Reaction times are faster in HIV-seropositive patients on antiretroviral therapy: A preliminary report.

Abstract:

:We evaluated subclinical mental and motor slowing in 142 HIV-seropositive patients without dementia, using computerized simple and choice reaction time tasks and self-report measures of psychological distress. Patients on antiretroviral therapy at the time of testing (n = 79) had significantly faster choice reaction times (p < 0.05), indicating faster mental processing speed, than untreated patients (n = 63). These faster RTs could not be attributed to differences in age, education, risk factors, degree of immunosuppression, substance abuse history, peripheral neuropathy, or psychological distress. Reaction time tasks should be investigated further as potential outcome measures in clinical trials, particularly for subjects with few or no overt cognitive deficits.

authors

Martin EM,Pitrak DL,Novak RM,Pursell KJ,Mullane KM

doi

10.1076/jcen.21.5.730.867

subject

Has Abstract

pub_date

1999-10-01 00:00:00

pages

730-5

issue

5

eissn

1380-3395

issn

1744-411X

journal_volume

21

pub_type

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