Abstract：
:The purpose of this study is to determine the characteristics of spirometric performance in a group of smokers and to carry out a prospective study of the changes in ventilatory lung function after smoking withdrawal. The ventilatory lung function was studied in 90 smokers and 30 non-smokers. Afterwards the smokers were included in smoking withdrawal program. One year later, the ventilatory function tests were repeated in those individuals who were able to stop smoking. Respiratory function tests were likewise repeated in 10 subjects chosen randomly among those who were not able to stop smoking. The initial study of the ventilatory lung function showed that smokers had significantly lower values of FVC (p < 0.001), FEV1 (p < 0.001), FEVC1/FVC (p < 0.001), FEF25-75 (p < 0.01 and PEF (p < 0.01) compared to non-smokers. Likewise smokers also had a statistically significant higher prevalence rate of obstructive pulmonary disease (p < 0.001). Ventilatory function studies performed one year after smoking withdrawal on those who were able to stop smoking showed a significant improvement of respiratory function parameters compared to studies done one year before. There was also a significant decrease in the prevalence and severity of obstructive pulmonary disease. No differences were observed in the ventilatory function tests performed on the ten subjects who did not stop smoking. From these data we suggest that tobacco consumption produces obstruction of the airways that can be reverted, at least in part, after smoking withdrawal.
journal_name
Rev Clin Espjournal_title
Revista clinica espanolaauthors
Aparici M,Fernández González AL,Alegría Esubject
Has Abstractpub_date
1993-03-01 00:00:00pages
169-72issue
4eissn
0014-2565issn
1578-1860journal_volume
192pub_type
杂志文章abstract：:Hereditary hemorrhagic telangiectasia (HHT) is a hereditary dominant autosoma clinical entity characterized by repeated hemorrhages (being epistaxis the more frequent) and telangiectasia in skin, mucosa and internal organs. Incidence in Europe is 1,2 per 100,000 pop. We discuss the experience of an Internal Medicine D...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
abstract：:We studied fifty seven episodes of cirrhotic spontaneous bacterial peritonitis in order to know its microbiological, clinical and evolutive characteristics. One third of the patients had presented some previous peritonitis episodes. Ninety three percent of the patients referred some symptoms at time of diagnosis. Asci...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1990-11-01 00:00:00
abstract：:A study was carried out during five months in La Paz Hospital with the objective to know the proportion of admissions due to an adverse reaction to pharmaceutical drugs (RAM) or due to an acute drug intoxication. For this purpose the reports of all patients seen at the Medical Emergency Room were analyzed on a daily b...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1991-01-01 00:00:00
abstract：:Our objective has been to elaborate an updated Clinical Guide of the Spanish Society of Internal Medicine (SEMI) for the prevention and treatment of glucocorticoids-induced osteoporosis (GIO), identifying and measuring the grade of evidence that supports the given recommendations. For this, we reviewed studies perform...
