Cerebral blood flow and neuropsychological functioning in elderly vascular disease patients.

Abstract:

:This study was designed to determine the relationships between positron emission tomography (PET)-based quantitative measures of cerebral blood flow and cerebrovascular reserve and neuropsychological functioning in elderly individuals with atherosclerotic vascular disease. It was hypothesized that cerebrovascular function would be significantly associated with neuropsychological functioning. Results showed that both baseline global cerebral blood flow and cerebrovascular reserve were significantly associated with global neuropsychological functioning, when controlling for age and sex. Cerebrovascular reserve was additionally associated with performance on measures of memory and attention. Additional research is needed to determine whether measures of cerebral blood flow can be used to predict cognitive decline.

authors

Moser DJ,Boles Ponto LL,Miller IN,Schultz SK,Menda Y,Arndt S,Nopoulos PC

doi

10.1080/13803395.2011.630653

subject

Has Abstract

pub_date

2012-01-01 00:00:00

pages

220-5

issue

2

eissn

1380-3395

issn

1744-411X

journal_volume

34

pub_type

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