Abstract：
OBJECTIVE:To know the prevalence of adrenal insufficiency (AI) in our patients with acquired immunodeficiency syndrome (AIDS) and to compare the clinical manifestations with those reported in previous series in the literature. PATIENTS AND METHODS:Retrospective study with review of clinical records of patients with AIDS diagnosed of AI (plasma cortisol after synthetic ACTH < 18 micrograms/dl) in our hospital for a period of 6 and a half years. RESULTS:Eleven out of 65 patients (17%) with the hormonal study performed were diagnosed of AI. The prevalence of AI in our patients with AIDS was 1.66%. The response of plasma cortisol to synthetic ACTH was abnormal in the 11 patients (mean increase: 1.89 micrograms/dl). Nine out of the 11 patients had a decreased basal plasma cortisol level (mean: 4.75 micrograms/dl). Basal plasma ACTH levels were increased (mean: 638.9 pg/ml) in seven out of nine patients. Patients were severely immunosuppressed (mean CD4: 21/microliter). While the clinical course was subacute (mean: 5.1 weeks), nine out of the eleven patients developed an adrenal crisis which required emergency therapy. Ten patients had an opportunist infection--M. tuberculosis (3), M. avium-intracellulare (3), Cytomegalovirus (3), histoplasmosis (1)--which could involve the adrenal glands in ten patients. All patients responded to treatment but their mean survival was 5.6 weeks. CONCLUSIONS:Although the prevalence of AI in our patients with AIDS was low (1.66%), it is important to be aware of the disease and to order a basal plasma cortisol value after synthetic ACTH, as treatment improves the life quality of patients if AI is confirmed, despite a short survival time.
journal_name
Rev Clin Espjournal_title
Revista clinica espanolaauthors
Baraia-Etxaburu Artetxe J,Astigarraga Aguirre B,Elorza Olabegova R,Teira Cobo R,Yoldi Arrieta A,Cisterna Cancer R,Bustamante Murga V,Santamaría Jauregui JMsubject
Has Abstractpub_date
1998-02-01 00:00:00pages
74-9issue
2eissn
0014-2565issn
1578-1860journal_volume
198pub_type
杂志文章abstract：OBJECTIVES:Celiac disease is a chronic immune-mediated disease of the small intestine. It has been known that dilated cardiomyopathy and ischemic coronary artery disease have become more frequent in patients with celiac disease. The aim of the study was to assess Tp-e interval and Tp-e/QT ratio in patients with celiac ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2017.09.001
更新日期：2017-11-01 00:00:00
abstract：OBJECTIVE:Several studies have reported that a higher degree of hemoconcentration in patients admitted for the treatment of acute heart failure (HF) constitutes a favorable prognostic factor in the year following the index episode. The objective of this study was to evaluate whether the highest degree of hemoconcentrat...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2018.07.003
更新日期：2019-01-01 00:00:00
abstract：:In this clinical observation, we make a small summary of the current state of pharmacological treatment of obesity. The interest in the use of drugs in the treatment of obesity has grown in recent years, upon our knowledge of the biological basis of obesity having increased, and also because non-pharmacological treatm...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13074165
更新日期：2005-04-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:The aging population is resulting in an increasing number of patients with multiple diseases that require treatment by various specialties. We examined the evolution of consultations and of the percentage of patients treated by several medical specialties. METHODS:We analysed internal medicine...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2019.03.005
更新日期：2019-12-01 00:00:00
abstract：:The clinical features of 30 patients with carcinomatous meningitis caused by solid tumors are reported. The most common originating sites of tumors were lung (12 cases) and breast (9 cases). Headache was the most common presenting symptom and there was involvement in more than one level of neuro-axis in 53% of cases. ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1994-07-01 00:00:00
abstract：:Non insulin antidiabetic drugs are widely used in patients with type 2 diabetes. However, the drugs' effect in terms of reducing cardiovascular risk has been the subject of controversy. In 2008, based on the evidence of cardiovascular risk resulting from the use of a number of non insulin antidiabetic drugs, the US Fo...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2017.02.007
更新日期：2017-11-01 00:00:00
abstract：OBJECTIVE:To identify factors associated with poor anticoagulation control with vitaminK antagonists (VKA) among outpatients with nonvalvular atrial fibrillation (NVAF) attended in Neurology and Internal Medicine in Spain. METHODS:Cross-sectional and multicenter study, from the ALADIN database, of outpatients with NVA...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2018.04.020
