Abstract：
OBJECTIVE:To determine the appearance of type 2 diabetes mellitus (DM2) and impaired fasting glucose (IFG) at five years of follow-up in a known non-diabetic population. PATIENTS AND METHODS: DESIGN:nested case control studies (case s-control into a cohort) developed in two stages: 1) identification and characterization of the cohort and 2) follow-up. STUDY POPULATION:representative sample of a non-diabetic population between 40 and 75 years old attended in a Primary Health Center. RESULTS: IDENTIFICATION:326 persons, 2.1% of whom were diagnosed of previously unknown DM2 and 7.3% of IFG. Insulin resistance (IR) was higher in patients with IFG and pancreatic function of beta cells (PFBC) was higher in the population without glucose metabolism alteration. FOLLOW-UP:121 persons, 9.7 % of whom evolved to DM2 (all with IFG). IFG proportion at the end of the follow-up was 23.96%. CONCLUSIONS:At 5 years of follow-up, more than 1/3 of the population studied developed DM2 or IFG. These diagnoses were related with IR and PFBC.
journal_name
Rev Clin Espjournal_title
Revista clinica espanolaauthors
Vernet Vernet M,Sender Palacios MJ,Jovell Fernández E,Casals Riera R,Tor Figueras E,Anglada Barceló Jdoi
10.1016/s0014-2565(09)70351-0subject
Has Abstractpub_date
2009-01-01 00:00:00pages
3-8issue
1eissn
0014-2565issn
1578-1860pii
S0014-2565(09)70351-0journal_volume
209pub_type
杂志文章abstract：:Clinical findings and response to treatment in four cases with plasma cell leukemia (PCL) out of 152 patients of multiple myeloma diagnosed at the Hospital La Paz from 1969 to 1988 are studied. Three of the four plasma cell leukemia cases presented a primary form, and one a secondary form. Our cases had a lower incide...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1991-11-01 00:00:00
abstract：OBJECTIVE:To analyze the different therapeutic attitudes towards patients with arterial hypertension (AH) or white coat hypertension (WCH). DESIGN:Longitudinal, retrospective study after performing a 24 h ambulatory blood pressure monitoring of ABPM. SETTING:Urban health center. PATIENTS:Eighty-six patients aged ove...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：2001-04-01 00:00:00
abstract：:The clinical features of 30 patients with carcinomatous meningitis caused by solid tumors are reported. The most common originating sites of tumors were lung (12 cases) and breast (9 cases). Headache was the most common presenting symptom and there was involvement in more than one level of neuro-axis in 53% of cases. ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1994-07-01 00:00:00
abstract：:Type 2 diabetes mellitus is a major health problem with high prevalence, morbidity and mortality, and its medical treatment is growing in complexity due to patients' diverse clinical conditions. This article presents a consensus document by the Diabetes, Obesity and Nutrition Group of the Spanish Society of Internal M...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2020.06.005
更新日期：2020-07-13 00:00:00
abstract：:Knowledge of cardiovascular disease is advancing at a vertiginous pace. Cardiology has always been one of the most scientifically dynamic specialties. Indeed, no other medical specialty presents such a large number of randomized studies aiming to determine the efficacy of distinct therapeutic interventions each year. ...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：10.1016/S0014-2565(10)70002-3
更新日期：2010-09-01 00:00:00
abstract：:Patobiographic data of four brilliant painters who lived in three different centuries (Goya [XVIII], Fortuny and Van Gogh [XIX] and Portinari [XX]), were examined in search for a suspected lead poisoning. It is concluded that Goya's disease and deafness was probably caused by lead poisoning. Fortuny's death was probab...
