Towards a behavioral typology of Alzheimer's patients.

Abstract:

:Neuropsychological test performance and estimates of regional rates of cortical glucose metabolism obtained via positron emission tomography are presented for patients with Alzheimer's disease (AD). Analyses of these data indicated the presence of distinct subgroups characterized by qualitatively different profiles of cognitive impairment and corresponding patterns of cerebral hypometabolism. No subgroup differences were noted with regard to age at onset or reported duration of symptoms. These findings indicate that, in a given individual, AD may initially invade a relatively circumscribed cortical region. Thus, although AD may constitute a single disease process, it does not result in a unitary neuropsychological syndrome.

authors

Martin A,Brouwers P,Lalonde F,Cox C,Teleska P,Fedio P,Foster NL,Chase TN

doi

10.1080/01688638608405178

subject

Has Abstract

pub_date

1986-10-01 00:00:00

pages

594-610

issue

5

eissn

1380-3395

issn

1744-411X

journal_volume

8

pub_type

杂志文章
  • A longitudinal analysis of neurocognitive function in unipolar depression.

    abstract::Neurocognitive function is reduced in major depression, but uncertainties remain about if and to what extent improvement in neurocognitive function follows remission of depressive symptoms. A total of 30 patients with Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition (DSM-IV) diagnosis of unipolar m...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803390601147686

    authors: Biringer E,Mykletun A,Sundet K,Kroken R,Stordal KI,Lund A

    更新日期:2007-11-01 00:00:00

  • Self-reported everyday memory and depression in patients with multiple sclerosis.

    abstract::Depression and memory difficulties are among the most common complaints voiced by patients with multiple sclerosis (MS). Nevertheless, little is known about how depression might affect patients' perceptions of their memory difficulties. The present investigation was designed to explore this issue. Results supported a ...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1076/jcen.26.2.200.28081

    authors: Bruce JM,Arnett PA

    更新日期:2004-04-01 00:00:00

  • Autopsy-confirmed Alzheimer's disease versus clinically diagnosed Alzheimer's disease in the Cache County Study on Memory and Aging: a comparison of quantitative MRI and neuropsychological findings.

    abstract::Atrophy of specific, regional, and generalized brain structures occurs as a result of the Alzheimer's disease (AD) process. Comparing AD patients with histopathological confirmation of the disease at autopsy to those without autopsy but who were clinically diagnosed using the same antemortem criteria will provide furt...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803390600826579

    authors: Fearing MA,Bigler ED,Norton M,Tschanz JA,Hulette C,Leslie C,Welsh-Bohmer K,Cache County Investigators.

    更新日期:2007-07-01 00:00:00

  • Some aspects of memory disorders clearly distinguish dementia of the Alzheimer's type from depressive pseudo-dementia.

    abstract::Two groups of patients affected by mild dementia of the Alzheimer's type (n = 42) or by depressive pseudo-dementia (n = 26) were given a modified version of the Rey's Auditory Verbal Learning Test. The two groups were roughly matched for overall level of cognitive impairment. The main purpose of the research was to de...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/01688639408402617

    authors: Gainotti G,Marra C

    更新日期:1994-02-01 00:00:00

  • Learning, forgetting, and retrieval of everyday material across the adult life span.

    abstract::Levels and rates of acquisition and amounts of forgetting of name-face associations and grocery list items were assessed in a sample of 1,921 normal participants that was divided into five age groups (i.e., 17-39, 40-49, 50-59, 60-69, and 70+). Retrieval was assessed via the consistent long-term retrieval score (CLTR)...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/01688639308402570

    authors: Youngjohn JR,Crook TH 3rd

    更新日期:1993-07-01 00:00:00

  • Modeling longitudinal change in motor and cognitive processing speed in presymptomatic Huntington's disease.

    abstract::Persons who have the genetic mutation responsible for Huntington's disease (HD) have been shown to exhibit lower cognitive test scores years prior to manifest HD. Most studies have examined cognitive performance in presymptomatic persons by using estimated times to manifest HD based on published algorithms. We followe...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803395.2011.574606

    authors: Maroof DA,Gross AL,Brandt J

    更新日期:2011-10-01 00:00:00

  • Decline in verbal memory in non-demented older adults.

