Abstract：
INTRODUCTION:We examined the relationships between insulin-like growth factor I (IGF-I), its binding protein (IGFBP-3), body composition, and bone mineral density (BMD) in collegiate runners (N = 13), gymnasts (N = 10), and noncompetitive women (N = 10). METHODS:Subjects were evaluated by dual-energy x-ray absorptiometry for body composition and BMD of the spine, hip, and whole body, fasting serum levels of IGF-I and IGFBP-3, and dietary intake. The ratio IGF-I/IGFBP-3 was calculated as a marker of IGF-I bioavailability. RESULTS:In ANOVA, IGF-I and IGF-I/IGFBP-3 in athletes with oligomenorrhea and amenorrhea did not differ from eumenorrheic athletes; thus, values were pooled. Lean/height2 and bone mass at the hip and spine were higher in gymnasts than runners and controls. Total caloric intake was similar between groups. IGF-I and IGF-I/IGFBP-3 differed between groups with gymnasts having higher IGF-I values than runners (397+/-58 vs 288+/-73 ng x mL(-1), P < 0.001) and higher IGF-I/IGFBP-3 than controls and runners (0.065+/-0.009 vs 0.056+/-0.008 vs 0.045+/-0.009, P = 0.0001). In simple regression, IGF-I and IGF-/IGFBP-3 were related to lean/height2 and BMD of the lumbar spine and hip (P < 0.01-0.0001). IGF-I and IGF-I/IGFBP-3 were multicollinear; thus, the ratio was used in subsequent stepwise regression. Lean mass, corrected for body surface area (height2), independently predicted spine and trochanteric BMD (R2 = 0.26, 0.28, respectively), whereas IGF-I/IGFBP-3 and lean/height2 together contributed to 48% of the variance in femoral neck BMD. CONCLUSION:We conclude that, in this group of young adult women, lower BMD in runners may be due, in part, to lower levels of IGF-I and the ratio of IGF-I-to-IGFBP-3 and that IGF-I may mediate the relationship between bone and lean mass.
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Snow CM,Rosen CJ,Robinson TLdoi
10.1097/00005768-200011000-00013subject
Has Abstractpub_date
2000-11-01 00:00:00pages
1902-7issue
11eissn
0195-9131issn
1530-0315journal_volume
32pub_type
杂志文章abstract：:Conflicting data on the alterations in the maximal exercise response to beta blockade (BB) may be the result of differences in the length of time the subject has been on medication, i.e., hours vs days. The purpose of this study was to examine maximal exercise responses during acute and chronic administration of BB. T...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1988-12-01 00:00:00
abstract：:In a variety of experimental models, hypoxia causes a shift in substrate use to favor increased dependence on glucose. One explanation for this phenomenon is a selective advantage derived from the increased metabolic economy (more ATP derived per unit oxygen consumed) that results when glucose is oxidized rather than ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e3181729dd3
更新日期：2008-08-01 00:00:00
abstract：INTRODUCTION:Parents play a critical role in shaping children's attitudes, beliefs, and behaviors, including those around physical activity and inactivity. Our ability to identify which practices effectively promote children's physical activity and limit inactivity is limited by existing measurement instruments. This p...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e31829d27de
更新日期：2013-12-01 00:00:00
abstract：:The papers in this supplement to Medicine and Science in Sports and Exercise seek to summarize our knowledge of the dose-response relationship of exercise with a variety of health outcomes. This type of rigorous evidence summation has become quite popular in the past 10 years as health care providers and policymakers ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-200106001-00004
更新日期：2001-06-01 00:00:00
abstract：PURPOSE:To examine longitudinal change in cardiorespiratory fitness and odds of incident sleep problems. METHODS:A cohort of 7368 men and 1155 women, age 20-85 yr, was recruited from the Aerobics Center Longitudinal Study. The cohort did not complain of sleep problems, depression, or anxiety at their first clinic visi...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000000506
更新日期：2015-05-01 00:00:00
abstract：PURPOSE:One purpose was to test the hypothesis that anxiety reductions following exercise are caused by a "time out" from daily cares and worries, and the second purpose was to document the magnitude of the change in state anxiety after exercise in high trait anxious females. METHODS:Anxious women (N = 14) completed f...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/00005768-199807000-00013
更新日期：1998-07-01 00:00:00
abstract：PURPOSE:This study aimed to quantify the repeated oxygen deficits attained during intermittent endurance exercise by measuring oxygen consumption (V˙O2) and oxygen demand (V˙O2) throughout a simulated roller ski race. METHODS:Eight male elite cross-country skiers (V˙O2peak, 77.4 ± 4.4 mL·kg⋅min) raced a 13.5-km roller...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000002209
更新日期：2020-04-01 00:00:00
abstract：:Young children's regular participation in physical activity is important not only to prevent excess weight gain and avoid chronic health problems but also to promote optimal physical, social, and psychological development. Given the large number of children enrolled in some form of out-of-home child care, this setting...
