Abstract：
:MCA44 is a monoclonal antibody (mAb) to guinea-pig decay-accelerating factor (DAF) and, using this mAb, tissue distribution of guinea-pig DAF was studied by immunofluorescence. Guinea-pig DAF was found to be expressed not only on the vascular endothelium but also on different types of cells, such as the tubular epithelium of the kidney, epidermal cells of the skin and synovial lining cells. As there was no significant reduction in staining intensity with MCA44 following treatment with phosphatidylinositol-specific phospholipase C, many guinea-pig DAF molecules expressed in these tissues may be of the transmembrane form.
journal_name
Immunologyjournal_title
Immunologyauthors
Nishikawa K,Matsuo S,Tamai H,Okada N,Okada Hdoi
10.1046/j.1365-2567.1998.00592.xsubject
Has Abstractpub_date
1998-10-01 00:00:00pages
302-7issue
2eissn
0019-2805issn
1365-2567journal_volume
95pub_type
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