    abstract::Decline in memory function was detected in 30% of healthy community-dwelling elderly over 6 years using a task assessing delayed word list recall. Individuals with memory decline over time also demonstrated relative deficits on additional tasks of memory and learning, a task of working memory and executive function, a...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13825580600954256

    authors: Cargin JW,Maruff P,Collie A,Shafiq-Antonacci R,Masters C

    更新日期:2007-10-01 00:00:00

  • Recovery versus retest effects in attention after closed head injury.

    abstract::Recovery in 60 patients with a closed-head injury (CHI) in the first year posttrauma was assessed repeatedly with a series of attention tests. A matched group of healthy subjects was tested at the same intervals to allow us to control for practice effects. The results of a multilevel analysis for longitudinal data sho...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1076/jcen.21.5.585.874

    authors: Spikman JM,Timmerman ME,Zomeren van AH,Deelman BG

    更新日期:1999-10-01 00:00:00

  • Measurement equivalence of neuropsychological tests across education levels in older adults.

    abstract:OBJECTIVE:The objective was to determine whether neuropsychological tests provide an equivalent measure of the same psychological constructs in older adults with low versus higher levels of education. METHOD:Confirmatory factor analysis was used to evaluate the fit of a three-factor model (Verbal Ability, Visuospatial...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803395.2014.967661

    authors: Brewster PW,Tuokko H,MacDonald SW

    更新日期:2014-01-01 00:00:00

  • Flexibility in children with autism spectrum disorders (ASD): inconsistency between neuropsychological tests and parent-based rating scales.

    abstract::In this study, we compared neuropsychological tests and parent-based ratings of flexibility in a sample of children with autism spectrum disorders (ASD). We investigated the discriminant validity of the domain-specific flexibility measures by comparison with the domain general measures, general behavioral problems, ge...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803395.2012.670209

    authors: Teunisse JP,Roelofs RL,Verhoeven EW,Cuppen L,Mol J,Berger HJ

    更新日期:2012-01-01 00:00:00

  • Absolute and relative temporal order memory for performed activities following stroke.

    abstract::Reconstructing the temporal order of events is a crucial part of episodic memory. The temporal dimension, however, is often discarded in clinical settings, and measurements of true temporal aspects of episodic memory are scarce. The present study assessed temporal memory in stroke patients and in age- and education-ma...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803395.2014.925093

    authors: Schoo LA,van Zandvoort MJ,Reijmer YD,Biessels GJ,Kappelle LJ,Postma A

    更新日期:2014-01-01 00:00:00

  • Implicit and explicit emotional processing in Parkinson's disease.

    abstract:INTRODUCTION:Our study investigated the ability of nondemented Parkinson's disease (PD) patients to explicitly identify emotional words and to show implicit sensitivity to these emotions in a task that did not require emotional processing. METHODS:Twelve PD patients and 12 healthy controls, matched for age and educati...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803395.2011.639296

    authors: Borg C,Bedoin N,Bogey S,Michael GA,Poujois A,Laurent B,Thomas-Antérion C

    更新日期:2012-01-01 00:00:00

  • Construct and predictive validity of the repeatable battery for the assessment of neuropsychological status in the evaluation of stroke patients.

    abstract::To evaluate the construct and predictive validity of a brief neuropsychological assessment battery, consecutive admissions to a hospital receiving inpatient treatment for stroke were tested with the Repeatable Battery for Assessment of Neuropsychological Status (RBANS) and other neuropsychological measures. Discrimina...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/138033990513564

    authors: Larson E,Kirschner K,Bode R,Heinemann A,Goodman R

    更新日期:2005-01-01 00:00:00

  • Exaggeration index for an expanded version of the auditory verbal learning test: robustness to coaching.

    abstract::Recent research suggests that effort detection measures based on patterns of neuropsychological performance may be more robust to coaching than traditional effort detection measures. In the present study, we evaluated the Exaggeration Index for an extended version of the Auditory Verbal Learning Test (EI-AVLTX), a rec...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803390490510121

    authors: Suhr J,Gunstad J,Greub B,Barrash J

    更新日期:2004-05-01 00:00:00

  • Examining Rey Complex Figure Test organization in healthy adults.

