Use of an integrated sideport for diagnosis and management of decreased flow rates in a programmable implanted insulin delivery system. Implantable Insulin Pump Trial Study Group.

abstract：:We developed a new left ventricular (LV) assist catheter (transaortic valve from LV to femoral artery) that is implemented percutaneously and exerted as a synchronous pulsatile partial LV flow support with conventional intraaortic balloon pump (IABP) driving system and centrifugal pump system. We investigated whether ...

journal_title：Artificial organs

authors： Ide H,Yamaguchi A,Ino T,Matsumoto H,Fujimasa I

更新日期：1992-06-01 00:00:00

abstract：:Using urea and inulin as markers, we have developed a simple method to calculate intracellular and extracellular fluid volume in patients before and after hemofiltration therapy. During conventional hemofiltration using substitution fluid with a Na+ concentration of 140 mEq/L, a decrease in extracellular fluid volume ...

journal_title：Artificial organs

authors： Kimura G,Satani M,Kojima S,Kuroda K,Itoh K,Ikeda M

更新日期：1982-02-01 00:00:00

abstract：:Flow visualization experiments and computational fluid dynamic (CFD) analyses were performed and the results were compared to clarify the detailed fluid dynamic characteristics for the prototype design of a centrifugal pump, namely, an implantable ventricular assist system from Sun Medical, whose hemocompatibility was...

journal_title：Artificial organs

authors： Yamane T,Miyamoto Y,Tajima K,Yamazaki K

更新日期：2004-05-01 00:00:00

abstract：:Low molecular weight heparin (LMH) acts as an anticoagulation agent mainly through its anti-activated coagulation factor X (Xa) activity. Thrombelastography (TEG) is expected to be useful to monitor the dosage of LMH during hemodialysis because reaction time on TEG (TEG-r) is considered to reflect blood thromboplastin...

journal_title：Artificial organs

authors： Shinoda T,Arakura H,Katakura M,Shirota T,Nakagawa S

更新日期：1990-12-01 00:00:00

abstract：:Hypertension is an important primary etiology of end-stage renal disease as well as a major factor responsible for progression of renal disease due to other causes. Multiple genetic and environmental factors are responsible for the variable prevalence of hypertension in various parts of the world. Although the frequen...

journal_title：Artificial organs

authors： El-Khashab O

更新日期：2002-09-01 00:00:00

abstract：:Thrombosis and thromboembolism are the life-threatening clinical complications for patients supported or treated with prosthetic cardiovascular devices. The high mechanical shear stress within these devices is believed to be the major contributing factor to cause platelet activation (PA) and function alteration, leadi...

journal_title：Artificial organs

authors： Ding J,Chen Z,Niu S,Zhang J,Mondal NK,Griffith BP,Wu ZJ

更新日期：2015-07-01 00:00:00

abstract：:Bovine pericardium is a widely utilized biomaterial. Usually, after harvesting, it is advantageous that the pericardium be immersed in glycerol to improve its shelf life. This can induce some degree of toxicity in the material. The studies were performed in compliance with the rules of ISO 10993 and OECD 487, in the b...

journal_title：Artificial organs

authors： Rodas AC,Maizato MJ,Leirner AA,Pitombo RN,Polakiewicz B,Beppu MM,Higa OZ

更新日期：2008-04-01 00:00:00

abstract：:Extracorporeal membrane oxygenation (ECMO) is gaining importance in the perioperative management of lung transplant patients. To date, the ideal substance for anticoagulation of ECMO patients is still a matter of debate. In this study, we describe our experience with the use of low molecular weight heparin (LMWH) in c...

journal_title：Artificial organs

authors： Gratz J,Pausch A,Schaden E,Baierl A,Jaksch P,Erhart F,Hoetzenecker K,Wiegele M

更新日期：2020-06-01 00:00:00

abstract：:The polymer poly(ε-caprolactone) (PCL) has been used in the biomaterial field for its relatively inexpensive price and suitability for modification. Also, its chemical and biological properties are desirable for biomedical applications. The electrospinning process has been used for producing polymer fibers of PCL due ...

journal_title：Artificial organs

authors： Capellato P,Silva G,Popat K,Simon-Walker R,Alves Claro AP,Zavaglia C

更新日期：2020-08-01 00:00:00

abstract：:This paper presents an overview of the U.S. Food and Drug Administration's regulatory requirements for introducing medical device and diagnostic products into commercial distribution in the United States. For any specific product, the requirements vary depending upon the product's associated risks, classification, and...