更新日期：2018-10-01 00:00:00
abstract：:In order to assess factors associated with spontaneous pneumothorax (SP), mainly climatic changes, a prospective study was undertaken of 62 SP episodes among patients admitted to our hospital during a two-year period, from January 1994 to January 1996. Atmospheric pressure (AP) changes were analyzed, with daily record...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(02)70990-9
更新日期：2002-02-01 00:00:00
abstract：:Pneumonia due to Pneumocystis carinii (PC) is characterized, in most cases, by the existence of infiltrates of interstitium or bilateral interstitium-alveolar type on the thorax radiography. However atypical radiological findings associated with this type of opportunistic infection are being described more and more fr...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1992-09-01 00:00:00
abstract：BACKGROUND:The increase in intraabdominal pressure (IAP) has been correlated with increased creatinine levels in patients with heart failure with severely reduced left ventricular ejection fraction (HFrEF). However, IAP has not been examined in more stable patients or those with heart failure with preserved ejection fr...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2020.01.011
更新日期：2020-07-09 00:00:00
abstract：:The epithelial neoplasias associated to monoclonal gammapathy (GM) seen in a general hospital over a period of six years are reviewed. 8 cases were detected, 2 of which behaved as a second neoplasia since they occurred in patients previously diagnosed of multiple myeloma. The incidence and characteristics of the monoc...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1989-10-01 00:00:00
abstract：:Toxic shock syndrome (TSS) is a potentially fatal acute disease preferentially affecting menstruating women and is related to the use of vaginal tampons seems to be due to an specific exotoxin produced by some Staphylococcus aureus strains. We present here the case of a male patients suffering cavitated pneumonia who ...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：
更新日期：1990-05-01 00:00:00
abstract：:A case report of severe digitalis poisoning in a patient with prosthetic heart valve is presented. He complained of nausea, vomiting, drowsiness, temporal disorientation and lethargy. The electrocardiogram showed idioventricular rhythm, and plasma levels of digoxin were 6.78 ng/ml. Predisposing factors por digitalis p...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1991-11-01 00:00:00
abstract：OBJECTIVE:To know the characteristics of nocardiosis in HIV infected patients. PATIENTS AND METHODS:Retrospective analysis of HIV infected patients with a concomitant Nocardia spp. infection in nine Andalusian hospitals. RESULTS:Eighteen cases of nocardiosis were studied. Seventeen patients were males and the mean ag...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(02)71084-9
更新日期：2002-07-01 00:00:00
abstract：:This review proposes a more optimistic view of Alzheimer's disease (AD), in contrast to that contributed by the ageing of the population and the failure of potentially curative therapies (vaccines and others). Treatment failure is likely due to the fact that AD gestates in the brain for decades but manifests in old ag...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2016.05.010
更新日期：2016-12-01 00:00:00
abstract：OBJECTIVE:To determine the primary drug resistance (PDR) of Mycobacterium tuberculosis in ten hospitals in the Castile-León Community for a five-year period (1991-1995), in a sanitary area with almost two millions of inhabitants. MATERIAL AND METHODS:The sensitivity of 825 strains of Mycobacterium tuberculosis to anti...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1999-03-01 00:00:00
abstract：:Sarcoidosis is a disease which presents important clinical differences according to its geographical distribution. Thus, the objective of this study was to evaluate the epidemiologic, clinical, radiologic, and diagnostic characteristics in a series of 30 sarcoidosis patients in the province of Salamanca (representing ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1991-09-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Oral anticoagulant therapy is complex due to the need for control and the hemorrhagic risk the therapy entails. This study aims to determine the standard clinical practice in the treatment for preventing stroke in patients with nonvalvular atrial fibrillation (NVAF) in Spain. PATIENTS AND MET...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2014.08.008
更新日期：2015-03-01 00:00:00