    abstract:INTRODUCTION:The Rey Complex Figure Test (RCFT) is a popular measure of visuospatial and executive functioning. Clinical interpretations of RCFT performance are partly based on how an individual approaches the task with piecemeal organization often considered indicative of impairment. This is despite little previous re...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803395.2015.1075473

    authors: Wilson NA,Batchelor J

    更新日期:2015-01-01 00:00:00

  • An investigation of attention, executive, and psychomotor aspects of cognitive fatigability.

    abstract:OBJECTIVE:Self-perceived mental fatigue is a common presenting symptom in many neurological diseases. Discriminating objective fatigability from self-perceived mental fatigue might facilitate neuropsychological diagnosis and treatment programs. However clinically valid neuropsychological instruments suitable for assess...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803395.2014.933779

    authors: Möller MC,Nygren de Boussard C,Oldenburg C,Bartfai A

    更新日期:2014-01-01 00:00:00

  • Subtle memory and attentional deficits revealed in an Irish stroke patient sample using domain-specific cognitive tasks.

    abstract::Stroke disrupts motor, sensory, and cognitive systems in survivors. Unlike in physical impairments, assessment of cognitive function is often inadequate, as no standardized procedure to monitor cognitive recovery post stroke exists. We evaluated a number of novel task-orientated tools designed to assess subtle cogniti...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803395.2012.690368

    authors: Duffin JT,Collins DR,Coughlan T,O'Neill D,Roche RA,Commins S

    更新日期:2012-01-01 00:00:00

  • The Satz-Mogel short form of the Wechsler Adult Intelligence Scale--revised: effects of global mental status and age on test-retest reliability.

    abstract::Abbreviated versions of the Wechsler Adult Intelligence Scale-Revised (WAIS-R) have been developed as time saving devices that provide accurate estimates of overall level of general intellectual functioning while decreasing test administration time. The Satz-Mogel short form of the WAIS-R has received substantial atte...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1076/1380-3395(200010)22:5;1-9;FT545

    authors: McPherson S,Buckwalter GJ,Tingus K,Betz B,Back C

    更新日期:2000-10-01 00:00:00

  • Inhibition and facilitation in schizotypy.

    abstract::Participants scoring high and low on a schizotypy scale (n=18 in each group) switched between naming words and naming colors in a Stroop task in congruent, neutral, and incongruent conditions. The findings were that, while being slower and less accurate overall than low schizotypes, the high schizotypy group did not d...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803390701336866

    authors: Cimino M,Haywood M

    更新日期:2008-02-01 00:00:00

  • Cannabis, alcohol use, psychological distress, and decision-making style.

    abstract:INTRODUCTION:There have been suggestions of hypofrontality in cannabis users. To understand cannabis-related differences in decisional processes, Janis and Mann's conflict model of decision making was applied to recreational cannabis smokers who varied in their alcohol use and level of psychological distress. METHOD:A...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803395.2016.1255311

    authors: Phillips JG,Ogeil RP

    更新日期:2017-09-01 00:00:00

  • Memory for faces in epileptic children before and after brain surgery.

    abstract::Memory for pairs of unfamiliar children's faces was investigated in 29 children and adolescents suffering from left (LTLE) or right (RTLE) temporal-lobe epilepsy, before and after temporal-lobe surgery. Both immediate and delayed memory were tested. Before surgery, RTLE subjects performed worse than either LTLE subjec...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/01688639408402670

    authors: Beardsworth ED,Zaidel DW

    更新日期:1994-08-01 00:00:00

  • Cerebral blood flow and neuropsychological functioning in elderly vascular disease patients.

    abstract::This study was designed to determine the relationships between positron emission tomography (PET)-based quantitative measures of cerebral blood flow and cerebrovascular reserve and neuropsychological functioning in elderly individuals with atherosclerotic vascular disease. It was hypothesized that cerebrovascular func...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803395.2011.630653

    authors: Moser DJ,Boles Ponto LL,Miller IN,Schultz SK,Menda Y,Arndt S,Nopoulos PC

    更新日期:2012-01-01 00:00:00

  • Persistent neuropsychological impairment associated with West Nile virus infection.

