Combination of inhaled nitric oxide therapy and inverse ratio ventilation in patients with sepsis-associated acute respiratory distress syndrome.

Abstract:

:Inverse ratio ventilation (IRV) is a ventilatory technique that uses an inspiratory to expiratory ratio (I:E) greater than 1:1. We studied the effects of mechanical ventilation with an I:E of 1:3, 1:1, and 2:1 on arterial oxygenation in 10 patients with sepsis-associated acute respiratory distress syndrome (ARDS). At each I:E, patients received 0 and 4 ppm of inhaled nitric oxide (INO) in random order for 30 min. Respiratory and cardiovascular parameters were measured. Of the 10 patients studied, 7 responded to IRV and 3 did not. An increase in the I:E and the addition of INO significantly improved arterial oxygenation in the responders (p < 0. 0001 and p < 0.006, respectively). The combination of an increase in the I:E and INO had an additive effect on arterial oxygenation. The combined use of IRV and INO is a more effective method of avoiding hypoxemia than either INO or IRV alone.

journal_name

Artif Organs

journal_title

Artificial organs

authors

Okamoto K,Kukita I,Hamaguchi M,Kikuta K,Matsuda K,Motoyama T

subject

Has Abstract

pub_date

2000-11-01 00:00:00

pages

902-8

issue

11

eissn

0160-564X

issn

1525-1594

pii

aor6554-2

journal_volume

24

pub_type

临床试验,杂志文章,随机对照试验
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    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2011.01421.x

    authors: Mohammadi HM,Ghafar-Zadeh E,Sawan M

    更新日期:2012-07-01 00:00:00

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    journal_title:Artificial organs

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    doi:10.1111/j.1525-1594.2007.00398.x

    authors: Suzuki M,Okahisa T,Sogabe M,Iwaki H,Okita Y,Ohnishi Y,Ito S

    更新日期:2007-05-01 00:00:00

  • End-point temperature of rewarming after hypothermic cardiopulmonary bypass in pediatric patients.

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    journal_title:Artificial organs

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/j.1525-1594.2005.00149.x

    authors: Kim WG,Yang JH

    更新日期:2005-11-01 00:00:00

  • Heat exchangers for cardioplegia systems: in vitro study of four different concepts.

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    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.2003.07240.x

    authors: Drummond M,Novello WP,de Arruda AC,Braile DM

    更新日期:2003-05-01 00:00:00

  • Computational fluid dynamics prediction of blood damage in a centrifugal pump.

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    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.2003.00026.x

    authors: Song X,Throckmorton AL,Wood HG,Antaki JF,Olsen DB

    更新日期:2003-10-01 00:00:00

  • Transcutaneous monitoring of blood gas tensions in patients on intermittent peritoneal dialysis.

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    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1988.tb02768.x

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    更新日期:1988-06-01 00:00:00

  • Effect of filtration leukocytapheresis therapy: modulation of white blood cell enzyme activities in patients with rheumatoid arthritis.

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    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.2002.06834.x

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    更新日期:2002-04-01 00:00:00

  • Further development of hybrid functional electrical stimulation orthoses.

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    journal_title:Artificial organs

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1525-1594.1997.tb04648.x

    authors: Yang L,Granat MH,Paul JP,Condie DN,Rowley DI

    更新日期:1997-03-01 00:00:00

  • A comparative study between flow visualization and computational fluid dynamic analysis for the sun medical centrifugal blood pump.

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    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2004.07161.x

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    更新日期:2004-05-01 00:00:00

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    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.1998.06130.x

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    更新日期:1998-06-01 00:00:00

  • Predictive Factors Upon Discontinuation of Renal Replacement Therapy for Long-Term Chronic Dialysis and Death in Acute Kidney Injury Patients.

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    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.12927

    authors: Yang T,Sun S,Lin L,Han M,Liu Q,Zeng X,Zhao Y,Li Y,Su B,Huang S,Yang L

    更新日期:2017-12-01 00:00:00

  • Short hemodialysis: long-term mortality and morbidity.

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    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1986.tb02541.x

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    更新日期:1986-06-01 00:00:00

  • The OregonHeart Total Artificial Heart: Design and Performance on a Mock Circulatory Loop.

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    pub_type: 杂志文章

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    更新日期:2017-10-01 00:00:00

  • Methodology for identification of serum middle molecules.

