Abstract：
:Unequivocal proof that the activity of a localized cortical neuronal population provides sufficient basis for a specific cognitive function has rarely been obtained. We looked for such proof in monkeys trained to discriminate between two mechanical flutter stimuli applied sequentially to the fingertips. Microelectrodes were inserted into clusters of quickly adapting (QA) neurons of the primary somatosensory cortex (S1), and the first or both stimuli were then substituted with trains of current pulses during the discrimination task. Psychophysical performance with artificial stimulus frequencies was almost identical to that measured with the natural stimulus frequencies. Our results indicate that microstimulation can be used to elicit a memorizable and discriminable analog range of percepts, and shows that activation of the QA circuit of S1 is sufficient to initiate all subsequent neural processes associated with flutter discrimination.
journal_name
Neuronjournal_title
Neuronauthors
Romo R,Hernández A,Zainos A,Brody CD,Lemus Ldoi
10.1016/s0896-6273(00)81156-3subject
Has Abstractpub_date
2000-04-01 00:00:00pages
273-8issue
1eissn
0896-6273issn
1097-4199pii
S0896-6273(00)81156-3journal_volume
26pub_type
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