journal_title：Revista clinica espanola
pub_type： 杂志文章,实务指引
doi：10.1157/13115006
更新日期：2008-01-01 00:00:00
abstract：:The use of anti-lymphocyte globulins (ATG, ALG, OKT3) for the control or organ rejection in humans, has been of major importance both in preventing and treating organ rejection resistant to other treatments. We present here the results of our immunosuppression protocol using two different therapeutic associations. To ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1990-02-01 00:00:00
abstract：BACKGROUND:The immune response to Mycobacterium tuberculosis is primarily mediated by T lymphocytes. In this study an investigation was made of T lymphocytes and their subsets, B lymphocytes and natural cytotoxic cells (Natural Killer, NK) in blood and organic fluids in different tuberculosis conditions. METHODS:Patie...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1996-04-01 00:00:00
abstract：OBJECTIVES:The aim of this study was to assess the available evidence on the validity, diagnostic accuracy and clinical utility of the multitarget DNA test in faeces (Cologuard™) for screening for colorectal cancer (CRC). MATERIAL AND METHODS:A systematic review was performed by consulting MedLine, EMBASE and Web of S...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2015.08.002
更新日期：2015-12-01 00:00:00
abstract：OBJECTIVE:The objective of this study was to determine the prognostic factors in relationship to evolution to death of bacteremia-fungemia (BF) episodes occurred in 1986 and to compare them with the results obtained ten years later in 1996. PATIENTS AND METHODS:Prospective study of all BF episodes observed at Hospital...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/s0014-2565(01)70765-5
更新日期：2001-03-01 00:00:00
abstract：OBJECTIVES:Heart failure decompensation is the most common reason for hospitalization in persons over 65 years old. There is limited information on the prevalence of precipitating factors of heart failure decompensation in this population. In this study we prospectively examined the factors associated with decompensati...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2010.04.020
更新日期：2010-11-01 00:00:00
abstract：:215 cases diagnosed of human leptospirosis in the Camagüey Province, Cuba, are studied, for the period between 1986 and 1990. The clinical and epidemiological features are studied, together with the anatomopathological study of the decreased. The most frequent complications and the treatment employed, including prophy...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
abstract：:HepatitisC virus infection is a significant public health problem. The introduction of direct-acting antiviral agents, whose efficacy is greater than 90% in all patient groups (including those with cirrhosis), has represented a highly relevant change compared with classical interferon-based therapies. Tolerance for th...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2017.07.006
更新日期：2018-01-01 00:00:00
abstract：INTRODUCTION:The role of glucose elevation above levels considered normal in non- diabetic patients with acute coronary syndromes (ACS) is not adequately defined. The aim of this study was to determine the association between serum glucose at admission and 1-year mortality in this type of patients. METHODS:We studied ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13088586
更新日期：2006-06-01 00:00:00
abstract：:A 67-year-old woman with a history of hypertension, hyperlipidemia and 6 years of evolution of type 2 diabetes mellitus presented with fever, purulent sputum and right chest pain. She was on treatment with metformin 850 mg/bid, glimepiride 4 mg/day, candesartan 16 mg/day, atorvastatin 10mg/day and acetylsalicylic acid...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2011.05.014
更新日期：2012-02-01 00:00:00
abstract：:The purpose of this study was to review the epidemiological aspects and the characteristics of the thyroid disfunction produced by amiodarone in Catalonia, an area with type I endemic goiter. For this purpose, three groups of patients have been studied: 1) 102 patients with prolonged amiodarone treatment, out of whom ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1991-02-01 00:00:00
abstract：:The present design is a descriptive study in which people bitten by animals, rabies treatment used and the reactions to it are described. The frequency of adverse effects to the vaccine and to the serum are pointed out. The forms of clinical presentation and the clinical symptoms of the reactions observed in the Ciego...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13058826
更新日期：2004-03-01 00:00:00
abstract：:Type 2 diabetes mellitus is a major health problem with high prevalence, morbidity and mortality, and its medical treatment is growing in complexity due to patients' diverse clinical conditions. This article presents a consensus document by the Diabetes, Obesity and Nutrition Group of the Spanish Society of Internal M...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1016/j.rce.2020.06.005
更新日期：2020-07-13 00:00:00
abstract：:The use of ambulatory monitorization of blood pressure has shown the importance of the alarm reaction or white coat reaction and its conditioning factors in some patients. The influence of place (medical facility or home) and person who performs the procedure (doctor or nurse) on the taking of blood pressure is studie...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1994-03-01 00:00:00