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    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:

    authors: Buzio C,Montagna G,Calderini C,Manari A,Migone L

    更新日期:1981-01-01 00:00:00

  • Microcirculation and artificial heart research.

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    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1988.tb01529.x

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    更新日期:1988-02-01 00:00:00

  • Use of an integrated sideport for diagnosis and management of decreased flow rates in a programmable implanted insulin delivery system. Implantable Insulin Pump Trial Study Group.

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    journal_title:Artificial organs

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1525-1594.1996.tb04586.x

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    更新日期:1996-09-01 00:00:00

  • Fluid dynamic characteristics of the VentrAssist rotary blood pump.

    abstract::The VentrAssist pump has no shaft or seal, and the device is unique in design because the rotor is suspended passively by hydrodynamic forces, and urging is accomplished by an integrated direct current motor rotor that also acts as the pump impeller. This device has led to many challenges in its fluidic design, namely...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.2000.06584.x

    authors: Tansley G,Vidakovic S,Reizes J

    更新日期:2000-06-01 00:00:00

  • Bioengineered cartilage in a scaffold-free method by human cartilage-derived progenitor cells: a comparison with human adipose-derived mesenchymal stromal cells.

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    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/aor.12121

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  • Application of computational fluid dynamics techniques to blood pumps.

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    pub_type: 杂志文章

    doi:

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    journal_title:Artificial organs

    pub_type: 杂志文章

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  • Influence of reuse and of reuse sterilants on the first-use syndrome.

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    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1987.tb02645.x

    authors: Vanholder R,Ringoir S

    更新日期:1987-04-01 00:00:00

  • A Meta-Analysis of Renal Function After Adult Cardiac Surgery With Pulsatile Perfusion.

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    journal_title:Artificial organs

    pub_type: 杂志文章,meta分析

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    更新日期:2015-09-01 00:00:00

  • Systemic consequences of ventricular assist devices: alterations of coagulation, immune function, inflammation, and the neuroendocrine system.

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    journal_title:Artificial organs

    pub_type: 杂志文章,评审

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    更新日期:2002-11-01 00:00:00

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    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.1983.tb04170.x

    authors: Starobin IM,Zaĭko VM

    更新日期:1983-02-01 00:00:00

  • Sensitivity of the primary stability of a cementless hip stem to its position and orientation.

    abstract::Using computed tomography (CT)-based preoperative planning software, we can define with good accuracy the position of a cementless hip stem inside the host bone, but previous studies suggest that the pose the surgeon achieves during freehand surgery may differ from the planned one even by some millimeters. Advances in...

    journal_title:Artificial organs

    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2008.00577.x

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    更新日期:2008-07-01 00:00:00

  • Evaluation of Combined Extracorporeal Life Support and Continuous Renal Replacement Therapy on Hemodynamic Performance and Gaseous Microemboli Handling Ability in a Simulated Neonatal ECLS System.

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    pub_type: 杂志文章

    doi:10.1111/aor.12987

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    更新日期:2018-04-01 00:00:00

  • Promigratory activity of oxytocin on umbilical cord blood-derived mesenchymal stem cells.

    abstract::Recent studies show that oxytocin has various effects on cellular behaviors. Oxytocin is reported to stimulate cardiomyogenesis of embryonic stem cells and endothelial cell proliferation. Mesenchymal stem cells (MSCs) are widely used for cardiac repair, and we elucidated the effect of oxytocin on umbilical cord derive...

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    pub_type: 杂志文章

    doi:10.1111/j.1525-1594.2009.00894.x

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  • Is serum albumin a marker of nutritional status in hemodialysis patients without evidence of inflammation?

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    pub_type: 杂志文章

    doi:10.1046/j.1525-1594.2003.07273.x

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  • A pilot study of piracetam in cuprophan hemodialysis.

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    journal_title:Artificial organs

    pub_type: 临床试验,杂志文章,随机对照试验

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    authors: Grekas D,Alivanis P,Karamouzis M,Pyrpasopoulos M,Tourkantonis A

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  • Pulsatile in vitro simulation of the pediatric univentricular circulation for evaluation of cardiopulmonary assist scenarios.

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    doi:10.1111/j.1525-1594.2009.00951.x

    authors: Dur O,Lara M,Arnold D,Vandenberghe S,Keller BB,DeGroff C,Pekkan K

    更新日期:2009-11-01 00:00:00