Abstract:
:Invasion of the visceral pleura is an important component of lung carcinoma staging, and in some studies is an independent prognostic indicator. Evaluation of invasion by H&E may be indeterminate. Elastic stains can be helpful but are performed rarely. We reviewed all lung carcinoma resections from 1993 for 13 histologic features potentially predictive of pleural invasion. Of 57 resections, 20 were indeterminate by H&E. Verhoeff-Van Gieson (VVG) stain revealed invasion in 8 cases, increasing the pathologic stage in 1. VVG stain was negative in 12 cases, 2 of which had been falsely reported as positive, decreasing the stage in 1. Angiolymphatic invasion and single-cell spread were significant predictors of invasion. Absence of both or the presence of intervening aerated parenchyma predicted lack of involvement in all cases. Elastic stains can provide prognostically important information, changing the pathologic stage in 4% of lung carcinoma resections overall and in 10% of cases indeterminate by H&E for pleural invasion.
journal_name
Am J Clin Patholjournal_title
American journal of clinical pathologyauthors
Bunker ML,Raab SS,Landreneau RJ,Silverman JFdoi
10.1093/ajcp/112.6.777subject
Has Abstractpub_date
1999-12-01 00:00:00pages
777-83issue
6eissn
0002-9173issn
1943-7722journal_volume
112pub_type
杂志文章abstract::We describe 13 cases in which the submucosa and muscularis mucosae of the gastrointestinal tract exhibited a focal or diffuse increase of elastin fibers. This elastosis or elastofibromatous change most commonly manifested as a colonic polyp and usually was found during screening colonoscopy. Gastric and small intestin...
journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/LBGT-CG1Q-CD96-M3NF
更新日期:2004-08-01 00:00:00
abstract::Antibody to hepatitis B core antigen (anti-HBc) has previously been recognized to be a sensitive marker of hepatitis B virus (HBV) infection. In addition, anti-HBc has recently been suggested to be a surrogate marker for non-A, non-B hepatitis agents in donated blood. The authors studied prospectively the HBV antigen ...
journal_title:American journal of clinical pathology
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journal_title:American journal of clinical pathology
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journal_title:American journal of clinical pathology
pub_type: 杂志文章
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journal_title:American journal of clinical pathology
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journal_title:American journal of clinical pathology
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journal_title:American journal of clinical pathology
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journal_title:American journal of clinical pathology
pub_type: 杂志文章
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更新日期:2008-08-01 00:00:00
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journal_title:American journal of clinical pathology
pub_type: 杂志文章
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journal_title:American journal of clinical pathology
pub_type: 杂志文章
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journal_title:American journal of clinical pathology
pub_type: 杂志文章
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更新日期:1991-04-01 00:00:00
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journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1309/DU7F-XYP8-1DF6-WM9E
更新日期:2001-11-01 00:00:00
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journal_title:American journal of clinical pathology
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更新日期:1981-01-01 00:00:00
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journal_title:American journal of clinical pathology
pub_type: 杂志文章
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更新日期:1995-06-01 00:00:00
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journal_title:American journal of clinical pathology
pub_type: 杂志文章
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更新日期:1993-06-01 00:00:00
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journal_title:American journal of clinical pathology
pub_type: 杂志文章
doi:10.1093/ajcp/aqy069
更新日期:2018-10-01 00:00:00
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journal_title:American journal of clinical pathology
pub_type: 杂志文章
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更新日期:2001-08-01 00:00:00
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journal_title:American journal of clinical pathology
pub_type: 杂志文章
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journal_title:American journal of clinical pathology
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journal_title:American journal of clinical pathology
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journal_title:American journal of clinical pathology
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journal_title:American journal of clinical pathology
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journal_title:American journal of clinical pathology
pub_type: 杂志文章
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journal_title:American journal of clinical pathology
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更新日期:1998-05-01 00:00:00
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更新日期:2008-03-01 00:00:00
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pub_type: 杂志文章
doi:10.1309/C8T8-YNB4-G3W4-5PRF
更新日期:2003-07-01 00:00:00