Abstract：
:This review proposes a more optimistic view of Alzheimer's disease (AD), in contrast to that contributed by the ageing of the population and the failure of potentially curative therapies (vaccines and others). Treatment failure is likely due to the fact that AD gestates in the brain for decades but manifests in old age. This review updates the concept of AD and presents the results of recent studies that show that primary prevention can reduce the incidence and delay the onset of the disease. Half of all cases of AD are potentially preventable through education, the control of cardiovascular risk factors, the promotion of healthy lifestyles and specific drug treatments. These approaches could substantially reduce the future incidence rate of this disease.
journal_name
Rev Clin Espjournal_title
Revista clinica espanolaauthors
Bermejo-Pareja F,Llamas-Velasco S,Villarejo-Galende Adoi
10.1016/j.rce.2016.05.010subject
Has Abstractpub_date
2016-12-01 00:00:00pages
495-503issue
9eissn
0014-2565issn
1578-1860pii
S0014-2565(16)30083-2journal_volume
216pub_type
杂志文章abstract：:The validity of estimates of energy intake in a group of young women, and the influence of body mass index (BMI) and concern over bodyweight on such estimates, were determined with the aid of a food record intake. The study subjects were a group of female university students between 20 and 32 years of age. Participant...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1997-08-01 00:00:00
abstract：OBJECTIVE:Several studies have reported that a higher degree of hemoconcentration in patients admitted for the treatment of acute heart failure (HF) constitutes a favorable prognostic factor in the year following the index episode. The objective of this study was to evaluate whether the highest degree of hemoconcentrat...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2018.07.003
更新日期：2019-01-01 00:00:00
abstract：:Three new cases of diffuse pulmonary lymphangioleiomyomatosis are presented. Case number 1 is a female patient who presented repeated pneumotorax and dyspnea without evidence by CT scan and gynecological ultrasound of extrathoracic lesions. This patient did not respond to medroxiprogesterone and died 5 years after the...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：
更新日期：1990-04-01 00:00:00
abstract：:Central nervous system compromise is a major cause of morbidity and mortality in SLE. The clinical picture of cerebral cryptococcosis is non-specific and can be mistaken for lupic activity. A retrospective study was undertaken with 10 patients with SLE and cryptococcal meningitis compiled in a 23-year period. The most...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：OBJECTIVES:We evaluated the effect of an intervention on certain quality indicators employed for improving the treatment of hospital hyperglycemia. MATERIAL AND METHODS:A multicenter cross-sectional study was conducted on patients with hyperglycemia hospitalized in the internal medicine departments of 44 hospitals eva...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2016.05.006
更新日期：2016-10-01 00:00:00
abstract：:After recognizing smoking habit as a relevant problem in our media, the complex implications of this type of lifestyle are commented. After revising the main obstacles for achieving primary health care preventive measures not only for the patient, who frequently looks for a "treatment", but also for the professional w...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：
更新日期：1989-03-01 00:00:00
abstract：OBJECTIVE:To determine the primary drug resistance (PDR) of Mycobacterium tuberculosis in ten hospitals in the Castile-León Community for a five-year period (1991-1995), in a sanitary area with almost two millions of inhabitants. MATERIAL AND METHODS:The sensitivity of 825 strains of Mycobacterium tuberculosis to anti...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1999-03-01 00:00:00
abstract：:In order to know the epidemiological, clinical and evolutive characteristics of bacteriemia caused by beta-hemolytic streptococci groups A and B, a retrospective investigation was undertaken of 48 bacteremic episodes observed in adult patients for 10 years (1985-1994). Twenty-two episodes were caused by Group A beta-h...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1995-08-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Atrial fibrillation (AF) is the most common type of arrhythmia. The purpose of this study was to determine the prevalence of atrial fibrillation and its relationship with cardiovascular risk factors in Spain. METHODOLOGY:Cross-sectional study based on a grouped analysis of 17,291 randomized i...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2014.06.006
更新日期：2014-12-01 00:00:00
abstract：:Acute renal insufficiency associated to cocaine consumption is well known, and normally secondary to rhabdomyolisis. The possibility that renal failure is related to hypertension and to renal histopathological findings indistinguishable of other malignant hypertension conditions is a not as well known fact. Certain de...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13060272
更新日期：2004-04-01 00:00:00
abstract：:Pseudohypoparathyroidism is a rare disease characterized by a target tissue resistance to the action of the parathyroid hormone (PTH). Frequently, others hormonal disorders can be associated. We report a family with pseudohypoparathyroidism type I, and discuss the clinical-hormonal alterations founded; it is emphasize...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1993-09-01 00:00:00
abstract：BACKGROUND:In recent years, there has been an increase of drugs poisoning cases seen in the Emergency Department. This study has aimed to evaluate the characteristics of these cases in the Ramón and Cajal Hospital in Madrid. MATERIALS AND METHODS:A descriptive analysis about the drug poisonings diagnosed in 2004 was p...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13127603
更新日期：2008-10-01 00:00:00
abstract：INTRODUCTION:Geographic tongue (GT) is a lesion of unknown origin associated with systemic diseases and therefore involves multidisciplinary care. METHODS:We performed a literature search of the PubMed, EMBASE, Web of Science and Cochrane databases. The selection criteria were consistent with the Preferred Reporting I...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：10.1016/j.rce.2018.05.006
更新日期：2018-12-01 00:00:00
abstract：OBJECTIVE:The objective of this study was to determine the prognostic factors in relationship to evolution to death of bacteremia-fungemia (BF) episodes occurred in 1986 and to compare them with the results obtained ten years later in 1996. PATIENTS AND METHODS:Prospective study of all BF episodes observed at Hospital...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(01)70765-5