abstract：:We report the clinical, radiological and microbiological features of ten patients diagnosed of pyogenic sacroiliitis in an Internal Medicine Department during a 13 years period. Clinical signs and radiological or scintigraphical findings were present in every case. Staphylococcus aureus was isolated in blood cultures ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1993-10-01 00:00:00
abstract：:We reviewed cases with Rendu-Osler disease or hereditary hemorrhagic telangiectasia (HHT) between 1976 and 1989 in our area of internal medicine. Of the ten reported cases, six presented severe iron deficiency anemia-three as a result of repeated and intense epistaxis and the rest as a result of digestive losses. The ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1993-12-01 00:00:00
abstract：:In the present work we study the modifications in hydrosaline metabolism which occurred in two groups of healthy male individuals, one consisting of 15 young men (mean age of 20 years) and the other of 30 elderly subjects (mean age of 75 years) when the thirst test was performed for 48 hours. After performing the thir...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1991-07-01 00:00:00
abstract：:Fibromyalgia or fibromyalgic syndrome (FMS) is a clinical picture of unknown origin that is characterized by generalized, incapacitating and chronic pain together with the demonstration in the physical examination of previously defined points in which moderate pressure causes pain, called fibromyalgia tender points (F...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13077119
更新日期：2005-07-01 00:00:00
abstract：:Sarcoidosis is a disease which presents important clinical differences according to its geographical distribution. Thus, the objective of this study was to evaluate the epidemiologic, clinical, radiologic, and diagnostic characteristics in a series of 30 sarcoidosis patients in the province of Salamanca (representing ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1991-09-01 00:00:00
abstract：:The contributions of Santiago Ramon y Cajal to Modern medicine are innumerable. This large scientist and humanist, a man ahead of his time, spoke for the first time such concepts as angiogenesis, which represents one of the most innovative fields for oncology today, in addition to conducting experimental research on t...
journal_title：Revista clinica espanola
pub_type： 传,历史文章,杂志文章
doi：10.1016/s0014-2565(08)76037-5
更新日期：2008-12-01 00:00:00
abstract：OBJECTIVE:To know the rate of occurrence of monoclonal bands in a clinical laboratory as an estimate of monoclonal gammopathy incidence, and to detect the proportion of these bands in which an explicit clinical diagnosis or follow-up request is not established. Other objectives are to describe its distribution and the ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13075569
更新日期：2005-05-01 00:00:00
abstract：:A retrospective study is presented of 19 patients who suffered Hypercortisolism who were examined by adrenal gammagraphy, echography, and CT scan in order to evaluate the usefulness of gammagraphy in the diagnostic approximation of this pathology. The gammagraphy findings had an excellent correlation with anatomopatho...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1991-04-01 00:00:00
abstract：INTRODUCTION:Geographic tongue (GT) is a lesion of unknown origin associated with systemic diseases and therefore involves multidisciplinary care. METHODS:We performed a literature search of the PubMed, EMBASE, Web of Science and Cochrane databases. The selection criteria were consistent with the Preferred Reporting I...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：10.1016/j.rce.2018.05.006
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND:In recent years, there has been an increase of drugs poisoning cases seen in the Emergency Department. This study has aimed to evaluate the characteristics of these cases in the Ramón and Cajal Hospital in Madrid. MATERIALS AND METHODS:A descriptive analysis about the drug poisonings diagnosed in 2004 was p...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：10.1157/13127603
更新日期：2008-10-01 00:00:00
abstract：:Diabetes mellitus (DM) is characterized by a hypercoagulability state and many of these disorders are corrected with adequate metabolic control. The goal of this study was to assess diverse hemostatic and fibrinolytic parameters in 12 insulin-dependent (IDDM) metabolically controlled patients without vascular lesions ...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1989-02-01 00:00:00
abstract：:Cyclophosphamide is used both in the treatment of malignant and non-malignant diseases. Urinary neoplasms secondary to its use have been described. We discuss the case of a patient with panarteritis nodosa treated with cyclophosphamide during 63 months, with a total dose of 210 grams, and that showed a bladder neoplas...
journal_title：Revista clinica espanola
pub_type： 杂志文章,评审
doi：
更新日期：1992-05-01 00:00:00
abstract：:Two patients with advanced atherosclerotic vascular disease developed multiple cholesterol emboli. In both patients the clinical presentation included livedo reticularis of the lower part of the body and purple toes with small areas of distal necrosis and ulceration. The predisposing factors are operative vascular pro...
journal_title：Revista clinica espanola
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