journal_title：Medicine and science in sports and exercise
pub_type：
doi：10.1249/MSS.0b013e3181ce9f85
更新日期：2010-03-01 00:00:00
abstract：BACKGROUND:Training intensity may play a key role in magnifying the protective effect of physical exercise against nonalcoholic fatty liver disease (NAFLD). PURPOSE:This study aimed to test the hypothesis that vigorous-intensity and interval training is as effective as moderate-intensity and continuous exercise traini...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000000595
更新日期：2015-08-01 00:00:00
abstract：:We studied the stimulus-response characteristics of cardiopulmonary baroreflex control of forearm vascular resistance (FVR) in four groups of male volunteer subjects: i) unfit, ii) physically fit, iii) before and after 10 wk of endurance training (chronic blood volume expansion), and iv) before and after acute blood v...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：
更新日期：1993-06-01 00:00:00
abstract：PURPOSE:Patellar tendon abnormality (PTA) on diagnostic imaging is part of the diagnostic criteria for patellar tendinopathy. PTA and altered landing strategies are primary risk factors that increase the likelihood of asymptomatic athletes developing patellar tendinopathy. Therefore, the aim of this study was to examin...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e318275e0f2
更新日期：2013-03-01 00:00:00
abstract：INTRODUCTION:The effects of glargine/glulisine insulin regimen on exercise blood glucose (BG) and strategies to limit exercise-induced hypoglycemia are not well documented. Intermittent high-intensity exercise has been proposed to prevent hypoglycemia, but its effect in participants with type 1 diabetes using glargine/...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0b013e31826c6ad3
更新日期：2013-01-01 00:00:00
abstract：PURPOSE:The purpose of this study was to compare architectural characteristics of leg muscles of sprinters and distance runners. METHODS:Skeletal muscle architectural characteristics were studied in 23 elite male 100-m sprinters (SPR, 10.0-10.9 s for 100 m), 24 elite male distance runners (DR, 13.5-14.5 min for 5000 m...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-200006000-00014
更新日期：2000-06-01 00:00:00
abstract：PURPOSE:Lateral compartment osteoarthritis accompanied by abnormal knee biomechanics is frequently reported in individuals with knee osteoarthritis after anterior cruciate ligament reconstruction (ACLR). The aim of this study was to evaluate changes in knee biomechanics produced by an adjusted and unadjusted varus knee...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000001201
更新日期：2017-06-01 00:00:00
abstract：INTRODUCTION:Physical endurance can be limited by muscle glycogen stores, in that glycogen depletion markedly reduces external work. During carbohydrate restriction, the liver synthesizes the ketone bodies, D-β-hydroxybutyrate, and acetoacetate from fatty acids. In animals and in the presence of glucose, D-β-hydroxybut...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0000000000001292
更新日期：2017-09-01 00:00:00
abstract：:Twelve male swimmers were studied psychologically before, during, and after 10 d of increased training. Daily training distance was increased from 4,000 to 9,000 m.d-1, and intensity was maintained at 94% of VO2max. Three of the swimmers were unable to tolerate the increased training load, and they did the same distan...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/00005768-198808000-00014
更新日期：1988-08-01 00:00:00
abstract：PURPOSE:To compare four different methods of measuring physical activity (PA) in adult women under free-living conditions. METHODS:Twelve women participated in a 7-d period during which PA was assessed via self-report, accelerometry and step-counting. Subjects wore at the waist a Tritrac-R3D accelerometer, a Computer ...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-200007000-00021
更新日期：2000-07-01 00:00:00
abstract：PURPOSE:Aerobic training (AT) and high-intensity intermittent training (HIIT) reduce arterial stiffness, whereas resistance training (RT) induces deterioration of or no change in arterial stiffness. However, the molecular mechanism of these effects of different exercise modes remains unclear. This study aimed to clarif...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,随机对照试验
doi：10.1249/MSS.0000000000001567
更新日期：2018-06-01 00:00:00
abstract：PURPOSE:The objective of this study is to determine whether childhood muscular fitness phenotypes (strength, endurance, and power) are independently associated with adult metabolic syndrome (MetS). METHODS:We conducted a longitudinal study including 737 participants who had muscular fitness measures in 1985 when age 9...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0000000000000955
