Abstract：
:We have investigated oocyte development in Hydra vulgaris, a member of one of the oldest metazoan phyla. We show that oocyte determination involves a mechanism that establishes a subset of precursor interstitial cells competent to differentiate into oocytes. The oocyte is singled out from this subset and the competence of the remaining cells to become oocytes dramatically decreases as they adopt the alternative nurse cell fate. Progression through the nurse cell differentiation program requires the presence of the oocyte. When the oocyte is removed from the egg field, nurse cells abort their differentiation program, undergo apoptosis, and are phagocytosed and degraded by somatic epithelial cells. However, in the presence of the oocyte, nurse cells differentiate and enter an unusual apoptosis program where they are phagocytosed by the oocyte, but are not degraded. We show that the oocyte is able to induce this unusual apoptosis program in immature nurse cells that have not completed differentiation. A new model for oocyte development in Hydra is discussed.
journal_name
Dev Bioljournal_title
Developmental biologyauthors
Miller MA,Technau U,Smith KM,Steele REdoi
10.1006/dbio.2000.9790subject
Has Abstractpub_date
2000-08-15 00:00:00pages
326-38issue
2eissn
0012-1606issn
1095-564Xpii
S0012-1606(00)99790-2journal_volume
224pub_type
杂志文章abstract：:The vertebrate eye anlage grows out of the brain and folds into bilayered optic cups. The eye is patterned along multiple axes, precisely controlled by genetic programs, to delineate neural retina, pigment epithelium, and optic stalk tissues. Pax genes encode developmental regulators of key morphogenetic events, with ...
journal_title：Developmental biology
pub_type： 杂志文章
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更新日期：2021-01-09 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
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journal_title：Developmental biology
pub_type： 杂志文章
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journal_title：Developmental biology
pub_type： 杂志文章
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journal_title：Developmental biology
pub_type： 杂志文章
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journal_title：Developmental biology
pub_type： 杂志文章
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journal_title：Developmental biology
pub_type： 杂志文章
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journal_title：Developmental biology
pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：Developmental biology
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journal_title：Developmental biology
pub_type： 杂志文章
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/0012-1606(89)90127-9
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2008.02.035
更新日期：2008-05-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1006/dbio.1995.1024
更新日期：1995-01-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2007.01.015
更新日期：2007-04-15 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2008.06.036
更新日期：2008-09-15 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
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更新日期：2005-11-15 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
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journal_title：Developmental biology
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更新日期：1985-07-01 00:00:00
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journal_title：Developmental biology
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2004.05.034
更新日期：2004-09-15 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/j.ydbio.2008.01.030
更新日期：2008-04-15 00:00:00
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更新日期：2020-03-15 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
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更新日期：1989-10-01 00:00:00
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journal_title：Developmental biology
pub_type： 杂志文章
doi：10.1016/0012-1606(84)90140-4
更新日期：1984-02-01 00:00:00
