Abstract:
OBJECTIVE:The objective of this study was to determine the prognostic factors in relationship to evolution to death of bacteremia-fungemia (BF) episodes occurred in 1986 and to compare them with the results obtained ten years later in 1996. PATIENTS AND METHODS:Prospective study of all BF episodes observed at Hospital Universitario La Princesa, Madrid, during the 1985-1986 and 1996-1997 periods. The same definitions were used for the two study periods. The univariate analysis of results was performed with the chi square test and variables with statistical significance with p < 0.10 in the multivariate analysis with the logistic regression model. RESULTS:A total of 984 episodes were analyzed. There was an increased incidence per 1,000 admissions from 23.58 to 28.44. A change in the relationship of nosocomial acquisition (55.5%-42.6%) to community-acquired episodes (44.1%-57.4%) and an increase in gram-positive organisms (39%-48.6%) compared with gram-negative organisms (53.4%-41.8%) was observed. The organisms recovered most frequently in both periods were Escherichia coli and coagulase-negative Staphylococcus. An overall decrease of mortality rate from 26.2% down to 15.9% (OR: 4.52) was noted. Independent factors with poor prognosis in the first period included age over 60 years (OR: 4.52), underlying disease (OR: 2.79; more than one OR: 6.53), respiratory source (OR: 3.86), DIC (OR: 4.79), hypotension (OR: 3.19); as for the second period, the corresponding independent factors included age > 60 years (OR: 6.48), nosocomial acquisition (OR: 2.62), DIC (OR: 18.7), hypotension (OR: 3.07), and inadequate surgical treatment (OR: 7.61). CONCLUSIONS:In the last ten years the incidence of BF episodes has increased. In contrast, mortality rate has decreased. Factors with poor prognosis, including age > 60, DIC, and hypotension, still persist.
journal_name
Rev Clin Espjournal_title
Revista clinica espanolaauthors
Noguerado Asensio A,Ruiz Giardin JM,Pizarro Portillo A,Méndez García J,la Hulla Pastor F,Fernández Escribano M,Hernández Schurman F,San Martín López JV,Hernández Schurman I,Alvarez Orejón J,Rodríguez Salvanes Fdoi
10.1016/s0014-2565(01)70765-5keywords:
subject
Has Abstractpub_date
2001-03-01 00:00:00pages
122-9issue
3eissn
0014-2565issn
1578-1860pii
S0014-2565(01)70765-5journal_volume
201pub_type
杂志文章abstract::We studied fifty seven episodes of cirrhotic spontaneous bacterial peritonitis in order to know its microbiological, clinical and evolutive characteristics. One third of the patients had presented some previous peritonitis episodes. Ninety three percent of the patients referred some symptoms at time of diagnosis. Asci...
journal_title:Revista clinica espanola
pub_type: 杂志文章
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abstract::Fibromyalgia or fibromyalgic syndrome (FMS) is a clinical picture of unknown origin that is characterized by generalized, incapacitating and chronic pain together with the demonstration in the physical examination of previously defined points in which moderate pressure causes pain, called fibromyalgia tender points (F...
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journal_title:Revista clinica espanola
pub_type: 杂志文章,多中心研究
doi:10.1157/13109839
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abstract:BACKGROUND:Adenosine deaminase (ADA) is a key enzyme in cellular immunity. It catalyses the reaction 2'deoxyadenosine to 2'deoxiinosine, a critical step in the production of essential metabolites for the synthesis of nucleic acids. Its main physiological activity occurs in T cells of lymphoid tissue. The advanced HIV i...
journal_title:Revista clinica espanola
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abstract::Cyclophosphamide is used both in the treatment of malignant and non-malignant diseases. Urinary neoplasms secondary to its use have been described. We discuss the case of a patient with panarteritis nodosa treated with cyclophosphamide during 63 months, with a total dose of 210 grams, and that showed a bladder neoplas...
journal_title:Revista clinica espanola
pub_type: 杂志文章,评审
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abstract::Sarcoidosis is a disease which presents important clinical differences according to its geographical distribution. Thus, the objective of this study was to evaluate the epidemiologic, clinical, radiologic, and diagnostic characteristics in a series of 30 sarcoidosis patients in the province of Salamanca (representing ...
journal_title:Revista clinica espanola
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更新日期:1991-09-01 00:00:00
abstract::Anisakis simplex is a nematode which parasitizes mainly fish and cephalopods and accidentally human beings after ingestion. Apart from the different digestive syndromes, this organism has recently been involved as cause of IgE-mediated allergic reactions of variable degree (urticaria to severe angioedema). In this rep...
journal_title:Revista clinica espanola
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journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1998-12-01 00:00:00
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journal_title:Revista clinica espanola
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journal_title:Revista clinica espanola
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journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1992-05-01 00:00:00
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journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1992-09-01 00:00:00
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journal_title:Revista clinica espanola
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doi:
更新日期:1997-08-01 00:00:00
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journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1016/j.rce.2010.02.008
更新日期:2010-07-01 00:00:00
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journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1992-11-01 00:00:00
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journal_title:Revista clinica espanola
pub_type: 杂志文章,评审
doi:
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journal_title:Revista clinica espanola
pub_type: 杂志文章
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journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1157/13084760
更新日期:2006-01-01 00:00:00
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journal_title:Revista clinica espanola
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journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
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journal_title:Revista clinica espanola
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journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1157/13119912
更新日期:2008-05-01 00:00:00
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journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1991-06-01 00:00:00
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journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1016/j.rce.2016.01.002
更新日期:2016-05-01 00:00:00
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journal_title:Revista clinica espanola
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更新日期:2017-04-01 00:00:00
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journal_title:Revista clinica espanola
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doi:
更新日期:1999-12-01 00:00:00
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journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:10.1157/13128673
更新日期:2008-11-01 00:00:00
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journal_title:Revista clinica espanola
pub_type: 杂志文章
doi:
更新日期:1989-04-01 00:00:00
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journal_title:Revista clinica espanola
pub_type: 杂志文章,评审
doi:
更新日期:1991-03-01 00:00:00