更新日期：2016-09-01 00:00:00
abstract：:This article focuses on sports related spinal cord and nerve injuries, ranging from mild "stinger" syndrome to complete quadriplegia. Particular emphasis is placed on recommendations for return to competition after such injuries. Cervical spinal cord symptoms after a spine injury from contact sports require a more pre...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199707001-00005
更新日期：1997-07-01 00:00:00
abstract：:The present study examined the validity of selected bioelectrical impedance (BIA) equations for estimating percent fat (% fat) in males and compared their validity with that of a commonly used skinfold equation (Sum3). One-hundred twenty-two Caucasian males (X +/- SD = 12.5 +/- 5.8% fat, as determined by underwater we...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1097/00005768-199604000-00019
更新日期：1996-04-01 00:00:00
abstract：PURPOSE:This study aimed to examine whether long-term fish oil (FO) supplementation is associated with a lower risk of mobility disability and enhances benefits of physical activity (PA). METHODS:A total of 1635 sedentary adults age 70 to 89 yr from the Lifestyle Interventions and Independence for Elders single-blinde...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1249/MSS.0000000000002195
更新日期：2020-04-01 00:00:00
abstract：PURPOSE:To determine which combination of landing protocol and analysis technique would be the most effective at detecting differences in dynamic stability between healthy subjects and subjects with functional ankle instability (FAI). METHODS:Fifty-eight subjects participated in this investigation: 29 healthy individu...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/01.mss.0000149887.84238.6c
更新日期：2005-02-01 00:00:00
abstract：UNLABELLED:Several investigators have demonstrated that chronic eccentric leg cycling is an effective method for improving lower body neuromuscular function (e.g., quadriceps muscle size, strength, and mobility) in a variety of patient and athletic populations. To date, there are no reports of using eccentric arm cycli...
journal_title：Medicine and science in sports and exercise
pub_type： 临床试验,杂志文章
doi：10.1249/MSS.0b013e318269c79c
更新日期：2013-01-01 00:00:00
abstract：INTRODUCTION:Loud sounds can decrease reaction time (RT) and increase force generated during voluntary contractions. Accordingly, we hypothesized that the loud starter's pistol at the Olympic Games allows runners closer to the starter to react sooner and stronger than runners farther away. METHODS:RT for the 100/110 m...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e31816770e1
更新日期：2008-06-01 00:00:00
abstract：:In this study the gross efficiency of swimming was determined in a group of male (N = 6) and female (N = 4) competitive swimmers. The gross efficiency is defined as the ratio of the power output (W) to the power input (W). In a range of swimming velocities (0.95-1.6 m.s-1), the power input (rate of energy expenditure,...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1990-06-01 00:00:00
abstract：:Poliomyelitis is an acute viral disease that attacks the brain and the ventral horn of the spinal cord. Damage to the lower motor neurons usually results in atrophy and weakness of muscle groups, perhaps paralysis and possibly deformity. A second type, bulbar poliomyelitis, infects the medulla oblongata and may result...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：
更新日期：1993-04-01 00:00:00
abstract：:: The relevance of translational medicine (bringing basic science methods "to the bed of patients") is universally recognized. Too often, however, the tools to be applied translationally are thought to derive only from the "-omics" (genomics, proteomics, transcriptomics, metabolomics, etc.) world. The failures of this...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章,评审
doi：10.1249/MSS.0000000000002056
更新日期：2019-11-01 00:00:00
abstract：:The purpose of this study was to compare gastric emptying (GE) responses during intense, prolonged cycling and running. It is important to discern whether gastric emptying (GE) responses are exercise-mode specific, since the findings of cycling and running studies are often compared and applied to one another. Ten mal...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：
更新日期：1991-03-01 00:00:00
abstract：PURPOSE:Development of an endurance training-overtraining protocol for Wistar rats that includes increased workload and is characterized by analyses of performance and biomarkers. METHODS:The running protocol lasted 11 wk: 8 wk of daily exercise sessions followed by 3 wk of increasing training frequency (two, three, a...
journal_title：Medicine and science in sports and exercise
pub_type： 杂志文章
doi：10.1249/MSS.0b013e318191259c
更新日期：2009-05-01 00:00:00