journal_title：Revista clinica espanola
pub_type： 传,历史文章,杂志文章
doi：10.1016/s0014-2565(06)72707-2
更新日期：2006-01-01 00:00:00
abstract：BACKGROUND:In the last few years, Strongyloides stercoralis has been repeatedly recovered from indigenous farmers in the Safor area (Valencia Community). The relationship between the different occupational activities, mainly farming, and the presence of strongyloidiasis was investigated. PATIENTS AND METHODS:A paired ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(01)70755-2
更新日期：2001-02-01 00:00:00
abstract：BACKGROUND:High concentrations of total and LDL-cholesterol and low concentrations of HDL-cholesterol are related to morbidity and mortality due to cardiovascular diseases. In this study, lipid concentration, prevalence of hypercholesterolemia and the association between hypercholesterolemia and other cardiovascular ri...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1993-06-01 00:00:00
abstract：:The increase in the incidence of tuberculosis infection in the last few years has caused a recurrence of atypical clinical forms, as well as the development of associations and uncommon complications during the clinical course, which include the adult respiratory distress syndrome (ARDS) and septic shock. Three patien...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1995-03-01 00:00:00
abstract：:Two cases are reported of women aged 18 and 36 years respectively who developed a typical picture of hyperthyroidism by Graves Basedow disease (primary hyperthyroidism, diffuse goiter with increased uptake, positive stimulating thyroid antibodies, exophthalmos). These women had taken drugs for obesity which were prepa...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1996-08-01 00:00:00
abstract：:255 patients diagnosed of pulmonary and/or pleural tuberculosis are prospectively studied. All patients received four drugs: isoniazine (INH), rifampin, pirazinamide and ethambutol during the first two months of treatment. Afterwards they continued for four months with two drugs in order to complete the six month trea...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1990-02-01 00:00:00
abstract：:Clinical ultrasonography should be considered a complementary examination that can change clinical practice, as well as a tool to add to the medical history. Systemic autoimmune diseases (SAD) can involve numerous structures and organs. Ultrasonography has broad applied utility in detecting complications such as the p...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2019.07.014
更新日期：2020-01-01 00:00:00
abstract：:Painful legs and moving toes syndrome is a rare medical picture characterized by involuntary movements of the toes or the whole foot and pain in lower limbs. However, this must be kept in mind due to its association with other diseases and its possibility of being the first symptom. Spinal cord and cauda equina diseas...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：10.1157/13102318
更新日期：2007-05-01 00:00:00
abstract：:The purpose of this study is to determine the characteristics of spirometric performance in a group of smokers and to carry out a prospective study of the changes in ventilatory lung function after smoking withdrawal. The ventilatory lung function was studied in 90 smokers and 30 non-smokers. Afterwards the smokers we...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1993-03-01 00:00:00
abstract：:A study was conducted to know the rate of non-compliance of antituberculosis therapy among HIV-infected patients, the factors associated with non-compliance and the evolution of these patients. The therapy compliance in 276 tuberculous HIV infected patients diagnosed in two Madrid hospitals was analyzed. Fifty-one pat...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1997-03-01 00:00:00
abstract：BACKGROUND:The RS3PE syndrome is a recently described uncommon disorder in the elderly patient; in the initial reports, it was characterized by an excellent prognosis with total remission. In contrast with rheumatoid arthritis and polymyalgia rheumatic, it has been related to HLA B7. Further works have questioned its b...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1999-12-01 00:00:00
abstract：:The polyacrylamide gel electrophoresis of spinal fluid from 488 patients suffering neurological diseases and from a control group are reviewed. One hundred and eleven cases (22.7%) showed oligoclonal bands (OB). The highest percentage of OB appeared in the group of patients with definite multiple sclerosis (84%), foll...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1989-10-01 00:00:00
abstract：:A patient who had been successfully treated of Hodgkin's disease (nodular sclerotic type) with mediastinal radiotherapy and polychemotherapy, suffered an acute pericarditis immediately after radiotherapy and a complete atrial-ventricular block 14 years later. Five years later she presented refractory hemorrhagic perit...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1991-10-01 00:00:00
