First hydroxamate inhibitors for carboxypeptidase A. N-acyl-N-hydroxy-beta-phenylalanines.

Abstract:

:A series of N-acyl-N-hydroxy-beta-Phe were designed, synthesized, and shown to have potent inhibitory activity for carboxypeptidase A (CPA). They are the first examples of CPA inhibitors having a hydroxamate functionality.

journal_name

Bioorg Med Chem Lett

authors

Kim DH,Jin Y

doi

10.1016/s0960-894x(99)00055-4

subject

Has Abstract

pub_date

1999-03-08 00:00:00

pages

691-6

issue

5

eissn

0960-894X

issn

1464-3405

pii

S0960894X99000554

journal_volume

9

pub_type

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