journal_title：Artificial organs

authors： Morton WA

更新日期：1982-11-01 00:00:00

abstract：:Different methods are used, clinically and experimentally, to assist severely impaired heart function by means of skeletal muscle. The efficiency of these methods is restricted by skeletal muscle losing strength after transpositioning and during conditioning and not being sufficiently resistant to fatigue. This is mai...

journal_title：Artificial organs

authors： Lanmüller H,Sauermann S,Unger E,Schnetz G,Mayr W,Bijak M,Girsch W

更新日期：1999-04-01 00:00:00

abstract：:The new Advanced ventricular assist device (Advanced VAD) has many features such as improving pulsatility and preventing regurgitant flow during pump stoppage. The purpose of this study was to evaluate the effects of design modifications of the Advanced VAD on these features in vitro. Bench testing of four versions of...

journal_title：Artificial organs

authors： Miyamoto T,Byram N,Karimov JH,Adams J,Dessoffy R,Kuban BD,Gao S,Horvath DJ,Fukamachi K

更新日期：2019-10-01 00:00:00

abstract：:Although effects of biochemical modulation of stem cells have been widely investigated, only recent advances have been made in the identification of mechanical conditioning on cell signaling pathways. Experimental investigations quantifying the micromechanical environment of mesenchymal stem cells (MSCs) are challengi...

journal_title：Artificial organs

authors： Ghaemi RV,Vahidi B,Sabour MH,Haghighipour N,Alihemmati Z

更新日期：2016-03-01 00:00:00

abstract：:Atrial connections in a single-unit total artificial heart (TAH) may be difficult to make because of the rigidity of the device and the fixed position of the atrial inlets. We developed a technique to separate the natural atrial borders in an experimental implantation of a unitary TAH. In this technique, the interatri...

journal_title：Artificial organs

authors： Frazier OH,Matsuwaka R,Parnis SM,Furusho N,McGee MG,Fuqua JM

更新日期：1995-08-01 00:00:00

abstract：:The existence of acquired von Willebrand syndrome (AVWS) in patients with continuous flow left ventricular assist devices (LVADs) is well documented and has been verified by numerous investigators. AVWS has not been observed to occur in pulsatile devices such as the SynCardia total artificial heart (TAH), the HeartMat...

journal_title：Artificial organs

authors： Rosenberg G,Siedlecki CA,Jhun CS,Weiss WJ,Manning K,Deutsch S,Pierce W

更新日期：2018-12-01 00:00:00

abstract：:We have been developing a new type of centrifugal pump for long-term use. The magnetically suspended centrifugal pump (MSCP) contains no shaft and seal so that long life expectancy is predicted. Paracorporeal left ventricular (LV) assist circulation between the left atrium and the descending aorta was instituted using...

journal_title：Artificial organs

authors： Yamada T,Nishimura K,Park CH,Kono S,Yuasa S,Tsukiya T,Akamatsu T,Matsuda K,Ban T

更新日期：1997-07-01 00:00:00

abstract：:The blood flow through the hemofilter device is the key point for ultrafiltrate production during continuous arteriovenous hemofiltration. It mainly depends on arteriovenous pressure gradient and vascular access, which is the major problem for arteriovenous hemofiltration in infants and small children. In infants, we ...

journal_title：Artificial organs

authors： Zobel G,Trop M,Beitzke A,Ring E

更新日期：1988-02-01 00:00:00

abstract：:A pseudo-one compartment model has been proposed to describe phosphorus kinetics during hemodialysis and the immediate post-dialysis period. This model assumes that phosphorus mobilization from tissues is proportional to the difference between the pre-dialysis serum concentration (a constant) and the instantaneous ser...

journal_title：Artificial organs

authors： Leypoldt JK,Agar BU,Cheung AK,Bernardo AA

更新日期：2017-11-01 00:00:00

abstract：:Current hemodialysis treatment is insufficient because of intermittent treatment and loss of tubular function. In order to overcome the loss of tubular function, a bioartificial kidney has been developed consisting of continuous hemofiltration (CHF) with 10 L/day of filtrate and a bioartificial tubule device using pro...

journal_title：Artificial organs

authors： Saito A

更新日期：2004-01-01 00:00:00

abstract：:The design criteria of an extracorporeal circuit suitable for pulsatile flow are quite different and more entangled than for steady flow. The time and costs of the design process could be reduced if mutual influences between the pulsatile pump and other extracorporeal devices were considered without experimental trial...

