Modulation of natural killer cell activity by viruses.

Abstract:

:Since their discovery, our understanding of NK cells has evolved from branding them marginal innate immunity cells to key players in anti-viral and anti-tumor immunity. Importance of NK cells in control of various viral infections is perhaps best illustrated by the existence of plethora of viral mechanisms aimed to modulate their function. These mechanisms include not only virally encoded immunoevasion proteins but also viral miRNA. Moreover, the evidence has been accumulated supporting the role of viral immunoevasion of NK cells in viral pathogenesis in vivo.

journal_name

Curr Opin Microbiol

authors

Lisnić VJ,Krmpotić A,Jonjić S

doi

10.1016/j.mib.2010.05.011

subject

Has Abstract

pub_date

2010-08-01 00:00:00

pages

530-9

issue

4

eissn

1369-5274

issn

1879-0364

pii

S1369-5274(10)00087-1

journal_volume

13

pub_type

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