abstract：INTRODUCTION:Obesity is a chronic, complex and multifactorial metabolic disease involved in the development of chronic noncommunicable diseases such as type 2 diabetes mellitus, cardiovascular disease and cancer. The care of individuals with obesity is an essential part of the holistic approach provided by internal med...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2020.06.008
更新日期：2020-07-25 00:00:00
abstract：BACKGROUND:Bartonella henselae infections are closely related to a number of clinical conditions of growing interest in our environment. As cats are the reservoir, and their bites and scratches are the main transmission mechanism, we attempted to study the seroepidemiology of the infection caused by this microorganism ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1998-12-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Quantification of stroke risk is not always performed in hypertensive patients in Primary Care. METHODS:This was an epidemiological study in hypertensive patients aged 55 years and older attending primary care centres in Spain. The D'Agostino Stroke Risk Scale, using data from the Framingham ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13128673
更新日期：2008-11-01 00:00:00
abstract：:Cutaneous larva migrans (CLM) is a frequent dermal disease in travelers, caused by larvae of nonhuman ancylostoma. We describe 34 outside cases of CLM diagnosed since January 1991 to June 2002. Nineteen male and female. Age: 35.7 years (20-60). The total number of CLM infestations was 73, 83.5% in feet. In five cases ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(04)71567-2
更新日期：2004-12-01 00:00:00
abstract：BACKGROUND:Despite a steady decrease in its incidence, pneumonia caused by Pneumocystis carinii (PCP) are still diagnosed, and they occur frequently in patients unaware of being infected with the human immunodeficiency virus (HIV). Since it is a disease with a high mortality risk, its early diagnosis and therapy would ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(02)71100-4
更新日期：2002-08-01 00:00:00
abstract：BACKGROUND:The presence of surface antigen of hepatitis B (HBsAg) virus in serum from recently vaccinated adults has been scarcely investigated. In this work, after the detection by chance of seven HBsAg-positive patients on hemodialysis who reported recent hepatitis B vaccination, a prospective study was undertaken to...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1999-04-01 00:00:00
abstract：OBJECTIVES:To assess the routine indication of chest roentgenogram after thoracentesis in function of iatrogenic pneumothorax causation, following a procedure protocol. PATIENTS AND METHODS:Prospective study of 104 consecutive thoracentesis procedures performed in 76 patients. The procedure was protocolized and after ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13044921
更新日期：2003-03-01 00:00:00
abstract：:We have screened a population of newborn babies without any previous apparent pathology in order to discover the distribution of alpha 1-anti-trypsin phenotypes (AAT) in our community. The research has been done on 457 babies born in the province of Valladolid, determining the plasma levels of AAT and the correspondin...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1989-02-01 00:00:00
abstract：:The clinical records of patients attended at emergency hospitals in fifteen hospitals in Madrid, Valencia and Gran Canaria during 1994 were retrospectively analyzed. Seventy-three emergencies related to the consumption of design drugs, hallucinogens or amphetamines (100 times lower than because of opiates or cocaine) ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1997-12-01 00:00:00
abstract：:Inflammatory pseudotumor (IP) is a rare pathological entity. Although, the pulmonary affection is the most frequent, any other organ can be involved. Its etiopathology is unknown. The disease is considered as a reactive process constituted by chronic inflammatory elements and a benign behavior. The lack of a specific ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1991-12-01 00:00:00
abstract：:Despite its high frequency, there is not a consensus for the management of a patient with mild head trauma. In this prospective study we analyzed wether the transient loss of consciousness was associated with a higher risk of cranioencephalic injury in function of patient's age. Fifty-two patients with a Glasgow score...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1999-10-01 00:00:00
abstract：OBJECTIVES:To ascertain the correlation between the partial pressure of oxygen (PaO2) and oxyhaemoglobin saturation by pulse oximetry (SpO2) in patients who were admitted to the emergency department with suspected acute respiratory failure. MATERIAL AND METHODS:A prospective, observational multicentre study was conduc...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2017.08.006
更新日期：2017-12-01 00:00:00