abstract：OBJECTIVE:To describe the incidence and characteristics of the infection caused by Mycobacterium tuberculosis in patients with autoimmune diseases. PATIENTS AND METHODS:Searching in the database of the department at our institution, all new cases of tuberculosis from 1991 to 2000 were identified in patients with autoi...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13045537
更新日期：2003-04-01 00:00:00
abstract：OBJECTIVE:Analyze whether the tablets available in Spain are useful for oral replacement in the treatment of vitamin B12 deficiency. METHODS:From June 2003 to December 2005, patients with vitamin B12 deficiency attended at the Internal Medicine Clinic, were offered the possibility of starting or switching to oral ther...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13101846
更新日期：2007-04-01 00:00:00
abstract：BACKGROUND:Description of the patients admitted in the general Internal Medicine (IM) departments of the Public Health System in Andalusia (Spain) (PHSA) during 2002. PATIENTS AND METHODS:It is an analysis of the Minimum Basic Set of Data (MBSD) and its management by the Diagnostic Related Groups (DRG) of admission ep...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13084760
更新日期：2006-01-01 00:00:00
abstract：:The antibiotherapy resistance evolution and the appearance of new enterobacter in our ICU's flora have been studied. A total of 638 bacterial samples were studied. The most frequent isolated pathogens were: Pseudomonas aeruginosa (182 strands), Escherichia coli (108 strands), Staphylococcus epidermidis (99 strands) an...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1990-04-01 00:00:00
abstract：:Cancer of unknown primary site (CUPS) is a heterogeneous entity defined by the presence of a histologically-proven metastatic neoplasm, in which the original tumor cannot be identified after a targeted study. The current guidelines for CUPS focus is not based on the search for the primary neoplasm but rather on the id...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(09)71820-x
更新日期：2009-07-01 00:00:00
abstract：OBJECTIVES:To analyze the effect of a global approach on patients with high cardiovascular risk for the integral control of cardiovascular risk factors. PATIENTS AND METHODS:Multicentric prospective study of patients with high vascular risk, followed-up for one year in internal medicine consultations. We measured the ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13100222
更新日期：2007-03-01 00:00:00
abstract：OBJECTIVES:To evaluate the independent usefulness of pleural fluid smear and cell block (CB) preparations for the diagnosis of malignant effusions. PATIENTS AND METHODS:A total of 632 cytological smears and 554 CBs from 414 consecutive patients with malignant effusions were retrospectively evaluated. RESULTS:The diag...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2016.11.004
更新日期：2017-04-01 00:00:00
abstract：OBJECTIVES:To evaluate the scientific output in Biomedicine and Health Sciences in Andalusia in the context of the published works on the national scientific output in the last few years. MATERIAL:Descriptive study with seven different information sources: a) final Report of the Experts Committee on Documentation from...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：:The proportion of diabetic patients who are hospitalised for stroke has been increasing in recent years, currently reaching almost a third of all cases of stroke. In addition, about half of patients with acute stroke present hyperglycaemia in the first hours of the stroke. Although hyperglycaemia in the acute phase of...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2015.06.005
更新日期：2016-03-01 00:00:00
abstract：OBJECTIVE:To study the prevalence of hepatitis delta and hepatitis C viruses (HDV and HCV) in patients infected with hepatitis B virus (HBV) with and without risk behaviors for the infection by these viruses and by the human immunodeficiency virus (HIV). MATERIALS AND METHODS:Clinical and serological study (January 19...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1994-10-01 00:00:00
abstract：INTRODUCTION:Pyrosis symptoms and their impact on the quality of life related with health (QLRH) are frequently evaluated in clinical trials. When a questionnaire is translated into a language other than the original, it is necessary to have a linguistic validation, although this is not sufficient unless the psychometr...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(05)72651-5
更新日期：2005-12-01 00:00:00
abstract：OBJECTIVE:Analyze the effect of AM3, an oral immunomodulator, on the exacerbations and on the use of antibiotics in patients with chronic obstructive pulmonary disease (COPD). DESIGN:Systematic search of controlled clinical trials that used AM3 in some treatment group and that included data on the clinical effects of ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13065976
更新日期：2004-09-01 00:00:00