    abstract::West Nile virus infection can result in prolonged subjective complaints of cognitive and functional decline even in the absence of a neuroinvasive form of infection. Persistent cognitive and functional complaints could be a result of general somatic symptoms, emotional distress, or residual central nervous system dama...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803390902881918

    authors: Sadek JR,Pergam SA,Harrington JA,Echevarria LA,Davis LE,Goade D,Harnar J,Nofchissey RA,Sewell CM,Ettestad P,Haaland KY

    更新日期:2010-01-01 00:00:00

  • Postconcussion symptom reporting is not associated with diffusion tensor imaging findings in the subacute to chronic phase of recovery in military service members following mild traumatic brain injury.

    abstract:INTRODUCTION:The purpose of this study was to examine the relation between white matter integrity of the brain and postconcussion symptom reporting following mild traumatic brain injury (MTBI). METHOD:Participants were 109 U.S. military service members (91.7% male) who had sustained a MTBI (n = 88) or orthopedic injur...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803395.2019.1585518

    authors: Lange RT,Yeh PH,Brickell TA,Lippa SM,French LM

    更新日期:2019-07-01 00:00:00

  • Impaired decision-making under risk in patients with functional dyspepsia.

    abstract:INTRODUCTION:The cognitive processing in patients with functional dyspepsia (FD) has not been well established. Decision-making is an important component of cognitive function. Most brain regions involved in decision-making are abnormal in FD patients. This study aimed to investigate the decision-making under ambiguity...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/13803395.2020.1802406

    authors: Zhang S,Wu L,Zhang B,Zhu Y,Fan Y,Wang Q,Hu X,Tian Y

    更新日期:2020-10-01 00:00:00

  • Neuropsychological functioning of hydrocephalic children.

    abstract::A group of 30 five- to eight-year-old hydrocephalic children was administered a comprehensive battery of neuropsychological tests. As a group, they displayed a pattern of lower PIQ than VIQ. Their performance was within the average range of many neuropsychological tests, but they performed poorly on some measures of c...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/01688639108401075

    authors: Donders J,Rourke BP,Canady AI

    更新日期:1991-07-01 00:00:00

  • Cognitive impairments in HCV infection: From pathogenesis to neuroimaging.

    abstract::Extrahepatic manifestations of hepatitis C virus (HCV) infection, in particular cognitive impairments, can be present in the absence of clinical liver dysfunction. Executive memory, attention, and concentration are cognitive domains that are most frequently affected. Microstructural and functional changes in cortical ...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章,评审

    doi:10.1080/13803395.2019.1652728

    authors: Amirsardari Z,Rahmani F,Rezaei N

    更新日期:2019-12-01 00:00:00

  • Recovery from aphasia following extracranial-intracranial bypass surgery: case report.

    abstract::The Boston Diagnostic Aphasia Exam and brief measures of memory, stereognosis, and limb praxis were administered to an extracranial-intracranial bypass surgery patient with moderately severe transcortical aphasia preoperatively and postoperatively. Significant improvement in language function was documented 2 days fol...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/01688638508401255

    authors: Hart RP,Rosner MJ,Muizelaar P

    更新日期:1985-06-01 00:00:00

  • Presidents Test performance in varieties of diffuse and unilateral cerebral disease.

    abstract::Two studies addressed issues concerning the validity of the Presidents Test. The results of Study 1 substantiated that generalized impairment for recent presidents occurs frequently in the context of multifocal and diffuse cerebral disease. Performances of normal elderly (n = 31) on all four Presidents subtests were s...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 杂志文章

    doi:10.1080/01688639008400967

    authors: Roberts RJ,Hamsher KD,Bayless JD,Lee GP

    更新日期:1990-03-01 00:00:00

  • Prediction of psychosocial recovery after head injury with cognitive tests and neurobehavioral ratings.

    abstract::A series of 53 patients was studied using a battery of tests and a neurobehavioral rating scale on average 4 months after closed-head injury (CHI). Social outcome was assessed 1 year after injury by interviewing a family member. The results supported the hypothesis that tests of flexibility and programming rather than...

    journal_title:Journal of clinical and experimental neuropsychology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1080/01688639408402643

    authors: Vilkki J,Ahola K,Holst P,Ohman J,Servo A,Heiskanen O

    更新日期:1994-06-01 00:00:00