更新日期：2001-03-01 00:00:00
abstract：OBJECTIVE:To determine the appearance of type 2 diabetes mellitus (DM2) and impaired fasting glucose (IFG) at five years of follow-up in a known non-diabetic population. PATIENTS AND METHODS: DESIGN:nested case control studies (case s-control into a cohort) developed in two stages: 1) identification and characterizat...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(09)70351-0
更新日期：2009-01-01 00:00:00
abstract：BACKGROUND:Description of the patients admitted in the general Internal Medicine (IM) departments of the Public Health System in Andalusia (Spain) (PHSA) during 2002. PATIENTS AND METHODS:It is an analysis of the Minimum Basic Set of Data (MBSD) and its management by the Diagnostic Related Groups (DRG) of admission ep...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13084760
更新日期：2006-01-01 00:00:00
abstract：OBJECTIVES:Celiac disease is a chronic immune-mediated disease of the small intestine. It has been known that dilated cardiomyopathy and ischemic coronary artery disease have become more frequent in patients with celiac disease. The aim of the study was to assess Tp-e interval and Tp-e/QT ratio in patients with celiac ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2017.09.001
更新日期：2017-11-01 00:00:00
abstract：:The understanding of the causes for hyperamylasemia is of great importance when focusing on the differential diagnosis of acute pancreatitis. Among the causes for hyperamylasemia, special interest is given to macroamylasemia not only because it is poorly understood, but also because we are lacking national studies. In...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：
更新日期：1989-05-01 00:00:00
abstract：:Antibodies (type IgG) against the A 60 antigen (Mycobacterium bovis, BCG) and an antigen of Mycobacterium tuberculosis were studied by ELISA in 79 patients with not tuberculous disease: 16 lung carcinoma, 16 hepatic cirrhosis and 47 patients with pulmonary disease. 59.5% and 50.6% of the patients showed antibodies aga...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
abstract：:Our objective has been to elaborate an updated Clinical Guide of the Spanish Society of Internal Medicine (SEMI) for the prevention and treatment of glucocorticoids-induced osteoporosis (GIO), identifying and measuring the grade of evidence that supports the given recommendations. For this, we reviewed studies perform...
journal_title：Revista clinica espanola
pub_type： 杂志文章,实务指引
doi：10.1157/13115006
更新日期：2008-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:The pleural fluid/serum cholinesterase ratio (PF/S) is the most efficient parameter to differentiate transudates from exudates. The objective of this study was to evaluate whether its determination might yield additional diagnostic information in pleural exudates. MATERIALS AND METHODS:A tota...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1997-06-01 00:00:00
abstract：:Fibromyalgia or fibromyalgic syndrome (FMS) is a clinical picture of unknown origin that is characterized by generalized, incapacitating and chronic pain together with the demonstration in the physical examination of previously defined points in which moderate pressure causes pain, called fibromyalgia tender points (F...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13077119
更新日期：2005-07-01 00:00:00
abstract：BACKGROUND:Sarcopenia is characterized by the loss of skeletal muscle mass and strength and represents a risk factor for frailty, loss of independence and physical disabilities. This study aimed to assess the prevalence of sarcopenia in a population of patients admitted to a media and long-stay unit. PATIENTS AND METH...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2014.02.018
更新日期：2014-08-01 00:00:00
abstract：:Coeliac disease is the most frequent malabsortive syndrome in daily practice. However, its true prevalence is not exactly known. The symptoms vary from patient to patient, ranging from the classic presentation with diarrhea, weight loss and fatigue to oligosymptomatic forms, being the latter more common in adults. We ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1996-01-01 00:00:00
abstract：:For patients to be able to make decisions autonomously (and to grant informed consent), they must have information, understanding, freedom and willingness, with competence a prerequisite for autonomy. Clinicians are often faced with patients lacking competence to make decisions but detect less than half of such cases ...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：10.1016/j.rce.2019.04.009
更新日期：2020-05-01 00:00:00
abstract：:The purpose of this study was to review the epidemiological aspects and the characteristics of the thyroid disfunction produced by amiodarone in Catalonia, an area with type I endemic goiter. For this purpose, three groups of patients have been studied: 1) 102 patients with prolonged amiodarone treatment, out of whom ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1991-02-01 00:00:00
abstract：:Pancreas transplantation offers the possibility of preventing the development and progression of diabetic lesions by adequate control of hydrocarbon metabolism. Moreover, the diabetic patient is freed from dietary and physical restrictions, as well as from insulin treatment. However, this is achieved at the expense of...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：
更新日期：1989-07-01 00:00:00
abstract：:Laughter is associated to many physiological and psychological benefits. Although women laugh more than men do, the daily frequency of laughter does not seem to differ. Laughter in all its forms and manifestations is an indicator of family vitality and healthy couples. Laughter is very attractive at the interpersonal ...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：10.1016/j.rce.2010.10.013
更新日期：2011-07-01 00:00:00
abstract：BACKGROUND:There are no simple and validated instruments for evaluating the training of specialists. OBJECTIVES:To analyze the reliability and validity of a computerized self-assessment method to quantify the acquisition of medical competences during the Internal Medicine residency program. METHODS:All residents of o...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2012.04.004
更新日期：2012-12-01 00:00:00
abstract：:To establish the possible relationship between acute myocardial infarction (AMI) and dehydroepiandrosterone-sulfate (DHEA-S) in a group of 15 patients with AMI, blood levels of DHEA-S and certain lipids (total cholesterol, LDL-cholesterol, HDL-cholesterol and triglycerides) were determined at admission in the hospital...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
