH,Bening SC,Collins JJ

    更新日期:2017-10-01 00:00:00

  • Reverse vaccinology.

    abstract::Biochemical, serological and microbiological methods have been used to dissect pathogens and identify the components useful for vaccine development. Although successful in many cases, this approach is time-consuming and fails when the pathogens cannot be cultivated in vitro, or when the most abundant antigens are vari...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Rappuoli R

    更新日期:2000-10-01 00:00:00

  • Analyses of clonality and the evolution of bacterial pathogens.

    abstract::The existence of bacterial clones was evident in early phenotypic studies that recognised high levels of similarity in geographically and temporally separated isolates. Multilocus sequence typing (MLST) has become the most common method for genetically characterizing clones of several bacterial pathogens, allowing the...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Feil EJ,Enright MC

    更新日期:2004-06-01 00:00:00

  • Fasciola hepatica, TGF-β and host mimicry: the enemy within.

    abstract::Helminths parasites undergo developmental changes and migration within their definitive host, in addition to establishing chronic infection. Essential to this is the evasion of host immune responses; the canonical Th2 response is effective at removing parasites resident in the intestine. Conversely, helminths also pro...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Musah-Eroje M,Flynn RJ

    更新日期:2018-12-01 00:00:00

  • Silencing of foreign DNA in bacteria.

    abstract::Xenogeneic silencing proteins facilitate horizontal gene transfer by silencing expression of AT-rich sequences. By virtue of their activity these proteins serve as master regulators of a variety of important functions including motility, drug resistance, and virulence. Three families of silencers have been identified ...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Ali SS,Xia B,Liu J,Navarre WW

    更新日期:2012-04-01 00:00:00

  • Single-cell reporters for pathogen responses to antimicrobial host attacks.

    abstract::Host-pathogen interactions are often heterogeneous involving individual encounters between host and pathogen cells with diverse molecular mechanisms, response networks, and diverging outcomes. Single-cell reporters can identify the various types of interactions and participating pathogen subsets, help to unravel under...

    journal_title:Current opinion in microbiology

    pub_type: 杂志文章,评审


    authors: Roche B,Bumann D

    更新日期:2021-02-01 00:00:00