journal_title：Artificial organs

authors： Pennati G,Fiore GB,Laganà K,Fumero R

更新日期：2004-02-01 00:00:00

abstract：:The accurate representation of rotary blood pumps in a numerical environment is important for meaningful investigation of pump-cardiovascular system interactions. Although numerous models for ventricular assist devices (VADs) have been developed, modeling methods for rotary total artificial hearts (rTAHs) are still re...

journal_title：Artificial organs

authors： Nestler F,Bradley AP,Wilson SJ,Timms DL

更新日期：2014-03-01 00:00:00

abstract：:The purpose of this study was to characterize changes in hepatic venous pressures in patients with chronic hepatitis C. The histology and laboratory data from patients with chronic hepatitis C who underwent a transjugular liver biopsy (TJLB) and hepatic venous pressure gradient measurement were analyzed. Portal hypert...

journal_title：Artificial organs

authors： Khurana S,Simcox T,Twaddell W,Drachenberg C,Flasar M

更新日期：2010-07-01 00:00:00

abstract：:Although it is now understood that trained skeletal muscle can generate enough steady-state power to provide significant circulatory support, there are currently no means by which to tap this endogenous energy source to aid the failing heart. To that end, an implantable muscle energy converter (MEC) has been construct...

journal_title：Artificial organs

authors： Trumble DR,Melvin DB,Byrne MT,Magovern JA

更新日期：2005-09-01 00:00:00

abstract：:Molecular biology has been moving swiftly toward clarifying the entire genome of organisms, including human. The human genome efforts that promote this transaction are characterized by the large-scale, high throughput production of data about the structure of the genome of the molecular level and its computer-assisted...

journal_title：Artificial organs

authors： Matsubara K

更新日期：1996-08-01 00:00:00

abstract：:Many types of rotary blood pumps and pump control methods have recently been developed with the goal of clinical use. From experiments, we know that pump flow spontaneously increases during exercise without changing pump control parameters. The purpose of this study was to determine the hemodynamics associated with th...

journal_title：Artificial organs

authors： Akimoto T,Yamazaki K,Litwak P,Litwak KN,Tagusari O,Mori T,Antaki JF,Kameneva MV,Watach MJ,Umezu M,Tomioka J,Kormos RL,Koyanagi H,Griffith BP

更新日期：1999-08-01 00:00:00

abstract：:An apparatus has been contructed to regulate ultrafiltration accurately during dialysis. The principle of the apparatus is that, per unit of time, exactly the same amount of dialysate is introduced into the dialyzer as is discharged from it. The apparatus consists of two isovolumetric pumps connected in line. The four...

journal_title：Artificial organs

authors： Flendrig JG,Carpay WM,Dekkers WT

更新日期：1978-05-01 00:00:00

abstract：:What the most causative factor affecting hemolysis is still controversial. To resolve this problem, we investigated the relationship between hemolysis and heat generation in six types of centrifugal blood pumps (Bio-Pump, Delphin, Capiox, Nikkiso, Isoflow, and Toyobo). The analyzed parameters were index of hemolysis i...

journal_title：Artificial organs

authors： Araki K,Taenaka Y,Masuzawa T,Tatsumi E,Wakisaka Y,Watari M,Nakatani T,Akagi H,Baba Y,Anai H

更新日期：1995-09-01 00:00:00

abstract：:In cardiac surgeries, it is frequently necessary to make the external blood circulation and oxygenation artificially. This procedure is called extracorporeal circulation (EC) or heart-lung bypass. During EC, one of the most important parameters, which demands continuous monitoring, is the blood flow. In many cases, th...

journal_title：Artificial organs

authors： Dantas RG,Costa ET

更新日期：2000-03-01 00:00:00

abstract：:Although several left ventricular assist devices (LVADs) have been used widely, remote monitoring of LVAD parameters has been available only recently. We present our remote monitoring experience with an axial-flow LVAD (HeartAssist-5, MicroMed Cardiovascular, Inc., Houston, TX, USA). Five consecutive patients who were...

journal_title：Artificial organs

authors： Pektok E,Demirozu ZT,Arat N,Yildiz O,Oklu E,Eker D,Ece F,Ciftci C,Yazicioglu N,Bayindir O,Kucukaksu DS

更新日期：2013-09-01 00:00:00

abstract：:A physiological controller is a key component to optimize the performance of left ventricular assist devices (LVADs) from short term to long term (10-20 years). The difficulties of its design lie in the inaccurate modeling of any particular human cardiovascular system because of limited knowledge, the large fluctuatio...

journal_title：Artificial organs

authors： Wu Y,Allaire PE,Tao G,Adams M,Liu Y,Wood H,Olsen DB

更新日期：2004-10-01 00:00:00