Abstract:
:We studied the stimulus-response characteristics of cardiopulmonary baroreflex control of forearm vascular resistance (FVR) in four groups of male volunteer subjects: i) unfit, ii) physically fit, iii) before and after 10 wk of endurance training (chronic blood volume expansion), and iv) before and after acute blood volume expansion. We assessed the relationship between reflex stimulus, i.e., changes in central venous pressure and response, i.e., FVR, during unloading of cardiopulmonary mechanoreceptors with lower body negative pressure (LBNP, 0 to -20 mm Hg). The slope of the linear relationship between FVR and CVP, the index of the responsiveness of this baroreflex, was significantly diminished (> 50%) in the fit subjects compared with the unfit. The slope of the FVR-CVP relationship was inversely correlated with the subject's total blood volume, suggesting that blood volume expansion was related to the attenuated CP baroreflex. In the exercise training study, maximal oxygen consumption and blood volume increased following 10 wk of endurance training (N = 14) but were unchanged in the time control group (N = 7). The slope of the FVR-CVP relationship was significantly reduced (32%) following 10 wk of training but was unchanged in the time control group. The reduction in slope of the FVR-CVP relationship was inversely related to the increase in blood volume associated with exercise training. Acute blood volume expansion 8 ml.kg-1 body weight with 5% human serum albumin solution) significantly reduced the slope of the FVR-CVP relationship. These data support the hypothesis that the attenuated forearm vascular reflex in physically fit individuals is related to a training-induced hypervolemia.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Med Sci Sports Exercjournal_title
Medicine and science in sports and exerciseauthors
Mack GW,Convertino VA,Nadel ERsubject
Has Abstractpub_date
1993-06-01 00:00:00pages
722-6issue
6eissn
0195-9131issn
1530-0315journal_volume
25pub_type
杂志文章,评审abstract::Exercise and noise exposure causes temporary hearing loss. Yet, a direct relationship may exist between cardiovascular health and hearing. The purpose of this study was to determine whether noise and exercise caused different levels of hearing loss depending on one's cardiovascular fitness. Twenty-eight volunteers wer...
journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
doi:
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journal_title:Medicine and science in sports and exercise
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journal_title:Medicine and science in sports and exercise
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journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
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pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章
doi:10.1249/00005768-198206000-00006
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,随机对照试验
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journal_title:Medicine and science in sports and exercise
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journal_title:Medicine and science in sports and exercise
pub_type: 临床试验,杂志文章
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journal_title:Medicine and science in sports and exercise
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journal_title:Medicine and science in sports and exercise
pub_type: 杂志文章,评审
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journal_title:Medicine and science in sports and exercise
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