Abstract:
:Neuropsychological test performance and estimates of regional rates of cortical glucose metabolism obtained via positron emission tomography are presented for patients with Alzheimer's disease (AD). Analyses of these data indicated the presence of distinct subgroups characterized by qualitatively different profiles of cognitive impairment and corresponding patterns of cerebral hypometabolism. No subgroup differences were noted with regard to age at onset or reported duration of symptoms. These findings indicate that, in a given individual, AD may initially invade a relatively circumscribed cortical region. Thus, although AD may constitute a single disease process, it does not result in a unitary neuropsychological syndrome.
journal_name
J Clin Exp Neuropsycholjournal_title
Journal of clinical and experimental neuropsychologyauthors
Martin A,Brouwers P,Lalonde F,Cox C,Teleska P,Fedio P,Foster NL,Chase TNdoi
10.1080/01688638608405178subject
Has Abstractpub_date
1986-10-01 00:00:00pages
594-610issue
5eissn
1380-3395issn
1744-411Xjournal_volume
8pub_type
杂志文章abstract::Neurocognitive function is reduced in major depression, but uncertainties remain about if and to what extent improvement in neurocognitive function follows remission of depressive symptoms. A total of 30 patients with Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition (DSM-IV) diagnosis of unipolar m...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803390601147686
更新日期:2007-11-01 00:00:00
abstract::Depression and memory difficulties are among the most common complaints voiced by patients with multiple sclerosis (MS). Nevertheless, little is known about how depression might affect patients' perceptions of their memory difficulties. The present investigation was designed to explore this issue. Results supported a ...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1076/jcen.26.2.200.28081
更新日期:2004-04-01 00:00:00
abstract::Atrophy of specific, regional, and generalized brain structures occurs as a result of the Alzheimer's disease (AD) process. Comparing AD patients with histopathological confirmation of the disease at autopsy to those without autopsy but who were clinically diagnosed using the same antemortem criteria will provide furt...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803390600826579
更新日期:2007-07-01 00:00:00
abstract::Two groups of patients affected by mild dementia of the Alzheimer's type (n = 42) or by depressive pseudo-dementia (n = 26) were given a modified version of the Rey's Auditory Verbal Learning Test. The two groups were roughly matched for overall level of cognitive impairment. The main purpose of the research was to de...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/01688639408402617
更新日期:1994-02-01 00:00:00
abstract::Levels and rates of acquisition and amounts of forgetting of name-face associations and grocery list items were assessed in a sample of 1,921 normal participants that was divided into five age groups (i.e., 17-39, 40-49, 50-59, 60-69, and 70+). Retrieval was assessed via the consistent long-term retrieval score (CLTR)...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/01688639308402570
更新日期:1993-07-01 00:00:00
abstract::Persons who have the genetic mutation responsible for Huntington's disease (HD) have been shown to exhibit lower cognitive test scores years prior to manifest HD. Most studies have examined cognitive performance in presymptomatic persons by using estimated times to manifest HD based on published algorithms. We followe...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2011.574606
更新日期:2011-10-01 00:00:00
abstract::Decline in memory function was detected in 30% of healthy community-dwelling elderly over 6 years using a task assessing delayed word list recall. Individuals with memory decline over time also demonstrated relative deficits on additional tasks of memory and learning, a task of working memory and executive function, a...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13825580600954256
更新日期:2007-10-01 00:00:00
abstract::Recovery in 60 patients with a closed-head injury (CHI) in the first year posttrauma was assessed repeatedly with a series of attention tests. A matched group of healthy subjects was tested at the same intervals to allow us to control for practice effects. The results of a multilevel analysis for longitudinal data sho...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1076/jcen.21.5.585.874
更新日期:1999-10-01 00:00:00
abstract:OBJECTIVE:The objective was to determine whether neuropsychological tests provide an equivalent measure of the same psychological constructs in older adults with low versus higher levels of education. METHOD:Confirmatory factor analysis was used to evaluate the fit of a three-factor model (Verbal Ability, Visuospatial...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2014.967661
更新日期:2014-01-01 00:00:00
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journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2012.670209
更新日期:2012-01-01 00:00:00
abstract::Reconstructing the temporal order of events is a crucial part of episodic memory. The temporal dimension, however, is often discarded in clinical settings, and measurements of true temporal aspects of episodic memory are scarce. The present study assessed temporal memory in stroke patients and in age- and education-ma...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2014.925093
更新日期:2014-01-01 00:00:00
abstract:INTRODUCTION:Our study investigated the ability of nondemented Parkinson's disease (PD) patients to explicitly identify emotional words and to show implicit sensitivity to these emotions in a task that did not require emotional processing. METHODS:Twelve PD patients and 12 healthy controls, matched for age and educati...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2011.639296
更新日期:2012-01-01 00:00:00
abstract::To evaluate the construct and predictive validity of a brief neuropsychological assessment battery, consecutive admissions to a hospital receiving inpatient treatment for stroke were tested with the Repeatable Battery for Assessment of Neuropsychological Status (RBANS) and other neuropsychological measures. Discrimina...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/138033990513564
更新日期:2005-01-01 00:00:00
abstract::Recent research suggests that effort detection measures based on patterns of neuropsychological performance may be more robust to coaching than traditional effort detection measures. In the present study, we evaluated the Exaggeration Index for an extended version of the Auditory Verbal Learning Test (EI-AVLTX), a rec...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803390490510121
更新日期:2004-05-01 00:00:00
abstract:INTRODUCTION:The Rey Complex Figure Test (RCFT) is a popular measure of visuospatial and executive functioning. Clinical interpretations of RCFT performance are partly based on how an individual approaches the task with piecemeal organization often considered indicative of impairment. This is despite little previous re...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2015.1075473
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:Self-perceived mental fatigue is a common presenting symptom in many neurological diseases. Discriminating objective fatigability from self-perceived mental fatigue might facilitate neuropsychological diagnosis and treatment programs. However clinically valid neuropsychological instruments suitable for assess...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2014.933779
更新日期:2014-01-01 00:00:00
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journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2012.690368
更新日期:2012-01-01 00:00:00
abstract::Abbreviated versions of the Wechsler Adult Intelligence Scale-Revised (WAIS-R) have been developed as time saving devices that provide accurate estimates of overall level of general intellectual functioning while decreasing test administration time. The Satz-Mogel short form of the WAIS-R has received substantial atte...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1076/1380-3395(200010)22:5;1-9;FT545
更新日期:2000-10-01 00:00:00
abstract::Participants scoring high and low on a schizotypy scale (n=18 in each group) switched between naming words and naming colors in a Stroop task in congruent, neutral, and incongruent conditions. The findings were that, while being slower and less accurate overall than low schizotypes, the high schizotypy group did not d...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803390701336866
更新日期:2008-02-01 00:00:00
abstract:INTRODUCTION:There have been suggestions of hypofrontality in cannabis users. To understand cannabis-related differences in decisional processes, Janis and Mann's conflict model of decision making was applied to recreational cannabis smokers who varied in their alcohol use and level of psychological distress. METHOD:A...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2016.1255311
更新日期:2017-09-01 00:00:00
abstract::Memory for pairs of unfamiliar children's faces was investigated in 29 children and adolescents suffering from left (LTLE) or right (RTLE) temporal-lobe epilepsy, before and after temporal-lobe surgery. Both immediate and delayed memory were tested. Before surgery, RTLE subjects performed worse than either LTLE subjec...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/01688639408402670
更新日期:1994-08-01 00:00:00
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journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2011.630653
更新日期:2012-01-01 00:00:00
abstract::West Nile virus infection can result in prolonged subjective complaints of cognitive and functional decline even in the absence of a neuroinvasive form of infection. Persistent cognitive and functional complaints could be a result of general somatic symptoms, emotional distress, or residual central nervous system dama...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803390902881918
更新日期:2010-01-01 00:00:00
abstract:INTRODUCTION:The purpose of this study was to examine the relation between white matter integrity of the brain and postconcussion symptom reporting following mild traumatic brain injury (MTBI). METHOD:Participants were 109 U.S. military service members (91.7% male) who had sustained a MTBI (n = 88) or orthopedic injur...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2019.1585518
更新日期:2019-07-01 00:00:00
abstract:INTRODUCTION:The cognitive processing in patients with functional dyspepsia (FD) has not been well established. Decision-making is an important component of cognitive function. Most brain regions involved in decision-making are abnormal in FD patients. This study aimed to investigate the decision-making under ambiguity...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/13803395.2020.1802406
更新日期:2020-10-01 00:00:00
abstract::A group of 30 five- to eight-year-old hydrocephalic children was administered a comprehensive battery of neuropsychological tests. As a group, they displayed a pattern of lower PIQ than VIQ. Their performance was within the average range of many neuropsychological tests, but they performed poorly on some measures of c...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/01688639108401075
更新日期:1991-07-01 00:00:00
abstract::Extrahepatic manifestations of hepatitis C virus (HCV) infection, in particular cognitive impairments, can be present in the absence of clinical liver dysfunction. Executive memory, attention, and concentration are cognitive domains that are most frequently affected. Microstructural and functional changes in cortical ...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章,评审
doi:10.1080/13803395.2019.1652728
更新日期:2019-12-01 00:00:00
abstract::The Boston Diagnostic Aphasia Exam and brief measures of memory, stereognosis, and limb praxis were administered to an extracranial-intracranial bypass surgery patient with moderately severe transcortical aphasia preoperatively and postoperatively. Significant improvement in language function was documented 2 days fol...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
doi:10.1080/01688638508401255
更新日期:1985-06-01 00:00:00
abstract::Two studies addressed issues concerning the validity of the Presidents Test. The results of Study 1 substantiated that generalized impairment for recent presidents occurs frequently in the context of multifocal and diffuse cerebral disease. Performances of normal elderly (n = 31) on all four Presidents subtests were s...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 杂志文章
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更新日期:1990-03-01 00:00:00
abstract::A series of 53 patients was studied using a battery of tests and a neurobehavioral rating scale on average 4 months after closed-head injury (CHI). Social outcome was assessed 1 year after injury by interviewing a family member. The results supported the hypothesis that tests of flexibility and programming rather than...
journal_title:Journal of clinical and experimental neuropsychology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1080/01688639408402643
更新日期:1994-06-01 00:00:00